The dual function of the splenic marginal zone: Essential for initiation of anti-TI-2 responses but also vital in the general first-line defense against blood-borne antigens

Clinical and Experimental Immunology

Volumn 130, Issue 1, 2002, Pages 4-11

  Zandvoort, A ^a   Timens, W ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

B cells; Memory; Splenic marginal zone; T cell independent type 2 antigens pneumococcal polysaccharides

Indexed keywords

ANTIGEN; B LYMPHOCYTE RECEPTOR; COMPLEMENT COMPONENT C2; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3D RECEPTOR; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M; OPSONIN;

ANTIBODY BLOOD LEVEL; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; BACTERIAL INFECTION; BINDING AFFINITY; BIODIVERSITY; BLOOD; BLOOD FLOW; CELL ACTIVATION; CELL ACTIVITY; DENDRITIC CELL; HUMAN; HUMORAL IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; MICROENVIRONMENT; NONHUMAN; OPSONIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVIEW; SPLEEN; SPLEEN CELL; T LYMPHOCYTE;

ADULT; ANIMALS; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, CD; ANTIGENS, CD19; ANTIGENS, DIFFERENTIATION; ANTIGENS, T-INDEPENDENT; B-LYMPHOCYTE SUBSETS; BLOOD-BORNE PATHOGENS; COMPLEMENT C3D; DISEASE SUSCEPTIBILITY; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN M; IMMUNOLOGIC MEMORY; INFANT; LYMPHOCYTE ACTIVATION; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; MICE, NUDE; RECEPTORS, COMPLEMENT 3D; SPLEEN; SPLENECTOMY;

EID: 0036380003     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2002.01953.x     Document Type: Review

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