μ-Opioid receptor down-regulation and tolerance are not equally dependent upon G-protein signaling

Pharmacology Biochemistry and Behavior

Volumn 72, Issue 1-2, 2002, Pages 273-278

  Gomes, Benedict A ^a   Shen, Ji ^a   Stafford, Kristi ^a   Patel, Minesh ^a   Yoburn, Byron C ^a  

^a ST JOHN'S UNIVERSITY   (United States)

Author keywords

G proteins; Opioid tolerance; Pertussis toxin; PTX; Opioid down regulation

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MU OPIATE RECEPTOR; PERTUSSIS TOXIN; ETORPHINE; MORPHINE;

ANIMAL; ARTICLE; COMPARATIVE STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG TOLERANCE; MALE; MESENCEPHALON; METABOLISM; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPINAL CORD; ANALGESIA; ANIMAL TISSUE; BRAIN; CONTROLLED STUDY; DRUG INFUSION; DRUG POTENCY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; TAIL FLICK TEST;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG TOLERANCE; GTP-BINDING PROTEINS; MALE; MESENCEPHALON; MICE; PERTUSSIS TOXIN; RECEPTORS, OPIOID, MU; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 0036202059     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(01)00757-2     Document Type: Article

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