메뉴 건너뛰기




Volumn 52, Issue 12, 2007, Pages 753-762

Defects of mitochondrial electron transport chain in bipolar disorder: Implications for mood-stabilizing treatment

Author keywords

Bipolar disorder; Mitochondrial electron transport chain; Mood stabilizing drugs; Neuroprotection; Oxidative damage; Reactive oxygen species

Indexed keywords

CARBAMAZEPINE; LAMOTRIGINE; LITHIUM; MOOD STABILIZER; OLANZAPINE; REACTIVE OXYGEN METABOLITE; VALPROIC ACID;

EID: 37749029999     PISSN: 07067437     EISSN: 14970015     Source Type: Journal    
DOI: 10.1177/070674370705201202     Document Type: Review
Times cited : (44)

References (109)
  • 1
    • 0038281515 scopus 로고    scopus 로고
    • Suicidal behaviour in bipolar disorder: Risk and prevention
    • Tondo L, Isacsson G, Baldessarini R. Suicidal behaviour in bipolar disorder: risk and prevention. CNS Drugs. 2003;17:491-511.
    • (2003) CNS Drugs , vol.17 , pp. 491-511
    • Tondo, L.1    Isacsson, G.2    Baldessarini, R.3
  • 2
    • 0036280163 scopus 로고    scopus 로고
    • Mortality of patients with mood disorders: Follow-up over 34-38 years
    • Angst F, Stassen HH, Clayton PJ, et al. Mortality of patients with mood disorders: follow-up over 34-38 years. J Affect Disord. 2002;68:167-181.
    • (2002) J Affect Disord , vol.68 , pp. 167-181
    • Angst, F.1    Stassen, H.H.2    Clayton, P.J.3
  • 3
    • 0842266735 scopus 로고    scopus 로고
    • Economic grand rounds: The economic burden of bipolar disorder
    • Stimmel GL. Economic grand rounds: the economic burden of bipolar disorder. Psychiatr Serv. 2004;55:117-118.
    • (2004) Psychiatr Serv , vol.55 , pp. 117-118
    • Stimmel, G.L.1
  • 4
    • 0034531055 scopus 로고    scopus 로고
    • The economic burden of bipolar disease
    • Woods SW. The economic burden of bipolar disease. J Clin Psychiatry. 2000;61(Supp 13):38-41.
    • (2000) J Clin Psychiatry , vol.61 , Issue.SUPP 13 , pp. 38-41
    • Woods, S.W.1
  • 5
    • 0031023930 scopus 로고    scopus 로고
    • The anatomy of mood disorders eview of structural neuroimaging studies
    • Soares JC, Mann JJ. The anatomy of mood disorders eview of structural neuroimaging studies. Biol Psychiatry. 1997;41:86-106.
    • (1997) Biol Psychiatry , vol.41 , pp. 86-106
    • Soares, J.C.1    Mann, J.J.2
  • 6
    • 0031782081 scopus 로고    scopus 로고
    • Neuroimaging abnormalities in the subgenual prefrontal cortex: Implications for the pathophysiology of familial mood disorders
    • Drevets WC, Ongur D, Price JL. Neuroimaging abnormalities in the subgenual prefrontal cortex: implications for the pathophysiology of familial mood disorders. Mol Psychiatry. 1998;3:220-226, 190-191.
    • (1998) Mol Psychiatry , vol.3
    • Drevets, W.C.1    Ongur, D.2    Price, J.L.3
  • 8
    • 0030935403 scopus 로고    scopus 로고
    • Subgenal prefrontal cortex abnormalities in mood disorders
    • Drevets WC, Price JL, Simpson JR, et al. Subgenal prefrontal cortex abnormalities in mood disorders. Nature. 1997;386:824-827.
    • (1997) Nature , vol.386 , pp. 824-827
    • Drevets, W.C.1    Price, J.L.2    Simpson, J.R.3
  • 9
    • 0031590701 scopus 로고    scopus 로고
    • Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients
    • Rajkowska G. Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients. Ann N Y Acad Sci. 1997;836:253-268.
    • (1997) Ann N Y Acad Sci , vol.836 , pp. 253-268
    • Rajkowska, G.1
  • 10
    • 0030862061 scopus 로고    scopus 로고
    • The functional neuroanatomy of mood disorders
    • Soares JC, Mann JJ. The functional neuroanatomy of mood disorders. J Psychiatr Res. 1997;31:393-432.
    • (1997) J Psychiatr Res , vol.31 , pp. 393-432
    • Soares, J.C.1    Mann, J.J.2
  • 11
    • 0035336748 scopus 로고    scopus 로고
    • Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder
    • Rajkowska G, Halaris A, Selemon LD. Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder. Biol Psychiatry. 2001;49:741-752.
    • (2001) Biol Psychiatry , vol.49 , pp. 741-752
    • Rajkowska, G.1    Halaris, A.2    Selemon, L.D.3
  • 12
    • 0032527572 scopus 로고    scopus 로고
    • A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives
    • Benes FM, Kwok EW, Vincent SL, et al. A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives. Biol Psychiatry. 1998;44:88-97.
    • (1998) Biol Psychiatry , vol.44 , pp. 88-97
    • Benes, F.M.1    Kwok, E.W.2    Vincent, S.L.3
  • 13
    • 0035884325 scopus 로고    scopus 로고
    • The density of pyramidal and nonpyramidal neurons in anterior cingulate cortex of schizophrenic and bipolar subjects
    • Benes FM, Vincent SL, Todtenkopf M. The density of pyramidal and nonpyramidal neurons in anterior cingulate cortex of schizophrenic and bipolar subjects. Biol Psychiatry. 2001;50:395-406.
    • (2001) Biol Psychiatry , vol.50 , pp. 395-406
    • Benes, F.M.1    Vincent, S.L.2    Todtenkopf, M.3
  • 14
    • 0032573166 scopus 로고    scopus 로고
    • Glial reduction in the subgenual prefrontal cortex in mood disorders
    • Ongur D, Drevets WC, Price JL. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proc Natl Acad Sci USA 1998;95:13290-13295.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13290-13295
    • Ongur, D.1    Drevets, W.C.2    Price, J.L.3
  • 15
    • 34250197821 scopus 로고    scopus 로고
    • Neuron somal size is decreased in the lateral amygdalar subnucleus from subjects with bipolar disorder
    • Bezchlibnyk YB, Sun X, Wang JF, et al. Neuron somal size is decreased in the lateral amygdalar subnucleus from subjects with bipolar disorder. J Psychiatry Neurosci. 2007;32:203-210.
    • (2007) J Psychiatry Neurosci , vol.32 , pp. 203-210
    • Bezchlibnyk, Y.B.1    Sun, X.2    Wang, J.F.3
  • 16
    • 24144464489 scopus 로고    scopus 로고
    • Production of reactive oxygen species in brain mitochondria: Contribution by electron transport chain and non-electron transport chain sources
    • Adam-Vizi V. Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources. Antioxid Redox Signal. 2005;7:1140-1149.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1140-1149
    • Adam-Vizi, V.1
  • 17
    • 0042233907 scopus 로고    scopus 로고
    • Structural organization of the mitochondrial respiratory chain
    • Genova ML, Bianchi C, Lenaz G. Structural organization of the mitochondrial respiratory chain. Ital J Biochem. 2003;52:58-61.
    • (2003) Ital J Biochem , vol.52 , pp. 58-61
    • Genova, M.L.1    Bianchi, C.2    Lenaz, G.3
  • 18
    • 0036139981 scopus 로고    scopus 로고
    • Respiratory chain supercomplexes
    • Schagger H. Respiratory chain supercomplexes. IUBMB Life. 2001;52:119-128.
    • (2001) IUBMB Life , vol.52 , pp. 119-128
    • Schagger, H.1
  • 19
    • 27544474355 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain and free radical generation in stroke
    • Moro MA, Almeida A, Bolanos JP, et al. Mitochondrial respiratory chain and free radical generation in stroke. Free Radic Biol Med. 2005 15;39:1291-1304.
    • (2005) Free Radic Biol Med , vol.15 , Issue.39 , pp. 1291-1304
    • Moro, M.A.1    Almeida, A.2    Bolanos, J.P.3
  • 20
    • 0026795635 scopus 로고
    • Protein oxidation and aging
    • Stadtman ER. Protein oxidation and aging. Science. 1992;257:1220-1224.
    • (1992) Science , vol.257 , pp. 1220-1224
    • Stadtman, E.R.1
  • 21
    • 0023886170 scopus 로고
    • DNA damage and oxygen radical toxicity
    • Imlay JA, Linn S. DNA damage and oxygen radical toxicity. Science. 1988;240;1302-1309.
    • (1988) Science , vol.240 , pp. 1302-1309
    • Imlay, J.A.1    Linn, S.2
  • 22
    • 0033402469 scopus 로고    scopus 로고
    • Excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin
    • Skaper SD, Floreani M, Ceccon M, et al. Excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin. Ann NY Acad Sci. 1999;890:107-118.
    • (1999) Ann NY Acad Sci , vol.890 , pp. 107-118
    • Skaper, S.D.1    Floreani, M.2    Ceccon, M.3
  • 23
    • 0028609847 scopus 로고
    • Oxygen free radicals and neurodegeneration in Parkinson's disease: A role for nitric oxide
    • Youdim MB, Lavie L, Riederer P. Oxygen free radicals and neurodegeneration in Parkinson's disease: a role for nitric oxide. Ann NY Acad Sci. 1994;738:64-68.
    • (1994) Ann NY Acad Sci , vol.738 , pp. 64-68
    • Youdim, M.B.1    Lavie, L.2    Riederer, P.3
  • 24
    • 0031711224 scopus 로고    scopus 로고
    • Excitotoxicity and nitric oxide in Parkinson's disease pathogenesis
    • Beal MF. Excitotoxicity and nitric oxide in Parkinson's disease pathogenesis. Ann Neurol. 1998;44:110-114.
    • (1998) Ann Neurol , vol.44 , pp. 110-114
    • Beal, M.F.1
  • 25
    • 0034018813 scopus 로고    scopus 로고
    • Shimohama S. Apoptosis in Alzheimer's disease-an update. Apoptosis. 2000;5:9-16.
    • Shimohama S. Apoptosis in Alzheimer's disease-an update. Apoptosis. 2000;5:9-16.
  • 27
  • 28
    • 0035054355 scopus 로고    scopus 로고
    • Oxidative damage and schizophrenia: An overview of the evidence and its therapeutic implications
    • Yao JK, Reddy RD, van Kammen DP. Oxidative damage and schizophrenia: an overview of the evidence and its therapeutic implications. CNS Drugs. 2001;15:287-310.
    • (2001) CNS Drugs , vol.15 , pp. 287-310
    • Yao, J.K.1    Reddy, R.D.2    van Kammen, D.P.3
  • 29
    • 0037783987 scopus 로고    scopus 로고
    • Dopamine-induced oxidative stress in neurons with glutathione deficit: Implication for schizophrenia
    • Grima G, Benz B, Parpura V, et al. Dopamine-induced oxidative stress in neurons with glutathione deficit: implication for schizophrenia. Schizophr Res. 2003;62:213-224.
    • (2003) Schizophr Res , vol.62 , pp. 213-224
    • Grima, G.1    Benz, B.2    Parpura, V.3
  • 30
    • 33644953299 scopus 로고    scopus 로고
    • Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme
    • Chinopoulos C, Adam-Vizi V. Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme. FEBS J. 2006;273:433-450.
    • (2006) FEBS J , vol.273 , pp. 433-450
    • Chinopoulos, C.1    Adam-Vizi, V.2
  • 32
    • 33745591102 scopus 로고    scopus 로고
    • Multiple pathways of cytochrome c release from mitochondria in apoptosis
    • Gogvadze V, Orrenius S, Zhivotovsky B. Multiple pathways of cytochrome c release from mitochondria in apoptosis. Biochim Biophys Acta. 2006;1757:639-647.
    • (2006) Biochim Biophys Acta , vol.1757 , pp. 639-647
    • Gogvadze, V.1    Orrenius, S.2    Zhivotovsky, B.3
  • 33
    • 0026453704 scopus 로고
    • Brain phosphorous metabolism in depressive disorders detected by phosphorus-31 magnetic resonance spectroscopy
    • Kato T, Takahashi S, Shioiri T, et al. Brain phosphorous metabolism in depressive disorders detected by phosphorus-31 magnetic resonance spectroscopy. J Affect Disord. 1992;26:223-230.
    • (1992) J Affect Disord , vol.26 , pp. 223-230
    • Kato, T.1    Takahashi, S.2    Shioiri, T.3
  • 34
    • 0028352678 scopus 로고
    • Reduction of brain phosphocreatine in bipolar II disorder detected by phosphorus-31 magnetic resonance spectroscopy
    • Kato T, Takahashi S, Shioiri T, et al. Reduction of brain phosphocreatine in bipolar II disorder detected by phosphorus-31 magnetic resonance spectroscopy. J Affect Disord. 1994;31:125-133.
    • (1994) J Affect Disord , vol.31 , pp. 125-133
    • Kato, T.1    Takahashi, S.2    Shioiri, T.3
  • 35
    • 0029004598 scopus 로고
    • Lateralized abnormality of high energy phosphate metabolism in the frontal lobes of patients with bipolar disorder detected by phase-encoded 31P-MRS
    • Kato T, Shioiri T, Murashita J, et al. Lateralized abnormality of high energy phosphate metabolism in the frontal lobes of patients with bipolar disorder detected by phase-encoded 31P-MRS. Psychol Med. 1995;25:557-566.
    • (1995) Psychol Med , vol.25 , pp. 557-566
    • Kato, T.1    Shioiri, T.2    Murashita, J.3
  • 36
    • 0032977724 scopus 로고    scopus 로고
    • Quantitative proton magnetic resonance spectroscopy of the bilateral frontal lobes in patients with bipolar disorder
    • Hamakawa H, Kato T, Shioiri T, et al. Quantitative proton magnetic resonance spectroscopy of the bilateral frontal lobes in patients with bipolar disorder. Psychol Med. 1999;29:639-644.
    • (1999) Psychol Med , vol.29 , pp. 639-644
    • Hamakawa, H.1    Kato, T.2    Shioiri, T.3
  • 37
    • 0029036333 scopus 로고
    • Abnormal frontal lobe phosphorous metabolism in bipolar disorder
    • Deicken RF, Fein G, Weiner MW. Abnormal frontal lobe phosphorous metabolism in bipolar disorder. Am J Psychiatry. 1995;152:915-918.
    • (1995) Am J Psychiatry , vol.152 , pp. 915-918
    • Deicken, R.F.1    Fein, G.2    Weiner, M.W.3
  • 38
    • 0032217116 scopus 로고    scopus 로고
    • 31P magnetic resonance spectroscopy in the frontal lobe of major depressed patients
    • Volz HP, Rzanny R, Riehemann S, et al. 31P magnetic resonance spectroscopy in the frontal lobe of major depressed patients. Eur Arch Psychiatry Clin Neurosci. 1998;248:289-295.
    • (1998) Eur Arch Psychiatry Clin Neurosci , vol.248 , pp. 289-295
    • Volz, H.P.1    Rzanny, R.2    Riehemann, S.3
  • 39
    • 0031016616 scopus 로고    scopus 로고
    • Lower levels of nucleoside triphosphate in the basal ganglia of depressed subjects: A phosphorous-31 magnetic resonance spectroscopy study
    • Moore CM, Christensen JD, Lafer B, et al. Lower levels of nucleoside triphosphate in the basal ganglia of depressed subjects: a phosphorous-31 magnetic resonance spectroscopy study. Am J Psychiatry. 1997;154:116-118.
    • (1997) Am J Psychiatry , vol.154 , pp. 116-118
    • Moore, C.M.1    Christensen, J.D.2    Lafer, B.3
  • 40
    • 0027339579 scopus 로고
    • Alterations in brain phosphorous metabolism in bipolar disorder detected by in vivo 31P and 7Li magnetic resonance spectroscopy
    • Kato T, Takahashi S, Shioiri T, et al. Alterations in brain phosphorous metabolism in bipolar disorder detected by in vivo 31P and 7Li magnetic resonance spectroscopy. J Affect Disord. 1993;27:53-59.
    • (1993) J Affect Disord , vol.27 , pp. 53-59
    • Kato, T.1    Takahashi, S.2    Shioiri, T.3
  • 41
    • 1042276837 scopus 로고    scopus 로고
    • Reduced intracellular pH in the basal ganglia and whole brain measured by 31P-MRS in bipolar disorder
    • Hamakawa H, Murashita J, Yamada N, et al. Reduced intracellular pH in the basal ganglia and whole brain measured by 31P-MRS in bipolar disorder. Psychiatry Clin Neurosci. 2004;58:82-88.
    • (2004) Psychiatry Clin Neurosci , vol.58 , pp. 82-88
    • Hamakawa, H.1    Murashita, J.2    Yamada, N.3
  • 42
    • 0032443669 scopus 로고    scopus 로고
    • Decreased brain intracellular pH measured by 31P-MRS in bipolar disorder: A confirmation in drug-free patients and correlation with white matter hyperintensity
    • Kato T, Murashita J, Kamiya A, et al. Decreased brain intracellular pH measured by 31P-MRS in bipolar disorder: a confirmation in drug-free patients and correlation with white matter hyperintensity. Eur Arch Psychiatry Clin Neurosci. 1998;248:301-306.
    • (1998) Eur Arch Psychiatry Clin Neurosci , vol.248 , pp. 301-306
    • Kato, T.1    Murashita, J.2    Kamiya, A.3
  • 43
    • 33745463205 scopus 로고    scopus 로고
    • Down regulation in components of mitochondrial electron transport chain in post-mortem frontal cortex from subjects with bipolar disorder
    • Sun X, Wang JF, Tseng M, et al. Down regulation in components of mitochondrial electron transport chain in post-mortem frontal cortex from subjects with bipolar disorder. J Psychiatry Neurosci. 2006;31:189-196.
    • (2006) J Psychiatry Neurosci , vol.31 , pp. 189-196
    • Sun, X.1    Wang, J.F.2    Tseng, M.3
  • 44
    • 2442454784 scopus 로고    scopus 로고
    • Brain metabolic alterations in medication-free patients with bipolar disorder
    • Dager SR, Friedman SD, Parow A, et al. Brain metabolic alterations in medication-free patients with bipolar disorder. Arch Gen Psychiatry. 2004;61:450-458.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 450-458
    • Dager, S.R.1    Friedman, S.D.2    Parow, A.3
  • 45
    • 0032532302 scopus 로고    scopus 로고
    • Energy requirements for two aspects of phospholipid metabolism in mammalian brain
    • Purdon AD, Rapoport SI. Energy requirements for two aspects of phospholipid metabolism in mammalian brain. Biochem J. 1998;335:313-318.
    • (1998) Biochem J , vol.335 , pp. 313-318
    • Purdon, A.D.1    Rapoport, S.I.2
  • 46
    • 0028958244 scopus 로고
    • Decreased temporal lobe phosphomonoesters in bipolar disorder
    • Deicken RF, Weiner MW, Fein G. Decreased temporal lobe phosphomonoesters in bipolar disorder. J Affect Disord. 1995;33:195-199.
    • (1995) J Affect Disord , vol.33 , pp. 195-199
    • Deicken, R.F.1    Weiner, M.W.2    Fein, G.3
  • 47
    • 0036514755 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy: Neurochemistry and treatment effects in affective disorders
    • Moore GJ, Galloway MP. Magnetic resonance spectroscopy: neurochemistry and treatment effects in affective disorders. Psychopharmacol Bull. 2002;36:5-23.
    • (2002) Psychopharmacol Bull , vol.36 , pp. 5-23
    • Moore, G.J.1    Galloway, M.P.2
  • 48
    • 0031935232 scopus 로고    scopus 로고
    • Quantitative proton magnetic resonance spectroscopy of the basal ganglia in patients with affective disorders
    • Hamakawa H, Kato T, Murashita J, et al. Quantitative proton magnetic resonance spectroscopy of the basal ganglia in patients with affective disorders. Eur Arch Psychiatry Clin Neurosci. 1998;248:53-58.
    • (1998) Eur Arch Psychiatry Clin Neurosci , vol.248 , pp. 53-58
    • Hamakawa, H.1    Kato, T.2    Murashita, J.3
  • 49
    • 0041880362 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents
    • Davanzo P, Yue K, Thomas MA, et al. Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents. Am J Psychiatry. 2003;160:1442-1452.
    • (2003) Am J Psychiatry , vol.160 , pp. 1442-1452
    • Davanzo, P.1    Yue, K.2    Thomas, M.A.3
  • 50
    • 0026665540 scopus 로고
    • Proton magnetic resonance spectroscopy of the brain in schizophrenic and affective patients
    • Sharma R, Venkatasubramanian PN, Barany M, et al. Proton magnetic resonance spectroscopy of the brain in schizophrenic and affective patients. Schizophr Res. 1992;8:43-49.
    • (1992) Schizophr Res , vol.8 , pp. 43-49
    • Sharma, R.1    Venkatasubramanian, P.N.2    Barany, M.3
  • 51
    • 0035972848 scopus 로고    scopus 로고
    • 31P nuclear magnetic resonance spectroscopy findings in bipolar illness: A meta-analysis
    • Yildiz A, Sachs GS, Dorer DJ, et al. 31P nuclear magnetic resonance spectroscopy findings in bipolar illness: a meta-analysis. Psychiatry Res. 2001;106:181-191.
    • (2001) Psychiatry Res , vol.106 , pp. 181-191
    • Yildiz, A.1    Sachs, G.S.2    Dorer, D.J.3
  • 52
    • 14844325795 scopus 로고    scopus 로고
    • Aberrant intracellular calcium signaling in olfactory neurons from patients with bipolar disorder
    • Hahn CG, Gomez G, Restrepo D, et al. Aberrant intracellular calcium signaling in olfactory neurons from patients with bipolar disorder. Am J Psychiatry. 2005;162:616-618.
    • (2005) Am J Psychiatry , vol.162 , pp. 616-618
    • Hahn, C.G.1    Gomez, G.2    Restrepo, D.3
  • 53
    • 0030997903 scopus 로고    scopus 로고
    • High intracellular calcium concentrations in transformed lymphoblasts from subjects with bipolar I disorder
    • Emamghoreishi M, Schlichter L, Li PP, et al. High intracellular calcium concentrations in transformed lymphoblasts from subjects with bipolar I disorder. Am J Psychiatry. 1997;154:976-982.
    • (1997) Am J Psychiatry , vol.154 , pp. 976-982
    • Emamghoreishi, M.1    Schlichter, L.2    Li, P.P.3
  • 54
    • 0028281236 scopus 로고
    • Intracellular calcium signalling in peripheral cells of patients with bipolar affective disorder
    • Dubovsky SL, Thomas M, Hijazi A, et al. Intracellular calcium signalling in peripheral cells of patients with bipolar affective disorder. Eur Arch Psychiatry Clin Neurosci. 1994;243:229-234.
    • (1994) Eur Arch Psychiatry Clin Neurosci , vol.243 , pp. 229-234
    • Dubovsky, S.L.1    Thomas, M.2    Hijazi, A.3
  • 55
    • 0034750695 scopus 로고    scopus 로고
    • Altered IMPA2 gene expression and calcium homeostasis in bipolar disorder
    • Yoon IS, Li PP, Siu KP, et al. Altered IMPA2 gene expression and calcium homeostasis in bipolar disorder. Mol Psychiatry. 2001;6:678-683.
    • (2001) Mol Psychiatry , vol.6 , pp. 678-683
    • Yoon, I.S.1    Li, P.P.2    Siu, K.P.3
  • 56
    • 0030692027 scopus 로고    scopus 로고
    • Increased levels of a mitochondrial DNA deletion in the brain of patients with bipolar disorder
    • Kato T, Stine OC, McMahon FJ, et al. Increased levels of a mitochondrial DNA deletion in the brain of patients with bipolar disorder. Biol Psychiatry. 1997;42:871-875.
    • (1997) Biol Psychiatry , vol.42 , pp. 871-875
    • Kato, T.1    Stine, O.C.2    McMahon, F.J.3
  • 57
    • 0035109413 scopus 로고    scopus 로고
    • Mitochondrial DNA polymorphisms in bipolar disorder
    • Kato T, Kunugi H, Nanko S, et al. Mitochondrial DNA polymorphisms in bipolar disorder. J Affect Disord. 2001;62:151-164.
    • (2001) J Affect Disord , vol.62 , pp. 151-164
    • Kato, T.1    Kunugi, H.2    Nanko, S.3
  • 58
    • 0034599970 scopus 로고    scopus 로고
    • Association of bipolar disorder with the 5178 polymorphism in mitochondrial DNA
    • Kato T, Kunugi H, Nanko S, et al. Association of bipolar disorder with the 5178 polymorphism in mitochondrial DNA. Am J Med Genet. 2000;96:182-186.
    • (2000) Am J Med Genet , vol.96 , pp. 182-186
    • Kato, T.1    Kunugi, H.2    Nanko, S.3
  • 59
    • 0032539447 scopus 로고    scopus 로고
    • Mitochondrial genotype associated with longevity
    • Tanaka M, Gong J-S, Zhang J, et al. Mitochondrial genotype associated with longevity. Lancet. 1998;351:185-186.
    • (1998) Lancet , vol.351 , pp. 185-186
    • Tanaka, M.1    Gong, J.-S.2    Zhang, J.3
  • 60
    • 24744442376 scopus 로고    scopus 로고
    • Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women
    • Canter JA, Kallianpur AR, Parl FF, et al. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res. 2005;65:8028-8033.
    • (2005) Cancer Res , vol.65 , pp. 8028-8033
    • Canter, J.A.1    Kallianpur, A.R.2    Parl, F.F.3
  • 61
    • 7944219894 scopus 로고    scopus 로고
    • Mitochondrial DNA 3644T C mutation associated with bipolar disorder
    • Munakata K, Tanaka M, Mori K, et al. Mitochondrial DNA 3644T C mutation associated with bipolar disorder. Genomics. 2004;84:1041-1050.
    • (2004) Genomics , vol.84 , pp. 1041-1050
    • Munakata, K.1    Tanaka, M.2    Mori, K.3
  • 62
    • 4644245608 scopus 로고    scopus 로고
    • Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder in Japanese and the National Institute of Mental Health pedigrees
    • Washizuka S, Iwamoto K, Kazuno AA, et al. Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder in Japanese and the National Institute of Mental Health pedigrees. Biol Psychiatry. 2004;56:483-489.
    • (2004) Biol Psychiatry , vol.56 , pp. 483-489
    • Washizuka, S.1    Iwamoto, K.2    Kazuno, A.A.3
  • 63
    • 0042322709 scopus 로고    scopus 로고
    • Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder
    • Washizuka S, Kakiuchi C, Mori K, et al. Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2003;120:72-78.
    • (2003) Am J Med Genet B Neuropsychiatr Genet , vol.120 , pp. 72-78
    • Washizuka, S.1    Kakiuchi, C.2    Mori, K.3
  • 64
    • 0029024362 scopus 로고
    • Molecular cloning and characterization of the active human mitochondrial NADH: Ubiquinone oxidoreductase 24-kDa gene (NDUFV2) and its pseudogene
    • de Coo R, Buddiger P, Smeets H, et al. Molecular cloning and characterization of the active human mitochondrial NADH: ubiquinone oxidoreductase 24-kDa gene (NDUFV2) and its pseudogene. Genomics. 1995;26:461-466.
    • (1995) Genomics , vol.26 , pp. 461-466
    • de Coo, R.1    Buddiger, P.2    Smeets, H.3
  • 65
    • 13044281675 scopus 로고    scopus 로고
    • A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2
    • Detera-Wadleigh SD, Badner JA, Berrettini WH, et al. A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc Natl Acad Sci USA. 1999;96:5604-5609.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5604-5609
    • Detera-Wadleigh, S.D.1    Badner, J.A.2    Berrettini, W.H.3
  • 66
    • 0031423325 scopus 로고    scopus 로고
    • An integrated physical map of 18p11.2: A susceptibility region for bipolar disorder
    • Esterling LE, Cox Matise T, Sanders AR, et al. An integrated physical map of 18p11.2: a susceptibility region for bipolar disorder. Mol Psychiatry. 1997;2:501-504.
    • (1997) Mol Psychiatry , vol.2 , pp. 501-504
    • Esterling, L.E.1    Cox Matise, T.2    Sanders, A.R.3
  • 67
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell B. Reactive oxygen species and the central nervous system. J Neurochem. 1992;59:1609-1623.
    • (1992) J Neurochem , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 68
    • 1542366428 scopus 로고    scopus 로고
    • Molecular evidence for mitochondrial dysfunction in bipolar disorder
    • Konradi C, Eaton M, MacDonald ML, et al. Molecular evidence for mitochondrial dysfunction in bipolar disorder. Arch Gen Psychiatry. 2004;61:300-308.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 300-308
    • Konradi, C.1    Eaton, M.2    MacDonald, M.L.3
  • 69
    • 12744278205 scopus 로고    scopus 로고
    • Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis
    • Iwamoto K, Bundo M, Kato T. Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis. Hum Mol Genet. 2005;14:241-253.
    • (2005) Hum Mol Genet , vol.14 , pp. 241-253
    • Iwamoto, K.1    Bundo, M.2    Kato, T.3
  • 70
    • 33644622470 scopus 로고    scopus 로고
    • Genome-wide linkage scan in a large bipolar disorder sample from the National Institute of Mental Health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder
    • Cheng R, Juo SH, Loth JE, et al. Genome-wide linkage scan in a large bipolar disorder sample from the National Institute of Mental Health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder. Mol Psychiatry. 2006;11:252-260.
    • (2006) Mol Psychiatry , vol.11 , pp. 252-260
    • Cheng, R.1    Juo, S.H.2    Loth, J.E.3
  • 71
    • 0035179492 scopus 로고    scopus 로고
    • Gene expression differences in bipolar disorder revealed by cDNA array analysis of post-mortem frontal cortex
    • Bezchlibnyk YB, Wang JF, McQueen GM, et al. Gene expression differences in bipolar disorder revealed by cDNA array analysis of post-mortem frontal cortex. J Neurochem. 2001;79:826-834.
    • (2001) J Neurochem , vol.79 , pp. 826-834
    • Bezchlibnyk, Y.B.1    Wang, J.F.2    McQueen, G.M.3
  • 72
    • 33644622093 scopus 로고    scopus 로고
    • The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia
    • Benes FM, Matzilevich D, Burke RE, et al. The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia. Mol Psychiatry. 2006;11:241-251.
    • (2006) Mol Psychiatry , vol.11 , pp. 241-251
    • Benes, F.M.1    Matzilevich, D.2    Burke, R.E.3
  • 73
    • 0036096195 scopus 로고    scopus 로고
    • Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder
    • Kuloglu M, Ustundag B, Atmaca M, et al. Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder. Cell Biochem Funct. 2002;20:171-175.
    • (2002) Cell Biochem Funct , vol.20 , pp. 171-175
    • Kuloglu, M.1    Ustundag, B.2    Atmaca, M.3
  • 74
    • 0344628598 scopus 로고    scopus 로고
    • Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients
    • Ranjekar PK, Hinge A, Hegde MV, et al. Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients. Psychiatry Res. 2003;121:109-122.
    • (2003) Psychiatry Res , vol.121 , pp. 109-122
    • Ranjekar, P.K.1    Hinge, A.2    Hegde, M.V.3
  • 75
    • 1542299043 scopus 로고    scopus 로고
    • Antioxidant enzyme activities and oxidative stress in affective disorders
    • Ozcan ME, Gulec M, Ozerol E, et al. Antioxidant enzyme activities and oxidative stress in affective disorders. Int Clin Psychopharmacol. 2004;19:89-95.
    • (2004) Int Clin Psychopharmacol , vol.19 , pp. 89-95
    • Ozcan, M.E.1    Gulec, M.2    Ozerol, E.3
  • 76
    • 33845866091 scopus 로고    scopus 로고
    • Increased oxidative stress and DNA damage in bipolar disorder: A twin-case report
    • Frey BN, Andreazza AC, Kunz M, et al. Increased oxidative stress and DNA damage in bipolar disorder: a twin-case report. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31:283-285.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 283-285
    • Frey, B.N.1    Andreazza, A.C.2    Kunz, M.3
  • 77
    • 0037474040 scopus 로고    scopus 로고
    • Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cells
    • Wang JF, Azzam JE, Young LT. Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cells. Neuroscience. 2003;116:485-489.
    • (2003) Neuroscience , vol.116 , pp. 485-489
    • Wang, J.F.1    Azzam, J.E.2    Young, L.T.3
  • 78
    • 29044447411 scopus 로고    scopus 로고
    • Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells
    • Shao L, Young LT, Wang JF. Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells. Biol Psychiatry. 2005;58:879-884.
    • (2005) Biol Psychiatry , vol.58 , pp. 879-884
    • Shao, L.1    Young, L.T.2    Wang, J.F.3
  • 79
    • 33646863671 scopus 로고    scopus 로고
    • Cytoprotection by lithium and valproate varies between cell types and cellular stresses
    • Lai JS, Zhao C, Warsh JJ, et al. Cytoprotection by lithium and valproate varies between cell types and cellular stresses. Eur J Pharmacol. 2006;539:18-26.
    • (2006) Eur J Pharmacol , vol.539 , pp. 18-26
    • Lai, J.S.1    Zhao, C.2    Warsh, J.J.3
  • 80
    • 17844403720 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress
    • King TD, Jope RS. Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress. Neuroreport. 2005;16:597-601.
    • (2005) Neuroreport , vol.16 , pp. 597-601
    • King, T.D.1    Jope, R.S.2
  • 81
    • 33846303907 scopus 로고    scopus 로고
    • Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate
    • Cui J, Shao L, Young LT, et al. Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate. Neuroscience. 2007;144:1447-1453.
    • (2007) Neuroscience , vol.144 , pp. 1447-1453
    • Cui, J.1    Shao, L.2    Young, L.T.3
  • 82
    • 1642373092 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase 3 beta is involved in the resistance to oxidative stress in neuronal HT22 cells
    • Schafer M, Goodenough S, Moosmann B, et al. Inhibition of glycogen synthase kinase 3 beta is involved in the resistance to oxidative stress in neuronal HT22 cells. Brain Res. 2004;1005:84-89.
    • (2004) Brain Res , vol.1005 , pp. 84-89
    • Schafer, M.1    Goodenough, S.2    Moosmann, B.3
  • 83
    • 0037424245 scopus 로고    scopus 로고
    • Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production
    • Li N, Ragheb K, Lawler G, et al. Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem. 2003;278:8516-8525.
    • (2003) J Biol Chem , vol.278 , pp. 8516-8525
    • Li, N.1    Ragheb, K.2    Lawler, G.3
  • 84
    • 0043173819 scopus 로고    scopus 로고
    • Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide
    • Wei Z, Bai O, Richardson JS, et al. Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide. J Neurosci Res. 2003;73:364-368.
    • (2003) J Neurosci Res , vol.73 , pp. 364-368
    • Wei, Z.1    Bai, O.2    Richardson, J.S.3
  • 85
    • 24744433317 scopus 로고    scopus 로고
    • Olanzapine and quetiapine protect PC12 cells from beta-amyloid peptide(25-35)-induced oxidative stress and the ensuing apoptosis
    • Wang H, Xu H, Dyck LE, et al. Olanzapine and quetiapine protect PC12 cells from beta-amyloid peptide(25-35)-induced oxidative stress and the ensuing apoptosis. J Neurosci Res. 2005;81:572-580.
    • (2005) J Neurosci Res , vol.81 , pp. 572-580
    • Wang, H.1    Xu, H.2    Dyck, L.E.3
  • 86
    • 33749370570 scopus 로고    scopus 로고
    • Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania
    • Frey BN, Valvassori SS, Reus GZ, et al. Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania. J Psychiatry Neurosci. 2006;31:326-332.
    • (2006) J Psychiatry Neurosci , vol.31 , pp. 326-332
    • Frey, B.N.1    Valvassori, S.S.2    Reus, G.Z.3
  • 87
    • 1642390910 scopus 로고    scopus 로고
    • Glutathione S-transferase is a novel target for mood stabilizing drugs in primary cultured neurons
    • Wang JF, Shao L, Sun X, et al. Glutathione S-transferase is a novel target for mood stabilizing drugs in primary cultured neurons. J Neurochem. 2004;88(6):1477-1484.
    • (2004) J Neurochem , vol.88 , Issue.6 , pp. 1477-1484
    • Wang, J.F.1    Shao, L.2    Sun, X.3
  • 88
    • 85069300538 scopus 로고    scopus 로고
    • The effect of mood stabilizing drug lithium on expression and activity of glutathione s-transferase isoenzymes in primary cultured rat cerebral cortical cells
    • Wang JF, Shao L, Cui J, et al. The effect of mood stabilizing drug lithium on expression and activity of glutathione s-transferase isoenzymes in primary cultured rat cerebral cortical cells. Free Radical Research. 2006;40:S159.
    • (2006) Free Radical Research , vol.40
    • Wang, J.F.1    Shao, L.2    Cui, J.3
  • 89
    • 1542619261 scopus 로고    scopus 로고
    • Antioxidant role of glutathione S-transferases: Protection against oxidant toxicity and regulation of stress-mediated apoptosis
    • Sharma R, Yang Y, Sharma A, et al. Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis. Antioxid Redox Signal. 2004;6:289-300.
    • (2004) Antioxid Redox Signal , vol.6 , pp. 289-300
    • Sharma, R.1    Yang, Y.2    Sharma, A.3
  • 90
    • 0023117321 scopus 로고
    • Mechanism of lithium action: In vivo and in vitro effects of alkali metals on brain superoxide dismutase
    • Shukla GS. Mechanism of lithium action: in vivo and in vitro effects of alkali metals on brain superoxide dismutase. Pharmacol Biochem Behav. 1987;26:235-240.
    • (1987) Pharmacol Biochem Behav , vol.26 , pp. 235-240
    • Shukla, G.S.1
  • 91
    • 33748589993 scopus 로고    scopus 로고
    • Chronic lithium treatment has antioxidant properties but does not prevent oxidative damage induced by chronic variate stress
    • de Vasconcellos AP, Nieto FB, Crema LM, et al. Chronic lithium treatment has antioxidant properties but does not prevent oxidative damage induced by chronic variate stress. Neurochem Res. 2006;31:1141-1151.
    • (2006) Neurochem Res , vol.31 , pp. 1141-1151
    • de Vasconcellos, A.P.1    Nieto, F.B.2    Crema, L.M.3
  • 92
    • 0033118431 scopus 로고    scopus 로고
    • Differential effects of olanzapine on the gene expression of superoxide dismutase and the low affinity nerve growth factor receptor
    • Li XM, Chlan-Fourney J, Juorio AV, et al. Differential effects of olanzapine on the gene expression of superoxide dismutase and the low affinity nerve growth factor receptor. J Neurosci Res. 1999;56:72-75.
    • (1999) J Neurosci Res , vol.56 , pp. 72-75
    • Li, X.M.1    Chlan-Fourney, J.2    Juorio, A.V.3
  • 93
    • 0034930671 scopus 로고    scopus 로고
    • Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system
    • Reiter RJ, Acuna-Castroviejo D, Tan DX, et al. Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system. Ann N Y Acad Sci. 2001;939:200-215.
    • (2001) Ann N Y Acad Sci , vol.939 , pp. 200-215
    • Reiter, R.J.1    Acuna-Castroviejo, D.2    Tan, D.X.3
  • 94
    • 4544345529 scopus 로고    scopus 로고
    • Free radicals in cell biology
    • Djordjevic VB. Free radicals in cell biology. Int Rev Cytol. 2004;237:57-89.
    • (2004) Int Rev Cytol , vol.237 , pp. 57-89
    • Djordjevic, V.B.1
  • 95
    • 0034307061 scopus 로고    scopus 로고
    • Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus
    • Chen B, Wang JF, Young LT. Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus. Biol Psychiatry. 2000;48:658-664.
    • (2000) Biol Psychiatry , vol.48 , pp. 658-664
    • Chen, B.1    Wang, J.F.2    Young, L.T.3
  • 96
    • 0033050865 scopus 로고    scopus 로고
    • Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78
    • Wang JF, Bown C, Young LT. Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78. Mol Pharmacol. 1999;55:521-527.
    • (1999) Mol Pharmacol , vol.55 , pp. 521-527
    • Wang, J.F.1    Bown, C.2    Young, L.T.3
  • 97
    • 32044462724 scopus 로고    scopus 로고
    • Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells
    • Shao L, Sun X, Xu L, et al. Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells. Life Sci. 2006;78:1317-1323.
    • (2006) Life Sci , vol.78 , pp. 1317-1323
    • Shao, L.1    Sun, X.2    Xu, L.3
  • 98
    • 16344382201 scopus 로고    scopus 로고
    • Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: Roles of intracellular calcium, GRP78 and Bcl-2
    • Hiroi T, Wei H, Hough C, et al. Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2. Pharmacogenomics J. 2005;5:102-111.
    • (2005) Pharmacogenomics J , vol.5 , pp. 102-111
    • Hiroi, T.1    Wei, H.2    Hough, C.3
  • 99
    • 0035423875 scopus 로고    scopus 로고
    • The glucose-regulated proteins: Stress induction and clinical applications
    • Lee AS. The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci. 2001;26:504-510.
    • (2001) Trends Biochem Sci , vol.26 , pp. 504-510
    • Lee, A.S.1
  • 100
    • 0033015485 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: Suppression of oxidative stress and stabilization of calcium homeostasis
    • Yu Z, Luo H, Fu W, et al. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp Neurol. 1999;155:302-314.
    • (1999) Exp Neurol , vol.155 , pp. 302-314
    • Yu, Z.1    Luo, H.2    Fu, W.3
  • 101
    • 0027957793 scopus 로고
    • A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes CA2+ binding proteins and member of the thioredoxin superfamily
    • Nigam SK, Goldberg AL, Ho S, et al. A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes CA2+ binding proteins and member of the thioredoxin superfamily. J Biol Chem. 1994;269:1744-1749.
    • (1994) J Biol Chem , vol.269 , pp. 1744-1749
    • Nigam, S.K.1    Goldberg, A.L.2    Ho, S.3
  • 102
    • 0033525538 scopus 로고    scopus 로고
    • Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity
    • Chen RW, Chuang DM. Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity. J Biol Chem. 1999;274:6039-6042.
    • (1999) J Biol Chem , vol.274 , pp. 6039-6042
    • Chen, R.W.1    Chuang, D.M.2
  • 103
    • 0032956630 scopus 로고    scopus 로고
    • The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • Chen G, Zeng WZ, Yuan PX, et al. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J Neurochem. 1999;72:879-882.
    • (1999) J Neurochem , vol.72 , pp. 879-882
    • Chen, G.1    Zeng, W.Z.2    Yuan, P.X.3
  • 104
    • 0035827095 scopus 로고    scopus 로고
    • Regional expression of Bcl-2 mRNA and mitochondrial cytochrome c release after experimental brain injury in the rat
    • Dong GX, Singh DK, Dendle P, et al. Regional expression of Bcl-2 mRNA and mitochondrial cytochrome c release after experimental brain injury in the rat. Brain Res. 2001;903:45-52.
    • (2001) Brain Res , vol.903 , pp. 45-52
    • Dong, G.X.1    Singh, D.K.2    Dendle, P.3
  • 105
    • 0033774468 scopus 로고    scopus 로고
    • Bcl-2 prevents mitochondrial permeability transition and cytochrome c release via maintenance of reduced pyridine nucleotides
    • Kowaltowski AJ, Vercesi AE, Fiskum G. Bcl-2 prevents mitochondrial permeability transition and cytochrome c release via maintenance of reduced pyridine nucleotides. Cell Death Differ. 2000;7:903-910.
    • (2000) Cell Death Differ , vol.7 , pp. 903-910
    • Kowaltowski, A.J.1    Vercesi, A.E.2    Fiskum, G.3
  • 106
    • 0037314543 scopus 로고    scopus 로고
    • Regulation of c-Jun N-terminal kinase, p38 kinase and AP-1 DNA binding in cultured brain neurons: Roles in glutamate excitotoxicity and lithium neuroprotection
    • Chen RW, Qin ZH, Ren M, et al. Regulation of c-Jun N-terminal kinase, p38 kinase and AP-1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection. J Neurochem. 2003;84:566-575.
    • (2003) J Neurochem , vol.84 , pp. 566-575
    • Chen, R.W.1    Qin, Z.H.2    Ren, M.3
  • 107
    • 0242475154 scopus 로고    scopus 로고
    • Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau
    • Ghribi O, Prammonjago P, Herman MM, et al. Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau. Brain Res Mol Brain Res. 2003;119:201-206.
    • (2003) Brain Res Mol Brain Res , vol.119 , pp. 201-206
    • Ghribi, O.1    Prammonjago, P.2    Herman, M.M.3
  • 108
    • 33745205104 scopus 로고    scopus 로고
    • Melatonin: Nature most versatile biological signal?
    • Pandi-Perumal SR, Srinivasan V, Maestroni GJ, et al. Melatonin: nature most versatile biological signal? FEBS J. 2006;273:2813-2838.
    • (2006) FEBS J , vol.273 , pp. 2813-2838
    • Pandi-Perumal, S.R.1    Srinivasan, V.2    Maestroni, G.J.3
  • 109
    • 29544435842 scopus 로고    scopus 로고
    • Gao K, Calabrese JR. Newer treatment studies for bipolar depression. Bipolar Disord. 2005;7:13-23. Can J Psychiatry 2007;52:763-771
    • Gao K, Calabrese JR. Newer treatment studies for bipolar depression. Bipolar Disord. 2005;7:13-23. Can J Psychiatry 2007;52:763-771


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.