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Volumn 4, Issue 3, 2004, Pages 295-300

The complex effects of leptin on bone metabolism through multiple pathways

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; LEPTIN; NEUROPEPTIDE Y; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; VITAMIN D;

EID: 2342518168     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2004.01.009     Document Type: Review
Times cited : (116)

References (62)
  • 1
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spiegelman B.M. Flier J.S. Obesity and the regulation of energy balance Cell 104 2001 531-543
    • (2001) Cell , vol.104 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 2
    • 0032941038 scopus 로고    scopus 로고
    • Central administration of leptin to ovariectomized ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: Evidence for a dissociation of effects on appetite and neuroendocrine function
    • Henry B.A. Goding J.W. Alexander W.S. Tilbrook A.J. Canny B.J. Dunshea F. Rao A. Mansell A. Clarke I.J. Central administration of leptin to ovariectomized ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: evidence for a dissociation of effects on appetite and neuroendocrine function Endocrinology 140 1999 1175-1182
    • (1999) Endocrinology , vol.140 , pp. 1175-1182
    • Henry, B.A.1    Goding, J.W.2    Alexander, W.S.3    Tilbrook, A.J.4    Canny, B.J.5    Dunshea, F.6    Rao, A.7    Mansell, A.8    Clarke, I.J.9
  • 3
    • 0003145938 scopus 로고
    • Lineage of osteogenic cells and their relationship to the stromal system
    • Edited by Peck WA. Amsterdam: Elsevier
    • Owen M: Lineage of osteogenic cells and their relationship to the stromal system. In Bone and Mineral Research Vol 3. Edited by Peck WA. Amsterdam: Elsevier; 1985:1-23.
    • (1985) Bone and Mineral Research , vol.3 , pp. 1-23
    • Owen, M.1
  • 4
    • 0032982438 scopus 로고    scopus 로고
    • Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes
    • Thomas T. Gori F. Khosla S. Jensen M.D. Burguera B. Riggs B.L. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes Endocrinology 140 1999 1630-1638
    • (1999) Endocrinology , vol.140 , pp. 1630-1638
    • Thomas, T.1    Gori, F.2    Khosla, S.3    Jensen, M.D.4    Burguera, B.5    Riggs, B.L.6
  • 7
    • 0037174115 scopus 로고    scopus 로고
    • Leptin receptor isoform expression in rat osteoblasts and their functional analysis
    • Lee Y.J. Park J.H. Ju S.K. You K.H. Ko J.S. Kim H.M. Leptin receptor isoform expression in rat osteoblasts and their functional analysis FEBS Lett 528 2002 43-47
    • (2002) FEBS Lett. , vol.528 , pp. 43-47
    • Lee, Y.J.1    Park, J.H.2    Ju, S.K.3    You, K.H.4    Ko, J.S.5    Kim, H.M.6
  • 10
    • 15844410399 scopus 로고    scopus 로고
    • Obese gene expression alters the ability of 30A5 preadipocytes to respond to lipogenic hormones
    • Bai Y. Zhang S. Kim K.S. Lee J.K. Kim K.H. Obese gene expression alters the ability of 30A5 preadipocytes to respond to lipogenic hormones J Biol Chem 271 1996 13939-13942
    • (1996) J. Biol. Chem. , vol.271 , pp. 13939-13942
    • Bai, Y.1    Zhang, S.2    Kim, K.S.3    Lee, J.K.4    Kim, K.H.5
  • 11
    • 0035958030 scopus 로고    scopus 로고
    • Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells
    • Lai C.F. Chaudhary L. Fausto A. Halstead L.R. Ory D.S. Avioli L.V. Cheng S.L. Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells J Biol Chem 276 2001 14443-14450
    • (2001) J. Biol. Chem. , vol.276 , pp. 14443-14450
    • Lai, C.F.1    Chaudhary, L.2    Fausto, A.3    Halstead, L.R.4    Ory, D.S.5    Avioli, L.V.6    Cheng, S.L.7
  • 12
    • 0038776380 scopus 로고    scopus 로고
    • Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma
    • Hu E. Kim J.B. Sarraf P. Spiegelman B.M. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma Science 274 1996 2100-2103
    • (1996) Science , vol.274 , pp. 2100-2103
    • Hu, E.1    Kim, J.B.2    Sarraf, P.3    Spiegelman, B.M.4
  • 13
    • 0036234187 scopus 로고    scopus 로고
    • Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling
    • Gordeladze J.O. Drevon C.A. Syversen U. Reseland J.E. Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: impact on differentiation markers, apoptosis, and osteoclastic signaling J Cell Biochem 85 2002 825-836
    • (2002) J. Cell Biochem. , vol.85 , pp. 825-836
    • Gordeladze, J.O.1    Drevon, C.A.2    Syversen, U.3    Reseland, J.E.4
  • 19
    • 25544435520 scopus 로고    scopus 로고
    • Leptin modulates both resorption and formation while preventing disuse-induced bone loss in tail-suspended female rats
    • Thomas T. Martin A. de Vittoris R. Lafage-Proust M.H. Alexandre C. Vico L. Leptin modulates both resorption and formation while preventing disuse-induced bone loss in tail-suspended female rats J Bone Miner Res 18 Suppl2 2003 S42
    • (2003) J. Bone Miner. Res. , vol.18 , Issue.SUPPL. 2
    • Thomas, T.1    Martin, A.2    de Vittoris, R.3    Lafage-Proust, M.H.4    Alexandre, C.5    Vico, L.6
  • 21
    • 0034896519 scopus 로고    scopus 로고
    • Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women
    • Thomas T. Burguera B. Melton L.J. III Atkinson E.J. Riggs B.L. Khosla S. Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women Bone 29 2001 114-120
    • (2001) Bone , vol.29 , pp. 114-120
    • Thomas, T.1    Burguera, B.2    Melton III, L.J.3    Atkinson, E.J.4    Riggs, B.L.5    Khosla, S.6
  • 22
    • 0031773271 scopus 로고    scopus 로고
    • Plasma leptin values in relation to bone mass and density and to dynamic biochemical markers of bone resorption and formation in post-menopausal women
    • Goulding A. Taylor R.W. Plasma leptin values in relation to bone mass and density and to dynamic biochemical markers of bone resorption and formation in post-menopausal women Calcif Tissue Int 63 1998 456-458
    • (1998) Calcif. Tissue Int. , vol.63 , pp. 456-458
    • Goulding, A.1    Taylor, R.W.2
  • 24
    • 0036785268 scopus 로고    scopus 로고
    • Relationship of serum leptin concentration with bone mineral density in the United States population
    • Ruhl C.E. Everhart J.E. Relationship of serum leptin concentration with bone mineral density in the United States population J Bone Miner Res 17 2002 1896-1903
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 1896-1903
    • Ruhl, C.E.1    Everhart, J.E.2
  • 30
    • 0035155707 scopus 로고    scopus 로고
    • Influence of insulin-like growth factor-1 and leptin on bone mass in healthy postmenopausal women
    • Martini G. Valenti R. Giovani S. Franci B. Campagna S. Nuti R. Influence of insulin-like growth factor-1 and leptin on bone mass in healthy postmenopausal women Bone 28 2001 113-117
    • (2001) Bone , vol.28 , pp. 113-117
    • Martini, G.1    Valenti, R.2    Giovani, S.3    Franci, B.4    Campagna, S.5    Nuti, R.6
  • 31
    • 0037298896 scopus 로고    scopus 로고
    • Inverse correlation between serum leptin concentration and vertebral bone density in postmenopausal women
    • Ushiroyama T. Ikeda A. Hosotani T. Higashiyama T. Ueki M. Inverse correlation between serum leptin concentration and vertebral bone density in postmenopausal women Gynecol Endocrinol 17 2003 31-36
    • (2003) Gynecol. Endocrinol. , vol.17 , pp. 31-36
    • Ushiroyama, T.1    Ikeda, A.2    Hosotani, T.3    Higashiyama, T.4    Ueki, M.5
  • 33
    • 0033784091 scopus 로고    scopus 로고
    • Relationship of serum leptin levels with body composition, sex steroid, and insulin levels in men and women
    • Thomas T. Burguera B. Melton L.J. III Atkinson E.J. Riggs B.L. Khosla S. Relationship of serum leptin levels with body composition, sex steroid, and insulin levels in men and women Metabolism 49 2000 1278-1284
    • (2000) Metabolism , vol.49 , pp. 1278-1284
    • Thomas, T.1    Burguera, B.2    Melton III, L.J.3    Atkinson, E.J.4    Riggs, B.L.5    Khosla, S.6
  • 34
    • 0242708800 scopus 로고    scopus 로고
    • Serum leptin as a determinant of bone resorption in healthy postmenopausal women
    • Roux C. Arabi A. Porcher R. Garnero P. Serum leptin as a determinant of bone resorption in healthy postmenopausal women Bone 33 2003 847-852
    • (2003) Bone , vol.33 , pp. 847-852
    • Roux, C.1    Arabi, A.2    Porcher, R.3    Garnero, P.4
  • 35
    • 0036846461 scopus 로고    scopus 로고
    • Effect of subcutaneous leptin replacement therapy on bone metabolism in patients with generalized lipodystrophy
    • Simha V. Zerwekh J.E. Sakhaee K. Garg A. Effect of subcutaneous leptin replacement therapy on bone metabolism in patients with generalized lipodystrophy J Clin Endocrinol Metab 87 2002 4942-4945
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 4942-4945
    • Simha, V.1    Zerwekh, J.E.2    Sakhaee, K.3    Garg, A.4
  • 36
    • 0141673531 scopus 로고    scopus 로고
    • Leptin modulates inflammatory cytokine and neuroendocrine responses to endotoxin in the primate
    • Xiao E. Xia-Zhang L. Vulliemoz N.R. Ferin M. Wardlaw S.L. Leptin modulates inflammatory cytokine and neuroendocrine responses to endotoxin in the primate Endocrinology 144 2003 4350-4353
    • (2003) Endocrinology , vol.144 , pp. 4350-4353
    • Xiao, E.1    Xia-Zhang, L.2    Vulliemoz, N.R.3    Ferin, M.4    Wardlaw, S.L.5
  • 37
    • 0036800760 scopus 로고    scopus 로고
    • Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
    • Farooqi I.S. Matarese G. Lord G.M. Keogh J.M. Lawrence E. Agwu C. Sanna V. Jebb S.A. Perna F. Fontana S. et al. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency J Clin Invest 110 2002 1093-1103
    • (2002) J. Clin. Invest. , vol.110 , pp. 1093-1103
    • Farooqi, I.S.1    Matarese, G.2    Lord, G.M.3    Keogh, J.M.4    Lawrence, E.5    Agwu, C.6    Sanna, V.7    Jebb, S.A.8    Perna, F.9    Fontana, S.10
  • 41
    • 0035999436 scopus 로고    scopus 로고
    • Leptin acts as a growth factor on the chondrocytes of skeletal growth centers
    • Maor G. Rochwerger M. Segev Y. Phillip M. Leptin acts as a growth factor on the chondrocytes of skeletal growth centers J Bone Miner Res 17 2002 1034-1043
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 1034-1043
    • Maor, G.1    Rochwerger, M.2    Segev, Y.3    Phillip, M.4
  • 42
    • 0042242698 scopus 로고    scopus 로고
    • Effects of leptin to cultured growth plate chondrocytes
    • Nakajima R. Inada H. Koike T. Yamano T. Effects of leptin to cultured growth plate chondrocytes Horm Res 60 2003 91-98
    • (2003) Horm. Res. , vol.60 , pp. 91-98
    • Nakajima, R.1    Inada, H.2    Koike, T.3    Yamano, T.4
  • 43
    • 0345688661 scopus 로고    scopus 로고
    • Leptin induces growth hormone secretion from peripheral blood mononuclear cells via a protein kinase C- and nitric oxide-dependent mechanism
    • Dixit V.D. Mielenz M. Taub D.D. Parvizi N. Leptin induces growth hormone secretion from peripheral blood mononuclear cells via a protein kinase C- and nitric oxide-dependent mechanism Endocrinology 144 2003 5595-5603
    • (2003) Endocrinology , vol.144 , pp. 5595-5603
    • Dixit, V.D.1    Mielenz, M.2    Taub, D.D.3    Parvizi, N.4
  • 44
  • 52
    • 0026591555 scopus 로고
    • Bone structure and calcium metabolism in obese Zucker rats
    • Foldes J. Shih M.S. Levy J. Bone structure and calcium metabolism in obese Zucker rats Int J Obes 16 1992 95-102
    • (1992) Int. J. Obes. , vol.16 , pp. 95-102
    • Foldes, J.1    Shih, M.S.2    Levy, J.3
  • 54
    • 0041476040 scopus 로고    scopus 로고
    • Characterization of bone structure in leptin receptor-deficient Zucker (fa/fa) rats
    • Tamasi J.A. Arey B.J. Bertolini D.R. Feyen J.H.M. Characterization of bone structure in leptin receptor-deficient Zucker (fa/fa) rats J Bone Miner Res 18 2003 1605-1611
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 1605-1611
    • Tamasi, J.A.1    Arey, B.J.2    Bertolini, D.R.3    Feyen, J.H.M.4
  • 56
    • 0042922594 scopus 로고    scopus 로고
    • Monosodium glutamate-sensitive hypothalamic neurons contribute to the control of bone mass
    • Elefteriou F. Takeda S. Liu X. Armstrong D. Karsenty G. Monosodium glutamate-sensitive hypothalamic neurons contribute to the control of bone mass Endocrinology 144 2003 3842-3847
    • (2003) Endocrinology , vol.144 , pp. 3842-3847
    • Elefteriou, F.1    Takeda, S.2    Liu, X.3    Armstrong, D.4    Karsenty, G.5
  • 59
    • 1542331341 scopus 로고    scopus 로고
    • Beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong Osteoporosis Study
    • Pasco J.A. Henry M.J. Sanders K.M. Kotowicz M.A. Seeman E. Nicholson G.C. Beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong Osteoporosis Study J Bone Miner Res 19 2004 19-24
    • (2004) J. Bone Miner. Res. , vol.19 , pp. 19-24
    • Pasco, J.A.1    Henry, M.J.2    Sanders, K.M.3    Kotowicz, M.A.4    Seeman, E.5    Nicholson, G.C.6
  • 61
    • 1442274634 scopus 로고    scopus 로고
    • Leptin corrects increased gene expression of renal 25-hydroxyvitamin D3-1 alpha-hydroxylase and -24-hydroxylase in leptin-deficient, ob/ob mice
    • Matsunuma A. Kawane T. Maeda T. Hamada S. Horiuchi N. Leptin corrects increased gene expression of renal 25-hydroxyvitamin D3-1 alpha-hydroxylase and -24-hydroxylase in leptin-deficient, ob/ob mice Endocrinology 145 2004 1367-1375
    • (2004) Endocrinology , vol.145 , pp. 1367-1375
    • Matsunuma, A.1    Kawane, T.2    Maeda, T.3    Hamada, S.4    Horiuchi, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.