Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors

BMC Genomics

Volumn 8, Issue , 2007, Pages

  Schroeder, Tania M ^a   Nair, Aswathy K ^a   Staggs, Rodney ^a   Lamblin, Anne Francoise ^a   Westendorf, Jennifer J ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; FRIZZLED PROTEIN; GLUTATHIONE TRANSFERASE A4; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; HISTONE DEACETYLASE INHIBITOR; IDITOL DEHYDROGENASE; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; PROTEASOME; SODIUM PROTON EXCHANGE PROTEIN 3; TRICHOSTATIN A; VALPROIC ACID; WNT PROTEIN; ALKALINE PHOSPHATASE; ENZYME INHIBITOR; HISTONE DEACETYLASE;

ANIMAL CELL; ARTICLE; BONE DENSITY; BONE DEVELOPMENT; BONE MATURATION; CELL DIFFERENTIATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE INDUCTION; GENE REPRESSION; GENETIC ANALYSIS; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; CELL STRAIN 3T3; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; OSTEOBLAST; POLYMERASE CHAIN REACTION;

3T3 CELLS; ALKALINE PHOSPHATASE; ANIMALS; CELL DIFFERENTIATION; ENZYME INHIBITORS; GENE EXPRESSION PROFILING; HISTONE DEACETYLASES; MICE; OSTEOBLASTS; POLYMERASE CHAIN REACTION;

EID: 37249075061     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-8-362     Document Type: Article

References (40)

1. Grunstein M Histone acetylation in chromatin structure and transcription Nature 1997, 389(6649):349-352 10.1038/38664 9311776
2. Peterson CL Laniel MA Histones and histone modifications Curr Biol 2004, 14(14):R546-51 10.1016/j.cub.2004.07.007 15268870
3. Gray SG Ekstrom TJ The Human Histone Deacetylase Family Exp Cell Res 2001, 262(2):75-83 10.1006/excr.2000.5080 11139331
4. Gregoretti IV Lee YM Goodson HV Molecular evolution of the histone deacetylase family: Functional implications of phylogenetic analysis J Mol Biol 2004, 338(1):17-31 10.1016/j.jmb.2004.02.006 15050820
5. Yang XJ Gregoire S Class II histone deacetylases: From sequence to function, regulation, and clinical implication Mol Cell Biol 2005, 25(8):2873-2884 1069616 15798178 10.1128/MCB.25.8.2873-2884.2005
6. Blander G Guarente L The Sir2 family of protein deacetylases Annu Rev Biochem 2004, 73:417-435 10.1146/annurev.biochem.73.011303.073651 15189148
7. Yoshida M Matsuyama A Komatsu Y Nishino N From discovery to the coming generation of histone deacetylase inhibitors Curr Med Chem 2003, 10(22):2351-2358 10.2174/0929867033456602 14529478
8. Gurvich N Tsygankova OM Meinkoth JL Klein PS Histone deacetylase is a target of valproic acid-mediated cellular differentiation Cancer Res 2004, 64(3):1079-1086 10.1158/0008-5472.CAN-03-0799 14871841
9. Hu E Dul E Sung CM Chen Z Kirkpatrick R Zhang GF Johanson K Liu R Lago A Hofmann G Macarron R de los Frailes M Perez P Krawiec J Winkler J Jaye M Identification of novel isoform-selective inhibitors within class I histone deacetylases J Pharmacol Exp Ther 2003, 307(2):720-728 10.1124/ jpet.103.055541 12975486
10. Minucci S Pelicci PG Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer Nat Rev Cancer 2006, 6(1):38-51 10.1038/nrc1779 16397526
11. Finnin MS Donigian JR Cohen A Richon VM Rifkind RA Marks PA Breslow R Pavletich NP Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors Nature 1999, 401(6749):188-193 10.1038/43710 10490031
12. Acharya MR Sparreboom A Venitz J Figg WD Rational Development of Histone Deacetylase Inhibitors as Anti-cancer Agents: A Review Mol Pharmacol 2005. 15955865
13. Phiel CJ Zhang F Huang EY Guenther MG Lazar MA Klein PS Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen J Biol Chem 2001, 276(39):36734-36741 10.1074/jbc.M101287200 11473107
14. Blanchard F Chipoy C Histone deacetylase inhibitors: New drugs for the treatment of inflammatory diseases? Drug Discov Today 2005, 10(3):197-204 10.1016/S1359-6446(04)03309-4 15708534
15. McKinsey TA Olson EN Cardiac histone acetylation--therapeutic opportunities abound Trends Genet 2004, 20(4):206-213 10.1016/ j.tig.2004.02.002 15041175
16. Qiu L Burgess A Fairlie DP Leonard H Parsons PG Gabrielli BG Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells Mol Biol Cell 2000, 11(6):2069-2083 14904 10848630
17. Burgess A Ruefli A Beamish H Warrener R Saunders N Johnstone R Gabrielli B Histone deacetylase inhibitors specifically kill nonproliferating tumour cells Oncogene 2004, 23(40):6693-6701 10.1038/sj.onc.1207893 15235588
18. Schroeder TM Westendorf JJ Histone deacetylase inhibitors promote osteoblast maturation J Bone Miner Res 2005, 20(12):2254-2263 10.1359/ JBMR.050813 16294278
19. Iwami K Moriyama T Effects of short chain fatty acid, sodium butyrate, on osteoblastic cells and osteoclastic cells Int J Biochem 1993, 25(11):1631-1635 10.1016/0020-711X(93)90522-G 8288032
20. Sakata R Minami S Sowa Y Yoshida M Tamaki T Trichostatin A activates the osteopontin gene promoter through AP1 site Biochem Biophys Res Commun 2004, 315(4):959-963 10.1016/j.bbrc.2004.01.152 14985105
21. Jeon EJ Lee KY Choi NS Lee MH Kim HN Jin YH Ryoo HM Choi JY Yoshida M Nishino N Oh BC Lee KS Lee YH Bae SC Bone morphogenetic protein-2 stimulates Runx2 acetylation J Biol Chem 2006, 281(24):16502-16511 10.1074/jbc.M512494200 16613856
22. Lee HW Suh JH Kim AY Lee YS Park SY Kim JB Histone deacetylase 1-mediated histone modification regulates osteoblast differentiation Mol Endocrinol 2006, 20(10):2432-2443 10.1210/me.2006-0061 16728531
23. Smith E Frenkel B Glucocorticoids inhibit the transcriptional activity of LEF/TCF in differentiating osteoblasts in a glycogen synthase kinase-3beta-dependent and -independent manner J Biol Chem 2005, 280(3):2388-2394 10.1074/jbc.M406294200 15537647
24. Cho HH Park HT Kim YJ Bae YC Suh KT Jung JS Induction of osteogenic differentiation of human mesenchymal stem cells by histone deacetylase inhibitors J Cell Biochem 2005.
25. Boer JD Licht R Bongers M Klundert TV Arends R Blitterswijk CV Inhibition of Histone Acetylation as a Tool in Bone Tissue Engineering Tissue Eng 2006.
26. Schroeder TM Kahler RA Li X Westendorf JJ Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation J Biol Chem 2004, 279(40):41998-42007 10.1074/ jbc.M403702200 15292260
27. Edgar R Domrachev M Lash AE Gene Expression Omnibus: NCBI gene expression and hybridization array data repository Nucleic Acids Res 2002, 30(1):207-210 99122 11752295 10.1093/nar/30.1.207
28. Qin L Tamasi J Raggatt L Li X Feyen JH Lee DC Dicicco-Bloom E Partridge NC Amphiregulin is a novel growth factor involved in normal bone development and in the cellular response to parathyroid hormone stimulation J Biol Chem 2005, 280(5):3974-3981 10.1074/jbc.M409807200 15509566
29. Roman-Roman S Shi DL Stiot V Hay E Vayssiere B Garcia T Baron R Rawadi G Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/ beta-catenin signaling J Biol Chem 2004, 279(7):5725-5733 10.1074/ jbc.M309233200 14627707
30. Bretscher A Chambers D Nguyen R Reczek D ERM-Merlin and EBP50 protein families in plasma membrane organization and function Annu Rev Cell Dev Biol 2000, 16:113-143 10.1146/annurev.cellbio.16.1.113 11031232
31. Weinman EJ Hall RA Friedman PA Liu-Chen LY Shenolikar S The Association Of Nherf Adaptor Proteins With G Protein-Coupled Receptors And Receptor Tyrosine Kinases Annu Rev Physiol 2006, 68:491-505 10.1146/ annurev.physiol.68.040104.131050 16460281
32. Sneddon WB Syme CA Bisello A Magyar CE Rochdi MD Parent JL Weinman EJ Abou-Samra AB Friedman PA Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50) J Biol Chem 2003, 278(44):43787-43796 10.1074/jbc.M306019200 12920119
33. Shibata T Chuma M Kokubu A Sakamoto M Hirohashi S EBP50, a beta-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma Hepatology 2003, 38(1):178-186 10.1053/jhep.2003.50270 12830000
34. Shenolikar S Voltz JW Minkoff CM Wade JB Weinman EJ Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting Proc Natl Acad Sci U S A 2002, 99(17):11470-11475 123280 12169661 10.1073/ pnas.162232699
35. Glickman MH Ciechanover A The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction Physiol Rev 2002, 82(2):373-428 11917093
36. Garrett IR Chen D Gutierrez G Zhao M Escobedo A Rossini G Harris SE Gallwitz W Kim KB Hu S Crews CM Mundy GR Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro J Clin Invest 2003, 111(11):1771-1782 156102 12782679 10.1172/JCI200316198
37. Zhao M Qiao M Harris SE Oyajobi BO Mundy GR Chen D Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo J Biol Chem 2004, 279(13):12854-12859 10.1074/jbc.M313294200 14701828
38. Xu Q Wang Y Dabdoub A Smallwood PM Williams J Woods C Kelley MW Jiang L Tasman W Zhang K Nathans J Vascular development in the retina and inner ear: Control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair Cell 2004, 116(6):883-895 10.1016/S0092-8674(04)00216-8 15035989
39. Westendorf JJ Kahler RA Schroeder TM Wnt signaling in osteoblasts and bone diseases Gene 2004, 341:19-39 10.1016/j.gene.2004.06.044 15474285
40. Irizarry RA Hobbs B Collin F Beazer-Barclay YD Antonellis KJ Scherf U Speed TP Exploration, normalization, and summaries of high density oligonucleotide array probe level data Biostatistics 2003, 4(2):249-264 10.1093/biostatistics/4.2.249 12925520