-
1
-
-
0021248888
-
Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats
-
Clark, J. T.; Kalra, P. S.; Crowley, W. R.; Kalra, S. P. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology, 1984, 115, 427-429.
-
(1984)
Endocrinology
, vol.115
, pp. 427-429
-
-
Clark, J.T.1
Kalra, P.S.2
Crowley, W.R.3
Kalra, S.P.4
-
2
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman, J. M.; Halaas, J. L. Leptin and the regulation of body weight in mammals. Nature, 1998, 395, 763-770.
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
3
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra, S. P.; Dube, M. G.; Pu, S.; Xu, B.; Horvath, T. L.; Kalra, P. S. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr. Rev., 1999, 20, 68-100.
-
(1999)
Endocr. Rev
, vol.20
, pp. 68-100
-
-
Kalra, S.P.1
Dube, M.G.2
Pu, S.3
Xu, B.4
Horvath, T.L.5
Kalra, P.S.6
-
4
-
-
0037471351
-
Rhythmic, reciprocal ghrelin and lentin signaling: New insight in the development of obesity
-
Kalra, S. P.; Bagnasco, M.; Otukonyong, E. E.; Dube, M. G.; Kalra, P. S. Rhythmic, reciprocal ghrelin and lentin signaling: new insight in the development of obesity. Regul. Pept., 2003, 111, 1-11.
-
(2003)
Regul. Pept
, vol.111
, pp. 1-11
-
-
Kalra, S.P.1
Bagnasco, M.2
Otukonyong, E.E.3
Dube, M.G.4
Kalra, P.S.5
-
5
-
-
33845875966
-
Gut hormones and the regulation of energy homeostasis
-
Murphy, K. G.; Bloom, S. R. Gut hormones and the regulation of energy homeostasis. Nature, 2006, 444, 854-859.
-
(2006)
Nature
, vol.444
, pp. 854-859
-
-
Murphy, K.G.1
Bloom, S.R.2
-
6
-
-
33845864967
-
Adipocytes as regulators of energy balance and glucose homeostasis
-
Rosen, E. D.; Spiegelman, B. M. Adipocytes as regulators of energy balance and glucose homeostasis. Nature, 2006, 444, 847-853.
-
(2006)
Nature
, vol.444
, pp. 847-853
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
7
-
-
17144385790
-
Excess deaths associated with underweight, overweight, and obesity
-
Flegal, K. M.; Graubard, B. I.; Williamson, D. F.; Gail, M. H. Excess deaths associated with underweight, overweight, and obesity. JAMA, 2005, 293, 1861-1867.
-
(2005)
JAMA
, vol.293
, pp. 1861-1867
-
-
Flegal, K.M.1
Graubard, B.I.2
Williamson, D.F.3
Gail, M.H.4
-
8
-
-
33845886915
-
Abdominal obesity and metabolic syndrome
-
Despres, J. P.; Lemieux, I. Abdominal obesity and metabolic syndrome. Nature, 2006, 444, 881-887.
-
(2006)
Nature
, vol.444
, pp. 881-887
-
-
Despres, J.P.1
Lemieux, I.2
-
9
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn, S. E.; Hull, R. L.; Utzschneider, K. M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature, 2006, 444, 840-846.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
10
-
-
0033305646
-
Current and potential drugs for treatment of obesity
-
Bray, G. A.; Greenway, F. L. Current and potential drugs for treatment of obesity. Endocr. Rev., 1999, 20, 805-875.
-
(1999)
Endocr. Rev
, vol.20
, pp. 805-875
-
-
Bray, G.A.1
Greenway, F.L.2
-
11
-
-
0035836667
-
Circumventing leptin resistance for weight control
-
Kalra, S. P. Circumventing leptin resistance for weight control. Proc. Natl. Acad. Sci. USA, 2001, 98, 4279-4281.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4279-4281
-
-
Kalra, S.P.1
-
12
-
-
0035513839
-
Viral vectors as probes to decipher brain circuitry for weight control
-
Kalra, S. P.; Kalra, P. S. Viral vectors as probes to decipher brain circuitry for weight control. Trends Endocrinol. Metab., 2001, 12, 377-378.
-
(2001)
Trends Endocrinol. Metab
, vol.12
, pp. 377-378
-
-
Kalra, S.P.1
Kalra, P.S.2
-
13
-
-
0036461347
-
Obesity and Metabolic Syndrome: Longterm benefits of central leptin gene therapy
-
Prous, J. R, Ed, Prous Science, Barcelona, Spain
-
Kalra, P. S.; Kalra, S. P. Obesity and Metabolic Syndrome: Longterm benefits of central leptin gene therapy. In: Prous, J. R. (Ed.), Drugs of Today, vol.38. Prous Science, Barcelona, Spain, 2002, pp. 745-757.
-
(2002)
Drugs of Today
, vol.38
, pp. 745-757
-
-
Kalra, P.S.1
Kalra, S.P.2
-
14
-
-
0041733148
-
Keeping obesity and metabolic syndrome at bay with central leptin and cytokine gene therapy
-
Hamilton, I, Ed, Bentham Science Publishers Ltd, San Francisco, CA
-
Kalra, S. P.; Kalra, P. S. Keeping obesity and metabolic syndrome at bay with central leptin and cytokine gene therapy. In: Hamilton, I. (Ed.), Current Medicinal Chemistry - Central Nervous System Agent; vol.3. Bentham Science Publishers Ltd., San Francisco, CA, 2003, pp. 189-199.
-
(2003)
Current Medicinal Chemistry - Central Nervous System Agent
, vol.3
, pp. 189-199
-
-
Kalra, S.P.1
Kalra, P.S.2
-
15
-
-
2442424380
-
Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
-
Arvanitakis, Z.; Wilson, R. S.; Bienias, J. L.; Evans, D. A.; Bennett, D. A. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch. Neurol., 2004, 61, 661-666.
-
(2004)
Arch. Neurol
, vol.61
, pp. 661-666
-
-
Arvanitakis, Z.1
Wilson, R.S.2
Bienias, J.L.3
Evans, D.A.4
Bennett, D.A.5
-
16
-
-
33749487087
-
Role of leptin in the cardiovascular and endocrine complications of metabolic syndrome
-
Correia, M. L. G.; Rahmouni, K. Role of leptin in the cardiovascular and endocrine complications of metabolic syndrome. Diabet. Obes. Metabol., 2006, 8, 603-610.
-
(2006)
Diabet. Obes. Metabol
, vol.8
, pp. 603-610
-
-
Correia, M.L.G.1
Rahmouni, K.2
-
17
-
-
0024159787
-
Continuous intraven-tricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats; effects of adrenalectomy and cholecystokinin
-
Kalra, S. P.; Dube, M. G.; Kalra, P. S. Continuous intraven-tricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats; effects of adrenalectomy and cholecystokinin. Peptides, 1988, 9, 723-728.
-
(1988)
Peptides
, vol.9
, pp. 723-728
-
-
Kalra, S.P.1
Dube, M.G.2
Kalra, P.S.3
-
18
-
-
0242660829
-
-
Kalra, S. P.; Kalra, P. S. Neuropeptide Y: a physiological orexigen modulated by the feedback action of ghrelin and leptin. Endocrine, 2003, 22, 49-55.
-
Kalra, S. P.; Kalra, P. S. Neuropeptide Y: a physiological orexigen modulated by the feedback action of ghrelin and leptin. Endocrine, 2003, 22, 49-55.
-
-
-
-
19
-
-
84882908958
-
-
Kalra, S. P.; Kalra, P. S. Neuropeptide Y: a conductor of the appetite-regulating orchestra in the hypothalamus. In: Kastin, A. J. [Ed.], The Handbook of Biologically Active Peptides, In Press. Academic Press, Burlington, MA. 2006.
-
Kalra, S. P.; Kalra, P. S. Neuropeptide Y: a conductor of the appetite-regulating orchestra in the hypothalamus. In: Kastin, A. J. [Ed.], The Handbook of Biologically Active Peptides, vol.In Press. Academic Press, Burlington, MA. 2006.
-
-
-
-
20
-
-
0025721025
-
Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food
-
Kalra, S. P.; Dube, M. G.; Sahu, A.; Phelps, C. P.; Kalra, P. S. Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food. Proc. Natl. Acad., Sci. USA, 1991, 88, 10931-10935.
-
(1991)
Proc. Natl. Acad., Sci. USA
, vol.88
, pp. 10931-10935
-
-
Kalra, S.P.1
Dube, M.G.2
Sahu, A.3
Phelps, C.P.4
Kalra, P.S.5
-
21
-
-
27344431720
-
-
Luquet, S.; Perez, F. A.; Hnasko, T. S.; Palmiter, R. D. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science, 2005, 310, 683-685.
-
Luquet, S.; Perez, F. A.; Hnasko, T. S.; Palmiter, R. D. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science, 2005, 310, 683-685.
-
-
-
-
22
-
-
0037502842
-
NPY ablation in C57BL/6 mice leads to mild obesity and to an impaired refeeding response to fasting
-
Segal-Lieberman, G.; Trombly, D. J.; Juthani, V.; Wang, X.; Maratos-Flier, E. NPY ablation in C57BL/6 mice leads to mild obesity and to an impaired refeeding response to fasting. Am. J Physiol. Endocrinol. Metab., 2003, 284, E1131-1139.
-
(2003)
Am. J Physiol. Endocrinol. Metab
, vol.284
-
-
Segal-Lieberman, G.1
Trombly, D.J.2
Juthani, V.3
Wang, X.4
Maratos-Flier, E.5
-
23
-
-
3042640662
-
Neuropeptide Y is required for hyperphagic feeding in response to neuroglucopenia
-
Sindelar, D. K.; Ste Marie, L.; Miura, G. I.; Palmiter, R. D.; McMinn, J. E.; Morton, G. J.; Schwartz, M. W. Neuropeptide Y is required for hyperphagic feeding in response to neuroglucopenia. Endocrinology, 2004, 145, 3363-3368.
-
(2004)
Endocrinology
, vol.145
, pp. 3363-3368
-
-
Sindelar, D.K.1
Ste Marie, L.2
Miura, G.I.3
Palmiter, R.D.4
McMinn, J.E.5
Morton, G.J.6
Schwartz, M.W.7
-
24
-
-
12344310130
-
AAV mediated expression of anti-sense neuropeptide Y cRNA in the arcuate nucleus of rats results in decreased weight gain and food intake
-
Gardiner, J. V.; Kong, W. M.; Ward, H.; Murphy, K. G.; Dhillo, W. S.; Bloom, S. R. AAV mediated expression of anti-sense neuropeptide Y cRNA in the arcuate nucleus of rats results in decreased weight gain and food intake. Biochem. Biophys. Res. Commun., 2005, 327, 1088-1093.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.327
, pp. 1088-1093
-
-
Gardiner, J.V.1
Kong, W.M.2
Ward, H.3
Murphy, K.G.4
Dhillo, W.S.5
Bloom, S.R.6
-
25
-
-
0034674684
-
Behavioral characteri-zation of neuropeptide Y knockout mice
-
Bannon, A. W.; Seda, J.; Carmouche, M.; Francis, J. M.; Norman, M. H.; Karbon, B.; McCaleb, M. L. Behavioral characteri-zation of neuropeptide Y knockout mice. Brain Res., 2000, 868, 79-87.
-
(2000)
Brain Res
, vol.868
, pp. 79-87
-
-
Bannon, A.W.1
Seda, J.2
Carmouche, M.3
Francis, J.M.4
Norman, M.H.5
Karbon, B.6
McCaleb, M.L.7
-
26
-
-
0028335412
-
Evidence that nouropeptide Y is a physiological signal for normal food intake
-
Dube, M. G.; Xu, B.; Crowley, W. R.; Kalra, P. S.; Kalra, S. P. Evidence that nouropeptide Y is a physiological signal for normal food intake. Brain Res., 1994, 646, 341-344.
-
(1994)
Brain Res
, vol.646
, pp. 341-344
-
-
Dube, M.G.1
Xu, B.2
Crowley, W.R.3
Kalra, P.S.4
Kalra, S.P.5
-
27
-
-
0030272305
-
Nutritional infertility: The role of the interconnected hypothalamic neuropeptide Y-galanin-opioid network
-
Kalra, S. P.; Kalra, P. S. Nutritional infertility: the role of the interconnected hypothalamic neuropeptide Y-galanin-opioid network. Front Neuroendocrinol., 1996, 17, 371-401.
-
(1996)
Front Neuroendocrinol
, vol.17
, pp. 371-401
-
-
Kalra, S.P.1
Kalra, P.S.2
-
28
-
-
2642576000
-
Melanocortin 4 receptor-mediated hyperphagia and activation of neuropeptide Y expression in the dorsomedial hypothalamus during lactation
-
Chen, P.; Williams, S. M.; Grove, K. L.; Smith, M. S. Melanocortin 4 receptor-mediated hyperphagia and activation of neuropeptide Y expression in the dorsomedial hypothalamus during lactation. J. Neurosci., 2004, 24, 5091-5100.
-
(2004)
J. Neurosci
, vol.24
, pp. 5091-5100
-
-
Chen, P.1
Williams, S.M.2
Grove, K.L.3
Smith, M.S.4
-
29
-
-
33746880281
-
The hypothalamic paraventricular nucleus is not essential for orexigenic NPY or anorexigenic melanocortin action
-
Dube, M. G.; Kalra, S. P.; Kalra, P. S. The hypothalamic paraventricular nucleus is not essential for orexigenic NPY or anorexigenic melanocortin action. Peptides, 2006, 27, 2239-2248.
-
(2006)
Peptides
, vol.27
, pp. 2239-2248
-
-
Dube, M.G.1
Kalra, S.P.2
Kalra, P.S.3
-
30
-
-
0033573760
-
Disruption in neuropeptide Y and leptin signaling in obese ventromedial hypothalamic-lesioned rats
-
Dube, M. G.; Xu, B.; Kalra, P. S.; Sninsky, C. A.; Kalra, S. P. Disruption in neuropeptide Y and leptin signaling in obese ventromedial hypothalamic-lesioned rats. Brain Res., 1999, 816, 38-46.
-
(1999)
Brain Res
, vol.816
, pp. 38-46
-
-
Dube, M.G.1
Xu, B.2
Kalra, P.S.3
Sninsky, C.A.4
Kalra, S.P.5
-
31
-
-
33846630951
-
Low abundance of NPY in the hypothalamus can produce hyperphagia and obesity
-
doi:10.1016/j.peptides.2006.10.017
-
Dube, M. G.; Kalra, S. P.; Kalra, P. S. Low abundance of NPY in the hypothalamus can produce hyperphagia and obesity. Peptides. 2007, doi:10.1016/j.peptides.2006.10.017.
-
(2007)
Peptides
-
-
Dube, M.G.1
Kalra, S.P.2
Kalra, P.S.3
-
32
-
-
33044493099
-
Permanent interruption of information flow between hypothalamus and hindbrain produces obesity accompanied by a selective dark-phase hyperphagia and hyperinsulinemia
-
New Orleans, LA. Society for Neuroscience, Abs #831.837
-
Pu, S.; Dube, M. G.; Kalra, S. P.; Kalra, P. S. Permanent interruption of information flow between hypothalamus and hindbrain produces obesity accompanied by a selective dark-phase hyperphagia and hyperinsulinemia. Proceedings of the 33rd Annual Society for Neuroscience Meeting, New Orleans, LA. Society for Neuroscience, 2003, pp. W-33, Abs #831.837.
-
(2003)
Proceedings of the 33rd Annual Society for Neuroscience Meeting
-
-
Pu, S.1
Dube, M.G.2
Kalra, S.P.3
Kalra, P.S.4
-
33
-
-
0027349189
-
Ageing of theneuropep-tidergic signals in rats
-
Kalra, S. P.; Sahu, A.; Kalra, P. S. Ageing of theneuropep-tidergic signals in rats. J. Reprod. Fertil. Suppl., 1993, 46, 11-19.
-
(1993)
J. Reprod. Fertil. Suppl
, vol.46
, pp. 11-19
-
-
Kalra, S.P.1
Sahu, A.2
Kalra, P.S.3
-
34
-
-
0033278997
-
Daily changes in hypothalamic gene expression of neuropeptide Y, galanin, proopiomelanocortin, and adipocyte leptin gene expres-sion and secretion: Effects of food restriction
-
Xu, B.; Kalra, P. S.; Farmerie, W. G.; Kalra, S. P. Daily changes in hypothalamic gene expression of neuropeptide Y, galanin, proopiomelanocortin, and adipocyte leptin gene expres-sion and secretion: effects of food restriction. Endocrinology, 1999, 140, 2868-2875.
-
(1999)
Endocrinology
, vol.140
, pp. 2868-2875
-
-
Xu, B.1
Kalra, P.S.2
Farmerie, W.G.3
Kalra, S.P.4
-
35
-
-
0035091692
-
The mPVN mediates blockade of NPY-induced feeding by a Y5 receptor antagonist: A c-FOS analysis
-
Yokosuka, Mc, Dube, M. G.; Kalra, P. S.; Kalra, S. P. The mPVN mediates blockade of NPY-induced feeding by a Y5 receptor antagonist: a c-FOS analysis. Peptides, 2001, 22, 507-514.
-
(2001)
Peptides
, vol.22
, pp. 507-514
-
-
Yokosuka, M.1
Dube, M.G.2
Kalra, P.S.3
Kalra, S.P.4
-
36
-
-
0033305207
-
Inhibition of neuropeptide Y [NPY]-induced feeding and c-Fos response in magnocellular paraventricular nucleus by a NPY receptor antagonist: A site of NPY action
-
Yokosuka, M.; Kalra, P. S.; Kalra, S. P. Inhibition of neuropeptide Y [NPY]-induced feeding and c-Fos response in magnocellular paraventricular nucleus by a NPY receptor antagonist: a site of NPY action. Endocrinology, 1999, 140, 4494-4500.
-
(1999)
Endocrinology
, vol.140
, pp. 4494-4500
-
-
Yokosuka, M.1
Kalra, P.S.2
Kalra, S.P.3
-
37
-
-
0032096532
-
Neural substrates for leptin and neuropeptide Y [NPY] interaction: Hypothalamic sites associated with inhibition of NPY-induced food intake
-
Yokosuka, M.; Xu, B.; Pu, S.; Kalra, P. S.; Kalra, S. P. Neural substrates for leptin and neuropeptide Y [NPY] interaction: hypothalamic sites associated with inhibition of NPY-induced food intake. Physiol. Behav., 1998, 64, 331-338.
-
(1998)
Physiol. Behav
, vol.64
, pp. 331-338
-
-
Yokosuka, M.1
Xu, B.2
Pu, S.3
Kalra, P.S.4
Kalra, S.P.5
-
38
-
-
0031972988
-
Neuropeptide Y [NPY] Y, receptor mRNA is upregulated in association with transient hyperphagia and body weight gain: Evidence for a hypothalamic site for concurrent development of leptin resistance
-
Kalra, P. S.; Dube, M. G.; Xu, B.; Farmerie, W. G.; Kalra, S. P. Neuropeptide Y [NPY] Y, receptor mRNA is upregulated in association with transient hyperphagia and body weight gain: evidence for a hypothalamic site for concurrent development of leptin resistance. J. Neuroendocrinol., 1998, 10, 43-49.
-
(1998)
J. Neuroendocrinol
, vol.10
, pp. 43-49
-
-
Kalra, P.S.1
Dube, M.G.2
Xu, B.3
Farmerie, W.G.4
Kalra, S.P.5
-
39
-
-
0031592881
-
Increased receptor sensitivity to neuropeptide Y in the hypothalamus may underlie transient hyperphagia and body weight gain
-
Kalra, P. S.; Dube, M. G.; Xu, B.; Kalra, S. P. Increased receptor sensitivity to neuropeptide Y in the hypothalamus may underlie transient hyperphagia and body weight gain. Regul. Pept., 1997, 72, 121-130.
-
(1997)
Regul. Pept
, vol.72
, pp. 121-130
-
-
Kalra, P.S.1
Dube, M.G.2
Xu, B.3
Kalra, S.P.4
-
40
-
-
0028116136
-
c-fos expression in the rat brain following central administration of neuropeptide Y and effects of food consumption
-
Li, B. H.; Xu, B.; Rowland, N. E.; Kalra, S. P. c-fos expression in the rat brain following central administration of neuropeptide Y and effects of food consumption. Brain Res., 1994, 665, 277-284.
-
(1994)
Brain Res
, vol.665
, pp. 277-284
-
-
Li, B.H.1
Xu, B.2
Rowland, N.E.3
Kalra, S.P.4
-
41
-
-
0035133586
-
Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin
-
Asakawa, A.; Inui, A.; Kaga, T.; Yuzuriha, H.; Nagata, T.; Ueno, N.; Makino, S.; Fujimiya, M.; Niijima, A.; Fujino, M. A.; Kasuga, M. Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology, 2001, 120, 337-345.
-
(2001)
Gastroenterology
, vol.120
, pp. 337-345
-
-
Asakawa, A.1
Inui, A.2
Kaga, T.3
Yuzuriha, H.4
Nagata, T.5
Ueno, N.6
Makino, S.7
Fujimiya, M.8
Niijima, A.9
Fujino, M.A.10
Kasuga, M.11
-
42
-
-
2342658029
-
Circulating triglycerides impact on orexigenic peptides and neuronal activity in hypothalamus
-
Chang, G. Q.; Karatayev, O.; Davydova, Z.; Leibowitz, S. F. Circulating triglycerides impact on orexigenic peptides and neuronal activity in hypothalamus. Endocrinology, 2004, 145, 3904-3912.
-
(2004)
Endocrinology
, vol.145
, pp. 3904-3912
-
-
Chang, G.Q.1
Karatayev, O.2
Davydova, Z.3
Leibowitz, S.F.4
-
44
-
-
0035143816
-
Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway
-
Shintani, M.; Ogawa, Y.; Ebihara, K.; Aizawa-Abe, M.; Miyanaga, F.; Takaya, K.; Hayashi, T.; Inoue, G.; Hosoda, K.; Kojima, M.; Kangawa, K.; Nakao, K. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway. Diabetes, 2001, 50, 227-232.
-
(2001)
Diabetes
, vol.50
, pp. 227-232
-
-
Shintani, M.1
Ogawa, Y.2
Ebihara, K.3
Aizawa-Abe, M.4
Miyanaga, F.5
Takaya, K.6
Hayashi, T.7
Inoue, G.8
Hosoda, K.9
Kojima, M.10
Kangawa, K.11
Nakao, K.12
-
45
-
-
14544279805
-
Longevity, lipotoxicity and leptin: The adipocyte defense against feasting and famine
-
Unger, R. H. Longevity, lipotoxicity and leptin: the adipocyte defense against feasting and famine. Biochimie, 2005, 87, 57-64.
-
(2005)
Biochimie
, vol.87
, pp. 57-64
-
-
Unger, R.H.1
-
46
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi, T.; Kamon, J.; Waki, H.; Terauchi, Y.; Kubota, N.; Hara, K.; Mori, Y.; Ide, T.; Murakami, K.; Tsuboyama-Kasaoka, N.; Ezaki, O.; Akanuma, Y.; Gavrilova, O.; Vinson, C.; Reitman, M. L.; Kagechika, H.; Shudo, K.; Yoda, M.; Nakano, Y.; Tobe, K.; Nagai, R.; Kimura, S.; Tomita, M.; Froguel, P.; Kadowaki, T. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med., 2001, 7, 941-946.
-
(2001)
Nat. Med
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Terauchi, Y.4
Kubota, N.5
Hara, K.6
Mori, Y.7
Ide, T.8
Murakami, K.9
Tsuboyama-Kasaoka, N.10
Ezaki, O.11
Akanuma, Y.12
Gavrilova, O.13
Vinson, C.14
Reitman, M.L.15
Kagechika, H.16
Shudo, K.17
Yoda, M.18
Nakano, Y.19
Tobe, K.20
Nagai, R.21
Kimura, S.22
Tomita, M.23
Froguel, P.24
Kadowaki, T.25
more..
-
47
-
-
0036511213
-
ACRP30/adiponectin: An adipokine regulating glucose and lipid metabolism
-
Berg, A. H.; Combs, T. P.; Scherer, P. E. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol. Metab., 2002, 13, 84-89.
-
(2002)
Trends Endocrinol. Metab
, vol.13
, pp. 84-89
-
-
Berg, A.H.1
Combs, T.P.2
Scherer, P.E.3
-
48
-
-
0028318098
-
Anorectic effects of estrogen may be mediated by decreased neuropeptide- Y release in the hypothalamic paraventricular nucleus
-
Bonavera, J. J.; Dube, M. G.; Kalra, P. S.; Kalra, S. P. Anorectic effects of estrogen may be mediated by decreased neuropeptide- Y release in the hypothalamic paraventricular nucleus. Endocrinology, 1994, 34, 2367-2370.
-
(1994)
Endocrinology
, vol.34
, pp. 2367-2370
-
-
Bonavera, J.J.1
Dube, M.G.2
Kalra, P.S.3
Kalra, S.P.4
-
49
-
-
0034714041
-
-
Pu, S.; Dube, M. G.; Kalra, P. S.; P., K. S. Regulation of leptin secretion: Effects of aging on daily patterns of serum leptin and food consumption. Regul. Pept., 2000, 92, 107-111.
-
Pu, S.; Dube, M. G.; Kalra, P. S.; P., K. S. Regulation of leptin secretion: Effects of aging on daily patterns of serum leptin and food consumption. Regul. Pept., 2000, 92, 107-111.
-
-
-
-
50
-
-
0026737862
-
Hypothalamic neuropeptide Y gene expression in rats on scheduled feeding regimen
-
Sahu, A.; White, J. D.; Kalra, P. S.; Kalra, S. P. Hypothalamic neuropeptide Y gene expression in rats on scheduled feeding regimen. Brain Res. Mol. Brain Res., 1992, 15, 15-18.
-
(1992)
Brain Res. Mol. Brain Res
, vol.15
, pp. 15-18
-
-
Sahu, A.1
White, J.D.2
Kalra, P.S.3
Kalra, S.P.4
-
51
-
-
4344675633
-
Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy
-
Ueno, N.; Dube, M. G,; Inui, A.; Kalra, P. S.; Kalra, S. P. Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy. Endocrinology, 2004, 145, 4176-4184.
-
(2004)
Endocrinology
, vol.145
, pp. 4176-4184
-
-
Ueno, N.1
Dube, M.G.2
Inui, A.3
Kalra, P.S.4
Kalra, S.P.5
-
52
-
-
33746886648
-
Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice
-
Ueno, N.; Inui, A.; Kalra, S. P.; Kalra, P. S. Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice. Peptides, 2006, 27, 2332-2342.
-
(2006)
Peptides
, vol.27
, pp. 2332-2342
-
-
Ueno, N.1
Inui, A.2
Kalra, S.P.3
Kalra, P.S.4
-
53
-
-
18344376775
-
Stimulation of appetite by ghrelin is regulated by leptin restraint: Peripheral and central sites of action
-
Kalra, S. P.; Ueno, N.; Kalra, P. S. Stimulation of appetite by ghrelin is regulated by leptin restraint: peripheral and central sites of action. J. Nutr., 2005, 135, 1331-1335.
-
(2005)
J. Nutr
, vol.135
, pp. 1331-1335
-
-
Kalra, S.P.1
Ueno, N.2
Kalra, P.S.3
-
54
-
-
4344595580
-
NPY and Cohorts in Regulating Appetite, Obesity and Metabolic Syndrome: Beneficial Effects of Gene Therapy
-
Kalra, S. P.; Kalra, P. S. NPY and Cohorts in Regulating Appetite, Obesity and Metabolic Syndrome: Beneficial Effects of Gene Therapy. Neuropeptides, 2004, 38, 201-211.
-
(2004)
Neuropeptides
, vol.38
, pp. 201-211
-
-
Kalra, S.P.1
Kalra, P.S.2
-
55
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
Farooqi, I. S.; Matarese, G.; Lord, G. M.; Keogh, J. M.; Lawrence, E.; Agwu, C.; Sanna, V.; Jebb, S. A.; Pema, F.; Fontana, S.; Lechler, R. I.; DePaoli, A. M.; O'Rahilly, zS. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J. Clin. Invest., 2002, 110, 1093-1103.
-
(2002)
J. Clin. Invest
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
Keogh, J.M.4
Lawrence, E.5
Agwu, C.6
Sanna, V.7
Jebb, S.A.8
Pema, F.9
Fontana, S.10
Lechler, R.I.11
DePaoli, A.M.12
O'Rahilly13
zS14
-
57
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague, C. T.; Farooqi, I. S.; Whitehead, J. P.; Soos, M. A.; Rau, H.; Wareham, N. J.; Sewter, C. P.; Digby, J. E.; Mohammed, S. N.; Hurst, J. A.; Cheetham, C. H.; Earley,.A. R.; Barnett, A. H.; Prins, J. B.; O'Rabilly, S. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature, 1997, 387, 903-908.
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
Sewter, C.P.7
Digby, J.E.8
Mohammed, S.N.9
Hurst, J.A.10
Cheetham, C.H.11
Earley, A.R.12
Barnett, A.H.13
Prins, J.B.14
O'Rabilly, S.15
-
58
-
-
0036263327
-
Central leptin gene therapy blocks high fat diet-induced weight gain, hyperleptinemia and hyperinsulinemia: Effects on serum ghrelin levels
-
Dube, M. G.; Beretta, E.; Dhillon, H.; Ueno, N.; Kalra, P. S.; Kalra, S. P. Central leptin gene therapy blocks high fat diet-induced weight gain, hyperleptinemia and hyperinsulinemia: effects on serum ghrelin levels. Diabetes, 2002, 51, 1729-1736.
-
(2002)
Diabetes
, vol.51
, pp. 1729-1736
-
-
Dube, M.G.1
Beretta, E.2
Dhillon, H.3
Ueno, N.4
Kalra, P.S.5
Kalra, S.P.6
-
59
-
-
0032763709
-
Impaired transport of leptin across the blood-brain barrier in obesity
-
Banks, W. A.; DiPalma, C. R. and Farrell, C. L. Impaired transport of leptin across the blood-brain barrier in obesity. Peptides, 1999, 20, 1341-1345.
-
(1999)
Peptides
, vol.20
, pp. 1341-1345
-
-
Banks, W.A.1
DiPalma, C.R.2
Farrell, C.L.3
-
60
-
-
0029864416
-
-
Banks, W. A.; Kastin, A. J.; Huang, W.; Jaspan, J. B.t; Maness, L. M. Leptin enters the brain by a saturable system independent of insulin. Peptides, 1996, 17, 305-311.
-
Banks, W. A.; Kastin, A. J.; Huang, W.; Jaspan, J. B.t; Maness, L. M. Leptin enters the brain by a saturable system independent of insulin. Peptides, 1996, 17, 305-311.
-
-
-
-
61
-
-
0033937071
-
Obesity is associated with a decreased leptin transport across the blood-brain barrier in rats
-
Burguera, B.; Couce, M. E.; Curran, G. L.; Jensen, M. D.; Lloyd, R. V.; Cleary, M. P.; Poduslo, J. F. Obesity is associated with a decreased leptin transport across the blood-brain barrier in rats. Diabetes, 2000, 49, 1219-1223.
-
(2000)
Diabetes
, vol.49
, pp. 1219-1223
-
-
Burguera, B.1
Couce, M.E.2
Curran, G.L.3
Jensen, M.D.4
Lloyd, R.V.5
Cleary, M.P.6
Poduslo, J.F.7
-
62
-
-
0030807358
-
Diet-induced obese mice develop peripheral, but not central, resistance to leptin
-
Van Heek, M.; Compton, D. S.; France, C. F.; Tedesco, R. P.; Fawzi, A. B.; Graziano, M. P. Sybertz, E. J.; Strader, C. D.; Davis, H. R., Jr. Diet-induced obese mice develop peripheral, but not central, resistance to leptin. J. Clin. Invest., 1997, 99, 385-390.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 385-390
-
-
Van Heek, M.1
Compton, D.S.2
France, C.F.3
Tedesco, R.P.4
Fawzi, A.B.5
Graziano, M.P.6
Sybertz, E.J.7
Strader, C.D.8
Davis Jr., H.R.9
-
63
-
-
0036088134
-
Effects of dietary fat types on body fatness, leptin, and ARC leptin receptor, NPY, and AgRP mRNA expression
-
Wang, H.; Storlien, L. H.; Huang, X. F. Effects of dietary fat types on body fatness, leptin, and ARC leptin receptor, NPY, and AgRP mRNA expression. Am. J. Physiol. Endocrinol. Metab., 2002, 282, E1352-1359.
-
(2002)
Am. J. Physiol. Endocrinol. Metab
, vol.282
-
-
Wang, H.1
Storlien, L.H.2
Huang, X.F.3
-
64
-
-
25144507707
-
Gene transfer technology: A preventive neurotherapy to curb obesity, ameliorate metabolic syndrome and extend life-expectancy
-
Kalra, S. P.; Kalra, P. S. Gene transfer technology: a preventive neurotherapy to curb obesity, ameliorate metabolic syndrome and extend life-expectancy. Trends Pharmacol. Sci., 2005, 26, 488-495.
-
(2005)
Trends Pharmacol. Sci
, vol.26
, pp. 488-495
-
-
Kalra, S.P.1
Kalra, P.S.2
-
65
-
-
33644847465
-
Subjugation of hypothalamic NPY and cohorts with central leptin gene therapy alleviates dyslipi-demia, insulin resistance, and obesity for life-time
-
Zukowska, Z. and Feuerstein, G, Eds, Birhauser Verlag Publishing House, Switzerland
-
Kalra, S. P.; Kalra, P. S. Subjugation of hypothalamic NPY and cohorts with central leptin gene therapy alleviates dyslipi-demia, insulin resistance, and obesity for life-time. In: Zukowska, Z. and Feuerstein, G. (Eds.), "NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders:Genes, Functions and Therapeutics." Birhauser Verlag Publishing House, Switzerland, 2006, pp. 157-169.
-
(2006)
NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders:Genes, Functions and Therapeutics
, pp. 157-169
-
-
Kalra, S.P.1
Kalra, P.S.2
-
66
-
-
0033305752
-
Leptin is released from the human brain: Influence of adiposity and gender
-
Wiesner, G.; Vaz, M.; Collier, G.; Seals, D.; Kaye, D.; Jennings, G.; Lambert, G.; Wilkinson, D.; Esler, M. Leptin is released from the human brain: influence of adiposity and gender. J. Clin. Endocrinol. Metab., 1999, 84, 2270-2274.
-
(1999)
J. Clin. Endocrinol. Metab
, vol.84
, pp. 2270-2274
-
-
Wiesner, G.1
Vaz, M.2
Collier, G.3
Seals, D.4
Kaye, D.5
Jennings, G.6
Lambert, G.7
Wilkinson, D.8
Esler, M.9
-
67
-
-
0033649274
-
The Brain is a source of leptin
-
Wilkinson, M.; Morash, B.; Ur, E. The Brain is a source of leptin. Front Horm. Res., 2000, 26, 106-125.
-
(2000)
Front Horm. Res
, vol.26
, pp. 106-125
-
-
Wilkinson, M.1
Morash, B.2
Ur, E.3
-
68
-
-
0031766974
-
Fate of leptin after intracerebroventricular injection into the mouse brain
-
Maness, L. M.; Kastin, A. J.; Farrell, C. L.; Banks, W. A. Fate of leptin after intracerebroventricular injection into the mouse brain. Endocrinology, 1998, 139, 4556-4562.
-
(1998)
Endocrinology
, vol.139
, pp. 4556-4562
-
-
Maness, L.M.1
Kastin, A.J.2
Farrell, C.L.3
Banks, W.A.4
-
69
-
-
15044363514
-
Adeno-associated virus and AAV vectors for gene delivery
-
Templeton-Smith, N, Ed, Marcel Dekker, New York, NY
-
Carter, B. J.; Burstein, H. Adeno-associated virus and AAV vectors for gene delivery. In: Templeton-Smith, N. [Ed.], Theruapeutics Mechanisms and Strategies. Marcel Dekker, New York, NY, 2004, pp. 71-1011.
-
(2004)
Theruapeutics Mechanisms and Strategies
, pp. 71-1011
-
-
Carter, B.J.1
Burstein, H.2
-
70
-
-
0029908857
-
Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy
-
Chen, G.; Koyama, K.; Yuan, X.; Lee, Y.; Zhou, Y. T.; O'Doherty, R.; Newgard, C. B.; Unger, R. H. Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy. Proc. Natl. Acad. Sci. USA, 1996, 93, 14795-14799.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14795-14799
-
-
Chen, G.1
Koyama, K.2
Yuan, X.3
Lee, Y.4
Zhou, Y.T.5
O'Doherty, R.6
Newgard, C.B.7
Unger, R.H.8
-
71
-
-
3142767549
-
Leptin Receptor Gene Transfer into the Arcuate Nucleus of Female Fatty Zucker Rats Using Recombinant Adeno-Associated Viral Vectors Stimulates the Hypothalamo-Pituitary-Gonadal Axis
-
Keen-Rhinebart, E.; Kalra, S. P.; Kalra, P. S. Leptin Receptor Gene Transfer into the Arcuate Nucleus of Female Fatty Zucker Rats Using Recombinant Adeno-Associated Viral Vectors Stimulates the Hypothalamo-Pituitary-Gonadal Axis. Biol. Reprod., 2004, 71, 266-272.
-
(2004)
Biol. Reprod
, vol.71
, pp. 266-272
-
-
Keen-Rhinebart, E.1
Kalra, S.P.2
Kalra, P.S.3
-
72
-
-
25144497089
-
AAV mediated leptin receptor installation improves energy balance and the reproductive status of obese female Koletsky rats
-
Keen-Rhinehart, E.; Kalra, S. P.; Kalra, P. S. AAV mediated leptin receptor installation improves energy balance and the reproductive status of obese female Koletsky rats. Peptides, 2005, 26, 2567-2578.
-
(2005)
Peptides
, vol.26
, pp. 2567-2578
-
-
Keen-Rhinehart, E.1
Kalra, S.P.2
Kalra, P.S.3
-
74
-
-
0034714042
-
Long-term differential modulation of genes encoding orexigenic and anorexigenic peptides by leptin delivered by rAAV vector in ob/ob mice. Relationship with body weight change
-
Dhillon, H.; Ge, Y.; Minter, R. M.; Prima, V.; Moldawer, L. L.; Muzyczka, N.; Zolotukhin, S.; Kalra, P. S.; Kalra, S. P. Long-term differential modulation of genes encoding orexigenic and anorexigenic peptides by leptin delivered by rAAV vector in ob/ob mice. Relationship with body weight change. Regul. Pept., 2000, 92, 97-105.
-
(2000)
Regul. Pept
, vol.92
, pp. 97-105
-
-
Dhillon, H.1
Ge, Y.2
Minter, R.M.3
Prima, V.4
Moldawer, L.L.5
Muzyczka, N.6
Zolotukhin, S.7
Kalra, P.S.8
Kalra, S.P.9
-
75
-
-
0034882656
-
Dose-Dependent Effects of Central Leptin Gene Therapy on Genes That Regulate Body Weight and Appetite in the Hypothalamus
-
Dhillon, H.; Kalra, S. P.; Kalra, P. S. Dose-Dependent Effects of Central Leptin Gene Therapy on Genes That Regulate Body Weight and Appetite in the Hypothalamus. Mol. Ther., 2001, 4, 139-145.
-
(2001)
Mol. Ther
, vol.4
, pp. 139-145
-
-
Dhillon, H.1
Kalra, S.P.2
Kalra, P.S.3
-
76
-
-
0035876708
-
Central Leptin Gene, Therapy Suppresses Body Weight Gain, Adiposity and Serum Insulin Without Affecting Food Consumption in Normal Rats: A Long-Term Study
-
bhillon, H.; Kalra, S. P.; Prima, V. Zolotukhin, S.; Scarpace, P. J.; Moldawer, L. L.; Muzyczka, N.; Kalra, P. S. Central Leptin Gene, Therapy Suppresses Body Weight Gain, Adiposity and Serum Insulin Without Affecting Food Consumption in Normal Rats: A Long-Term Study. Regul. Pept., 2001, 99, 69-77.
-
(2001)
Regul. Pept
, vol.99
, pp. 69-77
-
-
bhillon, H.1
Kalra, S.P.2
Prima, V.3
Zolotukhin, S.4
Scarpace, P.J.5
Moldawer, L.L.6
Muzyczka, N.7
Kalra, P.S.8
-
77
-
-
22544464405
-
Suppression of fat deposition for the life time of rodents with gene therapy
-
Boghossian, S.; Lecklin, A. H.; Torto, R.; Kalra, P. S.; Kalra, S. P. Suppression of fat deposition for the life time of rodents with gene therapy. Peptides, 2005, 26, 1512-1519.
-
(2005)
Peptides
, vol.26
, pp. 1512-1519
-
-
Boghossian, S.1
Lecklin, A.H.2
Torto, R.3
Kalra, P.S.4
Kalra, S.P.5
-
78
-
-
0036827697
-
Evidence for the existence of distinct central appetite and energy expenditure pathways and stimulation of ghrelin as revealed by hypothalamic site-specific leptin gene therapy
-
Bagnasco, M.; Dube, M. G.; Kalra, P. S.; Kalra, S. P. Evidence for the existence of distinct central appetite and energy expenditure pathways and stimulation of ghrelin as revealed by hypothalamic site-specific leptin gene therapy. Endocrinology, 2002, 143, 4409-4421.
-
(2002)
Endocrinology
, vol.143
, pp. 4409-4421
-
-
Bagnasco, M.1
Dube, M.G.2
Kalra, P.S.3
Kalra, S.P.4
-
79
-
-
2142687620
-
Leptin expression in hypothalamic PVN reverses dietary obesity and hyperinsulinemia but stimulates ghrelin
-
Bagnasco, M.; Dube, M. G. Katz, A.; Kalra, P. S.; Kalra, S. P. Leptin expression in hypothalamic PVN reverses dietary obesity and hyperinsulinemia but stimulates ghrelin. Obesity Res., 2003, 11, 1463-1470.
-
(2003)
Obesity Res
, vol.11
, pp. 1463-1470
-
-
Bagnasco, M.1
Dube, M.G.2
Katz, A.3
Kalra, P.S.4
Kalra, S.P.5
-
80
-
-
0036078658
-
Central LIF gene therapy suppresses food intake, body weight, serum leptin and insulin for extended periods
-
Beretta, E.; Dube, M. G.; Kalra, P. S.; Kalra, S. P. Central LIF gene therapy suppresses food intake, body weight, serum leptin and insulin for extended periods. Peptides, 2002, 23, 875-984.
-
(2002)
Peptides
, vol.23
, pp. 875-984
-
-
Beretta, E.1
Dube, M.G.2
Kalra, P.S.3
Kalra, S.P.4
-
81
-
-
85047681825
-
Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: Effects on senim ghrelin and appetite-regulating genes
-
Beretta, E.; Dube, M. G.; Kalra, P. S.; Kalra, S. P. Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: Effects on senim ghrelin and appetite-regulating genes. Ped. Res., 2002, 52, 189-198.
-
(2002)
Ped. Res
, vol.52
, pp. 189-198
-
-
Beretta, E.1
Dube, M.G.2
Kalra, P.S.3
Kalra, S.P.4
-
82
-
-
20444421276
-
Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation
-
Lecklin, A. H.; Dube, M. G.; Torto, R.; Kalra, P. S.; Kalra, S. P. Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation. Peptides, 2005, 26, 1176-1187.
-
(2005)
Peptides
, vol.26
, pp. 1176-1187
-
-
Lecklin, A.H.1
Dube, M.G.2
Torto, R.3
Kalra, P.S.4
Kalra, S.P.5
-
83
-
-
33846565392
-
Increased Leptin Expression in the Dorsal Vagal Complex Suppresses Adiposity without Affecting Energy Intake and Metabolic Hormones
-
Boghossian, S.; Lecklin, A.; Dube, M. G.; Kalra, P. S.; Kalra, S. P. Increased Leptin Expression in the Dorsal Vagal Complex Suppresses Adiposity without Affecting Energy Intake and Metabolic Hormones. Obesity, 2006, 14, 1003-1009.
-
(2006)
Obesity
, vol.14
, pp. 1003-1009
-
-
Boghossian, S.1
Lecklin, A.2
Dube, M.G.3
Kalra, P.S.4
Kalra, S.P.5
-
84
-
-
33846565483
-
To subjugate NPY is to improve the quality of life and live longer. Peptides. Special NPY Issue
-
in Press
-
Kalra, S. P.; Kalra, P. S. To subjugate NPY is to improve the quality of life and live longer. Peptides. Special NPY Issue, 2007, (in Press).
-
(2007)
-
-
Kalra, S.P.1
Kalra, P.S.2
-
85
-
-
0032996822
-
Cross-sectional and longitudinal analysis of age-associated changes in body composition of male Brown Norway rats: Association of serum leptin levels with peripheral adiposity
-
Wolden-Hanson, T.; Marck, B. T.; Smith, L.; Matsumoto,A. M. Cross-sectional and longitudinal analysis of age-associated changes in body composition of male Brown Norway rats: association of serum leptin levels with peripheral adiposity. J. Gerontol. A Biol. Sci. Med. Sci., 1999, 54, B99-B107.
-
(1999)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.54
-
-
Wolden-Hanson, T.1
Marck, B.T.2
Smith, L.3
Matsumoto, A.M.4
-
86
-
-
0020059410
-
Life span study of SPF Fischer 344 male rats fed ad libitum or restricted diets: Longevity, growth, lean body mass and disease
-
Yu, B. P.; Masoro, E. J.; Murata, I.; Bertrand, H. A.; Lynd, F. T. Life span study of SPF Fischer 344 male rats fed ad libitum or restricted diets: longevity, growth, lean body mass and disease. J. Gerontol., 1982, 37, 130-141.
-
(1982)
J. Gerontol
, vol.37
, pp. 130-141
-
-
Yu, B.P.1
Masoro, E.J.2
Murata, I.3
Bertrand, H.A.4
Lynd, F.T.5
-
87
-
-
33750577043
-
Central teptin therapy blocks ovariectomy-induced adiposity
-
Torto, R.; Dube, M. G.; Kalra, P. S.; Kalra, S. P. Central teptin therapy blocks ovariectomy-induced adiposity. Obesity, 2006, 14, 1312-1319.
-
(2006)
Obesity
, vol.14
, pp. 1312-1319
-
-
Torto, R.1
Dube, M.G.2
Kalra, P.S.3
Kalra, S.P.4
-
88
-
-
27944502118
-
Central Leptin Differentially Modulates Ultradian Secretory Patterns of Insulin, Leptin and Ghrelin Independent of Effects on Food Intake and Body Weight
-
Otukonyong, E. E.; Dube, M. G.; Torto, R.; Kalra, P. S.; Kalra, S. P. Central Leptin Differentially Modulates Ultradian Secretory Patterns of Insulin, Leptin and Ghrelin Independent of Effects on Food Intake and Body Weight. Peptides, 2005, 26, 2559-2566.
-
(2005)
Peptides
, vol.26
, pp. 2559-2566
-
-
Otukonyong, E.E.1
Dube, M.G.2
Torto, R.3
Kalra, P.S.4
Kalra, S.P.5
-
89
-
-
25144497560
-
High fat diet-induced ultradian leptin and insulin hypersecretion and ghrelin is absent in obesity-resistant rats
-
Otukonyong, E. E.; Dube, M. G.; Torto, R.; Kalra, P. S.; Kalra, S. P. High fat diet-induced ultradian leptin and insulin hypersecretion and ghrelin is absent in obesity-resistant rats. Obes. Res., 2005, 113, 991-999.
-
(2005)
Obes. Res
, vol.113
, pp. 991-999
-
-
Otukonyong, E.E.1
Dube, M.G.2
Torto, R.3
Kalra, P.S.4
Kalra, S.P.5
-
90
-
-
33750948987
-
Hypothalamic clamp on insulin release by leptin-transgene expression
-
Boghossian, S.; Dube, M. G.; Torto, R.; Kalra, P. S.; Kalra, S. P. Hypothalamic clamp on insulin release by leptin-transgene expression. Peptides, 2006, 27, 3245-3254.
-
(2006)
Peptides
, vol.27
, pp. 3245-3254
-
-
Boghossian, S.1
Dube, M.G.2
Torto, R.3
Kalra, P.S.4
Kalra, S.P.5
-
91
-
-
0035911803
-
-
Buijs, R. M.; Chun, S. J.; Niijima, ~k.; Romijn, H. Li Nagai, K. Parasympathetic and sympathetic control of the pancreas: a role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of fodd intake. J. Comp. Neurol., 2001,431, 405-423.
-
Buijs, R. M.; Chun, S. J.; Niijima, ~k.; Romijn, H. Li Nagai, K. Parasympathetic and sympathetic control of the pancreas: a role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of fodd intake. J. Comp. Neurol., 2001,431, 405-423.
-
-
-
-
92
-
-
0033621087
-
Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia
-
Wang, Z. W.; Zhou, Y. T.; Kakurna, T.; Lee, Y.; Higa, M.; Kalra, S. P.; Dube, M. G.; Kalra, P. S.; Unger, R. H. Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia. Proc. Natl. Acad. Sci. USA, 1999, 96, 10373-10378.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10373-10378
-
-
Wang, Z.W.1
Zhou, Y.T.2
Kakurna, T.3
Lee, Y.4
Higa, M.5
Kalra, S.P.6
Dube, M.G.7
Kalra, P.S.8
Unger, R.H.9
-
93
-
-
0035161705
-
Neuroanatomical specificity of the circuits controlling sympathetic outflow to different targets
-
Sved, A. F.; Cano, G.; Card, J. P. Neuroanatomical specificity of the circuits controlling sympathetic outflow to different targets. Clin. Exp. Pharmacol. Physiol., 2001, 28, 115-119.
-
(2001)
Clin. Exp. Pharmacol. Physiol
, vol.28
, pp. 115-119
-
-
Sved, A.F.1
Cano, G.2
Card, J.P.3
-
94
-
-
4444256688
-
NPY and Y receptors: Lessons from transgenic and knockout models
-
Lin, S.; Boey, D.; Herzog, H. NPY and Y receptors: lessons from transgenic and knockout models. Neuropeptides, 2004, 38, 189-200.
-
(2004)
Neuropeptides
, vol.38
, pp. 189-200
-
-
Lin, S.1
Boey, D.2
Herzog, H.3
-
95
-
-
33751243625
-
Combined deletion of Y1, Y2, and Y4 receptors prevents hypothalamic neuropeptide Y overexpression-induced hyperinsulinemia despite persistence of hyperohagia and obesity
-
Lin, E. J.; Samsbury, A.; Lee, N. J.; Boey, D.; Couzens, M.; Enriquez, R.; Slack, K.; Bland, R.; During, M. J.; Herzog, H. Combined deletion of Y1, Y2, and Y4 receptors prevents hypothalamic neuropeptide Y overexpression-induced hyperinsulinemia despite persistence of hyperohagia and obesity. Endocrinology, 2006, 147, 5094-5101.
-
(2006)
Endocrinology
, vol.147
, pp. 5094-5101
-
-
Lin, E.J.1
Samsbury, A.2
Lee, N.J.3
Boey, D.4
Couzens, M.5
Enriquez, R.6
Slack, K.7
Bland, R.8
During, M.J.9
Herzog, H.10
-
96
-
-
0032918044
-
A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse
-
Wang, J.; Takeuchi, T.; Tanaka, S.; Kubo, S. K.; Kayo, T.; Lu, D.; Takata, K.; Koizumi, A.; Izumi, T. A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse. J. Clin. Invest., 1999, 103, 27-37.
-
(1999)
J. Clin. Invest
, vol.103
, pp. 27-37
-
-
Wang, J.1
Takeuchi, T.2
Tanaka, S.3
Kubo, S.K.4
Kayo, T.5
Lu, D.6
Takata, K.7
Koizumi, A.8
Izumi, T.9
-
97
-
-
0030907296
-
A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 [Akita] mutant mice
-
Yoshioka, M.; Kayo, T.; Ikeda, T. and Koizumi, A. A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 [Akita] mutant mice. Diabetes, 1997, 46, 887-894.
-
(1997)
Diabetes
, vol.46
, pp. 887-894
-
-
Yoshioka, M.1
Kayo, T.2
Ikeda, T.3
Koizumi, A.4
-
98
-
-
0033037727
-
Leptin restores euglycemia and normalizes glucose turnover in insulin- deficient diabetes in the rat
-
Chinookoswong, N.; Wang, J. L.; Shi, Z. Q. Leptin restores euglycemia and normalizes glucose turnover in insulin- deficient diabetes in the rat. Diabetes, 1999, 48, 1487-1492.
-
(1999)
Diabetes
, vol.48
, pp. 1487-1492
-
-
Chinookoswong, N.1
Wang, J.L.2
Shi, Z.Q.3
-
99
-
-
0027519963
-
Mandatory neuropeptide-steroid signaling for the preovulatory luteinizing hormone-releasing hormone discharge
-
Kalra, S. P. Mandatory neuropeptide-steroid signaling for the preovulatory luteinizing hormone-releasing hormone discharge. Endocr. Rev., 1993, 14, 507-538.
-
(1993)
Endocr. Rev
, vol.14
, pp. 507-538
-
-
Kalra, S.P.1
-
100
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
Chehab, F. F; Lim, M. E.; Lu, R. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat. Genet., 1996, 12, 318-320.
-
(1996)
Nat. Genet
, vol.12
, pp. 318-320
-
-
Chehab, F.F.1
Lim, M.E.2
Lu, R.3
-
101
-
-
34547770365
-
-
Boghossian, S.; Ueno, N.; Dube, M. G.; Kalra, P. S.; Kalra, S. P. Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin. Neurobiol Aging. 2007, doi:10.1016/j,neurobiolaging. 2006.08.010.
-
Boghossian, S.; Ueno, N.; Dube, M. G.; Kalra, P. S.; Kalra, S. P. Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin. Neurobiol Aging. 2007, doi:10.1016/j,neurobiolaging. 2006.08.010.
-
-
-
-
102
-
-
2342518168
-
The complex effects of leptin-on bone metabolism through multiple pathways
-
Thomas, T. The complex effects of leptin-on bone metabolism through multiple pathways. Curr. Opin. Pharmacol., 2004, 4, 295-300.
-
(2004)
Curr. Opin. Pharmacol
, vol.4
, pp. 295-300
-
-
Thomas, T.1
-
103
-
-
0036212496
-
Hypothalamic Y2 receptors regulate bone formation
-
Baldock, P. A.; Sainsbury, A.; Couzens, M.; Enriquez, R. F.; Thomas, G. P.; Gardiner, E. M.; Herzog, H. Hypothalamic Y2 receptors regulate bone formation. J. Clin. Invest., 2002, 109, 915-921.
-
(2002)
J. Clin. Invest
, vol.109
, pp. 915-921
-
-
Baldock, P.A.1
Sainsbury, A.2
Couzens, M.3
Enriquez, R.F.4
Thomas, G.P.5
Gardiner, E.M.6
Herzog, H.7
-
104
-
-
34247546688
-
Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice
-
Iwaniec, U. T.; Boghossian, S.; Lapke, P.-D.; Turner, R. T.; Kalra, S. P. Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice. Peptides, 2007, 28, 1012-1019.
-
(2007)
Peptides
, vol.28
, pp. 1012-1019
-
-
Iwaniec, U.T.1
Boghossian, S.2
Lapke, P.-D.3
Turner, R.T.4
Kalra, S.P.5
-
105
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
Tatar, M., Bartke, A.; Antebi, A. The endocrine regulation of aging by insulin-like signals. Science, 2003, 299, 1346-1351.
-
(2003)
Science
, vol.299
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
|