The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI

Nature Structural Biology

Volumn 7, Issue 2, 2000, Pages 122-126

  Scheffzek, Klaus ^a,b,c   Stephan, Ilona ^d   Jensen, Ole N ^e   Illenberger, Daria ^d   Gierschik, Peter ^d  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d UNIVERSITY OF ULM   (Germany)

^e UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MAGNESIUM ION; RAC PROTEIN; RHO FACTOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; COMPLEX FORMATION; CRYSTAL STRUCTURE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN SECRETION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; LIPID METABOLISM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEINS; RAC GTP-BINDING PROTEINS; RHO GTP-BINDING PROTEINS;

EID: 0343750716     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/72392     Document Type: Article

References (39)

1. Van Aelst, L. & D'Souza-Schorey, C. Genes Dev. 11, 2295-2322 (1997).
2. Bourne, H.R. & Sanders, D.A. Nature 348, 125-131 (1990).
3. Scherle, P., Behrens, T. & Staudt, L.M. Proc. Natl. Acad. Sci. USA 90, 7568-7572 (1993).
4. Keep, N.H. et al. Structure S, 623-633 (1997).
5. Gosser, Y.Q. et al. Wature387, 814-819 (1997).
6. Danley, D.E., Chuang, T.H. S Bokoch, G.M.J. Immunol. 157, 500-503 (1996).
7. Wei, Y. et al. Wature Struct. Biol. 4, 699-703 (1997).
8. Platko, J.V. et al. Proc. Natl. Acad. Sei. USA 90,2974-2978 (1995).
9. Na, S. et al. J. Biol. Chem. 271.11209-11213 (1996).
10. Wu, W.J., Leonard, D.A., Cerione, R.A. & Manor, D. J. Biol. Chem. 272, 26153-261538(1997).
11. Hirshberg, M., Stockley, R.W, Dodson, G. & Webb. M.R. Wature Struct. Biol. 4, 147-152(1997).
12. Ueda, T., Kikuchi, A., Ohga, N., Yamamoto, J. & Takai, Y. J. Biol. Chem. 265, 9373-9380 (1990).
13. Sasaki, T., Kalo, M. & Takai, Y.J. Biol. Chem. 268,23959-23963 (1993).
14. Chuang, T.H., Xu, X., Knaus, U.G., Hart, M.J. & Bokoch, G.M. J. Biol. Chem. 268, 775-778(1993).
15. Newcombe, A.R., Stockley, R.W., Hunter, J.L & Webb, M.R. Biochemistry 38, 6879-6886(1999).
16. Hancock, J.F. & Hall, A. EMBOJ. 12,1915-1921 (1993).
17. Nomanbhoy, T.K. & Cerione, R.A. J. Biol. Chem. 271,10004-10009 (1996).
18. Hart, M.J. et al. Science 258, 812-815(1992).
19. Rittinger, K., Walker, P.A., Eccleston, if., Smerdon, S.J. & Gamblin, S.J. Wature 389,758-762(1997).
20. Kikuchi, A. et al. J. Biol. Chem. 267,14611-14615 (1992).
21. Li, R. & Zheng, Y. J. Biol. Chem. 272,4671-4679 (1997).
22. Boriack-Sjodin, A., Margarit, S.M., Bar-Sagi, D. & Kuriyan, J. Wature 394, 337-343 (1998).
23. Goldberg, J. Cell 95, 237-248 (1998).
24. Abdul-Manan, N. et al. Wature 399, 379-383 (1999). .
25. Mott, H.R. et al. Wature 399,384-388 (1999).
26. Hori, Y. et al. Oncogene 6, 515-522 (1991).
27. Nomanbhoy, T.K., Erickson. J.W. & Cerione. R.A. Biochemistry 38, 1744-1750 (1999).
28. Feltham, J.L. eta/. Biochemistry 36, 8755-8766 (1997).
29. Geyer, M., eta/. Biochemistry. 35,10308-10320 (1996).
30. Tanaka. K., Sasaki, T. & Takai, Y. Methods Enzymol. 256,41-49 (1995).
31. Illenberger, D. eta/. EMBOj.M, 6241-6249 (1998).
32. Kabsch, W.J. Appl. Crystallogr. 26, 795-800 (1993).
33. Collaborative Computational Project Number 4. CCP4 suite: programs for protein crystallography. Acte Crystallogr. D 50, 760-763 (1994).
34. Jones, T.A. & Kjelgaard, M. Methods Enzymol. 277,173-208 (1997).
35. Brunger, A.T. eta/, Acta Crystallogr. D 54, 905-921 (1998).
36. Kraulis, P.J. J. Appl.Crystallogr. 24, 946-950 (1991).
37. Merrit, E.A. & Bacon, D.J. Methods Enzymol. 277, 505-524 (1997).
38. Nicholls, A., Sharp, K.A & Honig, B. Proteins Struct Funct. Genet. 11, 281-296 (1991).
39. Longenecker, K. eta/. Acta Crystallogr. D 55,1503-1515 (1999).