메뉴 건너뛰기




Volumn 158, Issue 5, 1997, Pages 2477-2489

VHDJH Gene Sequences and Antigen Reactivity of Monoclonal Antibodies Produced by Human B-1 Cells: Evidence for Somatic Selection

Author keywords

[No Author keywords available]

Indexed keywords

CD5 ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; MESSENGER RNA; MONOCLONAL ANTIBODY;

EID: 0031091738     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (57)

References (65)
  • 1
    • 0027447313 scopus 로고
    • B-cell lineages exist in the mouse
    • Herzenberg, L. A., and A. B. Kantor. 1993. B-cell lineages exist in the mouse. Immunol. Today 14:79.
    • (1993) Immunol. Today , vol.14 , pp. 79
    • Herzenberg, L.A.1    Kantor, A.B.2
  • 3
    • 0027955564 scopus 로고
    • CD5 B cells, a fetal B cell lineage
    • Hardy, R. R., and K. Hayakawa. 1994. CD5 B cells, a fetal B cell lineage. Adv. Immunol. 55:297.
    • (1994) Adv. Immunol. , vol.55 , pp. 297
    • Hardy, R.R.1    Hayakawa, K.2
  • 4
    • 0025184095 scopus 로고
    • Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences
    • Feeney, A. J. 1990. Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences. J. Exp. Med. 172:1377.
    • (1990) J. Exp. Med. , vol.172 , pp. 1377
    • Feeney, A.J.1
  • 5
    • 0025335392 scopus 로고
    • H joining: Implications for the joining mechanism and the ontogenetic timing of LY1 B cell and B-CLL progenitor generation
    • H joining: implications for the joining mechanism and the ontogenetic timing of LY1 B cell and B-CLL progenitor generation. EMBO J. 9:2133.
    • (1990) EMBO J. , vol.9 , pp. 2133
    • Gu, H.1    Forster, I.2    Rajewsky, K.3
  • 8
    • 0025905663 scopus 로고
    • Natural autoantibodies: From horror autotoxicus to gnothi seauton
    • Avrameas, S. 1991. Natural autoantibodies: from horror autotoxicus to gnothi seauton. Immunol. Today 12:154.
    • (1991) Immunol. Today , vol.12 , pp. 154
    • Avrameas, S.1
  • 9
    • 0000432770 scopus 로고    scopus 로고
    • Structure-function relation in natural and disease-associated human autoantibodies
    • M. Zanetti and J. D. Capra, eds. Harwood Academic Publishers, Amsterdam
    • Schettino, E. W., Y. Ichiyoshi, and P. Casali. 1996. Structure-function relation in natural and disease-associated human autoantibodies. In The Antibodies. Vol. 2. M. Zanetti and J. D. Capra, eds. Harwood Academic Publishers, Amsterdam, pp. 155-203.
    • (1996) The Antibodies , vol.2 , pp. 155-203
    • Schettino, E.W.1    Ichiyoshi, Y.2    Casali, P.3
  • 10
    • 0002973386 scopus 로고
    • B-1 (CD5) cells
    • A. Coutinho and M. D. Kazatchkine, eds. John Wiley and Sons, New York
    • Casali, P., M. T. Kasaian, and G. Haughton. 1994. B-1 (CD5) cells. In Autoimmunity: Physiology and Disease. A. Coutinho and M. D. Kazatchkine, eds. John Wiley and Sons, New York, pp. 57-88.
    • (1994) Autoimmunity: Physiology and Disease , pp. 57-88
    • Casali, P.1    Kasaian, M.T.2    Haughton, G.3
  • 11
    • 0026542306 scopus 로고
    • The human fetal omentum: A site of B cell generation
    • Solvason, N., X. Chen, F. Shu, and J. F. Kearney. 1992. The human fetal omentum: a site of B cell generation. J. Exp. Med. 175:397.
    • (1992) J. Exp. Med. , vol.175 , pp. 397
    • Solvason, N.1    Chen, X.2    Shu, F.3    Kearney, J.F.4
  • 13
    • 0024844362 scopus 로고
    • The CD5 B cell
    • Kipps, T. J. 1989. The CD5 B cell. Adv. Immunol. 47:117.
    • (1989) Adv. Immunol. , vol.47 , pp. 117
    • Kipps, T.J.1
  • 14
    • 0025781883 scopus 로고
    • Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions
    • Sanz, I. 1991. Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions. J. Immunol. 147:1720.
    • (1991) J. Immunol. , vol.147 , pp. 1720
    • Sanz, I.1
  • 16
    • 0026099589 scopus 로고
    • Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes
    • Yamada, M., R. Wasserman, B, A. Reichard, S. Shane, A. H. Caton, and G. Rovera. 1991. Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes. J. Exp. Med. 173:395.
    • (1991) J. Exp. Med. , vol.173 , pp. 395
    • Yamada, M.1    Wasserman, R.2    Reichard, B.A.3    Shane, S.4    Caton, A.H.5    Rovera, G.6
  • 21
    • 0024238607 scopus 로고
    • Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus: Frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus
    • Nakamura, M., S. E. Burastero, Y. Ueki, J. W. Larrick, A. L. Notkins, and P. Casali. 1988. Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus: frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus. J. Immunol. 141:4165.
    • (1988) J. Immunol. , vol.141 , pp. 4165
    • Nakamura, M.1    Burastero, S.E.2    Ueki, Y.3    Larrick, J.W.4    Notkins, A.L.5    Casali, P.6
  • 24
    • 0029552383 scopus 로고
    • H segment structure of IgG, IgA, and IgM anti-DNA autoantibodies in patients with systemic lupus erythematosus
    • H segment structure of IgG, IgA, and IgM anti-DNA autoantibodies in patients with systemic lupus erythematosus. Ann. NY Acad. Sci. 764:410.
    • (1995) Ann. NY Acad. Sci. , vol.764 , pp. 410
    • Kasaian, M.T.1    Casali, P.2
  • 25
    • 0010550160 scopus 로고
    • Generation of human monoclonal antibody-producing cell lines by Epstein-Barr virus (EBV)-transformation of autoreactive B lymphocytes and by somatic cell hybridization techniques: Application to the analysis of the autoimmune B cell repertoire
    • Nakamura, M., and P. Casali. 1992. Generation of human monoclonal antibody-producing cell lines by Epstein-Barr virus (EBV)-transformation of autoreactive B lymphocytes and by somatic cell hybridization techniques: application to the analysis of the autoimmune B cell repertoire. Immunomethods 1:159.
    • (1992) Immunomethods , vol.1 , pp. 159
    • Nakamura, M.1    Casali, P.2
  • 26
    • 0027199726 scopus 로고
    • + B) cells make somatically hypermutated high affinity IgM rheumatoid factors
    • + B) cells make somatically hypermutated high affinity IgM rheumatoid factors. J. Immunol. 151:473.
    • (1993) J. Immunol. , vol.151 , pp. 473
    • Mantovani, L.1    Wilder, R.L.2    Casali, P.3
  • 27
    • 0028181488 scopus 로고
    • L segments of monoreactive and polyreactive IgA autoantibodies to DNA in patients writh systemic lupus erythematosus
    • L segments of monoreactive and polyreactive IgA autoantibodies to DNA in patients writh systemic lupus erythematosus. J. Immunol. 152:3137.
    • (1994) J. Immunol. , vol.152 , pp. 3137
    • Kasaian, M.T.1    Ikematsu, H.2    Balow, J.E.3    Casali, P.4
  • 28
  • 29
    • 0025184433 scopus 로고
    • The physical organization of the human immunoglobulin heavy chain gene complex
    • Walter, M. A., U. Surti, M. H. Hofker, and D. W. Cox. 1990. The physical organization of the human immunoglobulin heavy chain gene complex. EMBO J. 9:3303.
    • (1990) EMBO J. , vol.9 , pp. 3303
    • Walter, M.A.1    Surti, U.2    Hofker, M.H.3    Cox, D.W.4
  • 33
    • 0019846077 scopus 로고
    • Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes
    • Ravetch, J. V., U. Siebenlist, S. Korsmeyer, T. Waldmann, and P. Leder. 1981. Structure of the human immunoglobulin μ locus: characterization of embryonic and rearranged J and D genes. Cell 27:583.
    • (1981) Cell , vol.27 , pp. 583
    • Ravetch, J.V.1    Siebenlist, U.2    Korsmeyer, S.3    Waldmann, T.4    Leder, P.5
  • 34
    • 0019850678 scopus 로고
    • Human immunoglobulin D segments encoded in tandem mutigenic families
    • Siebenlist, U., J. V. Ravetch, S. Korsmeyer, T. Waldmann, and P. Leder. 1981. Human immunoglobulin D segments encoded in tandem mutigenic families. Nature 294:631.
    • (1981) Nature , vol.294 , pp. 631
    • Siebenlist, U.1    Ravetch, J.V.2    Korsmeyer, S.3    Waldmann, T.4    Leder, P.5
  • 35
    • 0024293529 scopus 로고
    • Organization of human immunoglobulin heavy chain diversity gene loci
    • Ichihara, Y., H. Matsuoka, and Y. Kurosawa. 1988. Organization of human immunoglobulin heavy chain diversity gene loci. EMBO J. 7:4141.
    • (1988) EMBO J. , vol.7 , pp. 4141
    • Ichihara, Y.1    Matsuoka, H.2    Kurosawa, Y.3
  • 38
    • 0028343694 scopus 로고
    • Modular characterization of human Ig heavy chain DIR genes
    • Sanz, I., S.-S. Wang, G. Meneses, and M. Fischbach. 1994. Modular characterization of human Ig heavy chain DIR genes. J. Immunol. 152:3958.
    • (1994) J. Immunol. , vol.152 , pp. 3958
    • Sanz, I.1    Wang, S.-S.2    Meneses, G.3    Fischbach, M.4
  • 39
    • 0023525849 scopus 로고
    • Early restriction of the human antibody repertoire
    • Schroeder, H. W., Jr., J. L. Hillson, and R. M. Perlmutter. 1987. Early restriction of the human antibody repertoire. Science 238:791.
    • (1987) Science , vol.238 , pp. 791
    • Schroeder Jr., H.W.1    Hillson, J.L.2    Perlmutter, R.M.3
  • 41
    • 0028289241 scopus 로고
    • Anatomy of the antibody molecule
    • Padlan, E. A. 1994. Anatomy of the antibody molecule. Mol. Immunol. 31:169.
    • (1994) Mol. Immunol. , vol.31 , pp. 169
    • Padlan, E.A.1
  • 42
    • 0028686184 scopus 로고
    • Antibody structure and the evolution of immunoglobulin V gene segments
    • Kirkham, P. M., and H. W. Schroeder, Jr. 1994. Antibody structure and the evolution of immunoglobulin V gene segments. Semin. Immunol. 6:1.
    • (1994) Semin. Immunol. , vol.6 , pp. 1
    • Kirkham, P.M.1    Schroeder Jr., H.W.2
  • 44
    • 0027932998 scopus 로고
    • H genes are inherently susceptible to amino acid replacement
    • H genes are inherently susceptible to amino acid replacement. Immunol. Today 15:367.
    • (1994) Immunol. Today , vol.15 , pp. 367
    • Chang, B.1    Casali, P.2
  • 46
    • 0023513107 scopus 로고
    • Development of the primary Ab repertoire
    • Alt, F. W., T. K. Blackwell, and G. D. Yancopoulos. 1987. Development of the primary Ab repertoire. Science 238:1079.
    • (1987) Science , vol.238 , pp. 1079
    • Alt, F.W.1    Blackwell, T.K.2    Yancopoulos, G.D.3
  • 47
    • 0027491836 scopus 로고
    • Analysis of Ig H chain gene segment utilization in human fetal liver: Revisiting the "proximal utilization hypothesis."
    • Pascual, V., L. Verkruyse, M. L. Casey. and J. D. Capra. 1993. Analysis of Ig H chain gene segment utilization in human fetal liver: revisiting the "proximal utilization hypothesis." J. Immunol. 151:4164.
    • (1993) J. Immunol. , vol.151 , pp. 4164
    • Pascual, V.1    Verkruyse, L.2    Casey, M.L.3    Capra, J.D.4
  • 48
    • 0002410325 scopus 로고
    • Superantigens and spectrum of unconventional B-cell antigens
    • Silverman, G. J. 1994. Superantigens and spectrum of unconventional B-cell antigens. Immunologist 2:51.
    • (1994) Immunologist , vol.2 , pp. 51
    • Silverman, G.J.1
  • 52
    • 0026555607 scopus 로고
    • Evidence for somatic selection of natural autoantibodies
    • Martin, T., S. F. Duffy, D. A. Carson, and T. J. Kipps. 1992. Evidence for somatic selection of natural autoantibodies. J. Exp. Med. 175:983.
    • (1992) J. Exp. Med. , vol.175 , pp. 983
    • Martin, T.1    Duffy, S.F.2    Carson, D.A.3    Kipps, T.J.4
  • 53
    • 0028307808 scopus 로고
    • Structure-function studies on a polyreactive (natural) autoantibody
    • Martin, T., R. Crouzier, J. C. Weber, T. J. Kipps, and J. L. Pasquali. 1994. Structure-function studies on a polyreactive (natural) autoantibody. J. Immunol. 152:5988.
    • (1994) J. Immunol. , vol.152 , pp. 5988
    • Martin, T.1    Crouzier, R.2    Weber, J.C.3    Kipps, T.J.4    Pasquali, J.L.5
  • 54
    • 0028101448 scopus 로고
    • Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin H and L chain V segments
    • Ichiyoshi, Y., and P. Casali. 1994. Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin H and L chain V segments. J. Exp. Med. 180:885.
    • (1994) J. Exp. Med. , vol.180 , pp. 885
    • Ichiyoshi, Y.1    Casali, P.2
  • 55
    • 0028837355 scopus 로고
    • A human anti-insulin IgG autoantibody apparently arises through clonal selection from an insulin-specific "germline" natural Ab template
    • Ichiyoshi, Y., M. Zhou, and P. Casali. 1995. A human anti-insulin IgG autoantibody apparently arises through clonal selection from an insulin-specific "germline" natural Ab template. J. Immunol. 154:226.
    • (1995) J. Immunol. , vol.154 , pp. 226
    • Ichiyoshi, Y.1    Zhou, M.2    Casali, P.3
  • 56
    • 0029061664 scopus 로고
    • H chain variable region, L chain variable region, and H chain CDR3 influences on the mono- And polyreactivity and on the affinity of human monoclonal rheumatoid factors
    • Crouzier, R., T. Martin, and J. L. Pasquali. 1995. H chain variable region, L chain variable region, and H chain CDR3 influences on the mono-and polyreactivity and on the affinity of human monoclonal rheumatoid factors. J. Immunol. 154:4526.
    • (1995) J. Immunol. , vol.154 , pp. 4526
    • Crouzier, R.1    Martin, T.2    Pasquali, J.L.3
  • 57
    • 0027788044 scopus 로고
    • L regions of polyreactive and monoreactive human natural antibodies to HIV-1 and E. coli β-galactosidase
    • L regions of polyreactive and monoreactive human natural antibodies to HIV-1 and E. coli β-galactosidase. Int. Immunol. 5:1523.
    • (1993) Int. Immunol. , vol.5 , pp. 1523
    • Harindranath, N.1    Ikematsu, H.2    Notkins, A.L.3    Casali, P.4
  • 60
    • 0028354220 scopus 로고
    • Development of B-1 cells: Segregation of phosphatidyl choline-specific B cells to the B-1 population occurs after immunoglobulin gene expression
    • Arnold, L. W., C. A. Pennell, S. K. McCray, and S. H. Clarke. 1994. Development of B-1 cells: segregation of phosphatidyl choline-specific B cells to the B-1 population occurs after immunoglobulin gene expression. J. Exp. Med. 179:1585.
    • (1994) J. Exp. Med. , vol.179 , pp. 1585
    • Arnold, L.W.1    Pennell, C.A.2    McCray, S.K.3    Clarke, S.H.4
  • 61
    • 0028942191 scopus 로고
    • B-cell activation by crosslinking of surface IgM or ligation of CD40 involves alternative signal pathways and results in different B-cell phenotypes
    • Wortis, H. H., M. Teutsch, M. Higer, J. Zheng, and D. C. Parker. 1995. B-cell activation by crosslinking of surface IgM or ligation of CD40 involves alternative signal pathways and results in different B-cell phenotypes. Proc. Natl. Acad. Sci. USA 92:3348.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3348
    • Wortis, H.H.1    Teutsch, M.2    Higer, M.3    Zheng, J.4    Parker, D.C.5
  • 63
    • 0026518919 scopus 로고
    • Immunoglobulin light chain variable region gene sequences for human antibodies to Haemophilus influenzae type b capsular polysaccharide are dominated by a limited number of V kappa and V lambda segments and VJ combinations
    • Adderson, E. E., P. G. Shackelford, R. A. Insel, A. Quinn, P. M. Wilson, and W. L. Carroll. 1992. Immunoglobulin light chain variable region gene sequences for human antibodies to Haemophilus influenzae type b capsular polysaccharide are dominated by a limited number of V kappa and V lambda segments and VJ combinations. J. Clin. Invest. 89:729.
    • (1992) J. Clin. Invest. , vol.89 , pp. 729
    • Adderson, E.E.1    Shackelford, P.G.2    Insel, R.A.3    Quinn, A.4    Wilson, P.M.5    Carroll, W.L.6
  • 64
    • 0027216150 scopus 로고
    • H usage ana VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide: Nucleotide sequences of monospecific anti-HaemophiluS antibodies and polyspecific antibodies cross-reacting with self antigens
    • H usage ana VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide: nucleotide sequences of monospecific anti-HaemophiluS antibodies and polyspecific antibodies cross-reacting with self antigens. J. Clin. Invest. 91:2734.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2734
    • Adderson, E.E.1    Shackelford, P.G.2    Quinn, A.3    Wilson, P.M.4    Cunninghan, M.W.5    Insel, R.A.6    Carroll, W.L.7
  • 65
    • 0025188124 scopus 로고
    • Regulation of magnitude of antibody-response to bacterial polysaccharide antigens by thymus-derived lymphocytes
    • Baker, P. J. 1990. Regulation of magnitude of antibody-response to bacterial polysaccharide antigens by thymus-derived lymphocytes. Infect. Immun. 58:3465.
    • (1990) Infect. Immun. , vol.58 , pp. 3465
    • Baker, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.