Phospholipase D2 modulates agonist-induced μ-opioid receptor desensitization and resensitization

Journal of Neurochemistry

Volumn 88, Issue 3, 2004, Pages 680-688

  Koch, Thomas ^a   Brandenburg, Lars Ove ^a   Liang, Yingjian ^a   Schulz, Stefan ^a   Beyer, Andrea ^a   Schröder, Helmut ^a   Höllt, Volker ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

opioid receptor; Desensitization; Endocytosis; Internalization; Phospholipase D2; Resensitization

Indexed keywords

ENKEPHALIN DERIVATIVE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; PHOSPHOLIPASE D2; PROTEIN HAMOR1; RETINA S ANTIGEN; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN;

ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; DOMINANT INHERITANCE; ENDOCYTOSIS; ENZYME ACTIVATION; ENZYME REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LONG TERM EXPOSURE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; RECEPTOR SENSITIVITY;

1-BUTANOL; ANALGESICS, OPIOID; ANIMALS; CELL LINE; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; HUMANS; PHOSPHATIDIC ACIDS; PHOSPHOLIPASE D; PROTEIN ISOFORMS; RATS; RECEPTORS, OPIOID, MU;

EID: 0942287665     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02189.x     Document Type: Article

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