-
1
-
-
0028238769
-
Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
-
Snider WD (1994) Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77:627-638
-
(1994)
Cell
, vol.77
, pp. 627-638
-
-
Snider, W.D.1
-
2
-
-
0028916394
-
Functional interactions of neurotrophins and neurotrophin receptors
-
Bothwell M (1995) Functional interactions of neurotrophins and neurotrophin receptors. Annu Rev Neurosci 18:223-253
-
(1995)
Annu Rev Neurosci
, vol.18
, pp. 223-253
-
-
Bothwell, M.1
-
3
-
-
0029925683
-
Intracellular signaling pathways activated by neurotrophic factors
-
Segal RA, Greenberg ME (1996) Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci 19:463-489
-
(1996)
Annu Rev Neurosci
, vol.19
, pp. 463-489
-
-
Segal, R.A.1
Greenberg, M.E.2
-
5
-
-
0029061444
-
NGF-stimulated retrograde transport of trkA in the mammalian nervous system
-
Ehlers MD, Kaplan DR, Price DL, Koliatsos VE (1995) NGF-stimulated retrograde transport of trkA in the mammalian nervous system. J Cell Biol 130:149-156
-
(1995)
J Cell Biol
, vol.130
, pp. 149-156
-
-
Ehlers, M.D.1
Kaplan, D.R.2
Price, D.L.3
Koliatsos, V.E.4
-
6
-
-
10544248585
-
Endocytosis of activated TrkA: Evidence that nerve growth factor induces formation of signaling endosomes
-
Grimes ML, Zhou J, Beattie EC, Yuen EC, Hall DE, Valletta JS, Topp KS, LaVail JH, Bunnett NW, Mobley WC (1996) Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes. J Neurosci 16:7950-7964
-
(1996)
J Neurosci
, vol.16
, pp. 7950-7964
-
-
Grimes, M.L.1
Zhou, J.2
Beattie, E.C.3
Yuen, E.C.4
Hall, D.E.5
Valletta, J.S.6
Topp, K.S.7
LaVail, J.H.8
Bunnett, N.W.9
Mobley, W.C.10
-
7
-
-
2542421751
-
Dynein motors transport activated Trks to promote survival of target-dependent neurons
-
Heerssen HM, Pazyra MF, Segal RA (2004) Dynein motors transport activated Trks to promote survival of target-dependent neurons. Nat Neurosci 7:596-604
-
(2004)
Nat Neurosci
, vol.7
, pp. 596-604
-
-
Heerssen, H.M.1
Pazyra, M.F.2
Segal, R.A.3
-
8
-
-
0842333853
-
Signaling endosome hypothesis: A cellular mechanism for long distance communication
-
Howe CL, Mobley WC (2004) Signaling endosome hypothesis: a cellular mechanism for long distance communication. J Neurobiol 58:207-216
-
(2004)
J Neurobiol
, vol.58
, pp. 207-216
-
-
Howe, C.L.1
Mobley, W.C.2
-
9
-
-
23044515099
-
Functions and mechanisms of retrograde neurotrophin signalling
-
Zweifel LS, Kuruvilla R, Ginty DD (2005) Functions and mechanisms of retrograde neurotrophin signalling. Nat Rev Neurosci 6:615-625
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 615-625
-
-
Zweifel, L.S.1
Kuruvilla, R.2
Ginty, D.D.3
-
10
-
-
0036498257
-
Location, location, location: A spatial view of neurotrophin signal transduction
-
Heerssen HM, Segal RA (2002) Location, location, location: a spatial view of neurotrophin signal transduction. Trends Neurosci 25:160-165
-
(2002)
Trends Neurosci
, vol.25
, pp. 160-165
-
-
Heerssen, H.M.1
Segal, R.A.2
-
11
-
-
0037154885
-
Retrograde support of neuronal survival without retrograde transport of nerve growth factor
-
MacInnis BL, Campenot RB (2002) Retrograde support of neuronal survival without retrograde transport of nerve growth factor. Science 295:1536-1539
-
(2002)
Science
, vol.295
, pp. 1536-1539
-
-
MacInnis, B.L.1
Campenot, R.B.2
-
12
-
-
0030861966
-
Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures
-
Senger DL, Campenot RB (1997) Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures. J Cell Biol 138:411-421
-
(1997)
J Cell Biol
, vol.138
, pp. 411-421
-
-
Senger, D.L.1
Campenot, R.B.2
-
13
-
-
0030059338
-
Signaling from synapse to nucleus: Postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity
-
Deisseroth K, Bito H, Tsien RW (1996) Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity. Neuron 16:89-101
-
(1996)
Neuron
, vol.16
, pp. 89-101
-
-
Deisseroth, K.1
Bito, H.2
Tsien, R.W.3
-
14
-
-
0027926582
-
Cell signalling. A tale of two messengers
-
Berridge MJ (1993) Cell signalling. A tale of two messengers. Nature 365:388-389
-
(1993)
Nature
, vol.365
, pp. 388-389
-
-
Berridge, M.J.1
-
15
-
-
0028117753
-
On the nature and differential distribution of mRNAs in hippocampal neurites: Implications for neuronal functioning
-
Miyashiro K, Dichter M, Eberwine J (1994) On the nature and differential distribution of mRNAs in hippocampal neurites: implications for neuronal functioning. Proc Natl Acad Sci U S A 91:10800-10804
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 10800-10804
-
-
Miyashiro, K.1
Dichter, M.2
Eberwine, J.3
-
16
-
-
9144273965
-
Axoplasmic importins enable retrograde injury signaling in lesioned nerve
-
Hanz S, Perlson E, Willis D, Zheng JQ, Massarwa R, Huerta JJ, Koltzenburg M, Kohler M, van-Minnen J, Twiss JL (2003) Axoplasmic importins enable retrograde injury signaling in lesioned nerve. Neuron 40:1095-1104
-
(2003)
Neuron
, vol.40
, pp. 1095-1104
-
-
Hanz, S.1
Perlson, E.2
Willis, D.3
Zheng, J.Q.4
Massarwa, R.5
Huerta, J.J.6
Koltzenburg, M.7
Kohler, M.8
van-Minnen, J.9
Twiss, J.L.10
-
17
-
-
10444251033
-
Synapse to nucleus signaling during long-term synaptic plasticity; a role for the classical active nuclear import pathway
-
Thompson KR, Otis KO, Chen DY, Zhao Y, O'Dell TJ, Martin KC (2004) Synapse to nucleus signaling during long-term synaptic plasticity; a role for the classical active nuclear import pathway. Neuron 44:997-1009
-
(2004)
Neuron
, vol.44
, pp. 997-1009
-
-
Thompson, K.R.1
Otis, K.O.2
Chen, D.Y.3
Zhao, Y.4
O'Dell, T.J.5
Martin, K.C.6
-
18
-
-
0141653866
-
NF-kappa B functions in synaptic signaling and behavior
-
Meffert MK, Chang JM, Wiltgen BJ, Fanselow MS, Baltimore D (2003) NF-kappa B functions in synaptic signaling and behavior. Nat Neurosci 6:1072-1078
-
(2003)
Nat Neurosci
, vol.6
, pp. 1072-1078
-
-
Meffert, M.K.1
Chang, J.M.2
Wiltgen, B.J.3
Fanselow, M.S.4
Baltimore, D.5
-
19
-
-
0037806030
-
Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons
-
Graef IA, Wang F, Charron F, Chen L, Neilson J, Tessier-Lavigne M, Crabtree GR (2003) Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell 113:657-670
-
(2003)
Cell
, vol.113
, pp. 657-670
-
-
Graef, I.A.1
Wang, F.2
Charron, F.3
Chen, L.4
Neilson, J.5
Tessier-Lavigne, M.6
Crabtree, G.R.7
-
20
-
-
0037403039
-
p75 neurotrophin receptor mediates neurotrophin activation of NF-kappa B and induction of iNOS expression in P19 neurons
-
Burke MA, Bothwell M (2003) p75 neurotrophin receptor mediates neurotrophin activation of NF-kappa B and induction of iNOS expression in P19 neurons. J Neurobiol 55:191-203
-
(2003)
J Neurobiol
, vol.55
, pp. 191-203
-
-
Burke, M.A.1
Bothwell, M.2
-
21
-
-
0041835836
-
Brain-derived neurotrophic factor activation of NFAT (nuclear factor of activated T-cells)-dependent transcription: A role for the transcription factor NFATc4 in neurotrophin-mediated gene expression
-
Groth RD, Mermelstein PG (2003) Brain-derived neurotrophic factor activation of NFAT (nuclear factor of activated T-cells)-dependent transcription: a role for the transcription factor NFATc4 in neurotrophin-mediated gene expression. J Neurosci 23:8125-8134
-
(2003)
J Neurosci
, vol.23
, pp. 8125-8134
-
-
Groth, R.D.1
Mermelstein, P.G.2
-
22
-
-
0035490884
-
The endocytic pathway: A mosaic of domains
-
Gruenberg J (2001) The endocytic pathway: a mosaic of domains. Nat Rev Mol Cell Biol 2:721-730
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 721-730
-
-
Gruenberg, J.1
-
23
-
-
33644764063
-
Ligands for clathrinmediated endocytosis are differentially sorted into distinct populations of early endosomes
-
Lakadamyali M, Rust MJ, Zhuang X (2006) Ligands for clathrinmediated endocytosis are differentially sorted into distinct populations of early endosomes. Cell 124:997-1009
-
(2006)
Cell
, vol.124
, pp. 997-1009
-
-
Lakadamyali, M.1
Rust, M.J.2
Zhuang, X.3
-
24
-
-
27844435600
-
Minireview: Recent developments in the regulation of glucose transporter-4 traffic: new signals, locations, and partners
-
Ishiki M, Klip A (2005) Minireview: recent developments in the regulation of glucose transporter-4 traffic: new signals, locations, and partners. Endocrinology 146:5071-5078
-
(2005)
Endocrinology
, vol.146
, pp. 5071-5078
-
-
Ishiki, M.1
Klip, A.2
-
25
-
-
0037119944
-
Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake
-
Meier O, Boucke K, Hammer SV, Keller S, Stidwill RP, Hemmi S, Greber UF (2002) Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake. J Cell Biol 158:1119-1131
-
(2002)
J Cell Biol
, vol.158
, pp. 1119-1131
-
-
Meier, O.1
Boucke, K.2
Hammer, S.V.3
Keller, S.4
Stidwill, R.P.5
Hemmi, S.6
Greber, U.F.7
-
26
-
-
4544375506
-
Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic
-
Pelkmans L, Burli T, Zerial M, Helenius A (2004) Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic. Cell 118:767-780
-
(2004)
Cell
, vol.118
, pp. 767-780
-
-
Pelkmans, L.1
Burli, T.2
Zerial, M.3
Helenius, A.4
-
27
-
-
0025359062
-
Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body
-
Felder S, Miller K, Moehren G, Ullrich A, Schlessinger J, Hopkins CR (1990) Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body. Cell 61:623-634
-
(1990)
Cell
, vol.61
, pp. 623-634
-
-
Felder, S.1
Miller, K.2
Moehren, G.3
Ullrich, A.4
Schlessinger, J.5
Hopkins, C.R.6
-
28
-
-
0141433284
-
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
-
Petiot A, Faure J, Stenmark H, Gruenberg J (2003) PI3P signaling regulates receptor sorting but not transport in the endosomal pathway. J Cell Biol 162:971-979
-
(2003)
J Cell Biol
, vol.162
, pp. 971-979
-
-
Petiot, A.1
Faure, J.2
Stenmark, H.3
Gruenberg, J.4
-
29
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
Vieira AV, Lamaze C, Schmid SL (1996) Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274:2086-2089
-
(1996)
Science
, vol.274
, pp. 2086-2089
-
-
Vieira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
31
-
-
4744360232
-
Role of rab5 in EGF receptor-mediated signal transduction
-
Barbieri MA, Fernandez-Pol S, Hunker C, Horazdovsky BH, Stahl PD (2004) Role of rab5 in EGF receptor-mediated signal transduction. Eur J Cell Biol 83:305-314
-
(2004)
Eur J Cell Biol
, vol.83
, pp. 305-314
-
-
Barbieri, M.A.1
Fernandez-Pol, S.2
Hunker, C.3
Horazdovsky, B.H.4
Stahl, P.D.5
-
32
-
-
0034676451
-
The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5
-
Lanzetti L, Rybin V, Malabarba MG, Christoforidis S, Scita G, Zerial M, Di Fiore PP (2000) The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5. Nature 408:374-377
-
(2000)
Nature
, vol.408
, pp. 374-377
-
-
Lanzetti, L.1
Rybin, V.2
Malabarba, M.G.3
Christoforidis, S.4
Scita, G.5
Zerial, M.6
Di Fiore, P.P.7
-
33
-
-
33644869303
-
Rab7 activity affects epidermal growth factor: Epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome
-
Ceresa BP, Bahr SJ (2006) Rab7 activity affects epidermal growth factor: epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome. J Biol Chem 281:1099-1106
-
(2006)
J Biol Chem
, vol.281
, pp. 1099-1106
-
-
Ceresa, B.P.1
Bahr, S.J.2
-
34
-
-
0348049831
-
Mechanisms controlling EGF receptor endocytosis and degradation
-
Dikic I (2003) Mechanisms controlling EGF receptor endocytosis and degradation. Biochem Soc Trans 31:1178-1181
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 1178-1181
-
-
Dikic, I.1
-
35
-
-
0036094538
-
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
-
Raiborg C, Bache KG, Gillooly DJ,Madshus IH, Stang E, Stenmark H (2002) Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat Cell Biol 4:394-398
-
(2002)
Nat Cell Biol
, vol.4
, pp. 394-398
-
-
Raiborg, C.1
Bache, K.G.2
Gillooly, D.J.3
Madshus, I.H.4
Stang, E.5
Stenmark, H.6
-
36
-
-
0028849793
-
Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain
-
Komada M, Kitamura N (1995) Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain. Mol Cell Biol 15:6213-6221
-
(1995)
Mol Cell Biol
, vol.15
, pp. 6213-6221
-
-
Komada, M.1
Kitamura, N.2
-
37
-
-
0036037283
-
Phosphorylation of Hrs downstream of the epidermal growth factor receptor
-
Bache KG, Raiborg C, Mehlum A, Madshus IH, Stenmark H (2002) Phosphorylation of Hrs downstream of the epidermal growth factor receptor. Eur J Biochem 269:3881-3887
-
(2002)
Eur J Biochem
, vol.269
, pp. 3881-3887
-
-
Bache, K.G.1
Raiborg, C.2
Mehlum, A.3
Madshus, I.H.4
Stenmark, H.5
-
38
-
-
0242382659
-
The UIM domain of Hrs couples receptor sorting to vesicle formation
-
Urbe S, Sachse M, Row PE, Preisinger C, Barr FA, Strous G, Klumperman J, Clague MJ (2003) The UIM domain of Hrs couples receptor sorting to vesicle formation. J Cell Sci 116:4169-4179
-
(2003)
J Cell Sci
, vol.116
, pp. 4169-4179
-
-
Urbe, S.1
Sachse, M.2
Row, P.E.3
Preisinger, C.4
Barr, F.A.5
Strous, G.6
Klumperman, J.7
Clague, M.J.8
-
39
-
-
0035958546
-
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I
-
Katzmann DJ, Babst M, Emr SD (2001) Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106:145-155
-
(2001)
Cell
, vol.106
, pp. 145-155
-
-
Katzmann, D.J.1
Babst, M.2
Emr, S.D.3
-
40
-
-
0037596749
-
TSG101 interaction with HRS mediates endosomal trafficking and receptor downregulation
-
Lu Q, Hope LW, Brasch M, Reinhard C, Cohen SN (2003) TSG101 interaction with HRS mediates endosomal trafficking and receptor downregulation. Proc Natl Acad Sci USA 100:7626-7631
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7626-7631
-
-
Lu, Q.1
Hope, L.W.2
Brasch, M.3
Reinhard, C.4
Cohen, S.N.5
-
41
-
-
0037216740
-
Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues
-
Wagner KU, Krempler A, Qi Y, Park K, Henry MD, Triplett AA, Riedlinger G, Rucker IE, Hennighausen L (2003) Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues. Mol Cell Biol 23:150-162
-
(2003)
Mol Cell Biol
, vol.23
, pp. 150-162
-
-
Wagner, K.U.1
Krempler, A.2
Qi, Y.3
Park, K.4
Henry, M.D.5
Triplett, A.A.6
Riedlinger, G.7
Rucker, I.E.8
Hennighausen, L.9
-
42
-
-
0035854367
-
Endocytosis and signaling: An inseparable partnership
-
Di Fiore PP, De Camilli P (2001) Endocytosis and signaling: an inseparable partnership. Cell 106:1-4
-
(2001)
Cell
, vol.106
, pp. 1-4
-
-
Di Fiore, P.P.1
De Camilli, P.2
-
43
-
-
4344629687
-
Continual expression of Rab5 (Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity
-
Dinneen JL, Ceresa BP (2004) Continual expression of Rab5 (Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity. Traffic 5:606-615
-
(2004)
Traffic
, vol.5
, pp. 606-615
-
-
Dinneen, J.L.1
Ceresa, B.P.2
-
44
-
-
23744498092
-
HRS inhibits EGF receptor signaling in the RT4 rat schwannoma cell line
-
Scoles DR, Qin Y, Nguyen V, Gutmann DH, Pulst SM (2005) HRS inhibits EGF receptor signaling in the RT4 rat schwannoma cell line. Biochem Biophys Res Commun 335:385-392
-
(2005)
Biochem Biophys Res Commun
, vol.335
, pp. 385-392
-
-
Scoles, D.R.1
Qin, Y.2
Nguyen, V.3
Gutmann, D.H.4
Pulst, S.M.5
-
45
-
-
33644769212
-
Endocytosis conducts the cell signaling orchestra
-
Polo S, Di Fiore PP (2006) Endocytosis conducts the cell signaling orchestra. Cell 124:897-900
-
(2006)
Cell
, vol.124
, pp. 897-900
-
-
Polo, S.1
Di Fiore, P.P.2
-
46
-
-
0020577206
-
Binding and degradation of nerve growth factor by PC12 pheochromocytoma cells
-
Layer PG, Shooter EM (1983) Binding and degradation of nerve growth factor by PC12 pheochromocytoma cells. J Biol Chem 258:3012-3018
-
(1983)
J Biol Chem
, vol.258
, pp. 3012-3018
-
-
Layer, P.G.1
Shooter, E.M.2
-
47
-
-
14644394937
-
Differential endocytic sorting of p75NTR and TrkA in response to NGF: A role for late endosomes in TrkA trafficking
-
Saxena S, Howe CL, Cosgaya JM, Steiner P, Hirling H, Chan JR, Weis J, Kruttgen A (2005) Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking. Mol Cell Neurosci 28:571-587
-
(2005)
Mol Cell Neurosci
, vol.28
, pp. 571-587
-
-
Saxena, S.1
Howe, C.L.2
Cosgaya, J.M.3
Steiner, P.4
Hirling, H.5
Chan, J.R.6
Weis, J.7
Kruttgen, A.8
-
48
-
-
0035819073
-
NGF signaling from clathrin-coated vesicles: Evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway
-
Howe CL, Valletta JS, Rusnak AS, Mobley WC (2001) NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway. Neuron 32:801-814
-
(2001)
Neuron
, vol.32
, pp. 801-814
-
-
Howe, C.L.1
Valletta, J.S.2
Rusnak, A.S.3
Mobley, W.C.4
-
49
-
-
2942659327
-
Differences in the surface binding and endocytosis of neurotrophins by p75NTR
-
Saxena S, Howe CL, Cosgaya JM, Hu M, Weis J, Kruttgen A (2004) Differences in the surface binding and endocytosis of neurotrophins by p75NTR. Mol Cell Neurosci 26:292-307
-
(2004)
Mol Cell Neurosci
, vol.26
, pp. 292-307
-
-
Saxena, S.1
Howe, C.L.2
Cosgaya, J.M.3
Hu, M.4
Weis, J.5
Kruttgen, A.6
-
50
-
-
0037899137
-
NGF signaling in sensory neurons: Evidence that early endosomes carry NGF retrograde signals
-
Delcroix JD, Valletta JS, Wu C, Hunt SJ, Kowal AS, Mobley WC (2003) NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals. Neuron 39:69-84
-
(2003)
Neuron
, vol.39
, pp. 69-84
-
-
Delcroix, J.D.1
Valletta, J.S.2
Wu, C.3
Hunt, S.J.4
Kowal, A.S.5
Mobley, W.C.6
-
51
-
-
19444366758
-
Pincher-mediated macroendocytosis underlies retrograde signaling by neurotrophin receptors
-
Valdez G, Akmentin W, Philippidou P, Kuruvilla R, Ginty DD, Halegoua S (2005) Pincher-mediated macroendocytosis underlies retrograde signaling by neurotrophin receptors. J Neurosci 25:5236-5247
-
(2005)
J Neurosci
, vol.25
, pp. 5236-5247
-
-
Valdez, G.1
Akmentin, W.2
Philippidou, P.3
Kuruvilla, R.4
Ginty, D.D.5
Halegoua, S.6
-
52
-
-
28044444522
-
The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA
-
Saxena S, Bucci C, Weis J, Kruttgen A (2005) The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA. J Neurosci 25:10930-10940
-
(2005)
J Neurosci
, vol.25
, pp. 10930-10940
-
-
Saxena, S.1
Bucci, C.2
Weis, J.3
Kruttgen, A.4
-
53
-
-
0026779475
-
Axonal and dendritic endocytic pathways in cultured neurons
-
Parton RG, Simons K, Dotti CG (1992) Axonal and dendritic endocytic pathways in cultured neurons. J Cell Biol 119:123-137
-
(1992)
J Cell Biol
, vol.119
, pp. 123-137
-
-
Parton, R.G.1
Simons, K.2
Dotti, C.G.3
-
54
-
-
0020322468
-
Binding, internalization, and retrograde transport of 125I-nerve growth factor in cultured rat sympathetic neurons
-
Claude P, Hawrot E, Dunis DA, Campenot RB (1982) Binding, internalization, and retrograde transport of 125I-nerve growth factor in cultured rat sympathetic neurons. J Neurosci 2:431-442
-
(1982)
J Neurosci
, vol.2
, pp. 431-442
-
-
Claude, P.1
Hawrot, E.2
Dunis, D.A.3
Campenot, R.B.4
-
55
-
-
0031017336
-
Retrograde transport and steady-state distribution of 125I-nerve growth factor in rat sympathetic neurons in compartmented cultures
-
Ure DR, Campenot RB (1997) Retrograde transport and steady-state distribution of 125I-nerve growth factor in rat sympathetic neurons in compartmented cultures. J Neurosci 17:1282-1290
-
(1997)
J Neurosci
, vol.17
, pp. 1282-1290
-
-
Ure, D.R.1
Campenot, R.B.2
-
56
-
-
0036341207
-
Signal transduction and endocytosis: Close encounters of many kinds
-
Sorkin A, Von Zastrow M (2002) Signal transduction and endocytosis: close encounters of many kinds. Nat Rev Mol Cell Biol 3:600-614
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 600-614
-
-
Sorkin, A.1
Von Zastrow, M.2
-
57
-
-
0037096094
-
High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors
-
Bhattacharyya A, Watson FL, Pomeroy SL, Zhang YZ, Stiles CD, Segal RA (2002) High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors. J Neurobiol 51:302-312
-
(2002)
J Neurobiol
, vol.51
, pp. 302-312
-
-
Bhattacharyya, A.1
Watson, F.L.2
Pomeroy, S.L.3
Zhang, Y.Z.4
Stiles, C.D.5
Segal, R.A.6
-
58
-
-
0035911147
-
A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment
-
Wunderlich W, Fialka I, Teis D, Alpi A, Pfeifer A, Parton RG, Lottspeich F, Huber LA (2001) A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment. J Cell Biol 152:765-776
-
(2001)
J Cell Biol
, vol.152
, pp. 765-776
-
-
Wunderlich, W.1
Fialka, I.2
Teis, D.3
Alpi, A.4
Pfeifer, A.5
Parton, R.G.6
Lottspeich, F.7
Huber, L.A.8
-
59
-
-
0035031938
-
Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF
-
Oksvold MP, Skarpen E, Wierod L, Paulsen RE, Huitfeldt HS (2001) Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF. Eur J Cell Biol 80:285-294
-
(2001)
Eur J Cell Biol
, vol.80
, pp. 285-294
-
-
Oksvold, M.P.1
Skarpen, E.2
Wierod, L.3
Paulsen, R.E.4
Huitfeldt, H.S.5
-
60
-
-
0032928879
-
Caveolin interacts with Trk A and p75(NTR) and regulates neurotrophin signaling pathways
-
Bilderback TR, Gazula VR, Lisanti MP, Dobrowsky RT (1999) Caveolin interacts with Trk A and p75(NTR) and regulates neurotrophin signaling pathways. J Biol Chem 274:257-263
-
(1999)
J Biol Chem
, vol.274
, pp. 257-263
-
-
Bilderback, T.R.1
Gazula, V.R.2
Lisanti, M.P.3
Dobrowsky, R.T.4
-
61
-
-
0033579437
-
Nerve growth factor signaling in caveolae-like domains at the plasma membrane
-
Huang CS, Zhou J, Feng AK, Lynch CC, Klumperman J, DeArmond SJ, Mobley WC (1999) Nerve growth factor signaling in caveolae-like domains at the plasma membrane. J Biol Chem 274:36707-36714
-
(1999)
J Biol Chem
, vol.274
, pp. 36707-36714
-
-
Huang, C.S.1
Zhou, J.2
Feng, A.K.3
Lynch, C.C.4
Klumperman, J.5
DeArmond, S.J.6
Mobley, W.C.7
-
62
-
-
0034532063
-
PC12 cells have caveolae that contain TrkA. Caveolae-disrupting drugs inhibit nerve growth factor-induced, but not epidermal growth factor-induced, MAPK phosphorylation
-
Peiro S, Comella JX, Enrich C, Martin-Zanca D, Rocamora N (2000) PC12 cells have caveolae that contain TrkA. Caveolae-disrupting drugs inhibit nerve growth factor-induced, but not epidermal growth factor-induced, MAPK phosphorylation. J Biol Chem 275:37846-37852
-
(2000)
J Biol Chem
, vol.275
, pp. 37846-37852
-
-
Peiro, S.1
Comella, J.X.2
Enrich, C.3
Martin-Zanca, D.4
Rocamora, N.5
-
63
-
-
14544306526
-
Clathrin-independent endocytosis of ubiquitinated cargos
-
Sigismund S,Woelk T, Puri C, Maspero E, Tacchetti C, Transidico P, Di Fiore PP, Polo S (2005) Clathrin-independent endocytosis of ubiquitinated cargos. Proc Natl Acad Sci USA 102:2760-2765
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2760-2765
-
-
Sigismund, S.1
Woelk, T.2
Puri, C.3
Maspero, E.4
Tacchetti, C.5
Transidico, P.6
Di Fiore, P.P.7
Polo, S.8
-
64
-
-
0033216248
-
Characterization of an NGFP-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons
-
Tsui-Pierchala BA, Ginty DD (1999) Characterization of an NGFP-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons. J Neurosci 19:8207-8218
-
(1999)
J Neurosci
, vol.19
, pp. 8207-8218
-
-
Tsui-Pierchala, B.A.1
Ginty, D.D.2
-
65
-
-
0037547112
-
Ligand-induced internalization of the p75 neurotrophin receptor: A slow route to the signaling endosome
-
Bronfman FC, Tcherpakov M, Jovin TM, Fainzilber M (2003) Ligand-induced internalization of the p75 neurotrophin receptor: a slow route to the signaling endosome. J Neurosci 23:3209-3220
-
(2003)
J Neurosci
, vol.23
, pp. 3209-3220
-
-
Bronfman, F.C.1
Tcherpakov, M.2
Jovin, T.M.3
Fainzilber, M.4
-
66
-
-
0027966170
-
Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells
-
Barker PA, Shooter EM (1994) Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells. Neuron 13:203-215
-
(1994)
Neuron
, vol.13
, pp. 203-215
-
-
Barker, P.A.1
Shooter, E.M.2
-
67
-
-
0033766404
-
Sustained activation of insulin receptors internalized in GLUT4 vesicles of insulin-stimulated skeletal muscle
-
Dombrowski L, Faure R, Marette A (2000) Sustained activation of insulin receptors internalized in GLUT4 vesicles of insulin-stimulated skeletal muscle. Diabetes 49:1772-1782
-
(2000)
Diabetes
, vol.49
, pp. 1772-1782
-
-
Dombrowski, L.1
Faure, R.2
Marette, A.3
-
68
-
-
28644440548
-
A novel endocytic recycling signal distinguishes biological responses of Trk neurotrophin receptors
-
Chen ZY, Ieraci A, Tanowitz M, Lee FS (2005) A novel endocytic recycling signal distinguishes biological responses of Trk neurotrophin receptors. Mol Biol Cell 16:5761-5772
-
(2005)
Mol Biol Cell
, vol.16
, pp. 5761-5772
-
-
Chen, Z.Y.1
Ieraci, A.2
Tanowitz, M.3
Lee, F.S.4
-
69
-
-
0031730287
-
Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis
-
Zapf-Colby A, Olefsky JM (1998) Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis. Endocrinology 139:3232-3240
-
(1998)
Endocrinology
, vol.139
, pp. 3232-3240
-
-
Zapf-Colby, A.1
Olefsky, J.M.2
-
70
-
-
0037931402
-
Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: Distribution of homo- and heterodimers depends on relative HER2 levels
-
Hendriks BS, Opresko LK, Wiley HS, Lauffenburger D (2003) Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels. J Biol Chem 278:23343-23351
-
(2003)
J Biol Chem
, vol.278
, pp. 23343-23351
-
-
Hendriks, B.S.1
Opresko, L.K.2
Wiley, H.S.3
Lauffenburger, D.4
-
71
-
-
0141530936
-
HER2-mediated effects on EGFR endosomal sorting: Analysis of biophysical mechanisms
-
Hendriks BS, Wiley HS, Lauffenburger D (2003) HER2-mediated effects on EGFR endosomal sorting: analysis of biophysical mechanisms. Biophys J 85:2732-2745
-
(2003)
Biophys J
, vol.85
, pp. 2732-2745
-
-
Hendriks, B.S.1
Wiley, H.S.2
Lauffenburger, D.3
-
72
-
-
0042164216
-
Individual and combined effects of TrkA and p75NTR nerve growth factor receptors. A role for the high affinity receptor site
-
Lad SP, Peterson DA, Bradshaw RA, Neet KE (2003) Individual and combined effects of TrkA and p75NTR nerve growth factor receptors. A role for the high affinity receptor site. J Biol Chem 278:24808-24817
-
(2003)
J Biol Chem
, vol.278
, pp. 24808-24817
-
-
Lad, S.P.1
Peterson, D.A.2
Bradshaw, R.A.3
Neet, K.E.4
-
73
-
-
0034255428
-
Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation
-
Zhang Y, Moheban DB, Conway BR, Bhattacharyya A, Segal RA (2000) Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation. J Neurosci 20:5671-5678
-
(2000)
J Neurosci
, vol.20
, pp. 5671-5678
-
-
Zhang, Y.1
Moheban, D.B.2
Conway, B.R.3
Bhattacharyya, A.4
Segal, R.A.5
-
74
-
-
27344449759
-
p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation
-
Makkerh JP, Ceni C, Auld DS, Vaillancourt F, Dorval G, Barker PA (2005) p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation. EMBO Rep 6:936-941
-
(2005)
EMBO Rep
, vol.6
, pp. 936-941
-
-
Makkerh, J.P.1
Ceni, C.2
Auld, D.S.3
Vaillancourt, F.4
Dorval, G.5
Barker, P.A.6
-
75
-
-
26944484011
-
Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling
-
Geetha T, Jiang J, Wooten MW (2005) Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling. Mol Cell 20:301-312
-
(2005)
Mol Cell
, vol.20
, pp. 301-312
-
-
Geetha, T.1
Jiang, J.2
Wooten, M.W.3
-
76
-
-
33646396185
-
Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination
-
Arevalo JC, Waite J, Rajagopal R, Beyna M, Chen ZY, Lee FS, Chao MV (2006) Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination. Neuron 50:549-559
-
(2006)
Neuron
, vol.50
, pp. 549-559
-
-
Arevalo, J.C.1
Waite, J.2
Rajagopal, R.3
Beyna, M.4
Chen, Z.Y.5
Lee, F.S.6
Chao, M.V.7
-
77
-
-
0033081042
-
Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR
-
Bibel M, Hoppe E, Barde YA (1999) Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR. Embo J 18:616-622
-
(1999)
Embo J
, vol.18
, pp. 616-622
-
-
Bibel, M.1
Hoppe, E.2
Barde, Y.A.3
-
78
-
-
4444302767
-
c-Cbl binds to tyrosine-phosphorylated neurotrophin receptor p75 and induces its ubiquitination
-
Ohrt T, Mancini A, Tamura T, Niedenthal R (2004) c-Cbl binds to tyrosine-phosphorylated neurotrophin receptor p75 and induces its ubiquitination. Cell Signal 16:1291-1298
-
(2004)
Cell Signal
, vol.16
, pp. 1291-1298
-
-
Ohrt, T.1
Mancini, A.2
Tamura, T.3
Niedenthal, R.4
-
79
-
-
11144225699
-
GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi network
-
Scott PM, Bilodeau PS, Zhdankina O, Winistorfer SC, Hauglund MJ, Allaman MM, Kearney WR, Robertson AD, Boman AL, Piper RC (2004) GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi network. Nat Cell Biol 6:252-259
-
(2004)
Nat Cell Biol
, vol.6
, pp. 252-259
-
-
Scott, P.M.1
Bilodeau, P.S.2
Zhdankina, O.3
Winistorfer, S.C.4
Hauglund, M.J.5
Allaman, M.M.6
Kearney, W.R.7
Robertson, A.D.8
Boman, A.L.9
Piper, R.C.10
-
80
-
-
0019781601
-
A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer disease
-
Appel SH (1981) A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer disease. Ann Neurol 10:499-505
-
(1981)
Ann Neurol
, vol.10
, pp. 499-505
-
-
Appel, S.H.1
-
82
-
-
2942591228
-
Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
-
Cooper JD, Salehi A, Delcroix JD, Howe CL, Belichenko PV, Chua-Couzens J, Kilbridge JF, Carlson EJ, Epstein CJ, Mobley WC (2001) Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proc Natl Acad Sci USA 98:10439-10444
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10439-10444
-
-
Cooper, J.D.1
Salehi, A.2
Delcroix, J.D.3
Howe, C.L.4
Belichenko, P.V.5
Chua-Couzens, J.6
Kilbridge, J.F.7
Carlson, E.J.8
Epstein, C.J.9
Mobley, W.C.10
-
83
-
-
0022486717
-
Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections
-
Hefti F (1986) Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections. J Neurosci 6:2155-2162
-
(1986)
J Neurosci
, vol.6
, pp. 2155-2162
-
-
Hefti, F.1
-
84
-
-
0030799383
-
Disruption of a single allele of the nerve growth factor gene results in atrophy of basal forebrain cholinergic neurons and memory deficits
-
Chen KS, Nishimura MC, Armanini MP, Crowley C, Spencer SD, Phillips HS (1997) Disruption of a single allele of the nerve growth factor gene results in atrophy of basal forebrain cholinergic neurons and memory deficits. J Neurosci 17:7288-7296
-
(1997)
J Neurosci
, vol.17
, pp. 7288-7296
-
-
Chen, K.S.1
Nishimura, M.C.2
Armanini, M.P.3
Crowley, C.4
Spencer, S.D.5
Phillips, H.S.6
-
85
-
-
0034612256
-
Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice
-
Capsoni S, Ugolini G, Comparini A, Ruberti F, Berardi N, Cattaneo A (2000) Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice. Proc Natl Acad Sci USA 97:6826-6831
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6826-6831
-
-
Capsoni, S.1
Ugolini, G.2
Comparini, A.3
Ruberti, F.4
Berardi, N.5
Cattaneo, A.6
-
86
-
-
21044458854
-
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease
-
Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, Patel P, Blesch A, Vahlsing HL, Ho G (2005) A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med 11:551-555
-
(2005)
Nat Med
, vol.11
, pp. 551-555
-
-
Tuszynski, M.H.1
Thal, L.2
Pay, M.3
Salmon, D.P.4
HS, U.5
Bakay, R.6
Patel, P.7
Blesch, A.8
Vahlsing, H.L.9
Ho, G.10
-
87
-
-
20044385920
-
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease
-
Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS (2005) Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science 307:1282-1288
-
(2005)
Science
, vol.307
, pp. 1282-1288
-
-
Stokin, G.B.1
Lillo, C.2
Falzone, T.L.3
Brusch, R.G.4
Rockenstein, E.5
Mount, S.L.6
Raman, R.7
Davies, P.8
Masliah, E.9
Williams, D.S.10
-
88
-
-
33745512851
-
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration
-
Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP (2006) Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron 51:29-42
-
(2006)
Neuron
, vol.51
, pp. 29-42
-
-
Salehi, A.1
Delcroix, J.D.2
Belichenko, P.V.3
Zhan, K.4
Wu, C.5
Valletta, J.S.6
Takimoto-Kimura, R.7
Kleschevnikov, A.M.8
Sambamurti, K.9
Chung, P.P.10
-
89
-
-
0035818998
-
Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP
-
Kamal A, Almenar-Queralt A, LeBlanc JF, Roberts EA, Goldstein LS (2001) Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Nature 414:643-648
-
(2001)
Nature
, vol.414
, pp. 643-648
-
-
Kamal, A.1
Almenar-Queralt, A.2
LeBlanc, J.F.3
Roberts, E.A.4
Goldstein, L.S.5
-
90
-
-
20044396527
-
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: Revisited
-
Lazarov O, Morfini GA, Lee EB, Farah MH, Szodorai A, DeBoer SR, Koliatsos VE, Kins S, Lee VM, Wong PC (2005) Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. J Neurosci 25:2386-2395
-
(2005)
J Neurosci
, vol.25
, pp. 2386-2395
-
-
Lazarov, O.1
Morfini, G.A.2
Lee, E.B.3
Farah, M.H.4
Szodorai, A.5
DeBoer, S.R.6
Koliatsos, V.E.7
Kins, S.8
Lee, V.M.9
Wong, P.C.10
-
91
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
Gauthier LR, Charrin BC, Borrell-Pages M, Dompierre JP, Rangone H, Cordelieres FP, De Mey J, MacDonald ME, Lessmann V, Humbert S (2004) Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118:127-138
-
(2004)
Cell
, vol.118
, pp. 127-138
-
-
Gauthier, L.R.1
Charrin, B.C.2
Borrell-Pages, M.3
Dompierre, J.P.4
Rangone, H.5
Cordelieres, F.P.6
De Mey, J.7
MacDonald, M.E.8
Lessmann, V.9
Humbert, S.10
|