Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

Nature

Volumn 440, Issue 7082, 2006, Pages 368-371

  Blasiak, Leah C ^a   Vaillancourt, Frédéric H ^b,c   Walsh, Christopher T ^b   Drennan, Catherine L ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BOEHRINGER INGELHEIM CANADA LTD   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CARBOXYLATION; CATALYSIS; DNA; ENZYMES; IRON COMPOUNDS;

CHLORIDE ION; LIGANDS; THREONINE;

CRYSTAL STRUCTURE;

2 OXOGLUTARIC ACID; CARBOXYLIC ACID; CHLORIDE ION; ENZYME; ENZYME SYRB2; HEME; IRON; SYRINGOMYCIN; UNCLASSIFIED DRUG;

CRYSTAL STRUCTURE;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; PRIORITY JOURNAL;

HARNESS; MAMMALIA;

EID: 33645017788     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04544     Document Type: Article

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