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Volumn 19, Issue 2, 2008, Pages 118-128

Apoptosis induced by oxidized lipids is associated with up-regulation of p66Shc in intestinal Caco-2 cells: protective effects of phenolic compounds

Author keywords

Apoptosis; Caco 2; Glutathione; Oxidized lipids; oxLDL; p66Shc; Polyphenols

Indexed keywords

CATALASE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYDROGEN PEROXIDE; LIPID; LOW DENSITY LIPOPROTEIN; NUCLEAR PROTEIN; OLIVE OIL; OXYGEN; PHENOL DERIVATIVE; POLYPHENOL DERIVATIVE; PROTEIN P66SHC; PROTOCATECHUIC ACID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TYROSOL; UNCLASSIFIED DRUG;

EID: 37549048966     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2007.01.010     Document Type: Article
Times cited : (39)

References (47)
  • 1
    • 0020633994 scopus 로고
    • Role of oxygen-derived free radical in digestive tract diseases
    • Parks D.A., Bulkley G.B., and Granger D.N. Role of oxygen-derived free radical in digestive tract diseases. Surgery 94 (1983) 415-422
    • (1983) Surgery , vol.94 , pp. 415-422
    • Parks, D.A.1    Bulkley, G.B.2    Granger, D.N.3
  • 2
    • 0027959253 scopus 로고
    • Oxidants and free radicals in inflammatory bowel disease
    • Grisham M.B. Oxidants and free radicals in inflammatory bowel disease. Lancet 344 (1994) 859-861
    • (1994) Lancet , vol.344 , pp. 859-861
    • Grisham, M.B.1
  • 3
    • 0000092645 scopus 로고    scopus 로고
    • Molecular and cellular responses to oxidative stress and changes in oxidation-reduction imbalance in the intestine
    • Aw T.Y. Molecular and cellular responses to oxidative stress and changes in oxidation-reduction imbalance in the intestine. Am J Clin Nutr 70 (1999) 557-565
    • (1999) Am J Clin Nutr , vol.70 , pp. 557-565
    • Aw, T.Y.1
  • 5
    • 0036182939 scopus 로고    scopus 로고
    • Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for cardiovascular health
    • Kris-Etherton P.M., and Keen C.L. Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for cardiovascular health. Curr Opin Lipidol 13 (2002) 41-49
    • (2002) Curr Opin Lipidol , vol.13 , pp. 41-49
    • Kris-Etherton, P.M.1    Keen, C.L.2
  • 6
    • 0032499596 scopus 로고    scopus 로고
    • Free radical-scavenging properties of olive oil polyphenols
    • Visioli F., Bellomo G., and Galli C. Free radical-scavenging properties of olive oil polyphenols. Biochem Biophys Res Comm 247 (1998) 60-64
    • (1998) Biochem Biophys Res Comm , vol.247 , pp. 60-64
    • Visioli, F.1    Bellomo, G.2    Galli, C.3
  • 7
    • 0033021259 scopus 로고    scopus 로고
    • Dietary flavonoids protect human colonocyte DNA from oxidative attack in vitro
    • Duthie S.J., and Dobson V.L. Dietary flavonoids protect human colonocyte DNA from oxidative attack in vitro. Eur J Nutr 38 (1999) 28-34
    • (1999) Eur J Nutr , vol.38 , pp. 28-34
    • Duthie, S.J.1    Dobson, V.L.2
  • 8
    • 14744287885 scopus 로고    scopus 로고
    • Polyphenols and prevention of cardiovascular diseases
    • Manach C., Mazur A., and Scalbert A. Polyphenols and prevention of cardiovascular diseases. Curr Opin Lipidol 16 (2005) 77-84
    • (2005) Curr Opin Lipidol , vol.16 , pp. 77-84
    • Manach, C.1    Mazur, A.2    Scalbert, A.3
  • 10
    • 0031408813 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinases by green tea polyphenols: potential signalling pathways in the regulation of antioxidant-responsive element-mediated phase II enzyme gene expression
    • Yu R., Jiao J.J., Duh J.L., Gudehithlu K., Tan T.H., and Kong A.N. Activation of mitogen-activated protein kinases by green tea polyphenols: potential signalling pathways in the regulation of antioxidant-responsive element-mediated phase II enzyme gene expression. Carcinogenesis 18 (1997) 451-456
    • (1997) Carcinogenesis , vol.18 , pp. 451-456
    • Yu, R.1    Jiao, J.J.2    Duh, J.L.3    Gudehithlu, K.4    Tan, T.H.5    Kong, A.N.6
  • 11
    • 13844298231 scopus 로고    scopus 로고
    • Health promotion by flavonoids tocopherols, tocotrienols and other phenols: direct or indirect effects? Antioxidant or not?
    • Halliwell B., Rafter J., and Jenner A. Health promotion by flavonoids tocopherols, tocotrienols and other phenols: direct or indirect effects? Antioxidant or not?. Am J Clin 81 Suppl (2005) 268S-276S
    • (2005) Am J Clin , vol.81 , Issue.SUPPL
    • Halliwell, B.1    Rafter, J.2    Jenner, A.3
  • 12
    • 0033805296 scopus 로고    scopus 로고
    • Triggering and modulation of apoptosis by oxidative stress
    • Chandra J., Samali A., and Orrenius S. Triggering and modulation of apoptosis by oxidative stress. Free Radic Biol Med 29 (2000) 323-333
    • (2000) Free Radic Biol Med , vol.29 , pp. 323-333
    • Chandra, J.1    Samali, A.2    Orrenius, S.3
  • 13
    • 0032930114 scopus 로고    scopus 로고
    • Lp (a) and LDL induce apoptosis in human endothelial cells and in rabbit aorta: role of oxidative stress
    • Galle J., Schneider R., Heinloth A., Wanner C., Galle P.R., Conzelmann E., et al. Lp (a) and LDL induce apoptosis in human endothelial cells and in rabbit aorta: role of oxidative stress. Kidney Int 55 (1999) 1450-1461
    • (1999) Kidney Int , vol.55 , pp. 1450-1461
    • Galle, J.1    Schneider, R.2    Heinloth, A.3    Wanner, C.4    Galle, P.R.5    Conzelmann, E.6
  • 14
    • 0033012280 scopus 로고    scopus 로고
    • Tyrosol, the major olive oil biophenol, protects against oxidized-LDL-induced injury in Caco-2 cells
    • Giovannini C., Straface E., Modesti D., Coni E., Cantafora A., De Vincenzi M., et al. Tyrosol, the major olive oil biophenol, protects against oxidized-LDL-induced injury in Caco-2 cells. J Nutr 129 (1999) 1269-1277
    • (1999) J Nutr , vol.129 , pp. 1269-1277
    • Giovannini, C.1    Straface, E.2    Modesti, D.3    Coni, E.4    Cantafora, A.5    De Vincenzi, M.6
  • 15
    • 0037125237 scopus 로고    scopus 로고
    • Mitochondria hyperpolarization is an early event in oxidized low density lipoprotein-induced apoptosis in Caco-2 cells
    • Giovannini C., Matarrese P., Scazzocchio B., Sanchez M., Masella R., and Malorni W. Mitochondria hyperpolarization is an early event in oxidized low density lipoprotein-induced apoptosis in Caco-2 cells. FEBS Lett 523 (2002) 200-206
    • (2002) FEBS Lett , vol.523 , pp. 200-206
    • Giovannini, C.1    Matarrese, P.2    Scazzocchio, B.3    Sanchez, M.4    Masella, R.5    Malorni, W.6
  • 16
    • 0021067619 scopus 로고
    • Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture
    • Pinto M., Robine-Leon S., Appay M.D., Kedinger M., Triadou N., Dussaulx E., et al. Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture. Biol Cell 47 (1983) 323-330
    • (1983) Biol Cell , vol.47 , pp. 323-330
    • Pinto, M.1    Robine-Leon, S.2    Appay, M.D.3    Kedinger, M.4    Triadou, N.5    Dussaulx, E.6
  • 17
    • 0033880989 scopus 로고    scopus 로고
    • Lipid hydroperoxide-induced apoptosis in human colonic Caco-2 cells is associated with an early loss of cellular redox balance
    • Wang T.G., Gotoh Y., Jennings M.H., Rhoads C.A., and Aw T.Y. Lipid hydroperoxide-induced apoptosis in human colonic Caco-2 cells is associated with an early loss of cellular redox balance. FASEB J 14 (2000) 1567-1576
    • (2000) FASEB J , vol.14 , pp. 1567-1576
    • Wang, T.G.1    Gotoh, Y.2    Jennings, M.H.3    Rhoads, C.A.4    Aw, T.Y.5
  • 18
    • 0042626576 scopus 로고    scopus 로고
    • Influence of drugs and nutrients on transporter gene expression levels in Caco-2 and LS180 intestinal epithelial cells
    • Li Q., Sai Y., Kato Y., Tamai I., and Tsuji A. Influence of drugs and nutrients on transporter gene expression levels in Caco-2 and LS180 intestinal epithelial cells. Pharm Res 20 (2003) 1119-1124
    • (2003) Pharm Res , vol.20 , pp. 1119-1124
    • Li, Q.1    Sai, Y.2    Kato, Y.3    Tamai, I.4    Tsuji, A.5
  • 19
    • 0038509964 scopus 로고    scopus 로고
    • P66Shc: at the crossroad of oxidative stress and the genetics of aging
    • Purdom S., and Chen Q.M. P66Shc: at the crossroad of oxidative stress and the genetics of aging. Trends Mol Med 9 (2003) 206-210
    • (2003) Trends Mol Med , vol.9 , pp. 206-210
    • Purdom, S.1    Chen, Q.M.2
  • 20
    • 0035664651 scopus 로고    scopus 로고
    • Effects of dietary virgin olive oil phenols on low density lipoprotein oxidation in hyperlipidemic patients
    • Masella R., Giovannini C., Varì R., Di Benedetto R., Coni E., Volpe R., et al. Effects of dietary virgin olive oil phenols on low density lipoprotein oxidation in hyperlipidemic patients. Lipids 36 (2001) 1195-1202
    • (2001) Lipids , vol.36 , pp. 1195-1202
    • Masella, R.1    Giovannini, C.2    Varì, R.3    Di Benedetto, R.4    Coni, E.5    Volpe, R.6
  • 21
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissue
    • Folch J., Lees M., and Sloane-Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissue. J Biol Chem 226 (1957) 497-509
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane-Stanley, G.H.3
  • 22
    • 0034685681 scopus 로고    scopus 로고
    • Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis
    • Matarrese P., Tinari N., Semeraro M.L., Natoli C., Iacobelli S., and Malorni W. Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis. FEBS Lett 473 (2000) 311-315
    • (2000) FEBS Lett , vol.473 , pp. 311-315
    • Matarrese, P.1    Tinari, N.2    Semeraro, M.L.3    Natoli, C.4    Iacobelli, S.5    Malorni, W.6
  • 24
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the autoxidation of pyrogallol and convenient assay for superoxide dismutase
    • Marklund S., and Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and convenient assay for superoxide dismutase. Eur J Biochem 47 (1974) 469-474
    • (1974) Eur J Biochem , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 25
    • 2942584910 scopus 로고    scopus 로고
    • The life span determinant p66Shc localizes to mitochondria where it associates with mtHsp70 and regulates trans-membrane potential
    • Orsini F., Migliaccio E., Moroni M., Contursi C., Raker V.A., Piccini D., et al. The life span determinant p66Shc localizes to mitochondria where it associates with mtHsp70 and regulates trans-membrane potential. J Biol Chem 279 (2004) 25689-25695
    • (2004) J Biol Chem , vol.279 , pp. 25689-25695
    • Orsini, F.1    Migliaccio, E.2    Moroni, M.3    Contursi, C.4    Raker, V.A.5    Piccini, D.6
  • 27
    • 0034676493 scopus 로고    scopus 로고
    • Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology
    • Mates J.M. Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 153 (2000) 83-104
    • (2000) Toxicology , vol.153 , pp. 83-104
    • Mates, J.M.1
  • 28
    • 0032844918 scopus 로고    scopus 로고
    • Down regulation of superoxide dismutases and glutathione peroxidase by reactive oxygen and nitrogen species
    • Fujii J., and Taniguchi N. Down regulation of superoxide dismutases and glutathione peroxidase by reactive oxygen and nitrogen species. Free Radic Res 31 (1999) 301-308
    • (1999) Free Radic Res , vol.31 , pp. 301-308
    • Fujii, J.1    Taniguchi, N.2
  • 29
    • 0037423812 scopus 로고    scopus 로고
    • Induction of glutathione synthesis in macrophages by oxidized low-density lipoproteins is mediated by consensus antioxidant response elements
    • Bea F., Hudson F.N., Chait A., Kavanagh T.J., and Rosenfeld M.E. Induction of glutathione synthesis in macrophages by oxidized low-density lipoproteins is mediated by consensus antioxidant response elements. Circ Res 92 (2003) 386-393
    • (2003) Circ Res , vol.92 , pp. 386-393
    • Bea, F.1    Hudson, F.N.2    Chait, A.3    Kavanagh, T.J.4    Rosenfeld, M.E.5
  • 30
    • 0035578227 scopus 로고    scopus 로고
    • NF kappa B and AP-1 mediate transcriptional responses to oxidative stress in skeletal muscle cells
    • Zhou L.Z., Johnson A.P., and Rando T.A. NF kappa B and AP-1 mediate transcriptional responses to oxidative stress in skeletal muscle cells. Free Radic Biol Med 31 (2001) 1405-1416
    • (2001) Free Radic Biol Med , vol.31 , pp. 1405-1416
    • Zhou, L.Z.1    Johnson, A.P.2    Rando, T.A.3
  • 31
    • 0033805296 scopus 로고    scopus 로고
    • Triggering and modulation of apoptosis by oxidative stress
    • Chandra J., Samali A., and Orrenius S. Triggering and modulation of apoptosis by oxidative stress. Free Radic Biol Med 29 (2000) 323-333
    • (2000) Free Radic Biol Med , vol.29 , pp. 323-333
    • Chandra, J.1    Samali, A.2    Orrenius, S.3
  • 33
    • 0033581704 scopus 로고    scopus 로고
    • The p66shc adaptor protein controls oxidative stress response and life span in mammals
    • Migliaccio E., Giorgio M., Mele S., Pelicci G., Reboldi P., Pandolfi P.P., et al. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402 (1999) 243-245
    • (1999) Nature , vol.402 , pp. 243-245
    • Migliaccio, E.1    Giorgio, M.2    Mele, S.3    Pelicci, G.4    Reboldi, P.5    Pandolfi, P.P.6
  • 35
    • 85047695800 scopus 로고    scopus 로고
    • A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis
    • Trinei M., Giorgio M., Cicalese A., Barozzi S., Ventura A., Migliaccio E., et al. A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. Oncogene 21 (2002) 3872-3878
    • (2002) Oncogene , vol.21 , pp. 3872-3878
    • Trinei, M.1    Giorgio, M.2    Cicalese, A.3    Barozzi, S.4    Ventura, A.5    Migliaccio, E.6
  • 36
    • 0037452461 scopus 로고    scopus 로고
    • Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
    • Napoli C., Martin-Padura I., de Nigris F., Giorgio M., Mansueto G., Somma P., et al. Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. Proc Natl Acad Sci U S A 100 (2003) 2112-2116
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2112-2116
    • Napoli, C.1    Martin-Padura, I.2    de Nigris, F.3    Giorgio, M.4    Mansueto, G.5    Somma, P.6
  • 37
    • 25144482448 scopus 로고    scopus 로고
    • Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes
    • Masella R., Di Benedetto R., Varì R., Filesi C., and Giovannini C. Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. J Nutr Biochem 16 (2005) 577-586
    • (2005) J Nutr Biochem , vol.16 , pp. 577-586
    • Masella, R.1    Di Benedetto, R.2    Varì, R.3    Filesi, C.4    Giovannini, C.5
  • 38
    • 1842425919 scopus 로고    scopus 로고
    • Extra virgin olive oil biophenols inhibit cell-mediated oxidation of LDL by increasing the mRNA transcription of glutathione-related enzymes
    • Masella R., Varì R., D'Archivio M., Di Benedetto R., Matarrese P., Malorni W., et al. Extra virgin olive oil biophenols inhibit cell-mediated oxidation of LDL by increasing the mRNA transcription of glutathione-related enzymes. J Nutr 134 (2004) 785-791
    • (2004) J Nutr , vol.134 , pp. 785-791
    • Masella, R.1    Varì, R.2    D'Archivio, M.3    Di Benedetto, R.4    Matarrese, P.5    Malorni, W.6
  • 39
    • 0038606419 scopus 로고    scopus 로고
    • Berry intake increases the activity of the γ-glutamylcysteine synthetase promoter in transgenic reporter mice
    • Carlsen H., Myhrstad M.C., Thorensen M., Moskaug J.O., and Blomhoff R. Berry intake increases the activity of the γ-glutamylcysteine synthetase promoter in transgenic reporter mice. J Nutr 133 (2003) 2137-2140
    • (2003) J Nutr , vol.133 , pp. 2137-2140
    • Carlsen, H.1    Myhrstad, M.C.2    Thorensen, M.3    Moskaug, J.O.4    Blomhoff, R.5
  • 40
    • 0036489186 scopus 로고    scopus 로고
    • Flavonoids increase the intracellular glutathione level by transactivation of the γ-glutamylcysteine synthetase catalytic subunit promoter
    • Myhrstad M.C.W., Carlsen H., Nordstrom O., Blomhoff R., and Moskaug J.O. Flavonoids increase the intracellular glutathione level by transactivation of the γ-glutamylcysteine synthetase catalytic subunit promoter. Free Radic Biol Med 32 (2002) 386-393
    • (2002) Free Radic Biol Med , vol.32 , pp. 386-393
    • Myhrstad, M.C.W.1    Carlsen, H.2    Nordstrom, O.3    Blomhoff, R.4    Moskaug, J.O.5
  • 41
    • 0034573074 scopus 로고    scopus 로고
    • Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenols components during cell survival and death
    • Chen C., Yu R., Owuor E.D., and Kong A.N. Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenols components during cell survival and death. Arch Pharm Res 23 (2000) 605-612
    • (2000) Arch Pharm Res , vol.23 , pp. 605-612
    • Chen, C.1    Yu, R.2    Owuor, E.D.3    Kong, A.N.4
  • 42
    • 0035212419 scopus 로고    scopus 로고
    • Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE)
    • Kong A.N., Owuor E., Yu R., Hebbar V., Chen C., Hu R., et al. Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE). Drug Metab Rev 33 (2001) 255-271
    • (2001) Drug Metab Rev , vol.33 , pp. 255-271
    • Kong, A.N.1    Owuor, E.2    Yu, R.3    Hebbar, V.4    Chen, C.5    Hu, R.6
  • 44
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans: I. Review of 97 bioavailability studies
    • Manach C., Williamson G., Morand C., Scalbert A., and Rémésy C. Bioavailability and bioefficacy of polyphenols in humans: I. Review of 97 bioavailability studies. Am J Clin 81 Suppl (2005) 230S-242S
    • (2005) Am J Clin , vol.81 , Issue.SUPPL
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Rémésy, C.5
  • 45
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans: II. Review of 93 bioavailability studies
    • Williamson G., and Manach C. Bioavailability and bioefficacy of polyphenols in humans: II. Review of 93 bioavailability studies. Am J Clin 81 Suppl (2005) 230S-242S
    • (2005) Am J Clin , vol.81 , Issue.SUPPL
    • Williamson, G.1    Manach, C.2
  • 46
    • 0036183074 scopus 로고    scopus 로고
    • Evidence for consistent patterns between flavonoid structures and cellular activities
    • Depeint F., Gee J.M., Williamson G., and Johnson I.T. Evidence for consistent patterns between flavonoid structures and cellular activities. Proc Nutr Soc 61 (2002) 97-103
    • (2002) Proc Nutr Soc , vol.61 , pp. 97-103
    • Depeint, F.1    Gee, J.M.2    Williamson, G.3    Johnson, I.T.4
  • 47
    • 12144262315 scopus 로고    scopus 로고
    • Diet-derived phenols in plasma and tissues and their implications for health
    • Clifford M.N. Diet-derived phenols in plasma and tissues and their implications for health. Planta Med 70 12 (2004) 1103-1114
    • (2004) Planta Med , vol.70 , Issue.12 , pp. 1103-1114
    • Clifford, M.N.1


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