Interference of glycine transporter 1: Modulation of cognitive functions via activation of glycine-B site of the NMDA receptor

Central Nervous System Agents in Medicinal Chemistry

Volumn 7, Issue 4, 2007, Pages 259-268

  Singer, Philipp ^a   Feldon, Joram ^a   Yee, Benjamin K ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Cognitive enhancer; Glutamate; Glycine; GlyT1; Learning and memory; NMDA; Schizophrenia

Indexed keywords

2 CHLORO N [ALPHA (2 PIPERIDINYL)BENZYL] 3 TRIFLUOROMETHYLBENZAMIDE; [3 (4 CHLOROPHENYL) 3 [4 (THIAZOLA 2 CARBONYL)PHENOXY]PROPYL]METHYLAMINO ACETIC ACID; ALX 5407; AMINO ACID RECEPTOR AFFECTING AGENT; CP 802079; CYCLOSERINE; DEXTRO SERINE; DIZOCILPINE; GLYCINE; GLYCINE TRANSPORTER 1; HALOPERIDOL; N [3 (4' FLUOROPHENYL) 3 (4' PHENOXY)PROPYL]SARCOSINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL N [3 [(4 TRIFLUOROMETHYL) PHENOXY] 3 PHENYL PROPYL]GLYCINE; NEUROLEPTIC AGENT; ORG 24461; ORG 24598; SARCOSINE; UNCLASSIFIED DRUG;

AKATHISIA; AUDITORY RESPONSE; BEHAVIOR; BINDING SITE; BLOOD BRAIN BARRIER; CLEARANCE; COGNITION; CONVULSION; DRUG MEGADOSE; ELECTROPHYSIOLOGY; HUMAN; INHIBITION KINETICS; KNOCKOUT MOUSE; LATENT INHIBITION; LEARNING; MAZE TEST; MEMORY; MENTAL DISEASE; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NEUROMODULATION; NONHUMAN; PREPULSE INHIBITION; PROTEIN TRANSPORT; RECEPTOR DOWN REGULATION; RECOGNITION; REFERENCE MEMORY; REGULATORY MECHANISM; REVIEW; SCHIZOPHRENIA; SPATIAL MEMORY; STATE DEPENDENT LEARNING;

EID: 37349109630     PISSN: 18715249     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152407783220841     Document Type: Review

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