Natural human antibodies to pneumococcus have distinctive molecular characteristics and protect against pneumococcal disease

Clinical and Experimental Immunology

Volumn 151, Issue 1, 2008, Pages 51-60

  Baxendale, H E ^a   Johnson, M ^a   Stephens, R C M ^a   Yuste, J ^b   Klein, N ^a   Brown, J S ^b   Goldblatt, D ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Function; Human; Molecular; Natural antibody; Pneumococcus

Indexed keywords

ANTIGEN; BACTERIAL POLYSACCHARIDE; BLOOD GROUP ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN HEAVY CHAIN V; IMMUNOGLOBULIN M ANTIBODY; INTERMEDIATE FILAMENT PROTEIN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ARTICLE; B LYMPHOCYTE; CELL LINEAGE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MOLECULAR CLONING; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTECTION; PROTEIN BINDING; SEROTYPE; STATISTICAL SIGNIFICANCE; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; AUTOANTIGENS; BASE SEQUENCE; CHI-SQUARE DISTRIBUTION; CROSS REACTIONS; GENES, IMMUNOGLOBULIN; HUMANS; HYBRIDOMAS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STREPTOCOCCUS PNEUMONIAE;

EID: 36849061704     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2007.03535.x     Document Type: Article

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