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Volumn 16, Issue 4, 2007, Pages 945-973

Current Immunotherapeutic Strategies in Malignant Melanoma

Author keywords

[No Author keywords available]

Indexed keywords

ALLOVECTIN 7; ANTINEOPLASTIC AGENT; CANCER VACCINE; CP 675206; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DENILEUKIN DIFTITOX; HEAT SHOCK PROTEIN; INTERLEUKIN 12; INTERLEUKIN 2; IPILIMUMAB; MELANOMA ANTIGEN; MELPHALAN; PF 33512676; RECOMBINANT ALPHA2B INTERFERON; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR STIMULATING AGENT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 36049047752     PISSN: 10553207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.soc.2007.07.010     Document Type: Review
Times cited : (4)

References (159)
  • 1
    • 0024411618 scopus 로고
    • Spontaneous regression of choroidal melanoma over 8 years
    • Chong C.A., Gregor R.J., Augsburger J.J., et al. Spontaneous regression of choroidal melanoma over 8 years. Retina 9 2 (1989) 136-138
    • (1989) Retina , vol.9 , Issue.2 , pp. 136-138
    • Chong, C.A.1    Gregor, R.J.2    Augsburger, J.J.3
  • 2
    • 0036905031 scopus 로고    scopus 로고
    • Spontaneous regression of metastatic cutaneous melanoma to the choroid
    • Shields C.L., Piccone M.R., Fung K.L., et al. Spontaneous regression of metastatic cutaneous melanoma to the choroid. Retina 22 6 (2002) 806-808
    • (2002) Retina , vol.22 , Issue.6 , pp. 806-808
    • Shields, C.L.1    Piccone, M.R.2    Fung, K.L.3
  • 3
    • 0035685394 scopus 로고    scopus 로고
    • Spontaneous regression of metastatic malignant melanoma of the parotid gland and neck lymph nodes: a case report and a review of the literature
    • King M., Spooner D., and Rowlands D.C. Spontaneous regression of metastatic malignant melanoma of the parotid gland and neck lymph nodes: a case report and a review of the literature. Clin Oncol (R Coll Radiol) 13 6 (2001) 466-469
    • (2001) Clin Oncol (R Coll Radiol) , vol.13 , Issue.6 , pp. 466-469
    • King, M.1    Spooner, D.2    Rowlands, D.C.3
  • 4
    • 0016176253 scopus 로고
    • BCG immunotherapy of malignant melanoma: summary of a seven-year experience
    • Morton D.L., Eilber F.R., Holmes E.C., et al. BCG immunotherapy of malignant melanoma: summary of a seven-year experience. Ann Surg 180 4 (1974) 635-643
    • (1974) Ann Surg , vol.180 , Issue.4 , pp. 635-643
    • Morton, D.L.1    Eilber, F.R.2    Holmes, E.C.3
  • 5
    • 0024554410 scopus 로고
    • The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens
    • Darrow T.L., Slingluff Jr. C.L., and Seigler H.F. The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens. J Immunol 142 9 (1989) 3329-3335
    • (1989) J Immunol , vol.142 , Issue.9 , pp. 3329-3335
    • Darrow, T.L.1    Slingluff Jr., C.L.2    Seigler, H.F.3
  • 6
    • 0026322151 scopus 로고
    • A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma
    • van der Bruggen P., Traversari C., Chomez P., et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 254 5038 (1991) 1643-1647
    • (1991) Science , vol.254 , Issue.5038 , pp. 1643-1647
    • van der Bruggen, P.1    Traversari, C.2    Chomez, P.3
  • 7
    • 0026531657 scopus 로고
    • Shared human melanoma antigens. Recognition by tumor-infiltrating lymphocytes in HLA-A2.1-transfected melanomas
    • Kawakami Y., Zakut R., Topalian S.L., et al. Shared human melanoma antigens. Recognition by tumor-infiltrating lymphocytes in HLA-A2.1-transfected melanomas. J Immunol 148 2 (1992) 638-643
    • (1992) J Immunol , vol.148 , Issue.2 , pp. 638-643
    • Kawakami, Y.1    Zakut, R.2    Topalian, S.L.3
  • 8
    • 0026733707 scopus 로고
    • Recognition of shared melanoma antigens by human tumor-infiltrating lymphocytes
    • Topalian S.L., Hom S.S., Kawakami Y., et al. Recognition of shared melanoma antigens by human tumor-infiltrating lymphocytes. J Immunother 12 3 (1992) 203-206
    • (1992) J Immunother , vol.12 , Issue.3 , pp. 203-206
    • Topalian, S.L.1    Hom, S.S.2    Kawakami, Y.3
  • 9
    • 0027459260 scopus 로고
    • Specific release of cytokines by lymphocytes infiltrating human melanomas in response to shared melanoma antigens
    • Hom S.S., Schwartzentruber D.J., Rosenberg S.A., et al. Specific release of cytokines by lymphocytes infiltrating human melanomas in response to shared melanoma antigens. J Immunother 13 1 (1993) 18-30
    • (1993) J Immunother , vol.13 , Issue.1 , pp. 18-30
    • Hom, S.S.1    Schwartzentruber, D.J.2    Rosenberg, S.A.3
  • 10
    • 0027214726 scopus 로고
    • Identification of human melanoma peptides recognized by class I restricted tumor infiltrating T lymphocytes
    • Storkus W.J., Zeh III H.J., Maeurer M.J., et al. Identification of human melanoma peptides recognized by class I restricted tumor infiltrating T lymphocytes. J Immunol 151 7 (1993) 3719-3727
    • (1993) J Immunol , vol.151 , Issue.7 , pp. 3719-3727
    • Storkus, W.J.1    Zeh III, H.J.2    Maeurer, M.J.3
  • 11
    • 0033103021 scopus 로고    scopus 로고
    • A new era for cancer immunotherapy based on the genes that encode cancer antigens
    • Rosenberg S.A. A new era for cancer immunotherapy based on the genes that encode cancer antigens. Immunity 10 3 (1999) 281-287
    • (1999) Immunity , vol.10 , Issue.3 , pp. 281-287
    • Rosenberg, S.A.1
  • 12
    • 12644276375 scopus 로고    scopus 로고
    • A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening
    • Chen Y.T., Scanlan M.J., Sahin U., et al. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc Natl Acad Sci USA 94 5 (1997) 1914-1918
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.5 , pp. 1914-1918
    • Chen, Y.T.1    Scanlan, M.J.2    Sahin, U.3
  • 13
    • 13344282077 scopus 로고
    • Human neoplasms elicit multiple specific immune responses in the autologous host
    • Sahin U., Tureci O., Schmitt H., et al. Human neoplasms elicit multiple specific immune responses in the autologous host. Proc Natl Acad Sci USA 92 25 (1995) 11810-11813
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.25 , pp. 11810-11813
    • Sahin, U.1    Tureci, O.2    Schmitt, H.3
  • 14
    • 0028304337 scopus 로고
    • Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines
    • Cox A.L., Skipper J., Chen Y., et al. Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines. Science 264 5159 (1994) 716-719
    • (1994) Science , vol.264 , Issue.5159 , pp. 716-719
    • Cox, A.L.1    Skipper, J.2    Chen, Y.3
  • 15
    • 0028023727 scopus 로고
    • Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene
    • Topalian S.L., Rivoltini L., Mancini M., et al. Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene. Proc Natl Acad Sci USA 91 20 (1994) 9461-9465
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.20 , pp. 9461-9465
    • Topalian, S.L.1    Rivoltini, L.2    Mancini, M.3
  • 16
    • 0032212445 scopus 로고    scopus 로고
    • Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2)
    • Parkhurst M.R., Fitzgerald E.B., Southwood S., et al. Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2). Cancer Res 58 21 (1998) 4895-4901
    • (1998) Cancer Res , vol.58 , Issue.21 , pp. 4895-4901
    • Parkhurst, M.R.1    Fitzgerald, E.B.2    Southwood, S.3
  • 17
    • 23944454145 scopus 로고    scopus 로고
    • Active antigen-specific immunotherapy of melanoma: from basic science to clinical investigation
    • Spagnoli G.C., Adamina M., Bolli M., et al. Active antigen-specific immunotherapy of melanoma: from basic science to clinical investigation. World J Surg 29 6 (2005) 692-699
    • (2005) World J Surg , vol.29 , Issue.6 , pp. 692-699
    • Spagnoli, G.C.1    Adamina, M.2    Bolli, M.3
  • 18
    • 0035095532 scopus 로고    scopus 로고
    • A listing of human tumor antigens recognized by T cells
    • Renkvist N., Castelli C., Robbins P.F., et al. A listing of human tumor antigens recognized by T cells. Cancer Immunol Immunother 50 1 (2001) 3-15
    • (2001) Cancer Immunol Immunother , vol.50 , Issue.1 , pp. 3-15
    • Renkvist, N.1    Castelli, C.2    Robbins, P.F.3
  • 19
    • 23144464171 scopus 로고    scopus 로고
    • Cancer/testis antigens, gametogenesis and cancer
    • Simpson A.J., Caballero O.L., Jungbluth A., et al. Cancer/testis antigens, gametogenesis and cancer. Nat Rev Cancer 5 8 (2005) 615-625
    • (2005) Nat Rev Cancer , vol.5 , Issue.8 , pp. 615-625
    • Simpson, A.J.1    Caballero, O.L.2    Jungbluth, A.3
  • 20
    • 33845328083 scopus 로고    scopus 로고
    • A causal role for the human tumor antigen preferentially expressed antigen of melanoma in cancer
    • Epping M.T., and Bernards R. A causal role for the human tumor antigen preferentially expressed antigen of melanoma in cancer. Cancer Res 66 22 (2006) 10639-10642
    • (2006) Cancer Res , vol.66 , Issue.22 , pp. 10639-10642
    • Epping, M.T.1    Bernards, R.2
  • 21
    • 0000812865 scopus 로고
    • Late results of the treatment of inoperable sarcoma by the mixed toxins of erysipelas and bacillus prodigiosus
    • Coley W.B. Late results of the treatment of inoperable sarcoma by the mixed toxins of erysipelas and bacillus prodigiosus. Am J Med Sci 131 (1906) 375-430
    • (1906) Am J Med Sci , vol.131 , pp. 375-430
    • Coley, W.B.1
  • 22
    • 0035139983 scopus 로고    scopus 로고
    • Danger signals: SOS to the immune system
    • Gallucci S., and Matzinger P. Danger signals: SOS to the immune system. Curr Opin Immunol 13 1 (2001) 114-119
    • (2001) Curr Opin Immunol , vol.13 , Issue.1 , pp. 114-119
    • Gallucci, S.1    Matzinger, P.2
  • 23
    • 1642617628 scopus 로고    scopus 로고
    • The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4
    • Hsu L.C., Park J.M., Zhang K., et al. The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4. Nature 428 6980 (2004) 341-345
    • (2004) Nature , vol.428 , Issue.6980 , pp. 341-345
    • Hsu, L.C.1    Park, J.M.2    Zhang, K.3
  • 24
    • 33644592813 scopus 로고    scopus 로고
    • Lipoteichoic acid (LTA) from Staphylococcus aureus stimulates human neutrophil cytokine release by a CD14-dependent, Toll-like-receptor-independent mechanism: autocrine role of tumor necrosis factor-[alpha] in mediating LTA-induced interleukin-8 generation
    • Hattar K., Grandel U., Moeller A., et al. Lipoteichoic acid (LTA) from Staphylococcus aureus stimulates human neutrophil cytokine release by a CD14-dependent, Toll-like-receptor-independent mechanism: autocrine role of tumor necrosis factor-[alpha] in mediating LTA-induced interleukin-8 generation. Crit Care Med 34 3 (2006) 835-841
    • (2006) Crit Care Med , vol.34 , Issue.3 , pp. 835-841
    • Hattar, K.1    Grandel, U.2    Moeller, A.3
  • 25
    • 33750004226 scopus 로고    scopus 로고
    • Herpes virus entry mediator synergizes with Toll-like receptor mediated neutrophil inflammatory responses
    • Haselmayer P., Tenzer S., Kwon B.S., et al. Herpes virus entry mediator synergizes with Toll-like receptor mediated neutrophil inflammatory responses. Immunology 119 3 (2006) 404-411
    • (2006) Immunology , vol.119 , Issue.3 , pp. 404-411
    • Haselmayer, P.1    Tenzer, S.2    Kwon, B.S.3
  • 26
    • 27844541797 scopus 로고    scopus 로고
    • Control of B-cell responses by Toll-like receptors
    • Pasare C., and Medzhitov R. Control of B-cell responses by Toll-like receptors. Nature 438 7066 (2005) 364-368
    • (2005) Nature , vol.438 , Issue.7066 , pp. 364-368
    • Pasare, C.1    Medzhitov, R.2
  • 27
    • 33645956556 scopus 로고    scopus 로고
    • Toll-like receptor stimulation as a third signal required for activation of human naive B cells
    • Ruprecht C.R., and Lanzavecchia A. Toll-like receptor stimulation as a third signal required for activation of human naive B cells. Eur J Immunol 36 4 (2006) 810-816
    • (2006) Eur J Immunol , vol.36 , Issue.4 , pp. 810-816
    • Ruprecht, C.R.1    Lanzavecchia, A.2
  • 28
    • 23944509107 scopus 로고    scopus 로고
    • Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function
    • Peng G., Guo Z., Kiniwa Y., et al. Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science 309 5739 (2005) 1380-1384
    • (2005) Science , vol.309 , Issue.5739 , pp. 1380-1384
    • Peng, G.1    Guo, Z.2    Kiniwa, Y.3
  • 29
    • 29644431589 scopus 로고    scopus 로고
    • Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells
    • Chaperot L., Blum A., Manches O., et al. Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells. J Immunol 176 1 (2006) 248-255
    • (2006) J Immunol , vol.176 , Issue.1 , pp. 248-255
    • Chaperot, L.1    Blum, A.2    Manches, O.3
  • 30
    • 0037153130 scopus 로고    scopus 로고
    • The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
    • Horng T., Barton G.M., Flavell R.A., et al. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 420 6913 (2002) 329-333
    • (2002) Nature , vol.420 , Issue.6913 , pp. 329-333
    • Horng, T.1    Barton, G.M.2    Flavell, R.A.3
  • 31
    • 30544451546 scopus 로고    scopus 로고
    • Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
    • Hacker H., Redecke V., Blagoev B., et al. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 439 7073 (2006) 204-207
    • (2006) Nature , vol.439 , Issue.7073 , pp. 204-207
    • Hacker, H.1    Redecke, V.2    Blagoev, B.3
  • 32
    • 33744720397 scopus 로고    scopus 로고
    • Sequence variants in toll-like receptor 10 are associated with nasopharyngeal carcinoma risk
    • Zhou X.-X., Jia W.-H., Shen G.-P., et al. Sequence variants in toll-like receptor 10 are associated with nasopharyngeal carcinoma risk. Cancer Epidemiol Biomarkers Prev 15 5 (2006) 862-866
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , Issue.5 , pp. 862-866
    • Zhou, X.-X.1    Jia, W.-H.2    Shen, G.-P.3
  • 33
    • 20144389424 scopus 로고    scopus 로고
    • Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes
    • Kollisch G., Kalali B.N., Voelcker V., et al. Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes. Immunology 114 4 (2005) 531-541
    • (2005) Immunology , vol.114 , Issue.4 , pp. 531-541
    • Kollisch, G.1    Kalali, B.N.2    Voelcker, V.3
  • 34
    • 11844289006 scopus 로고    scopus 로고
    • Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly (I:C)
    • Schaefer T.M., Fahey J.V., Wright J.A., et al. Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly (I:C). J Immunol 174 2 (2005) 992-1002
    • (2005) J Immunol , vol.174 , Issue.2 , pp. 992-1002
    • Schaefer, T.M.1    Fahey, J.V.2    Wright, J.A.3
  • 35
    • 20344364201 scopus 로고    scopus 로고
    • Genetic analysis of innate immunity: identification and function of the TIR adapter proteins
    • Beutler B., Hoebe K., Georgel P., et al. Genetic analysis of innate immunity: identification and function of the TIR adapter proteins. Adv Exp Med Biol 560 (2005) 29-39
    • (2005) Adv Exp Med Biol , vol.560 , pp. 29-39
    • Beutler, B.1    Hoebe, K.2    Georgel, P.3
  • 36
    • 4344627821 scopus 로고    scopus 로고
    • Endogenous ligands of Toll-like receptors
    • Tsan M.F., and Gao B. Endogenous ligands of Toll-like receptors. J Leukoc Biol 76 3 (2004) 514-519
    • (2004) J Leukoc Biol , vol.76 , Issue.3 , pp. 514-519
    • Tsan, M.F.1    Gao, B.2
  • 37
    • 33750470437 scopus 로고    scopus 로고
    • The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity
    • Lauzon N.M., Mian F., MacKenzie R., et al. The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity. Cell Immunol 241 2 (2006) 102-112
    • (2006) Cell Immunol , vol.241 , Issue.2 , pp. 102-112
    • Lauzon, N.M.1    Mian, F.2    MacKenzie, R.3
  • 38
    • 3042711969 scopus 로고    scopus 로고
    • CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells
    • Sivori S., Falco M., Della Chiesa M., et al. CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells. Proc Natl Acad Sci USA 101 27 (2004) 10116-10121
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.27 , pp. 10116-10121
    • Sivori, S.1    Falco, M.2    Della Chiesa, M.3
  • 39
    • 33749355639 scopus 로고    scopus 로고
    • TLR agonists promote ERK-mediated preferential IL-10 production of regulatory dendritic cells (diffDCs), leading to NK-cell activation
    • Qian C., Jiang X., An H., et al. TLR agonists promote ERK-mediated preferential IL-10 production of regulatory dendritic cells (diffDCs), leading to NK-cell activation. Blood 108 7 (2006) 2307-2315
    • (2006) Blood , vol.108 , Issue.7 , pp. 2307-2315
    • Qian, C.1    Jiang, X.2    An, H.3
  • 40
    • 27744451943 scopus 로고    scopus 로고
    • MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo
    • Delale T., Paquin A., Asselin-Paturel C., et al. MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo. J Immunol 175 10 (2005) 6723-6732
    • (2005) J Immunol , vol.175 , Issue.10 , pp. 6723-6732
    • Delale, T.1    Paquin, A.2    Asselin-Paturel, C.3
  • 41
    • 0016836061 scopus 로고
    • Intralesional BCG, intravenous immune lymphocytes, and immunization with neuraminidase-treated tumor cells to manage melanoma; a clinical assessment
    • Seigler H.F., Shingleton W.W., and Pickrell K.L. Intralesional BCG, intravenous immune lymphocytes, and immunization with neuraminidase-treated tumor cells to manage melanoma; a clinical assessment. Plast Reconstr Surg 55 3 (1975) 294-298
    • (1975) Plast Reconstr Surg , vol.55 , Issue.3 , pp. 294-298
    • Seigler, H.F.1    Shingleton, W.W.2    Pickrell, K.L.3
  • 42
    • 0016776479 scopus 로고
    • Regression of pulmonary metastatic disease associated with intralesional BCG therapy of intracutaneous melanoma metastases
    • Mastrangelo M.J., Bellet R.E., Berkelhammer J., et al. Regression of pulmonary metastatic disease associated with intralesional BCG therapy of intracutaneous melanoma metastases. Cancer 36 4 (1975) 1305-1308
    • (1975) Cancer , vol.36 , Issue.4 , pp. 1305-1308
    • Mastrangelo, M.J.1    Bellet, R.E.2    Berkelhammer, J.3
  • 43
    • 0015929865 scopus 로고
    • BCG in malignant melanoma
    • Baker M.A., and Taub R.N. BCG in malignant melanoma. Lancet 1 7812 (1973) 1117-1118
    • (1973) Lancet , vol.1 , Issue.7812 , pp. 1117-1118
    • Baker, M.A.1    Taub, R.N.2
  • 44
    • 0015405582 scopus 로고
    • Regression of intradermal malignant melanoma after intralesional injection of Mycobacterium bovis strain BCG
    • Nathanson L. Regression of intradermal malignant melanoma after intralesional injection of Mycobacterium bovis strain BCG. Cancer Chemother Reports - Part 1 56 5 (1972) 659-665
    • (1972) Cancer Chemother Reports - Part 1 , vol.56 , Issue.5 , pp. 659-665
    • Nathanson, L.1
  • 45
    • 0015306784 scopus 로고
    • Immunological effects of BCG in malignant melanoma: two modes of administration compared
    • Bluming A.Z., Vogel C.L., Ziegler J.L., et al. Immunological effects of BCG in malignant melanoma: two modes of administration compared. Ann Intern Med 76 3 (1972) 405-411
    • (1972) Ann Intern Med , vol.76 , Issue.3 , pp. 405-411
    • Bluming, A.Z.1    Vogel, C.L.2    Ziegler, J.L.3
  • 46
    • 0017276806 scopus 로고
    • Intralesional BCG in the treatment of metastatic malignant melanoma
    • Mastrangelo M.J., Sulit H.L., Prehn L.M., et al. Intralesional BCG in the treatment of metastatic malignant melanoma. Cancer 37 2 (1976) 684-692
    • (1976) Cancer , vol.37 , Issue.2 , pp. 684-692
    • Mastrangelo, M.J.1    Sulit, H.L.2    Prehn, L.M.3
  • 47
    • 0020260646 scopus 로고
    • Intralymphatic and regional surgical adjuvant immunotherapy in high-risk melanoma of the extremities
    • Ariyan S., Kirkwood J.M., Mitchell M.S., et al. Intralymphatic and regional surgical adjuvant immunotherapy in high-risk melanoma of the extremities. Surgery 92 3 (1982) 459-463
    • (1982) Surgery , vol.92 , Issue.3 , pp. 459-463
    • Ariyan, S.1    Kirkwood, J.M.2    Mitchell, M.S.3
  • 48
    • 0028989972 scopus 로고
    • Approaches to augmenting the immunogenicity of melanoma gangliosides: from whole melanoma cells to ganglioside-KLH conjugate vaccines
    • Livingston P.O. Approaches to augmenting the immunogenicity of melanoma gangliosides: from whole melanoma cells to ganglioside-KLH conjugate vaccines. Immunol Rev 145 (1995) 147-166
    • (1995) Immunol Rev , vol.145 , pp. 147-166
    • Livingston, P.O.1
  • 49
    • 19944383121 scopus 로고    scopus 로고
    • Prior immunisation of patients with malignant melanoma with vaccinia or BCG is associated with better survival. A European Organization for Research and Treatment of Cancer cohort study on 542 patients
    • Kolmel K.F., Grange J.M., Krone B., et al. Prior immunisation of patients with malignant melanoma with vaccinia or BCG is associated with better survival. A European Organization for Research and Treatment of Cancer cohort study on 542 patients. Eur J Cancer 41 1 (2005) 118-125
    • (2005) Eur J Cancer , vol.41 , Issue.1 , pp. 118-125
    • Kolmel, K.F.1    Grange, J.M.2    Krone, B.3
  • 50
    • 1842582038 scopus 로고    scopus 로고
    • Mature results of a phase III randomized trial of bacillus Calmette-Guerin (BCG) versus observation and BCG plus dacarbazine versus BCG in the adjuvant therapy of American Joint Committee on Cancer stage I-III melanoma (E1673): a trial of the Eastern Oncology Group
    • Agarwala S.S., Neuberg D., Park Y., et al. Mature results of a phase III randomized trial of bacillus Calmette-Guerin (BCG) versus observation and BCG plus dacarbazine versus BCG in the adjuvant therapy of American Joint Committee on Cancer stage I-III melanoma (E1673): a trial of the Eastern Oncology Group. Cancer 100 8 (2004) 1692-1698
    • (2004) Cancer , vol.100 , Issue.8 , pp. 1692-1698
    • Agarwala, S.S.1    Neuberg, D.2    Park, Y.3
  • 51
    • 0034777579 scopus 로고    scopus 로고
    • Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12
    • Krug A., Towarowski A., Britsch S., et al. Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12. Eur J Immunol 31 10 (2001) 3026-3037
    • (2001) Eur J Immunol , vol.31 , Issue.10 , pp. 3026-3037
    • Krug, A.1    Towarowski, A.2    Britsch, S.3
  • 52
    • 0141926517 scopus 로고    scopus 로고
    • Aerosolized granulocyte macrophage colony-stimulating factor (GM-CSF) therapy in metastatic cancer
    • Rao R.D., Anderson P.M., Arndt C.A., et al. Aerosolized granulocyte macrophage colony-stimulating factor (GM-CSF) therapy in metastatic cancer. Am J Clin Oncol 26 5 (2003) 493-498
    • (2003) Am J Clin Oncol , vol.26 , Issue.5 , pp. 493-498
    • Rao, R.D.1    Anderson, P.M.2    Arndt, C.A.3
  • 53
    • 11344249225 scopus 로고    scopus 로고
    • Quantitative analysis of melanoma-induced cytokine-mediated immunosuppression in melanoma sentinel nodes
    • Lee J.H., Torisu-Itakara H., Cochran A.J., et al. Quantitative analysis of melanoma-induced cytokine-mediated immunosuppression in melanoma sentinel nodes. Clin Cancer Res 11 1 (2005) 107-112
    • (2005) Clin Cancer Res , vol.11 , Issue.1 , pp. 107-112
    • Lee, J.H.1    Torisu-Itakara, H.2    Cochran, A.J.3
  • 54
    • 0032886907 scopus 로고    scopus 로고
    • Intradermal injection of granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with metastatic melanoma recruits dendritic cells
    • Nasi M.L., Lieberman P., Busam K.J., et al. Intradermal injection of granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with metastatic melanoma recruits dendritic cells. Cytokines Cell Mol Ther 5 3 (1999) 139-144
    • (1999) Cytokines Cell Mol Ther , vol.5 , Issue.3 , pp. 139-144
    • Nasi, M.L.1    Lieberman, P.2    Busam, K.J.3
  • 55
    • 0029949031 scopus 로고    scopus 로고
    • Clinical responses and lymphoid infiltrates in metastatic melanoma following treatment with intralesional GM-CSF
    • Si Z., Hersey P., and Coates A.S. Clinical responses and lymphoid infiltrates in metastatic melanoma following treatment with intralesional GM-CSF. Melanoma Res 6 3 (1996) 247-255
    • (1996) Melanoma Res , vol.6 , Issue.3 , pp. 247-255
    • Si, Z.1    Hersey, P.2    Coates, A.S.3
  • 56
    • 0033024863 scopus 로고    scopus 로고
    • High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993
    • Atkins M.B., Lotze M.T., Dutcher J.P., et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol 17 7 (1999) 2105-2116
    • (1999) J Clin Oncol , vol.17 , Issue.7 , pp. 2105-2116
    • Atkins, M.B.1    Lotze, M.T.2    Dutcher, J.P.3
  • 57
    • 29444456949 scopus 로고    scopus 로고
    • Interleukin-2 for the treatment of melanoma
    • Tarhini A.A., and Agarwala S.S. Interleukin-2 for the treatment of melanoma. Curr Opin Investig Drugs 6 12 (2005) 1234-1239
    • (2005) Curr Opin Investig Drugs , vol.6 , Issue.12 , pp. 1234-1239
    • Tarhini, A.A.1    Agarwala, S.S.2
  • 58
    • 0028266553 scopus 로고
    • Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2
    • Rosenberg S.A., Yang J.C., Topalian S.L., et al. Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2. JAMA 271 12 (1994) 907-913
    • (1994) JAMA , vol.271 , Issue.12 , pp. 907-913
    • Rosenberg, S.A.1    Yang, J.C.2    Topalian, S.L.3
  • 59
    • 0033848628 scopus 로고    scopus 로고
    • High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update
    • Atkins M.B., Kunkel L., Sznol M., et al. High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J Sci Am 6 Suppl 1 (2000) S11-S14
    • (2000) Cancer J Sci Am , vol.6 , Issue.SUPPL. 1
    • Atkins, M.B.1    Kunkel, L.2    Sznol, M.3
  • 60
    • 0030008301 scopus 로고    scopus 로고
    • Vitiligo in patients with melanoma: normal tissue antigens can be targets for cancer immunotherapy
    • Rosenberg S.A., and White D.E. Vitiligo in patients with melanoma: normal tissue antigens can be targets for cancer immunotherapy. J Immunother Emphasis Tumor Immunol 19 1 (1996) 81-84
    • (1996) J Immunother Emphasis Tumor Immunol , vol.19 , Issue.1 , pp. 81-84
    • Rosenberg, S.A.1    White, D.E.2
  • 61
    • 0038153907 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
    • Phan G.Q., Yang J.C., Sherry R.M., et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci USA 100 14 (2003) 8372-8377
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.14 , pp. 8372-8377
    • Phan, G.Q.1    Yang, J.C.2    Sherry, R.M.3
  • 62
    • 28844432420 scopus 로고    scopus 로고
    • Technology evaluation: ipilimumab, Medarex/Bristol-Myers Squibb
    • Morse M.A. Technology evaluation: ipilimumab, Medarex/Bristol-Myers Squibb. Curr Opin Mol Ther 7 6 (2005) 588-597
    • (2005) Curr Opin Mol Ther , vol.7 , Issue.6 , pp. 588-597
    • Morse, M.A.1
  • 63
    • 32644467549 scopus 로고    scopus 로고
    • Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
    • Ribas A., Camacho L.H., Lopez-Berestein G., et al. Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. J Clin Oncol 23 35 (2005) 8968-8977
    • (2005) J Clin Oncol , vol.23 , Issue.35 , pp. 8968-8977
    • Ribas, A.1    Camacho, L.H.2    Lopez-Berestein, G.3
  • 64
    • 0032526030 scopus 로고    scopus 로고
    • Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons
    • Pfeffer L.M., Dinarello C.A., Herberman R.B., et al. Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons. Cancer Res 58 12 (1998) 2489-2499
    • (1998) Cancer Res , vol.58 , Issue.12 , pp. 2489-2499
    • Pfeffer, L.M.1    Dinarello, C.A.2    Herberman, R.B.3
  • 65
    • 33750321707 scopus 로고    scopus 로고
    • Interferons, immunity and cancer immunoediting
    • Dunn G.P., Koebel C.M., and Schreiber R.D. Interferons, immunity and cancer immunoediting. Nat Rev Immunol 6 11 (2006) 836-848
    • (2006) Nat Rev Immunol , vol.6 , Issue.11 , pp. 836-848
    • Dunn, G.P.1    Koebel, C.M.2    Schreiber, R.D.3
  • 66
    • 0742306127 scopus 로고    scopus 로고
    • Immunotherapy of surgical malignancies
    • Morse M.A., Lyerly H.K., Clay T.M., et al. Immunotherapy of surgical malignancies. Curr Probl Surg 41 1 (2004) 15-132
    • (2004) Curr Probl Surg , vol.41 , Issue.1 , pp. 15-132
    • Morse, M.A.1    Lyerly, H.K.2    Clay, T.M.3
  • 67
    • 0030030347 scopus 로고    scopus 로고
    • Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group trial EST 1684
    • Kirkwood J.M., Strawderman M.H., Ernstoff M.S., et al. Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group trial EST 1684. J Clin Oncol 14 1 (1996) 7-17
    • (1996) J Clin Oncol , vol.14 , Issue.1 , pp. 7-17
    • Kirkwood, J.M.1    Strawderman, M.H.2    Ernstoff, M.S.3
  • 68
    • 0034088027 scopus 로고    scopus 로고
    • High- and low-dose interferon alfa-2b in high-risk melanoma: first analysis of intergroup trial E1690/S9111/C9190
    • Kirkwood J.M., Ibrahim J.G., Sondak V.K., et al. High- and low-dose interferon alfa-2b in high-risk melanoma: first analysis of intergroup trial E1690/S9111/C9190. J Clin Oncol 18 12 (2000) 2444-2458
    • (2000) J Clin Oncol , vol.18 , Issue.12 , pp. 2444-2458
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sondak, V.K.3
  • 69
    • 0035339880 scopus 로고    scopus 로고
    • High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801
    • Kirkwood J.M., Ibrahim J.G., Sosman J.A., et al. High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. J Clin Oncol 19 9 (2001) 2370-2380
    • (2001) J Clin Oncol , vol.19 , Issue.9 , pp. 2370-2380
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sosman, J.A.3
  • 70
    • 0035281923 scopus 로고    scopus 로고
    • High-dose interferon alfa-2b does not diminish antibody response to GM2 vaccination in patients with resected melanoma: results of the multicenter Eastern Cooperative Oncology Group phase II trial E2696
    • Kirkwood J.M., Ibrahim J., Lawson D.H., et al. High-dose interferon alfa-2b does not diminish antibody response to GM2 vaccination in patients with resected melanoma: results of the multicenter Eastern Cooperative Oncology Group phase II trial E2696. J Clin Oncol 19 5 (2001) 1430-1436
    • (2001) J Clin Oncol , vol.19 , Issue.5 , pp. 1430-1436
    • Kirkwood, J.M.1    Ibrahim, J.2    Lawson, D.H.3
  • 71
    • 0034784384 scopus 로고    scopus 로고
    • The Sunbelt Melanoma Trial
    • McMasters K.M. The Sunbelt Melanoma Trial. Ann Surg Oncol 8 9 Suppl (2001) 41S-43S
    • (2001) Ann Surg Oncol , vol.8 , Issue.9 SUPPL
    • McMasters, K.M.1
  • 72
    • 3042776109 scopus 로고    scopus 로고
    • Lessons learned from the Sunbelt Melanoma Trial
    • McMasters K.M., Noyes R.D., Reintgen D.S., et al. Lessons learned from the Sunbelt Melanoma Trial. J Surg Oncol 86 4 (2004) 212-223
    • (2004) J Surg Oncol , vol.86 , Issue.4 , pp. 212-223
    • McMasters, K.M.1    Noyes, R.D.2    Reintgen, D.S.3
  • 73
    • 33745548124 scopus 로고    scopus 로고
    • Prospective multi-institutional study of reverse transcriptase polymerase chain reaction for molecular staging of melanoma
    • Scoggins C.R., Ross M.I., Reintgen D.S., et al. Prospective multi-institutional study of reverse transcriptase polymerase chain reaction for molecular staging of melanoma. J Clin Oncol 24 18 (2006) 2849-2857
    • (2006) J Clin Oncol , vol.24 , Issue.18 , pp. 2849-2857
    • Scoggins, C.R.1    Ross, M.I.2    Reintgen, D.S.3
  • 74
    • 3242734089 scopus 로고    scopus 로고
    • Tolerability of adjuvant high-dose interferon alfa-2b: 1 month versus 1 year-a Hellenic Cooperative Oncology Group study
    • Gogas H., Bafaloukos D., Ioannovich J., et al. Tolerability of adjuvant high-dose interferon alfa-2b: 1 month versus 1 year-a Hellenic Cooperative Oncology Group study. Anticancer Res 24 3b (2004) 1947-1952
    • (2004) Anticancer Res , vol.24 , Issue.3 b , pp. 1947-1952
    • Gogas, H.1    Bafaloukos, D.2    Ioannovich, J.3
  • 75
    • 0037235099 scopus 로고    scopus 로고
    • TNF-alpha downregulates vascular endothelial Flk-1 expression in human melanoma xenograft model
    • Menon C., Iyer M., Prabakaran I., et al. TNF-alpha downregulates vascular endothelial Flk-1 expression in human melanoma xenograft model. Am J Physiol Heart Circ Physiol 284 1 (2003) H317-H329
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , Issue.1
    • Menon, C.1    Iyer, M.2    Prabakaran, I.3
  • 76
    • 33748662393 scopus 로고    scopus 로고
    • Randomized multicenter trial of hyperthermic isolated limb perfusion with melphalan alone compared with melphalan plus tumor necrosis factor: American College of Surgeons Oncology Group trial Z0020
    • Cornett W.R., McCall L.M., Petersen R.P., et al. Randomized multicenter trial of hyperthermic isolated limb perfusion with melphalan alone compared with melphalan plus tumor necrosis factor: American College of Surgeons Oncology Group trial Z0020. J Clin Oncol 24 25 (2006) 4196-4201
    • (2006) J Clin Oncol , vol.24 , Issue.25 , pp. 4196-4201
    • Cornett, W.R.1    McCall, L.M.2    Petersen, R.P.3
  • 77
    • 33845629436 scopus 로고    scopus 로고
    • Isolated limb perfusion with melphalan and tumor necrosis factor alpha for advanced melanoma and soft-tissue sarcoma
    • Hayes A.J., Neuhaus S.J., Clark M.A., et al. Isolated limb perfusion with melphalan and tumor necrosis factor alpha for advanced melanoma and soft-tissue sarcoma. Ann Surg Oncol 14 1 (2007) 230-238
    • (2007) Ann Surg Oncol , vol.14 , Issue.1 , pp. 230-238
    • Hayes, A.J.1    Neuhaus, S.J.2    Clark, M.A.3
  • 78
    • 33746052513 scopus 로고    scopus 로고
    • Isolated limb perfusion for melanoma patients-a review of its indications and the role of tumour necrosis factor-alpha
    • Grunhagen D.J., de Wilt J.H., van Geel A.N., et al. Isolated limb perfusion for melanoma patients-a review of its indications and the role of tumour necrosis factor-alpha. Eur J Surg Oncol 32 4 (2006) 371-380
    • (2006) Eur J Surg Oncol , vol.32 , Issue.4 , pp. 371-380
    • Grunhagen, D.J.1    de Wilt, J.H.2    van Geel, A.N.3
  • 79
    • 23744455028 scopus 로고    scopus 로고
    • Efficacy of repeat isolated limb perfusions with tumor necrosis factor alpha and melphalan for multiple in-transit metastases in patients with prior isolated limb perfusion failure
    • Grunhagen D.J., van Etten B., Brunstein F., et al. Efficacy of repeat isolated limb perfusions with tumor necrosis factor alpha and melphalan for multiple in-transit metastases in patients with prior isolated limb perfusion failure. Ann Surg Oncol 12 8 (2005) 609-615
    • (2005) Ann Surg Oncol , vol.12 , Issue.8 , pp. 609-615
    • Grunhagen, D.J.1    van Etten, B.2    Brunstein, F.3
  • 80
    • 2342544826 scopus 로고    scopus 로고
    • Hyperthermic isolated limb perfusion with low-dose tumor necrosis factor-alpha and melphalan for bulky in-transit melanoma metastases
    • Rossi C.R., Foletto M., Mocellin S., et al. Hyperthermic isolated limb perfusion with low-dose tumor necrosis factor-alpha and melphalan for bulky in-transit melanoma metastases. Ann Surg Oncol 11 2 (2004) 173-177
    • (2004) Ann Surg Oncol , vol.11 , Issue.2 , pp. 173-177
    • Rossi, C.R.1    Foletto, M.2    Mocellin, S.3
  • 81
    • 0031929620 scopus 로고    scopus 로고
    • Pilot study of subcutaneous recombinant human interleukin 12 in metastatic melanoma
    • Bajetta E., Del Vecchio M., Mortarini R., et al. Pilot study of subcutaneous recombinant human interleukin 12 in metastatic melanoma. Clin Cancer Res 4 1 (1998) 75-85
    • (1998) Clin Cancer Res , vol.4 , Issue.1 , pp. 75-85
    • Bajetta, E.1    Del Vecchio, M.2    Mortarini, R.3
  • 82
    • 0038690512 scopus 로고    scopus 로고
    • Phase I trial of concurrent twice-weekly recombinant human interleukin-12 plus low-dose IL-2 in patients with melanoma or renal cell carcinoma
    • Gollob J.A., Veenstra K.G., Parker R.A., et al. Phase I trial of concurrent twice-weekly recombinant human interleukin-12 plus low-dose IL-2 in patients with melanoma or renal cell carcinoma. J Clin Oncol 21 13 (2003) 2564-2573
    • (2003) J Clin Oncol , vol.21 , Issue.13 , pp. 2564-2573
    • Gollob, J.A.1    Veenstra, K.G.2    Parker, R.A.3
  • 83
    • 4344684281 scopus 로고    scopus 로고
    • Clinical and immunologic effects of subcutaneously administered interleukin-12 and interferon alfa-2b: phase I trial of patients with metastatic renal cell carcinoma or malignant melanoma
    • Alatrash G., Hutson T.E., Molto L., et al. Clinical and immunologic effects of subcutaneously administered interleukin-12 and interferon alfa-2b: phase I trial of patients with metastatic renal cell carcinoma or malignant melanoma. J Clin Oncol 22 14 (2004) 2891-2900
    • (2004) J Clin Oncol , vol.22 , Issue.14 , pp. 2891-2900
    • Alatrash, G.1    Hutson, T.E.2    Molto, L.3
  • 84
    • 0035884621 scopus 로고    scopus 로고
    • Effects of interleukin-12 on the immune response to a multipeptide vaccine for resected metastatic melanoma
    • Lee P., Wang F., Kuniyoshi J., et al. Effects of interleukin-12 on the immune response to a multipeptide vaccine for resected metastatic melanoma. J Clin Oncol 19 18 (2001) 3836-3847
    • (2001) J Clin Oncol , vol.19 , Issue.18 , pp. 3836-3847
    • Lee, P.1    Wang, F.2    Kuniyoshi, J.3
  • 85
    • 10844248144 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor and interleukin-2 fusion cDNA for cancer gene immunotherapy
    • Stagg J., Wu J.H., Bouganim N., et al. Granulocyte-macrophage colony-stimulating factor and interleukin-2 fusion cDNA for cancer gene immunotherapy. Cancer Res 64 24 (2004) 8795-8799
    • (2004) Cancer Res , vol.64 , Issue.24 , pp. 8795-8799
    • Stagg, J.1    Wu, J.H.2    Bouganim, N.3
  • 86
  • 87
    • 5144228905 scopus 로고    scopus 로고
    • In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer
    • Nagai H., Horikawa T., Hara I., et al. In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer. Exp Dermatol 13 10 (2004) 613-620
    • (2004) Exp Dermatol , vol.13 , Issue.10 , pp. 613-620
    • Nagai, H.1    Horikawa, T.2    Hara, I.3
  • 88
    • 4644342928 scopus 로고    scopus 로고
    • Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells
    • Turk M.J., Guevara-Patino J.A., Rizzuto G.A., et al. Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J Exp Med 200 6 (2004) 771-782
    • (2004) J Exp Med , vol.200 , Issue.6 , pp. 771-782
    • Turk, M.J.1    Guevara-Patino, J.A.2    Rizzuto, G.A.3
  • 89
    • 3242736641 scopus 로고    scopus 로고
    • Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice
    • Jones E., Dahm-Vicker M., Simon A.K., et al. Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice. Cancer Immunity 2 (2002) 1-12
    • (2002) Cancer Immunity , vol.2 , pp. 1-12
    • Jones, E.1    Dahm-Vicker, M.2    Simon, A.K.3
  • 90
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller R.P., van Duivenvoorde L.M., van Elsas A., et al. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 194 6 (2001) 823-832
    • (2001) J Exp Med , vol.194 , Issue.6 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3
  • 91
    • 33846471662 scopus 로고    scopus 로고
    • Denileukin diftitox: a biotherapeutic paradigm shift in the treatment of lymphoid-derived disorders
    • Turturro F. Denileukin diftitox: a biotherapeutic paradigm shift in the treatment of lymphoid-derived disorders. Expert Rev Anticancer Ther 7 1 (2007) 11-17
    • (2007) Expert Rev Anticancer Ther , vol.7 , Issue.1 , pp. 11-17
    • Turturro, F.1
  • 92
    • 33644544666 scopus 로고    scopus 로고
    • Clinical experience with denileukin diftitox (ONTAK)
    • Foss F. Clinical experience with denileukin diftitox (ONTAK). Semin Oncol 33 1 Suppl 3 (2006) S11-S16
    • (2006) Semin Oncol , vol.33 , Issue.1 SUPPL. 3
    • Foss, F.1
  • 93
    • 27444435581 scopus 로고    scopus 로고
    • Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma
    • Attia P., Maker A.V., Haworth L.R., et al. Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma. J Immunother 28 6 (2005) 582-592
    • (2005) J Immunother , vol.28 , Issue.6 , pp. 582-592
    • Attia, P.1    Maker, A.V.2    Haworth, L.R.3
  • 94
    • 0036079798 scopus 로고    scopus 로고
    • Technology evaluation: Allovectin-7, Vical
    • Galanis E. Technology evaluation: Allovectin-7, Vical. Curr Opin Mol Ther 4 1 (2002) 80-87
    • (2002) Curr Opin Mol Ther , vol.4 , Issue.1 , pp. 80-87
    • Galanis, E.1
  • 95
    • 33646252963 scopus 로고    scopus 로고
    • Cytokine-based therapy and biochemotherapy for advanced melanoma
    • Atkins M.B. Cytokine-based therapy and biochemotherapy for advanced melanoma. Clin Cancer Res 12 7 Pt 2 (2006) 2353s-2358s
    • (2006) Clin Cancer Res , vol.12 , Issue.7 PART 2
    • Atkins, M.B.1
  • 96
    • 33749033674 scopus 로고    scopus 로고
    • Biochemotherapy of melanoma
    • [quiz 189]
    • Keilholz U. Biochemotherapy of melanoma. Forum (Genova) 13 2 (2003) 158-165 [quiz 189]
    • (2003) Forum (Genova) , vol.13 , Issue.2 , pp. 158-165
    • Keilholz, U.1
  • 97
    • 22344434804 scopus 로고    scopus 로고
    • Metastatic melanoma: is biochemotherapy the future?
    • Alexandrescu D.T., Dutcher J.P., and Wiernik P.H. Metastatic melanoma: is biochemotherapy the future?. Med Oncol 22 2 (2005) 101-111
    • (2005) Med Oncol , vol.22 , Issue.2 , pp. 101-111
    • Alexandrescu, D.T.1    Dutcher, J.P.2    Wiernik, P.H.3
  • 98
    • 0036794923 scopus 로고    scopus 로고
    • Biochemotherapy for advanced melanoma
    • Buzaid A.C. Biochemotherapy for advanced melanoma. Crit Rev Oncol Hematol 44 1 (2002) 103-108
    • (2002) Crit Rev Oncol Hematol , vol.44 , Issue.1 , pp. 103-108
    • Buzaid, A.C.1
  • 99
    • 0036199834 scopus 로고    scopus 로고
    • Metastatic melanoma: chemotherapy to biochemotherapy
    • O'Day S.J., Kim C.J., and Reintgen D.S. Metastatic melanoma: chemotherapy to biochemotherapy. Cancer Control 9 1 (2002) 31-38
    • (2002) Cancer Control , vol.9 , Issue.1 , pp. 31-38
    • O'Day, S.J.1    Kim, C.J.2    Reintgen, D.S.3
  • 100
    • 33750078441 scopus 로고    scopus 로고
    • Long-term survival in metastatic melanoma patients treated with sequential biochemotherapy: report of a phase II study
    • Neri B., Vannozzi L., Fulignati C., et al. Long-term survival in metastatic melanoma patients treated with sequential biochemotherapy: report of a phase II study. Cancer Invest 24 5 (2006) 474-478
    • (2006) Cancer Invest , vol.24 , Issue.5 , pp. 474-478
    • Neri, B.1    Vannozzi, L.2    Fulignati, C.3
  • 101
    • 33745972933 scopus 로고    scopus 로고
    • Phase II multicenter study of neoadjuvant biochemotherapy for patients with stage III malignant melanoma
    • Lewis K.D., Robinson W.A., McCarter M., et al. Phase II multicenter study of neoadjuvant biochemotherapy for patients with stage III malignant melanoma. J Clin Oncol 24 19 (2006) 3157-3163
    • (2006) J Clin Oncol , vol.24 , Issue.19 , pp. 3157-3163
    • Lewis, K.D.1    Robinson, W.A.2    McCarter, M.3
  • 102
    • 33645454090 scopus 로고    scopus 로고
    • A biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, temozolomide (Temodal), interferon-alfa and interleukin-2 for metastatic melanoma: a phase II study
    • Ron I.G., Sarid D., Ryvo L., et al. A biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, temozolomide (Temodal), interferon-alfa and interleukin-2 for metastatic melanoma: a phase II study. Melanoma Res 16 1 (2006) 65-69
    • (2006) Melanoma Res , vol.16 , Issue.1 , pp. 65-69
    • Ron, I.G.1    Sarid, D.2    Ryvo, L.3
  • 104
    • 0029061079 scopus 로고
    • Response of subcutaneous and cutaneous metastases of malignant melanoma to combined cytostatic plus interferon therapy
    • Hahka-Kemppinen M., Muhonen T., Virolainen M., et al. Response of subcutaneous and cutaneous metastases of malignant melanoma to combined cytostatic plus interferon therapy. Br J Dermatol 132 6 (1995) 973-977
    • (1995) Br J Dermatol , vol.132 , Issue.6 , pp. 973-977
    • Hahka-Kemppinen, M.1    Muhonen, T.2    Virolainen, M.3
  • 105
    • 0028918831 scopus 로고
    • Intermittent interferon and polychemotherapy in metastatic melanoma
    • Vuoristo M.S., Grohn P., Kellokumpu-Lehtinen P., et al. Intermittent interferon and polychemotherapy in metastatic melanoma. J Cancer Res Clin Oncol 121 3 (1995) 175-180
    • (1995) J Cancer Res Clin Oncol , vol.121 , Issue.3 , pp. 175-180
    • Vuoristo, M.S.1    Grohn, P.2    Kellokumpu-Lehtinen, P.3
  • 106
    • 0037089629 scopus 로고    scopus 로고
    • Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a phase III randomized trial
    • Eton O., Legha S.S., Bedikian A.Y., et al. Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a phase III randomized trial. J Clin Oncol 20 8 (2002) 2045-2052
    • (2002) J Clin Oncol , vol.20 , Issue.8 , pp. 2045-2052
    • Eton, O.1    Legha, S.S.2    Bedikian, A.Y.3
  • 107
    • 24744458382 scopus 로고    scopus 로고
    • A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF
    • Lewis K.D., Gibbs P., O'Day S., et al. A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF. Cancer Invest 23 4 (2005) 303-308
    • (2005) Cancer Invest , vol.23 , Issue.4 , pp. 303-308
    • Lewis, K.D.1    Gibbs, P.2    O'Day, S.3
  • 108
    • 0036467376 scopus 로고    scopus 로고
    • Dynamics of the immunological synapse: finding, establishing and solidifying a connection
    • Krummel M.F., and Davis M.M. Dynamics of the immunological synapse: finding, establishing and solidifying a connection. Curr Opin Immunol 14 1 (2002) 66-74
    • (2002) Curr Opin Immunol , vol.14 , Issue.1 , pp. 66-74
    • Krummel, M.F.1    Davis, M.M.2
  • 109
    • 22544465538 scopus 로고    scopus 로고
    • A theoretical framework for quantitative analysis of the molecular basis of costimulation
    • Jansson A., Barnes E., Klenerman P., et al. A theoretical framework for quantitative analysis of the molecular basis of costimulation. J Immunol 175 3 (2005) 1575-1585
    • (2005) J Immunol , vol.175 , Issue.3 , pp. 1575-1585
    • Jansson, A.1    Barnes, E.2    Klenerman, P.3
  • 111
    • 11844251962 scopus 로고    scopus 로고
    • New cancer vaccine approaches
    • Kaplan J.M. New cancer vaccine approaches. Drugs of Today 40 11 (2004) 913-929
    • (2004) Drugs of Today , vol.40 , Issue.11 , pp. 913-929
    • Kaplan, J.M.1
  • 112
    • 4444329501 scopus 로고    scopus 로고
    • Cancer vaccine development: on the way to break immune tolerance to malignant cells
    • Mocellin S., Rossi C.R., and Nitti D. Cancer vaccine development: on the way to break immune tolerance to malignant cells. Exp Cell Res 299 2 (2004) 267-278
    • (2004) Exp Cell Res , vol.299 , Issue.2 , pp. 267-278
    • Mocellin, S.1    Rossi, C.R.2    Nitti, D.3
  • 113
    • 0033941834 scopus 로고    scopus 로고
    • T-cell clones from melanoma patients immunized against an anchor-modified gp100 peptide display discordant effector phenotypes
    • Dudley M.E., Ngo L.T., Westwood J., et al. T-cell clones from melanoma patients immunized against an anchor-modified gp100 peptide display discordant effector phenotypes. Cancer J 6 2 (2000) 69-77
    • (2000) Cancer J , vol.6 , Issue.2 , pp. 69-77
    • Dudley, M.E.1    Ngo, L.T.2    Westwood, J.3
  • 114
    • 0029979997 scopus 로고    scopus 로고
    • Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes
    • Topalian S.L., Gonzales M.I., Parkhurst M., et al. Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes. J Exp Med 183 5 (1996) 1965-1971
    • (1996) J Exp Med , vol.183 , Issue.5 , pp. 1965-1971
    • Topalian, S.L.1    Gonzales, M.I.2    Parkhurst, M.3
  • 115
    • 0031974381 scopus 로고    scopus 로고
    • CD4+ T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase
    • Kobayashi H., Kokubo T., Sato K., et al. CD4+ T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase. Cancer Res 58 2 (1998) 296-301
    • (1998) Cancer Res , vol.58 , Issue.2 , pp. 296-301
    • Kobayashi, H.1    Kokubo, T.2    Sato, K.3
  • 116
    • 0034602674 scopus 로고    scopus 로고
    • Melan-A/MART-1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells
    • Zarour H.M., Kirkwood J.M., Kierstead L.S., et al. Melan-A/MART-1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells. Proc Natl Acad Sci USA 97 1 (2000) 400-405
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.1 , pp. 400-405
    • Zarour, H.M.1    Kirkwood, J.M.2    Kierstead, L.S.3
  • 117
    • 0033103192 scopus 로고    scopus 로고
    • Melanoma cells present a MAGE-3 epitope to CD4(+) cytotoxic T cells in association with histocompatibility leukocyte antigen DR11
    • Manici S., Sturniolo T., Imro M.A., et al. Melanoma cells present a MAGE-3 epitope to CD4(+) cytotoxic T cells in association with histocompatibility leukocyte antigen DR11. J Exp Med 189 5 (1999) 871-876
    • (1999) J Exp Med , vol.189 , Issue.5 , pp. 871-876
    • Manici, S.1    Sturniolo, T.2    Imro, M.A.3
  • 118
    • 0033103512 scopus 로고    scopus 로고
    • Identification of MAGE-3 epitopes presented by HLA-DR molecules to CD4(+) T lymphocytes
    • Chaux P., Vantomme V., Stroobant V., et al. Identification of MAGE-3 epitopes presented by HLA-DR molecules to CD4(+) T lymphocytes. J Exp Med 189 5 (1999) 767-778
    • (1999) J Exp Med , vol.189 , Issue.5 , pp. 767-778
    • Chaux, P.1    Vantomme, V.2    Stroobant, V.3
  • 119
    • 24944459890 scopus 로고    scopus 로고
    • Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
    • Attia P., Phan G.Q., Maker A.V., et al. Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol 23 25 (2005) 6043-6053
    • (2005) J Clin Oncol , vol.23 , Issue.25 , pp. 6043-6053
    • Attia, P.1    Phan, G.Q.2    Maker, A.V.3
  • 120
    • 21844471782 scopus 로고    scopus 로고
    • Phase I study of a plasmid DNA vaccine encoding MART-1 in patients with resected melanoma at risk for relapse
    • Triozzi P.L., Aldrich W., Allen K.O., et al. Phase I study of a plasmid DNA vaccine encoding MART-1 in patients with resected melanoma at risk for relapse. J Immunother 28 4 (2005) 382-388
    • (2005) J Immunother , vol.28 , Issue.4 , pp. 382-388
    • Triozzi, P.L.1    Aldrich, W.2    Allen, K.O.3
  • 121
    • 33749237126 scopus 로고    scopus 로고
    • Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients
    • Jager E., Karbach J., Gnjatic S., et al. Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients. Proc Natl Acad Sci USA 103 39 (2006) 14453-14458
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.39 , pp. 14453-14458
    • Jager, E.1    Karbach, J.2    Gnjatic, S.3
  • 122
    • 33745831228 scopus 로고    scopus 로고
    • High-affinity interactions between peptides and heat shock protein 70 augment CD8+ T lymphocyte immune responses
    • Flechtner J.B., Cohane K.P., Mehta S., et al. High-affinity interactions between peptides and heat shock protein 70 augment CD8+ T lymphocyte immune responses. J Immunol 177 2 (2006) 1017-1027
    • (2006) J Immunol , vol.177 , Issue.2 , pp. 1017-1027
    • Flechtner, J.B.1    Cohane, K.P.2    Mehta, S.3
  • 123
    • 33646348754 scopus 로고    scopus 로고
    • A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-alpha in metastatic melanoma patients
    • Pilla L., Patuzzo R., Rivoltini L., et al. A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-alpha in metastatic melanoma patients. Cancer Immunol Immunother 55 8 (2006) 958-968
    • (2006) Cancer Immunol Immunother , vol.55 , Issue.8 , pp. 958-968
    • Pilla, L.1    Patuzzo, R.2    Rivoltini, L.3
  • 124
    • 0036784852 scopus 로고    scopus 로고
    • Prolonged survival of patients receiving active immunotherapy with Canvaxin therapeutic polyvalent vaccine after complete resection of melanoma metastatic to regional lymph nodes
    • Morton D.L., Hsueh E.C., Essner R., et al. Prolonged survival of patients receiving active immunotherapy with Canvaxin therapeutic polyvalent vaccine after complete resection of melanoma metastatic to regional lymph nodes. Ann Surg 236 4 (2002) 438-448
    • (2002) Ann Surg , vol.236 , Issue.4 , pp. 438-448
    • Morton, D.L.1    Hsueh, E.C.2    Essner, R.3
  • 125
    • 36049024424 scopus 로고    scopus 로고
    • Morton DL. Multicenter double-blind phase 3 trial of Canvaxin vs placebo as post surgical adjuvant in metastatic melanoma. Paper presented at Society of Surgical Oncology 59th Annual Cancer Symposium. San Diego (CA), March 24, 2006.
  • 126
    • 33845773464 scopus 로고    scopus 로고
    • Dendritic cell-based immunotherapy
    • Osada T., Clay T.M., Woo C.Y., et al. Dendritic cell-based immunotherapy. Int Rev Immunol 25 5-6 (2006) 377-413
    • (2006) Int Rev Immunol , vol.25 , Issue.5-6 , pp. 377-413
    • Osada, T.1    Clay, T.M.2    Woo, C.Y.3
  • 127
    • 3042728750 scopus 로고    scopus 로고
    • Pilot study of treatment of biochemotherapy-refractory stage IV melanoma patients with autologous dendritic cells pulsed with a heterologous melanoma cell line lysate
    • Vilella R., Benitez D., Mila J., et al. Pilot study of treatment of biochemotherapy-refractory stage IV melanoma patients with autologous dendritic cells pulsed with a heterologous melanoma cell line lysate. Cancer Immunol Immunother 53 7 (2004) 651-658
    • (2004) Cancer Immunol Immunother , vol.53 , Issue.7 , pp. 651-658
    • Vilella, R.1    Benitez, D.2    Mila, J.3
  • 128
    • 33645297917 scopus 로고    scopus 로고
    • Vaccination of melanoma patients using dendritic cells loaded with an allogeneic tumor cell lysate
    • Salcedo M., Bercovici N., Taylor R., et al. Vaccination of melanoma patients using dendritic cells loaded with an allogeneic tumor cell lysate. Cancer Immunol Immunother 55 7 (2006) 819-829
    • (2006) Cancer Immunol Immunother , vol.55 , Issue.7 , pp. 819-829
    • Salcedo, M.1    Bercovici, N.2    Taylor, R.3
  • 129
    • 27744517867 scopus 로고    scopus 로고
    • Immunization using autologous dendritic cells pulsed with the melanoma-associated antigen gp100-derived G280-9V peptide elicits CD8+ immunity
    • Linette G.P., Zhang D., Hodi F.S., et al. Immunization using autologous dendritic cells pulsed with the melanoma-associated antigen gp100-derived G280-9V peptide elicits CD8+ immunity. Clin Cancer Res 11 21 (2005) 7692-7699
    • (2005) Clin Cancer Res , vol.11 , Issue.21 , pp. 7692-7699
    • Linette, G.P.1    Zhang, D.2    Hodi, F.S.3
  • 130
    • 33746910738 scopus 로고    scopus 로고
    • Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
    • Kyte J.A., Mu L., Aamdal S., et al. Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA. Cancer Gene Ther 13 10 (2006) 905-918
    • (2006) Cancer Gene Ther , vol.13 , Issue.10 , pp. 905-918
    • Kyte, J.A.1    Mu, L.2    Aamdal, S.3
  • 131
    • 33750326077 scopus 로고    scopus 로고
    • Intralymphatic dendritic cell vaccination induces tumor antigen-specific, skin-homing T lymphocytes
    • Grover A., Kim G.J., Lizee G., et al. Intralymphatic dendritic cell vaccination induces tumor antigen-specific, skin-homing T lymphocytes. Clin Cancer Res 12 19 (2006) 5801-5808
    • (2006) Clin Cancer Res , vol.12 , Issue.19 , pp. 5801-5808
    • Grover, A.1    Kim, G.J.2    Lizee, G.3
  • 132
    • 33745603724 scopus 로고    scopus 로고
    • Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34(+) progenitor-derived dendritic cells
    • Fay J.W., Palucka A.K., Paczesny S., et al. Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34(+) progenitor-derived dendritic cells. Cancer Immunol Immunother 55 10 (2006) 1209-1218
    • (2006) Cancer Immunol Immunother , vol.55 , Issue.10 , pp. 1209-1218
    • Fay, J.W.1    Palucka, A.K.2    Paczesny, S.3
  • 133
    • 9144264534 scopus 로고    scopus 로고
    • Phase I/II trial of melanoma patient-specific vaccine of proliferating autologous tumor cells, dendritic cells, and GM-CSF: planned interim analysis
    • Dillman R., Selvan S., Schiltz P., et al. Phase I/II trial of melanoma patient-specific vaccine of proliferating autologous tumor cells, dendritic cells, and GM-CSF: planned interim analysis. Cancer Biother Radiopharm 19 5 (2004) 658-665
    • (2004) Cancer Biother Radiopharm , vol.19 , Issue.5 , pp. 658-665
    • Dillman, R.1    Selvan, S.2    Schiltz, P.3
  • 134
    • 33646400810 scopus 로고    scopus 로고
    • Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8 (+) T cells and monocyte/dendritic cell precursors
    • Di Pucchio T., Pilla L., Capone I., et al. Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8 (+) T cells and monocyte/dendritic cell precursors. Cancer Res 66 9 (2006) 4943-4951
    • (2006) Cancer Res , vol.66 , Issue.9 , pp. 4943-4951
    • Di Pucchio, T.1    Pilla, L.2    Capone, I.3
  • 135
    • 24144459856 scopus 로고    scopus 로고
    • Immune and clinical outcomes in patients with stage IV melanoma vaccinated with peptide-pulsed dendritic cells derived from CD34+ progenitors and activated with type I interferon
    • Banchereau J., Ueno H., Dhodapkar M., et al. Immune and clinical outcomes in patients with stage IV melanoma vaccinated with peptide-pulsed dendritic cells derived from CD34+ progenitors and activated with type I interferon. J Immunother 28 5 (2005) 505-516
    • (2005) J Immunother , vol.28 , Issue.5 , pp. 505-516
    • Banchereau, J.1    Ueno, H.2    Dhodapkar, M.3
  • 136
    • 33746257312 scopus 로고    scopus 로고
    • IL-12p70 and IL-18 gene-modified dendritic cells loaded with tumor antigen-derived peptides or recombinant protein effectively stimulate specific Type-1 CD4+ T-cell responses from normal donors and melanoma patients in vitro
    • Vujanovic L., Ranieri E., Gambotto A., et al. IL-12p70 and IL-18 gene-modified dendritic cells loaded with tumor antigen-derived peptides or recombinant protein effectively stimulate specific Type-1 CD4+ T-cell responses from normal donors and melanoma patients in vitro. Cancer Gene Ther 13 8 (2006) 798-805
    • (2006) Cancer Gene Ther , vol.13 , Issue.8 , pp. 798-805
    • Vujanovic, L.1    Ranieri, E.2    Gambotto, A.3
  • 137
    • 0036734775 scopus 로고    scopus 로고
    • The treatment of patients with disseminated malignant melanoma by vaccination with autologous cell hybrids of tumor cells and dendritic cells
    • Krause S.W., Neumann C., Soruri A., et al. The treatment of patients with disseminated malignant melanoma by vaccination with autologous cell hybrids of tumor cells and dendritic cells. J Immunother 25 5 (2002) 421-428
    • (2002) J Immunother , vol.25 , Issue.5 , pp. 421-428
    • Krause, S.W.1    Neumann, C.2    Soruri, A.3
  • 138
    • 33645222947 scopus 로고    scopus 로고
    • Dendritoma vaccination combined with low dose interleukin-2 in metastatic melanoma patients induced immunological and clinical responses
    • Wei Y., Sticca R.P., Holmes L.M., et al. Dendritoma vaccination combined with low dose interleukin-2 in metastatic melanoma patients induced immunological and clinical responses. Int J Oncol 28 3 (2006) 585-593
    • (2006) Int J Oncol , vol.28 , Issue.3 , pp. 585-593
    • Wei, Y.1    Sticca, R.P.2    Holmes, L.M.3
  • 139
    • 14844337815 scopus 로고    scopus 로고
    • Tumour-dendritic hybrid cell vaccination for the treatment of patients with malignant melanoma: immunological effects and clinical results
    • Trefzer U., Herberth G., Wohlan K., et al. Tumour-dendritic hybrid cell vaccination for the treatment of patients with malignant melanoma: immunological effects and clinical results. Vaccine 23 17-18 (2005) 2367-2373
    • (2005) Vaccine , vol.23 , Issue.17-18 , pp. 2367-2373
    • Trefzer, U.1    Herberth, G.2    Wohlan, K.3
  • 140
    • 11244313924 scopus 로고    scopus 로고
    • Dendritic cells derived from metastatic cancer patients vaccinated with allogeneic dendritic cell-autologous tumor cell hybrids express more CD86 and induce higher levels of interferon-gamma in mixed lymphocyte reactions
    • Neves A.R., Ensina L.F., Anselmo L.B., et al. Dendritic cells derived from metastatic cancer patients vaccinated with allogeneic dendritic cell-autologous tumor cell hybrids express more CD86 and induce higher levels of interferon-gamma in mixed lymphocyte reactions. Cancer Immunol Immunother 54 1 (2005) 61-66
    • (2005) Cancer Immunol Immunother , vol.54 , Issue.1 , pp. 61-66
    • Neves, A.R.1    Ensina, L.F.2    Anselmo, L.B.3
  • 141
    • 2942541155 scopus 로고    scopus 로고
    • Vaccination with hybrids of tumor and dendritic cells induces tumor-specific T-cell and clinical responses in melanoma stage III and IV patients
    • Trefzer U., Herberth G., Wohlan K., et al. Vaccination with hybrids of tumor and dendritic cells induces tumor-specific T-cell and clinical responses in melanoma stage III and IV patients. Int J Cancer 110 5 (2004) 730-740
    • (2004) Int J Cancer , vol.110 , Issue.5 , pp. 730-740
    • Trefzer, U.1    Herberth, G.2    Wohlan, K.3
  • 142
    • 1442336031 scopus 로고    scopus 로고
    • Hybrid cell vaccination in metastatic melanoma: clinical and immunologic results of a phase I/II study
    • Haenssle H.A., Krause S.W., Emmert S., et al. Hybrid cell vaccination in metastatic melanoma: clinical and immunologic results of a phase I/II study. J Immunother 27 2 (2004) 147-155
    • (2004) J Immunother , vol.27 , Issue.2 , pp. 147-155
    • Haenssle, H.A.1    Krause, S.W.2    Emmert, S.3
  • 143
    • 0642311904 scopus 로고    scopus 로고
    • Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells
    • Slingluff Jr. C.L., Petroni G.R., Yamshchikov G.V., et al. Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells. J Clin Oncol 21 21 (2003) 4016-4026
    • (2003) J Clin Oncol , vol.21 , Issue.21 , pp. 4016-4026
    • Slingluff Jr., C.L.1    Petroni, G.R.2    Yamshchikov, G.V.3
  • 144
    • 4344614603 scopus 로고    scopus 로고
    • Characterization of long-term effector-memory T-cell responses in patients with resected high-risk melanoma receiving a melanoma peptide vaccine
    • Chiong B., Wong R., Lee P., et al. Characterization of long-term effector-memory T-cell responses in patients with resected high-risk melanoma receiving a melanoma peptide vaccine. J Immunother 27 5 (2004) 368-379
    • (2004) J Immunother , vol.27 , Issue.5 , pp. 368-379
    • Chiong, B.1    Wong, R.2    Lee, P.3
  • 145
    • 33846064604 scopus 로고    scopus 로고
    • Adjuvant trastuzumab: a milestone in the treatment of HER-2-positive early breast cancer
    • Baselga J., Perez E.A., Pienkowski T., et al. Adjuvant trastuzumab: a milestone in the treatment of HER-2-positive early breast cancer. Oncologist 11 Suppl 1 (2006) 4-12
    • (2006) Oncologist , vol.11 , Issue.SUPPL. 1 , pp. 4-12
    • Baselga, J.1    Perez, E.A.2    Pienkowski, T.3
  • 146
    • 33748107226 scopus 로고    scopus 로고
    • Rituximab for the treatment of diffuse large B-cell lymphomas
    • Held G., Poschel V., and Pfreundschuh M. Rituximab for the treatment of diffuse large B-cell lymphomas. Expert Rev Anticancer Ther 6 8 (2006) 1175-1186
    • (2006) Expert Rev Anticancer Ther , vol.6 , Issue.8 , pp. 1175-1186
    • Held, G.1    Poschel, V.2    Pfreundschuh, M.3
  • 147
    • 33645280860 scopus 로고    scopus 로고
    • Phase I trial of combined treatment with ch14.18 and R24 monoclonal antibodies and interleukin-2 for patients with melanoma or sarcoma
    • Choi B.S., Sondel P.M., Hank J.A., et al. Phase I trial of combined treatment with ch14.18 and R24 monoclonal antibodies and interleukin-2 for patients with melanoma or sarcoma. Cancer Immunol Immunother 55 7 (2006) 761-774
    • (2006) Cancer Immunol Immunother , vol.55 , Issue.7 , pp. 761-774
    • Choi, B.S.1    Sondel, P.M.2    Hank, J.A.3
  • 148
    • 0020594301 scopus 로고
    • Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells
    • Grimm E.A., Ramsey K.M., Mazumder A., et al. Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells. J Exp Med 157 3 (1983) 884-897
    • (1983) J Exp Med , vol.157 , Issue.3 , pp. 884-897
    • Grimm, E.A.1    Ramsey, K.M.2    Mazumder, A.3
  • 149
    • 0024791076 scopus 로고
    • Lymphokine activated killer cells
    • Lindemann A., Herrmann F., Oster W., et al. Lymphokine activated killer cells. Blut 59 4 (1989) 375-384
    • (1989) Blut , vol.59 , Issue.4 , pp. 375-384
    • Lindemann, A.1    Herrmann, F.2    Oster, W.3
  • 150
    • 0037829421 scopus 로고    scopus 로고
    • Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
    • Dudley M.E., Wunderlich J.R., Shelton T.E., et al. Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J Immunother 26 4 (2003) 332-342
    • (2003) J Immunother , vol.26 , Issue.4 , pp. 332-342
    • Dudley, M.E.1    Wunderlich, J.R.2    Shelton, T.E.3
  • 151
    • 0037334781 scopus 로고    scopus 로고
    • Adjuvant immunotherapy with tumor infiltrating lymphocytes and interleukin-2 in patients with resected stage III and IV melanoma
    • Ridolfi L., Ridolfi R., Riccobon A., et al. Adjuvant immunotherapy with tumor infiltrating lymphocytes and interleukin-2 in patients with resected stage III and IV melanoma. J Immunother 26 2 (2003) 156-162
    • (2003) J Immunother , vol.26 , Issue.2 , pp. 156-162
    • Ridolfi, L.1    Ridolfi, R.2    Riccobon, A.3
  • 152
    • 20244366111 scopus 로고    scopus 로고
    • Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
    • Dudley M.E., Wunderlich J.R., Yang J.C., et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol 23 10 (2005) 2346-2357
    • (2005) J Clin Oncol , vol.23 , Issue.10 , pp. 2346-2357
    • Dudley, M.E.1    Wunderlich, J.R.2    Yang, J.C.3
  • 153
    • 33750324618 scopus 로고    scopus 로고
    • Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes
    • Johnson L.A., Heemskerk B., Powell Jr. D.J., et al. Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes. J Immunol 177 9 (2006) 6548-6559
    • (2006) J Immunol , vol.177 , Issue.9 , pp. 6548-6559
    • Johnson, L.A.1    Heemskerk, B.2    Powell Jr., D.J.3
  • 154
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • Morgan R.A., Dudley M.E., Wunderlich J.R., et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314 5796 (2006) 126-129
    • (2006) Science , vol.314 , Issue.5796 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3
  • 155
    • 13744257906 scopus 로고    scopus 로고
    • Carcinoembryonic antigen-immunoglobulin Fc fusion protein (CEA-Fc) for identification and activation of anti-CEA immunoglobulin-T-cell receptor-modified T cells, representative of a new class of Ig fusion proteins
    • Ma Q., DeMarte L., Wang Y., et al. Carcinoembryonic antigen-immunoglobulin Fc fusion protein (CEA-Fc) for identification and activation of anti-CEA immunoglobulin-T-cell receptor-modified T cells, representative of a new class of Ig fusion proteins. Cancer Gene Ther 11 4 (2004) 297-306
    • (2004) Cancer Gene Ther , vol.11 , Issue.4 , pp. 297-306
    • Ma, Q.1    DeMarte, L.2    Wang, Y.3
  • 156
    • 4143084967 scopus 로고    scopus 로고
    • Anti-prostate specific membrane antigen designer T cells for prostate cancer therapy
    • Ma Q., Safar M., Holmes E., et al. Anti-prostate specific membrane antigen designer T cells for prostate cancer therapy. Prostate 61 1 (2004) 12-25
    • (2004) Prostate , vol.61 , Issue.1 , pp. 12-25
    • Ma, Q.1    Safar, M.2    Holmes, E.3
  • 157
    • 0034526330 scopus 로고    scopus 로고
    • Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors
    • Yun C.O., Nolan K.F., Beecham E.J., et al. Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors. Neoplasia 2 5 (2000) 449-459
    • (2000) Neoplasia , vol.2 , Issue.5 , pp. 449-459
    • Yun, C.O.1    Nolan, K.F.2    Beecham, E.J.3
  • 158
    • 0032955712 scopus 로고    scopus 로고
    • Specific lysis of melanoma cells by receptor grafted T cells is enhanced by anti-idiotypic monoclonal antibodies directed to the scFv domain of the receptor
    • Reinhold U., Liu L., Ludtke-Handjery H.C., et al. Specific lysis of melanoma cells by receptor grafted T cells is enhanced by anti-idiotypic monoclonal antibodies directed to the scFv domain of the receptor. J Investigative Dermatology 112 5 (1999) 744-750
    • (1999) J Investigative Dermatology , vol.112 , Issue.5 , pp. 744-750
    • Reinhold, U.1    Liu, L.2    Ludtke-Handjery, H.C.3
  • 159
    • 0035226813 scopus 로고    scopus 로고
    • A novel strategy in the elimination of disseminated melanoma cells: chimeric receptors endow T cells with tumor specificity
    • Abken H., Hombach A., Heuser C., et al. A novel strategy in the elimination of disseminated melanoma cells: chimeric receptors endow T cells with tumor specificity. Recent Results Cancer Res 158 (2001) 249-264
    • (2001) Recent Results Cancer Res , vol.158 , pp. 249-264
    • Abken, H.1    Hombach, A.2    Heuser, C.3


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