The active site of an algal prolyl 4-hydroxylase has a large structural plasticity

Journal of Biological Chemistry

Volumn 282, Issue 51, 2007, Pages 37112-37123

  Koski, M Kristian ^a   Hieta, Reija ^a   Böllner, Claudia ^a   Kivirikko, Kari I ^a   Myllyharju, Johanna ^a   Wierenga, Rik K ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN HOMEOSTASIS; PEPTIDYL PROLINES; STRUCTURAL PLASTICITY;

ENZYME ACTIVITY; HYDROXYLATION; OXYGEN; PLANT CELL CULTURE; PLASTICITY; SYNTHESIS (CHEMICAL);

COLLAGEN;

HYPOXIA INDUCIBLE FACTOR 1; OXOGLUTARATE DEHYDROGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE DERIVATIVE; PYRIDINE 2,4 DICARBOXYLATE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; ZINC;

ARTICLE; BETA CHAIN; BINDING SITE; CATALYSIS; CELL WALL; CHLAMYDOMONAS REINHARDTII; COLLAGEN SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITOR COMPLEX; ENZYME STRUCTURE; HOMEOSTASIS; HYDROXYLATION; MUTAGENESIS; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN DOMAIN;

ALGAL PROTEINS; ANIMALS; BINDING SITES; CELL WALL; CHLAMYDOMONAS REINHARDTII; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; PEPTIDES; PROCOLLAGEN-PROLINE DIOXYGENASE; PROLINE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; ZINC;

ALGAE; CHLAMYDOMONAS REINHARDTII; CHLOROPHYTA;

EID: 37549013372     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706554200     Document Type: Article

References (48)

1. Kivirikko, K. I., and Pihlajaniemi, T. (1998) Adv. Enzymol. Relat. Areas Mol. Biol. 72, 325-398
2. Myllyharju, J. (2003) Matrix Biol. 22, 15-24
3. Ozer, A., and Bruick, R. K. (2007) Nat. Chem. Biol. 3, 144-153
4. Myllyharju, J., and Kivirikko, K. I. (2004) Trends Genet. 20, 33-43
5. Kaelin, W. G., Jr. (2005) Biochem. Biophys. Res. Commun. 338, 627-638
6. Ratcliffe, P. J. (2006) Clin. Med. 6, 573-578
7. Kivirikko, K. I., Myllylä, R., and Pihlajaniemi, T. (1992) In Post-translational Modifications of Proteins (Harding, J. J., and Crabbe, M. J. C., eds) pp. 1-51, CRC Press, Inc., Boca Raton, FL
8. Keskiaho, K., Hieta, R., Sormunen, R., and Myllyharju, J. (2007) Plant Cell 19, 256-269
9. Kukkola, L., Hieta, R., Kivirikko, K. I., and Myllyharju, J. (2003) J. Biol. Chem. 278, 47685-47693
10. Myllyharju, J., and Kivirikko, K. I. (1999) EMBO J. 18, 306-312
11. Bruick, R. K., and McKnight, S. L. (2001) Science 294, 1337-1340
12. Epstein, A. C., Gleadle, J. M., McNeill, L. A., Hewitson, K. S., O'Rourke, J., Mole, D. R., Mukherji, M., Metzen, E., Wilson, M. I., Dhanda, A., Tian, Y.-M., Masson, N., Hamilton, D. L., Jaakkola, P., Barstead, R., Hodgkin, J., Maxwell, P. H., Pugh, C. W., Schofield, C. J., and Ratcliffe, P. J. (2001) Cell 107, 43-54
13. Ivan, M., Haberberger, T., Gervasi, D. C., Michelson, K. S., Günzler, V., Kondo, K., Yang, H., Sorokina, I., Conaway, R. C., Conaway, J. W., and Kaelin, W. G., Jr. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13459-13464
14. Taylor, M. S. (2001) Gene (Amst.) 275, 125-132
15. McDonough, M. A., Li, V., Flashman, E., Chowdhury, R., Mohr, C., Lienard, B. M., Zondlo, J., Oldham, N. J., Clifton, I. J., Lewis, J., McNeill, L. A., Kurzeja, R. J., Hewitson, K. S., Yang, E., Jordan, S., Syed, R. S., and Schofield, C. J. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 9814-9819
16. Choi, K.-O., Lee, T., Lee, N., Kim, J.-H., Yang, E. G., Yoon, J. M., Kim, J. H., Lee, T. G., and Park, H. (2005) Mol. Pharmacol. 68, 1803-1809
17. Hieta, R., and Myllyharju, J. (2002) J. Biol. Chem. 277, 23965-23971
18. Tiainen, P., Myllyharju, J., and Koivunen, P. (2005) J. Biol. Chem. 280, 1142-1148
19. Yuasa, K., Toyooka, K., Fukuda, H., and Matsuoka, K. (2005) Plant J. 41, 81-94
20. Eriksson, M., Myllyharju, J., Tu, H., Hellman, M., and Kivirikko, K. I. (1999) J. Biol. Chem. 274, 22131-22134
21. Myllyharju, J., and Kivirikko, K. I. (1997) EMBO J. 16, 1173-1180
22. Clifton, I. J., McDonough, M. A., Ehrismann, D., Kershaw, N. J., Granatino, N., and Schofield, C. J. (2006) J. Inorg. Biochem. 100, 644-669
23. Hieta, R., Kukkola, L., Permi, P., Pirilä, P., Kivirikko, K. I., Kilpeläinen, I., and Myllyharju, J. (2003) J. Biol. Chem. 278, 34966-34974
24. Pekkala, M., Hieta, R., Bergmann, U., Kivirikko, K. I., Wierenga, R. K., and Myllyharju, J. (2004) J. Biol. Chem. 279, 52255-52261
25. Hirsilä, M., Koivunen, P., Günzler, V., Kivirikko, K. I., and Myllyharju, J. (2003) J. Biol. Chem. 278, 30772-30780
26. Kabsch, W. (1993) J. Appl. Crystallogr. 26, 795-800
27. Terwilliger, T. C., and Berendzen, J. (1999) Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 849-861
28. Terwilliger, T. C. (2002) Acta Crystallogr. Sect. D Biol. Crystallogr. 59, 34-44
29. CCP4 (1994) Acta Crystallogr. Sect. D Biol. Crystallogr. 50, 760-763
30. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. Sect. D Biol. Crystallogr. 53, 240-255
31. Jones, T. A., Zou, J. Y., Cowen, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. Sect. A Found. Crystallogr. 47, 110-119
32. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. Sect. D Biol. Crystallogr. 60, 2126-2132
33. McCoy, A. J., Grosse-Kunstleve, R. W., Storoni, L. C., and Read, R. J. (2005) Acta Crystallogr. Sect. D Biol. Crystallogr. 61, 458-464
34. Vriend, G. (1990) J. Mol. Graph. 8, 52-56
35. Lovell, S. C., Davis, I. W., Arendall, W. B., III, de Bakker, P. I. W., Word, J. M., Prisant, M. G., Richardson, J. S., and Richardson, D. C. (2003) Proteins 50, 437-450
36. Guex, N., and Peitsch, M. C. (1997) Electrophoresis 18, 2714-2723
37. Hirsilä, M., Koivunen, P., Xu, L., Seeley, T., Kivirikko, K. I., and Myllyharju, J. (2005) FASEB J. 19, 1308-1310
38. Yu, B., Edstrom, W. C., Benach, J., Hamuro, Y., Weber, P. C., Gibney, B. R., and Hunt, J. F. (2006) Nature 439, 879-884
39. Blasiak, L. C., Vaillancourt, F. H., Walsh, C. T., and Drennan, C. L. (2006) Nature 440, 368-371
40. Holm, L., and Sander, C. (1996) Science 273, 595-603
41. Zhang, Z., Ren, J., Stammers, D. K., Baldwin, J. E., Harlos, K., and Schofield, C. J. (2000) Nat. Struct. Biol. 7, 127-133
42. Dann, C. E., III, Bruick, R. K., and Deisenhofer, J. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 15351-15356
43. Elkins, J. M., Hewitson, K. S., McNeill, L. A., Seibel, J. F., Schlemminger, I., Pugh, C. W., Ratcliffe, P. J., and Schofield, C. J. (2003) J. Biol. Chem. 278, 1802-1806
44. Lee, C., Kim, S. J., Jeong, D. G., Lee, S. M., and Ryu, S. E. (2003) J. Biol. Chem. 278, 7558-7563
45. Clifton, I. J., Hsueh, L. C., Baldwin, J. E., Harlos, K., and Schofield, C. J. (2001) Eur. J. Biochem. 268, 6625-6636
46. Zhang, Z., Ren, J., Harlos, K., McKinnon, C. H., Clifton, I. J., and Schofield, C. J. (2002) FEBS Lett. 517, 7-12
47. Clifton, I. J., Doan, L. X., Sleeman, M. C., Topf, M., Suzuki, H., Wilmouth, R. C., and Schofield, C. J. (2003) J. Biol. Chem. 278, 20843-20850
48. Lloyd, M. D., Lee, H. J., Harlos, K., Zhang, Z. H., Baldwin, J. E., Schofield, C. J., Charnock, J. M., Garner, C. D., Hara, T., Terwisscha van Scheltinga, A. C., Valegård, K., Viklund, J. A., Hajdu, J., Andersson, I., Danielsson, A., and Bhikhabhai, R. (1999) J. Mol. Biol. 287, 943-960