Amphiregulin is a novel growth factor involved in normal bone development and in the cellular response to parathyroid hormone stimulation

Journal of Biological Chemistry

Volumn 280, Issue 5, 2005, Pages 3974-3981

  Qin, Ling ^a   Tamasi, Joseph ^b   Raggatt, Liza ^a   Li, Xin ^a   Feyen, Jean H M ^b   Lee, David C ^c   DiCicco Bloom, Emanuel ^a   Partridge, Nicola C ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CELLS; DRUG PRODUCTS; GROWTH KINETICS; METABOLISM; PHYSIOLOGICAL MODELS; TISSUE;

AMPHIREGULIN; BONE DEVELOPMENT; EPIDERMAL GROWTH FACTOR (EGF); PARATHYROID HORMONE (PTH);

HORMONES;

AMPHIREGULIN; CALCITRIOL; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; PARATHYROID HORMONE; PROSTAGLANDIN E2; PROTEIN C FOS; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE METABOLISM; BONE REMODELING; BONE TISSUE; CALCIUM HOMEOSTASIS; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; MALE; NONHUMAN; OSTEOBLAST; OSTEOPOROSIS; PARATHYROID HORMONE RELEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TRABECULAR BONE; UPREGULATION;

ANIMALS; BONE AND BONES; BONE DEVELOPMENT; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLYCOPROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MALE; MICE; MICE, MUTANT STRAINS; OSTEOBLASTS; PARATHYROID HORMONE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 13544265673     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409807200     Document Type: Article

References (40)

1. Tam, C. S., Heersche, J. N., Murray, T. M., and Parsons, J. A. (1982) Endocrinology 110, 506-512
2. Schiller, P. C., D'Ippolito, G., Roos, B. A., and Howard, G. A. (1999) J. Bone Miner. Res. 14, 1504-1512
3. Dobnig, H., and Turner, R. T. (1995) Endocrinology 136, 3632-3638
4. Juppner, H., Abou-Samra, A. B., Freeman, M., Kong, X. F., Schipani, E., Richards, J., Kolakowski, L. F., Jr., Hock, J., Potts, J. T., Jr., and Kronenberg, H. M. (1991) Science 254, 1024-1026
5. Swarthout, J. T., D'Alonzo, R. C., Selvamurugan, N., and Partridge, N. C. (2002) Gene (Amst.) 282, 1-17
6. Qin, L., Qiu, P., Wang, L., Li, X., Swarthout, J. T., Soteropoulos, P., Tolias, P., and Partridge, N. C. (2003) J. Biol. Chem. 278, 19723-19731
7. Mendelsohn, J., and Baselga, J. (2000) Oncogene 19, 6550-6565
8. Yarden, Y. (2001) Eur. J. Cancer 37, S3-S8
9. Alroy, I., and Yarden, Y. (1997) FEBS Lett. 410, 83-86
10. Burgering, B. M., and Coffer, P. J. (1995) Nature 376, 599-602
11. Shoyab, M., Plowman, G. D., McDonald, V. L., Bradley, J. G., and Todaro, G. J. (1989) Science 243, 1074-1076
12. Shoyab, M., McDonald, V. L., Bradley, J. G., and Todaro, G. J. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 6528-6532
13. Plowman, G. D., Green, J. M., McDonald, V. L., Neubauer, M. G., Disteche, C. M., Todaro, G. J., and Shoyab, M. (1990) Mol. Cell. Biol. 10, 1969-1981
14. Cook, P. W., Mattox, P. A., Keeble, W. W., Pittelkow, M. R., Plowman, G. D., Shoyab, M., Adelman, J. P., and Shipley, G. D. (1991) Mol. Cell. Biol. 11, 2547-2557
15. Ng, K. W., Partridge, N. C., Niall, M., and Martin, T. J. (1983) Calcif. Tissue Int. 35, 624-628
16. Kumegawa, M., Hiramatsu, M., Hatakeyama, K., Yajima, T., Kodama, H., Osaki, T., and Kurisu, K. (1983) Calcif. Tissue Int. 35, 542-548
17. Hata, R., Hori, H., Nagai, Y., Tanaka, S., Kondo, M., Hiramatsu, M., Utsumi, N., and Kumegawa, M. (1984) Endocrinology 115, 867-876
18. Antosz, M. E., Bellows, C. G., and Aubin, J. E. (1987) J. Bone Miner. Res. 2, 385-393
19. Raisz, L. G., Simmons, H. A., Sandberg, A. L., and Canalis, E. (1980) Endocrinology 107, 270-273
20. Shalhoub, V., Conlon, D., Tassinari, M., Quinn, C., Partridge, N., Stein, G. S., and Lian, J. B. (1992) J. Cell. Biochem. 50, 425-440
21. Onyia, J. E., Bidwell, J., Herring, J., Hulman, J., and Hock, J. M. (1995) Bone 17, 479-484
22. Swarthout, J. T., Tyson, D. R., Jefcoat, S. C., Jr., and Partridge, N. C. (2002) J. Bone Miner. Res. 17, 1401-1407
23. Luetteke, N. C., Qiu, T. H., Fenton, S. E., Troyer, K. L., Riedel, R. F., Chang, A., and Lee, D. C. (1999) Development 126, 2739-2750
24. Gunness-Hey, M., and Hock, J. M. (1984) Metab. Bone Dis. Relat. Res. 5, 177-181
25. Akutsu, N., Bastien, Y., Lin, R., Mader, S., and White, J. H. (2001) Biochem. Biophys. Res. Commun. 281, 1051-1056
26. Partridge, N. C., Opie, A. L., Opie, R. T., and Martin, T. J. (1985) Calcif. Tissue Int. 37, 519-525
27. Onishi, T., and Hruska, K. (1997) Endocrinology 138, 1995-2004
28. Seger, R., and Krebs, E. G. (1995) FASEB J. 9, 726-735
29. Lee, S. K., and Lorenzo, J. A. (1999) Endocrinology 140, 3552-3561
30. Calvi, L. M., Adams, G. B., Weibrecht, K. W., Weber, J. M., Olson, D. P., Knight, M. C., Martin, R. P., Schipani, E., Divieti, P., Bringhurst, F. R., Milner, L. A., Kronenberg, H. M., and Scadden, D. T. (2003) Nature 425, 841-846
31. Satomura, K., Derubeis, A. R., Fedarko, N. S., Ibaraki-O'Connor, K., Kuznetsov, S. A., Rowe, D. W., Young, M. F., and Gehron Robey, P. (1998) J. Cell. Physiol. 177, 426-438
32. Gronthos, S., and Simmons, P. J. (1995) Blood 85, 929-940
33. Bernier, S. M., and Goltzman, D. (1992) J. Cell. Physiol. 152, 317-327
34. Kretzschmar, M., Doody, J., and Massague, J. (1997) Nature 389, 618-622
35. Drake, M. T., Baldassare, J. J., McConkey, C. L., Gonzalez, E. A., and Martin, K. J. (1994) Endocrinology 134, 1733-1737
36. Troyer, K. L., Luetteke, N. C., Saxon, M. L., Qiu, T. H., Xian, C. J., and Lee, D. C. (2001) Gastroenterology 121, 68-78
37. Miettinen, P. J., Berger, J. E., Meneses, J., Phung, Y., Pedersen, R. A., Werb, Z., and Derynck, R. (1995) Nature 376, 337-341
38. Threadgill, D. W., Dlugosz, A. A., Hansen, L. A., Tennenbaum, T., Lichti, U., Yee, D., LaMantia, C., Mourton, T., Herrup, K., and Harris, R. C. (1995) Science 269, 230-234
39. Sibilia, M., and Wagner, E. F. (1995) Science 269, 234-238
40. Sibilia, M., Wagner, B., Hoebertz, A., Elliott, C., Marino, S., Jochum, W., and Wagner, E. F. (2003) Development 130, 4515-4525