MicroRNAs in vertebrate synapse development

TheScientificWorldJournal

Volumn 7, Issue SUPPL. 2, 2007, Pages 167-177

  Fiore, Roberto ^a   Schratt, Gerhard ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

BDNF; Dendritic spine; Local translation; MicroRNA; Synapse

Indexed keywords

MICRORNA;

COGNITION; GENE EXPRESSION; GENE FUNCTION; HUMAN; LEARNING; MEMORY; NERVE CELL; NERVE CELL PLASTICITY; NEUROLOGIC DISEASE; SHORT SURVEY; SYNAPSE; VERTEBRATE;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; MICRORNAS; NERVOUS SYSTEM DISEASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; SYNAPSES; VERTEBRATES;

VERTEBRATA;

EID: 37249055188     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2007.196     Document Type: Short Survey

References (62)

1. Waites, C.L., Craig, A.M., and Garner, C.C. (2005) Mechanisms of vertebrate synaptogenesis. Annu. Rev. Neurosci. 28, 251-274.
2. McAllister, A.K. (2007) Dynamic aspects of CNS synapse formation. Annu. Rev. Neurosci. 30, 425-450.
3. Kang, H. and Schuman, E.M. (1996) A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity. Science 273, 1402-1406.
4. Costa-Mattioli, M., Gobert, D., Harding, H., Herdy, B., Azzi, M., Bruno, M., Bidinosti, M., Ben Mamou, C., Marcinkiewicz, E., Yoshida, M., Imataka, H., Cuello, A.C., Seidah, N., Sossin, W., Lacaille, J.C., Ron, D., Nader, K., and Sonenberg, N. (2005) Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2. Nature 436, 1166-1173.
5. DiAntonio, A. and Hicke, L. (2004) Ubiquitin-dependent regulation of the synapse. Annu. Rev. Neurosci. 27, 223-246.
6. Shi, S.H., Hayashi, Y., Petralia, R.S., Zaman, S.H., Wenthold, R.J., Svoboda, K., and Malinow, R. (1999) Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation [see comments]. Science 284, 1811-1816.
7. Malenka, R.C. and Nicoll, R.A. (1999) Long-term potentiation - a decade of progress? Science 285, 1870-1874.
8. El-Husseini Ael, D., Schnell, E., Dakoji, S., Sweeney, N., Zhou, Q., Prange, O., Gauthier-Campbell, C., Aguilera-Moreno, A., Nicoll, R.A., and Bredt, D.S. (2002) Synaptic strength regulated by palmitate cycling on PSD-95. Cell 108, 849-863.
9. Washbourne, P. (2004) Greasing transmission: palmitoylation at the synapse. Neuron 44, 901-902.
10. deSouza, S. and Ziff, E.B. (2002) AMPA receptors do the electric slide. Sci. STKE 2002, PE45.
11. Zito, K., Knott, G., Shepherd, G.M., Shenolikar, S., and Svoboda, K. (2004) Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton. Neuron 44, 321-334.
12. Okamoto, K., Nagai, T., Miyawaki, A., and Hayashi, Y. (2004) Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nat. Neurosci. 7, 1104-1112.
13. Bamburg, J.R. (1999) Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu. Rev. Cell Dev. Biol. 15, 185-230.
14. Yi, J.J. and Ehlers, M.D. (2005) Ubiquitin and protein turnover in synapse function. Neuron 47, 629-632.
15. Bingol, B. and Schuman, E.M. (2005) Synaptic protein degradation by the ubiquitin proteasome system. Curr. Opin. Neurobiol. 15, 536-541.
16. Wells, D.G., Richter, J.D., and Fallon, J.R. (2000) Molecular mechanisms for activity-regulated protein synthesis in the synapto-dendritic compartment. Curr. Opin. Neurobiol. 10, 132-137.
17. Huber, K.M., Kayser, M.S., and Bear, M.F. (2000) Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression. Science 288, 1254-1257.
18. Kelleher, R.J., 3rd, Govindarajan, A., Jung, H.Y., Kang, H., and Tonegawa, S. (2004) Translational control by MAPK signaling in long-term synaptic plasticity and memory. Cell 116, 467-479.
19. Steward, O. and Schuman, E.M. (2001) Protein synthesis at synaptic sites on dendrites. Annu. Rev. Neurosci. 24, 299-325.
20. Eberwine, J., Miyashiro, K., Kacharmina, J.E., and Job, C. (2001) Local translation of classes of mRNAs that are targeted to neuronal dendrites. Proc. Natl. Acad. Sci. U. S. A. 98, 7080-7085.
21. Steward, O., Wallace, C.S., Lyford, G.L., and Worley, P.F. (1998) Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 21, 741-751.
22. Schratt, G.M., Nigh, E.A., Chen, W.G., Hu, L., and Greenberg, M.E. (2004) BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development. J. Neurosci. 24, 9366-9377.
23. West, A.E., Griffith, E.C., and Greenberg, M.E. (2002) Regulation of transcription factors by neuronal activity. Nat. Rev. Neurosci. 3, 921-931.
24. Zeng, Y. and Cullen, B.R. (2006) Recognition and cleavage of primary microRNA transcripts. Methods Mol. Biol. 342, 49-56.
25. Zeng, Y., Yi, R., and Cullen, B.R. (2005) Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J. 24, 138-148.
26. Lund, E., Guttinger, S., Calado, A., Dahlberg, J.E., and Kutay, U. (2004) Nuclear export of microRNA precursors. Science 303, 95-98.
27. Forstemann, K., Tomari, Y., Du, T., Vagin, V.V., Denli, A.M., Bratu, D.P., Klattenhoff, C., Theurkauf, W.E., and Zamore, P.D. (2005) Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol. 3, e236.
28. Saito, K., Ishizuka, A., Siomi, H., and Siomi, M.C. (2005) Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol. 3, e235.
29. Bartel, D.P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297.
30. Kloosterman, W.P. and Plasterk, R.H. (2006) The diverse functions of microRNAs in animal development and disease. Dev. Cell 11, 441-450.
31. Lewis, B.P., Burge, C.B., and Bartel, D.P. (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20.
32. Chang, S., Johnston, R.J.J., Frokjaer-Jensen, C., Lockery, S., and Hobert, O. (2004) MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode. Nature 430, 785-789.
33. Li, Y., Wang, F., Lee, J.A., and Gao, F.B. (2006) MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila. Genes Dev. 20, 2793-2805.
34. Li, X. and Carthew, R.W. (2005) A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye. Cell 123, 1267-1277.
35. Giraldez, A.J., Cinalli, R.M., Glasner, M.E., Enright, A.J., Thomson, J.M., Baskerville, S., Hammond, S.M., Bartel, D.P., and Schier, A.F. (2005) MicroRNAs regulate brain morphogenesis in zebrafish. Science 308, 833-838.
36. Miska, E.A., Alvarez-Saavedra, E., Townsend, M., Yoshii, A., Sestan, N., Rakic, P., Constantine-Paton, M., and Horvitz, H.R. (2004) Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol. 5, R68.
37. Sempere, L.F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E., and Ambros, V. (2004) Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 5, R13.
38. Conaco, C., Otto, S., Han, J.J., and Mandel, G. (2006) Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl. Acad. Sci. U. S. A. 103, 2422-2427.
39. Cao, X., Pfaff, S.L., and Gage, F.H. (2007) A functional study of miR-124 in the developing neural tube. Genes Dev. 21, 531-536.
40. Visvanathan, J., Lee, S., Lee, B., Lee, J.W., and Lee, S.K. (2007) The microRNA miR-124 antagonizes the antineural REST/SCP1 pathway during embryonic CNS development. Genes Dev. 21, 744-749.
41. Lim, L.P., Lau, N.C., Garrett-Engele, P., Grimson, A., Schelter, J.M., Castle, J., Bartel, D.P., Linsley, P.S., and Johnson, J.M. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433, 769-773.
42. Caudy, A.A., Myers, M., Hannon, G.J., and Hammond, S.M. (2002) Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev. 16, 2491-2496.
43. Jin, P., Zarnescu, D.C., Ceman, S., Nakamoto, M., Mowrey, J., Jongens, T.A., Nelson, D.L., Moses, K., and Warren, S.T. (2004) Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat. Neurosci. 7, 113-117.
44. Barbee, S.A., Estes, P.S., Cziko, A.M., Hillebrand, J., Luedeman, R.A., Coller, J.M., Johnson, N., Howlett, I.C., Geng, C., Ueda, R., Brand, A.H., Newbury, S.F., Wilhelm, J.E., Levine, R.B., Nakamura, A., Parker, R., and Ramaswami, M. (2006) Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies. Neuron 52, 997-1009.
45. Ashraf, S.I., McLoon, A.L., Sclarsic, S.M., and Kunes, S. (2006) Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila. Cell 124, 191-205.
46. Vo, N., Klein, M.E., Varlamova, O., Keller, D.M., Yamamoto, T., Goodman, R.H., and Impey, S. (2005) A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc. Natl. Acad. Sci. U. S. A. 102, 16426-16431.
47. Schratt, G.M., Tuebing, F., Nigh, E.A., Kane, C.G., Sabatini, M.E., Kiebler, M., and Greenberg, M.E. (2006) A brain-specific microRNA regulates dendritic spine development. Nature 439, 283-289.
48. Bhattacharyya, S.N., Habermacher, R., Martine, U., Closs, E.I., and Filipowicz, W. (2006) Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125, 1111-1124.
49. Hering, H. and Sheng, M. (2001) Dendritic spines: structure, dynamics and regulation. Nat. Rev. Neurosci. 2, 880-888.
50. Bagni, C. and Greenough, W.T. (2005) From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat. Rev. Neurosci. 6, 376-387.
51. Hoogenraad, C.C., Akhmanova, A., Galjart, N., and De Zeeuw, C.I. (2004) LIMK1 and CLIP-115: linking cytoskeletal defects to Williams syndrome. Bioessays 26, 141-150.
52. Chen, K. and Rajewsky, N. (2006) Natural selection on human microRNA binding sites inferred from SNP data. Nat. Genet. 38, 1452-1456.
53. Abelson, J.F., Kwan, K.Y., O'Roak, B.J., Baek, D.Y., Stillman, A.A., Morgan, T.M., Mathews, C.A., Pauls, D.L., Rasin, M.R., Gunel, M., Davis, N.R., Ercan-Sencicek, A.G., Guez, D.H., Spertus, J.A., Leckman, J.F., Dure, L.S.t., Kurlan, R., Singer, H.S., Gilbert, D.L., Farhi, A., Louvi, A., Lifton, R.P., Sestan, N., and State, M.W. (2005) Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science 310, 317-320.
54. Gubitz, A.K., Feng, W., and Dreyfuss, G. (2004) The SMN complex. Exp. Cell Res. 296, 51-56.
55. Dostie, J., Mourelatos, Z., Yang, M., Sharma, A., and Dreyfuss, G. (2003) Numerous microRNPs in neuronal cells containing novel microRNAs. RNA 9, 180-186.
56. Lugli, G., Larson, J., Martone, M.E., Jones, Y., and Smalheiser, N.R. (2005) Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner. J. Neurochem. 94, 896-905.
57. Flavell, S.W., Cowan, C.W., Kim, T.K., Greer, P.L., Lin, Y., Paradis, S., Griffith, E.C., Hu, L.S., Chen, C., and Greenberg, M.E. (2006) Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science 311, 1008-1012.
58. Dittgen, T., Nimmerjahn, A., Komai, S., Licznerski, P., Waters, J., Margrie, T.W., Helmchen, F., Denk, W., Brecht, M., and Osten, P. (2004) Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo. Proc. Natl. Acad. Sci. U. S. A. 101, 18206-18211.
59. Xia, H., Mao, Q., Paulson, H.L., and Davidson, B.L. (2002) siRNA-mediated gene silencing in vitro and in vivo. Nat. Biotechnol. 20, 1006-1010.
60. Krutzfeldt, J., Rajewsky, N., Braich, R., Rajeev, K.G., Tuschl, T., Manoharan, M., and Stoffel, M. (2005) Silencing of microRNAs in vivo with 'antagomirs'. Nature 438, 685-689.
61. Orom, U.A., Kauppinen, S., and Lund, A.H. (2006) LNA-modified oligonucleotides mediate specific inhibition of microRNA function. Gene 372, 137-141.
62. Kumar, P., Wu, H., McBride, J.L., Jung, K.E., Hee Kim, M., Davidson, B.L., Kyung Lee, S., Shankar, P., and Manjunath, N. (2007) Transvascular delivery of small interfering RNA to the central nervous system. Nature 448(7149), 39-43.