메뉴 건너뛰기




Volumn 58, Issue 12, 1998, Pages 2489-2499

Biological properties of recombinant α-interferons: 40th Anniversary of the discovery of interferons

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON RECEPTOR; ALPHA2 INTERFERON; ARACHIDONIC ACID; BUSULFAN; CARCINOEMBRYONIC ANTIGEN; CELL SURFACE RECEPTOR; DOXORUBICIN; FIBRONECTIN; FLUOROURACIL; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HYDROXYUREA; IMMUNOGLOBULIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 1; INTERLEUKIN 8; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PHOSPHOLIPASE A2; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; RECOMBINANT ALPHA INTERFERON; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR;

EID: 0032526030     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (463)

References (166)
  • 2
    • 0019759680 scopus 로고
    • Induction of chick interferon: Procedures of the original experiments
    • Lindenmann, J. Induction of chick interferon: procedures of the original experiments. Methods Enzymol., 78: 181-188, 1981.
    • (1981) Methods Enzymol. , vol.78 , pp. 181-188
    • Lindenmann, J.1
  • 3
    • 0030945648 scopus 로고    scopus 로고
    • The human interferon-α species and hybrid proteins
    • Pestka, S. The human interferon-α species and hybrid proteins. Semin. Oncol., 24 (Suppl. 9): S9-4-S9-17, 1997.
    • (1997) Semin. Oncol. , vol.24 , Issue.9 SUPPL.
    • Pestka, S.1
  • 4
    • 0345092577 scopus 로고
    • Human interferon α family: Protein structure and function
    • S. Baron, D. H. Coopenhaver, F. Dianzani, W. R. Fleishmann, T. K. Hughes, Jr., G. R. Kimpel, Jr., D. W. Niesel, G. J. Stanton, and S. K. Tyring (eds.), Galveston, TX: The University of Texas Medical Branch at Galveston
    • Zoon, K. C., Bekisz, J., and Miller, D. Human interferon α family: protein structure and function. In: S. Baron, D. H. Coopenhaver, F. Dianzani, W. R. Fleishmann, T. K. Hughes, Jr., G. R. Kimpel, Jr., D. W. Niesel, G. J. Stanton, and S. K. Tyring (eds.), Interferon: Principles and Medical Applications, pp. 95-105. Galveston, TX: The University of Texas Medical Branch at Galveston, 1992.
    • (1992) Interferon: Principles and Medical Applications , pp. 95-105
    • Zoon, K.C.1    Bekisz, J.2    Miller, D.3
  • 5
    • 0025015138 scopus 로고
    • Genetic transfer of a functional human interferon α receptor into mouse cells: Cloning and expression of its cDNA
    • Uzé, G., Lutfalla, G., and Gresser, I. Genetic transfer of a functional human interferon α receptor into mouse cells: cloning and expression of its cDNA. Cell, 60: 225-234, 1990.
    • (1990) Cell , vol.60 , pp. 225-234
    • Uzé, G.1    Lutfalla, G.2    Gresser, I.3
  • 6
    • 0029148972 scopus 로고
    • Cloning and expression of a long form of the β-subunit of the interferon αβ receptor that is required for signaling
    • Domanski, P., Witte, M., Kellum, M., Rubinstein, M., Hackett, R., Pitha, P., and Colamonici, O. R. Cloning and expression of a long form of the β-subunit of the interferon αβ receptor that is required for signaling. J. Biol. Chem., 270: 21606-21611, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21606-21611
    • Domanski, P.1    Witte, M.2    Kellum, M.3    Rubinstein, M.4    Hackett, R.5    Pitha, P.6    Colamonici, O.R.7
  • 7
    • 0028299340 scopus 로고
    • The human interferon α/β receptor: Characterization and molecular cloning
    • Novick, D., Cohen, B., and Rubinstein, M. The human interferon α/β receptor: characterization and molecular cloning. Cell, 77: 391-400, 1994.
    • (1994) Cell , vol.77 , pp. 391-400
    • Novick, D.1    Cohen, B.2    Rubinstein, M.3
  • 8
    • 0028820423 scopus 로고
    • Mutant U5a cells are complemented by an interferon-αβ receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster
    • Lutfalla, G., Holland, S. J., Cinato, E., Monneron, D., Reboul, J., Rogers, N. C., Smith, J. M., Stark, G. R., Gardiner, K., Mogensen, K. E., Kerr, I. M., and Uzé, G. Mutant U5A cells are complemented by an interferon-αβ receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster. EMBO J., 14: 5100-5108, 1995.
    • (1995) EMBO J. , vol.14 , pp. 5100-5108
    • Lutfalla, G.1    Holland, S.J.2    Cinato, E.3    Monneron, D.4    Reboul, J.5    Rogers, N.C.6    Smith, J.M.7    Stark, G.R.8    Gardiner, K.9    Mogensen, K.E.10    Kerr, I.M.11    Uzé, G.12
  • 9
    • 0030207074 scopus 로고    scopus 로고
    • The type-I interferon receptor. The long and short of it
    • Domanski, P., and Colamonici, O. R. The type-I interferon receptor. The long and short of it. Cytokine Growth Factor Rev., 7: 143-151, 1996.
    • (1996) Cytokine Growth Factor Rev. , vol.7 , pp. 143-151
    • Domanski, P.1    Colamonici, O.R.2
  • 12
    • 0026739463 scopus 로고
    • The interferon system: A bird's eye view of its biochemistry
    • Sen, G. C., and Lengyel, P. The interferon system: a bird's eye view of its biochemistry. J. Biol. Chem., 267: 5017-5020, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5017-5020
    • Sen, G.C.1    Lengyel, P.2
  • 14
    • 0141931578 scopus 로고
    • Interferon α2b: An overview from a regulatory perspective
    • A. S. Lubiniecki and S. A. Vargo (eds.), New York: Wiley-Liss
    • Nagabhushan, T. L., and Giaquinto, A. Interferon α2b: an overview from a regulatory perspective. In: A. S. Lubiniecki and S. A. Vargo (eds.), Regulatory Practice for Biopharmaceutical Production, pp. 221-234. New York: Wiley-Liss, 1994.
    • (1994) Regulatory Practice for Biopharmaceutical Production , pp. 221-234
    • Nagabhushan, T.L.1    Giaquinto, A.2
  • 18
    • 0001876236 scopus 로고
    • Production, characterization and biological effects of recombinant DNA derived human IFN-α and IFN-γ analogs
    • E. DeMaeyer and H. Schellekens (eds.), Amsterdam: Elsevier
    • Alton, K. Y., Stabinsky, R., Richards, R., Ferguson, B., Goldstein, L., Altrock, B., Miller, L., and Stebbing, N. Production, characterization and biological effects of recombinant DNA derived human IFN-α and IFN-γ analogs. In: E. DeMaeyer and H. Schellekens (eds.), The Biology of the Interferon System, pp. 119-128. Amsterdam: Elsevier, 1983.
    • (1983) The Biology of the Interferon System , pp. 119-128
    • Alton, K.Y.1    Stabinsky, R.2    Richards, R.3    Ferguson, B.4    Goldstein, L.5    Altrock, B.6    Miller, L.7    Stebbing, N.8
  • 20
    • 0028944489 scopus 로고
    • α and β interferons and their receptor and their friends and relatives
    • Uzé, G., Lutfalla, G., and Mogensen, K. E. α and β interferons and their receptor and their friends and relatives. J. Interferon Cytokine Res., 15: 3-26, 1995.
    • (1995) J. Interferon Cytokine Res. , vol.15 , pp. 3-26
    • Uzé, G.1    Lutfalla, G.2    Mogensen, K.E.3
  • 21
    • 0028225872 scopus 로고
    • Knockout and reconstitution of a functional human type I interferon receptor complex
    • Cleary, C. M., Donnelly, R. J., Soh, J., Mariano, T. M., and Pestka, S. Knockout and reconstitution of a functional human type I interferon receptor complex. J. Biol. Chem., 269: 18747-18749, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18747-18749
    • Cleary, C.M.1    Donnelly, R.J.2    Soh, J.3    Mariano, T.M.4    Pestka, S.5
  • 22
    • 0029993080 scopus 로고    scopus 로고
    • Differential responsiveness of a splice variant of the human type I interferon receptor to interferons
    • Cook, J. R., Cleary, C. M., Mariano, T. M., Izotova, L., and Pestka, S. Differential responsiveness of a splice variant of the human type I interferon receptor to interferons. J. Biol. Chem., 271: 13448-13453, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13448-13453
    • Cook, J.R.1    Cleary, C.M.2    Mariano, T.M.3    Izotova, L.4    Pestka, S.5
  • 23
    • 0028361818 scopus 로고
    • Expression of a functional human type I interferon receptor in hamster cells: Application of functional yeast artificial chromosome (YAC) screening
    • Soh, J., Mariano, T. M., Lim, J-K., Izotova, L., Mirochnitchenko, O., Schwartz, B., Langer, J. A., and Pestka, S. Expression of a functional human type I interferon receptor in hamster cells: application of functional yeast artificial chromosome (YAC) screening. J. Biol. Chem., 269: 18102-18110, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18102-18110
    • Soh, J.1    Mariano, T.M.2    Lim, J.-K.3    Izotova, L.4    Mirochnitchenko, O.5    Schwartz, B.6    Langer, J.A.7    Pestka, S.8
  • 24
    • 0030994132 scopus 로고    scopus 로고
    • The interferon receptors
    • Pestka, S. The interferon receptors. Semin. Oncol., 24 (Suppl. 9): S9-18-S9-40, 1997.
    • (1997) Semin. Oncol. , vol.24 , Issue.9 SUPPL.
    • Pestka, S.1
  • 25
    • 0028070714 scopus 로고
    • Functional role of type I and type II interferons in antiviral defense
    • Washington DC
    • Müller, U., Steinhoff, U., Reis, L. F., Hemmi, S., Pavlovic, J., Zinkernagel, R. M., and Aguet, M. Functional role of type I and type II interferons in antiviral defense. Science (Washington DC), 264: 1918-1921, 1994.
    • (1994) Science , vol.264 , pp. 1918-1921
    • Müller, U.1    Steinhoff, U.2    Reis, L.F.3    Hemmi, S.4    Pavlovic, J.5    Zinkernagel, R.M.6    Aguet, M.7
  • 26
    • 0028864798 scopus 로고
    • A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons α and β and alters macrophage responses
    • Hwang, S. Y., Hertzog, P. J., Holland, K. A., Sumarsono, S. H., Tymms, M. J., Hamilton, J. A., Whitty, G., Bertoncello, I., and Kola, I. A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons α and β and alters macrophage responses. Proc. Natl. Acad. Sci. USA, 92: 11284-11288, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11284-11288
    • Hwang, S.Y.1    Hertzog, P.J.2    Holland, K.A.3    Sumarsono, S.H.4    Tymms, M.J.5    Hamilton, J.A.6    Whitty, G.7    Bertoncello, I.8    Kola, I.9
  • 29
    • 0029863420 scopus 로고    scopus 로고
    • Molecular characterization of an α-interferon receptor 1 subunit (IFNαR1) domain required for TYK2 binding and signal transduction
    • Yan, H., Krishnan, K., Lim, J. T., Contillo, L. G., and Krolewski, J. J. Molecular characterization of an α-interferon receptor 1 subunit (IFNαR1) domain required for TYK2 binding and signal transduction. Mol. Cell. Biol., 16: 2074-2082, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2074-2082
    • Yan, H.1    Krishnan, K.2    Lim, J.T.3    Contillo, L.G.4    Krolewski, J.J.5
  • 31
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Washington DC
    • Darnell, J. E., Jr., Kerr, I. M., and Stark, G. R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science (Washington DC), 264: 1415-1421, 1994.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 32
    • 0028925284 scopus 로고
    • A direct signaling pathway through tyrosine kinase activation of SH2 domain-containing transcription factors
    • Fu, X-Y. A direct signaling pathway through tyrosine kinase activation of SH2 domain-containing transcription factors. J. Leukoc. Biol., 57: 529-535, 1995.
    • (1995) J. Leukoc. Biol. , vol.57 , pp. 529-535
    • Fu, X.-Y.1
  • 33
    • 0028107016 scopus 로고
    • Role of interferon α/β receptor chain 1 in the structure and transmembrane signaling of the interferon α/β receptor complex
    • Constantinescu, S. N., Croze, E., Wang, C., Murti, A., Basu, L., Mullersman, J. E., and Pfeffer, L. M. Role of interferon α/β receptor chain 1 in the structure and transmembrane signaling of the interferon α/β receptor complex. Proc. Natl. Acad. Sci. USA, 91: 9602-9606, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9602-9606
    • Constantinescu, S.N.1    Croze, E.2    Wang, C.3    Murti, A.4    Basu, L.5    Mullersman, J.E.6    Pfeffer, L.M.7
  • 36
    • 0020479984 scopus 로고
    • Interferon receptors: Cross linking of human leukocyte interferon α-2 to its receptor on human cells
    • Joshi, A. R., Sarkar, F. H., and Gupta, S. L. Interferon receptors: cross linking of human leukocyte interferon α-2 to its receptor on human cells. J. Biol. Chem., 257: 13884-13887, 1982.
    • (1982) J. Biol. Chem. , vol.257 , pp. 13884-13887
    • Joshi, A.R.1    Sarkar, F.H.2    Gupta, S.L.3
  • 37
    • 0024214006 scopus 로고
    • Characterization of interferon-α binding sites on human cell lines
    • Vanden Broecke, C., and Pfeffer, L. M. Characterization of interferon-α binding sites on human cell lines. J. Interferon Res., 8: 803-811, 1988.
    • (1988) J. Interferon Res. , vol.8 , pp. 803-811
    • Vanden Broecke, C.1    Pfeffer, L.M.2
  • 38
    • 0028271922 scopus 로고
    • A gene on human chromosome 21 located in the region 21q22.2 to 21q22.3 encodes a factor necessary for signal transduction and antiviral response to type I interferons
    • Hertzog, P. J., Hwang, S. Y., Holland, K. A., Tymms, M. J., Iannello, R., and Kila, I. A gene on human chromosome 21 located in the region 21q22.2 to 21q22.3 encodes a factor necessary for signal transduction and antiviral response to type I interferons. J. Biol. Chem., 269: 14088-14093, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14088-14093
    • Hertzog, P.J.1    Hwang, S.Y.2    Holland, K.A.3    Tymms, M.J.4    Iannello, R.5    Kila, I.6
  • 39
    • 0027980332 scopus 로고
    • The human interferon α-receptor protein confers differential responses to human interferon-β versus interferon-α subtypes in mouse and hamster cell transfectants
    • Abramovich, C., Chebath, J., and Revel, M. The human interferon α-receptor protein confers differential responses to human interferon-β versus interferon-α subtypes in mouse and hamster cell transfectants. Cytokine, 6: 414-424, 1994.
    • (1994) Cytokine , vol.6 , pp. 414-424
    • Abramovich, C.1    Chebath, J.2    Revel, M.3
  • 40
    • 0026054930 scopus 로고
    • Molecular-cloning of interferon receptors: A short review
    • Aguet, A. Molecular-cloning of interferon receptors: a short review. Br. J. Haematol., 79 (Suppl. 1): 6-8, 1991.
    • (1991) Br. J. Haematol. , vol.79 , Issue.1 SUPPL. , pp. 6-8
    • Aguet, A.1
  • 41
    • 45549117142 scopus 로고
    • Interferon receptors
    • Langer, J. A., and Pestka, S. Interferon receptors. Immunol. Today, 9: 393-400, 1988.
    • (1988) Immunol. Today , vol.9 , pp. 393-400
    • Langer, J.A.1    Pestka, S.2
  • 42
    • 0024321970 scopus 로고
    • The cellular receptor of the α-β interferons
    • Basel
    • Mogensen, K. E., Uzé, G., and Eid, P. The cellular receptor of the α-β interferons. Experientia (Basel), 45: 500-508, 1989.
    • (1989) Experientia , vol.45 , pp. 500-508
    • Mogensen, K.E.1    Uzé, G.2    Eid, P.3
  • 43
    • 0023236357 scopus 로고
    • Cytoskeletal association of human α-interferon-receptor complexes in interferon-sensitive and -resistant lymphoblastoid cells
    • Pfeffer, L. M., Stebbing, N., and Donner, D. B. Cytoskeletal association of human α-interferon-receptor complexes in interferon-sensitive and -resistant lymphoblastoid cells. Proc. Natl. Acad. Sci. USA, 84: 3249-3253, 1987.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 3249-3253
    • Pfeffer, L.M.1    Stebbing, N.2    Donner, D.B.3
  • 44
    • 0025360452 scopus 로고
    • Antiproliferative and antitumor effects of α-interferon in renal cell carcinomas: Correlation with the expression of a kidney-associated differentiation glycoprotein
    • Nanus, D. M., Pfeffer, L. M., Bander, N. H., Bahri, S., and Albino, A. P. Antiproliferative and antitumor effects of α-interferon in renal cell carcinomas: correlation with the expression of a kidney-associated differentiation glycoprotein. Cancer Res., 50: 4190-4194, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 4190-4194
    • Nanus, D.M.1    Pfeffer, L.M.2    Bander, N.H.3    Bahri, S.4    Albino, A.P.5
  • 45
    • 0025356871 scopus 로고
    • The down-regulation of α-interferon receptors in human lymphoblastoid cells: Relation to cellular responsiveness to the antiproliferative action of α-interferon
    • Pfeffer, L. M., and Donner, D. B. The down-regulation of α-interferon receptors in human lymphoblastoid cells: relation to cellular responsiveness to the antiproliferative action of α-interferon. Cancer Res., 50: 2654-2657, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 2654-2657
    • Pfeffer, L.M.1    Donner, D.B.2
  • 46
    • 0021022689 scopus 로고
    • Comparison of the effects of α and β interferons on the proliferation and volume of human tumor cells (HeLa-S3, Daudi, P3HR-1)
    • Pfeffer, L. M., and Tamm, I. Comparison of the effects of α and β interferons on the proliferation and volume of human tumor cells (HeLa-S3, Daudi, P3HR-1). J. Interferon Res., 3: 395-408, 1983.
    • (1983) J. Interferon Res. , vol.3 , pp. 395-408
    • Pfeffer, L.M.1    Tamm, I.2
  • 47
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler, C., and Darnell, J. E., Jr. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem., 64: 621-651, 1995.
    • (1995) Annu. Rev. Biochem. , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell Jr., J.E.2
  • 48
    • 0025797722 scopus 로고
    • Transcriptional regulation of interferon-stimulated genes
    • Williams, B. R. G. Transcriptional regulation of interferon-stimulated genes. Eur. J. Biochem., 200: 1-11, 1991.
    • (1991) Eur. J. Biochem. , vol.200 , pp. 1-11
    • Williams, B.R.G.1
  • 49
    • 0027933635 scopus 로고
    • Identification and characterization of an interferon (IFN)-stimulated response element-IFN-stimulated gene factor 3-independent signaling pathway for IFN-α
    • Haque, S. J., and Williams, B. R. G. Identification and characterization of an interferon (IFN)-stimulated response element-IFN-stimulated gene factor 3-independent signaling pathway for IFN-α. J. Biol. Chem., 269: 19523-19529, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 19523-19529
    • Haque, S.J.1    Williams, B.R.G.2
  • 50
    • 0027390602 scopus 로고
    • A novel interferon-inducible domain: Structural and functional analysis of the human interferon regulatory factor 1 gene promoter
    • Sims, S. H., Cha, Y., Romine, M. F., Gao, P-Q., Gottlieb, K., and Deisseroth, A. B. A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter. Mol. Cell. Biol., 13: 690-702, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 690-702
    • Sims, S.H.1    Cha, Y.2    Romine, M.F.3    Gao, P.-Q.4    Gottlieb, K.5    Deisseroth, A.B.6
  • 51
    • 0029670488 scopus 로고    scopus 로고
    • 2 is required for the formation of interferon-stimulated gene factor 3
    • 2 is required for the formation of interferon-stimulated gene factor 3. EMBO J., 15: 1566-1571, 1996.
    • (1996) EMBO J. , vol.15 , pp. 1566-1571
    • Flati, V.1    Haque, S.J.2    Williams, B.R.G.3
  • 52
    • 0026027850 scopus 로고
    • Signal transduction by interferon-α through arachidonic acid metabolism
    • Washington DC
    • Hannigan, G. E., and Williams, B. R. G. Signal transduction by interferon-α through arachidonic acid metabolism. Science (Washington DC), 251: 204-207, 1991.
    • (1991) Science , vol.251 , pp. 204-207
    • Hannigan, G.E.1    Williams, B.R.G.2
  • 53
    • 0027352378 scopus 로고
    • Interferon-induced antiviral actions and their regulation
    • Sen, G. C., and Ransohoff, R. M. Interferon-induced antiviral actions and their regulation. Adv. Virus Res., 42: 57-101, 1993.
    • (1993) Adv. Virus Res. , vol.42 , pp. 57-101
    • Sen, G.C.1    Ransohoff, R.M.2
  • 54
    • 0342535752 scopus 로고
    • Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element
    • Reich, N. C., Evans, B., Levy, D., Fahey, D., Knight, E., Jr., and Darnell, J. E., Jr. Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc. Natl. Acad. Sci. USA, 84: 6394-6398, 1987.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 6394-6398
    • Reich, N.C.1    Evans, B.2    Levy, D.3    Fahey, D.4    Knight Jr., E.5    Darnell Jr., J.E.6
  • 56
    • 0028117163 scopus 로고
    • Cytokine signal transduction
    • Kishimoto, T., Taga, T., and Akira, S. Cytokine signal transduction. Cell, 76: 253-262, 1994.
    • (1994) Cell , vol.76 , pp. 253-262
    • Kishimoto, T.1    Taga, T.2    Akira, S.3
  • 57
    • 0029887863 scopus 로고    scopus 로고
    • An overview of the interferon system: Signal transduction and mechanisms of action
    • Kalvakolanu, D. V., and Borden, E. C. An overview of the interferon system: signal transduction and mechanisms of action. Cancer Investig., 14: 25-53, 1996.
    • (1996) Cancer Investig. , vol.14 , pp. 25-53
    • Kalvakolanu, D.V.1    Borden, E.C.2
  • 58
    • 0030998984 scopus 로고    scopus 로고
    • Biologic activities of natural and synthetic type I interferons
    • Pfeffer, L. M. Biologic activities of natural and synthetic type I interferons. Semin. Oncol., 24 (Suppl. 9): S9-63-S9-69, 1997.
    • (1997) Semin. Oncol. , vol.24 , Issue.9 SUPPL.
    • Pfeffer, L.M.1
  • 59
    • 0030945650 scopus 로고    scopus 로고
    • Effect of α-interferons on immune function
    • Herberman, R. B. Effect of α-interferons on immune function. Semin. Oncol., 24 (Suppl. 9): S9-78-S9-80, 1997.
    • (1997) Semin. Oncol. , vol.24 , Issue.9 SUPPL.
    • Herberman, R.B.1
  • 60
    • 0020611528 scopus 로고
    • Effects of several species of human leukocyte interferon on cytotoxic activity of NK cells and monocytes
    • Ortaldo, J. R., Mantovani, A., Hobbs, D., Rubinstein, M., Pestka, S., and Herberman, R. B. Effects of several species of human leukocyte interferon on cytotoxic activity of NK cells and monocytes. Int. J. Cancer, 31: 285-289, 1983.
    • (1983) Int. J. Cancer , vol.31 , pp. 285-289
    • Ortaldo, J.R.1    Mantovani, A.2    Hobbs, D.3    Rubinstein, M.4    Pestka, S.5    Herberman, R.B.6
  • 61
    • 0020972966 scopus 로고
    • Effects of recombinant and hybrid recombinant human leukocyte interferons on cytotoxic activity of natural killer cells
    • Ortaldo, J. R., Mason, A., Rehberg, E., Moschera, J., Kelder, B., Pestka, S., and Herberman, R. B. Effects of recombinant and hybrid recombinant human leukocyte interferons on cytotoxic activity of natural killer cells. J. Biol. Chem., 24: 15001-15015, 1983.
    • (1983) J. Biol. Chem. , vol.24 , pp. 15001-15015
    • Ortaldo, J.R.1    Mason, A.2    Rehberg, E.3    Moschera, J.4    Kelder, B.5    Pestka, S.6    Herberman, R.B.7
  • 64
    • 0022555754 scopus 로고
    • Interferon from 1981 to 1986
    • S. Pestka (ed.), New York: Academic Press
    • Pestka, S. Interferon from 1981 to 1986. In: S. Pestka (ed.), Methods in Enzymology, Vol. 119, pp. 3-14. New York: Academic Press, 1986.
    • (1986) Methods in Enzymology , vol.119 , pp. 3-14
    • Pestka, S.1
  • 65
    • 0020450948 scopus 로고
    • Interferon-dependent induction of mRNA for the major histocompatibility antigens in human fibroblasts and lymphoblastoid cells
    • Fellous, M., Nir, U., Wallach, D., Merlin, G., Rubinstein, M., and Revel, M. Interferon-dependent induction of mRNA for the major histocompatibility antigens in human fibroblasts and lymphoblastoid cells. Proc. Natl. Acad. Sci. USA, 79: 3082-3086, 1982.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 3082-3086
    • Fellous, M.1    Nir, U.2    Wallach, D.3    Merlin, G.4    Rubinstein, M.5    Revel, M.6
  • 67
    • 0028985113 scopus 로고
    • Interferon-α activates cytotoxic function but inhibits interleukin-2-mediated proliferation and tumor necrosis factor-α secretion by immature human natural killer cells
    • Jewett, A., and Bonavida, B. Interferon-α activates cytotoxic function but inhibits interleukin-2-mediated proliferation and tumor necrosis factor-α secretion by immature human natural killer cells. J. Clin. Immunol., 15: 35-44, 1995.
    • (1995) J. Clin. Immunol. , vol.15 , pp. 35-44
    • Jewett, A.1    Bonavida, B.2
  • 68
    • 0022529254 scopus 로고
    • Binding of human α-interferons to natural killer cells
    • Langer, J. A., Ortaldo, J. R., and Pestka, S. Binding of human α-interferons to natural killer cells. J. Interferon Res., 6: 97-105, 1986.
    • (1986) J. Interferon Res. , vol.6 , pp. 97-105
    • Langer, J.A.1    Ortaldo, J.R.2    Pestka, S.3
  • 69
    • 0027058741 scopus 로고
    • A comparison of interferon-Con1 with natural recombinant interferons-α: Antiviral, antiproliferative, and natural killer-inducing activities
    • Ozes, O. N., Reiter, Z., and Klein, S. A comparison of interferon-Con1 with natural recombinant interferons-α: antiviral, antiproliferative, and natural killer-inducing activities. J. Interferon Res., 12: 55-59, 1992.
    • (1992) J. Interferon Res. , vol.12 , pp. 55-59
    • Ozes, O.N.1    Reiter, Z.2    Klein, S.3
  • 71
    • 0021254377 scopus 로고
    • Comparative in vivo and in vitro activation of human natural killer cells by two recombinant α interferons differing in antiviral activity
    • Edwards, B. S., Hawkins, M. J., and Borden, E. C. Comparative in vivo and in vitro activation of human natural killer cells by two recombinant α interferons differing in antiviral activity. Cancer Res., 44: 3135-3139, 1984.
    • (1984) Cancer Res. , vol.44 , pp. 3135-3139
    • Edwards, B.S.1    Hawkins, M.J.2    Borden, E.C.3
  • 73
    • 0019863205 scopus 로고
    • Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro
    • Dinarello, C. A., and Bernheim, H. A. Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro. J. Neurochem., 37: 702-708, 1981.
    • (1981) J. Neurochem. , vol.37 , pp. 702-708
    • Dinarello, C.A.1    Bernheim, H.A.2
  • 74
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello, C. A. Biologic basis for interleukin-1 in disease. Blood, 87: 2095-2147, 1996.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 75
    • 0024394325 scopus 로고
    • Interferons as inhibitors of interleukin 1-induced interleukin 1 synthesis
    • Schindler, R., Ghezzi, P., and Dinarello, C. A. Interferons as inhibitors of interleukin 1-induced interleukin 1 synthesis. Lymphokine Res., 8: 275-280, 1989.
    • (1989) Lymphokine Res. , vol.8 , pp. 275-280
    • Schindler, R.1    Ghezzi, P.2    Dinarello, C.A.3
  • 76
    • 0023719001 scopus 로고
    • IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-γ
    • Ghezzi, P., and Dinarello, C. A. IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-γ. J. Immunol., 140: 4238-4244, 1988.
    • (1988) J. Immunol. , vol.140 , pp. 4238-4244
    • Ghezzi, P.1    Dinarello, C.A.2
  • 77
    • 0025707532 scopus 로고
    • IL-1 induces IL-1, IV. IFN-γ suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1
    • Schindler, R., Ghezzi, P., and Dinarello, C. A. IL-1 induces IL-1, IV. IFN-γ suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1. J. Immunol., 144: 2216-2222, 1990.
    • (1990) J. Immunol. , vol.144 , pp. 2216-2222
    • Schindler, R.1    Ghezzi, P.2    Dinarello, C.A.3
  • 78
    • 0024535030 scopus 로고
    • A method for removing interleukin-1- and tumor necrosis factor-inducing substances from bacterial cultures by ultrafiltration with polysulfone
    • Schindler, R., and Dinarello, C. A. A method for removing interleukin-1- and tumor necrosis factor-inducing substances from bacterial cultures by ultrafiltration with polysulfone. J. Immunol. Methods, 116: 159-165, 1989.
    • (1989) J. Immunol. Methods , vol.116 , pp. 159-165
    • Schindler, R.1    Dinarello, C.A.2
  • 79
    • 0025317843 scopus 로고
    • Ultrafiltration to remove endotoxins and other cytokine-inducing materials from tissue culture media and parenteral fluids
    • Schindler, R., and Dinarello, C. A. Ultrafiltration to remove endotoxins and other cytokine-inducing materials from tissue culture media and parenteral fluids. Biotechniques, 8: 408-413, 1990.
    • (1990) Biotechniques , vol.8 , pp. 408-413
    • Schindler, R.1    Dinarello, C.A.2
  • 80
    • 0023201153 scopus 로고
    • Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro
    • Dinarello, C. A., Ikejima, T., Warner, S. J., Orencole, S. F., Lonnemann, G., Cannon, J. G., and Libby, P. Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro. J. Immunol., 139: 1902-1910, 1987.
    • (1987) J. Immunol. , vol.139 , pp. 1902-1910
    • Dinarello, C.A.1    Ikejima, T.2    Warner, S.J.3    Orencole, S.F.4    Lonnemann, G.5    Cannon, J.G.6    Libby, P.7
  • 81
    • 0025302145 scopus 로고
    • Dissociation between interleukin-1β mRNA and protein synthesis in human peripheral blood mononuclear cells
    • Schindler, R., Clark, B. D., and Dinarello, C. A. Dissociation between interleukin-1β mRNA and protein synthesis in human peripheral blood mononuclear cells. J. Biol. Chem., 265: 10232-10237, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10232-10237
    • Schindler, R.1    Clark, B.D.2    Dinarello, C.A.3
  • 82
    • 0023230528 scopus 로고
    • Interleukin-1 induces interleukin-1. II. Interleukin-1 induces production of interleukin-1 by adult human vascular endothelial cells in vitro
    • Warner, S. J. C., Auger, K. R., and Libby, P. Interleukin-1 induces interleukin-1. II. Interleukin-1 induces production of interleukin-1 by adult human vascular endothelial cells in vitro. J. Immunol., 139: 1911-1917, 1987.
    • (1987) J. Immunol. , vol.139 , pp. 1911-1917
    • Warner, S.J.C.1    Auger, K.R.2    Libby, P.3
  • 83
    • 0023268575 scopus 로고
    • Ultrafiltration to reject human interleukin-1-inducing substances derived from bacterial cultures
    • Dinarello, C. A., Lonnemann, G., Maxwell, R., and Shaldon, S. Ultrafiltration to reject human interleukin-1-inducing substances derived from bacterial cultures. J. Clin. Microbiol., 25: 1233-1238, 1987.
    • (1987) J. Clin. Microbiol. , vol.25 , pp. 1233-1238
    • Dinarello, C.A.1    Lonnemann, G.2    Maxwell, R.3    Shaldon, S.4
  • 84
    • 0025364667 scopus 로고
    • Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits
    • Ikejima, T., Okusawa, S., Ghezzi, P., van der Meer, J. W. M., and Dinarello, C. A. Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits. J. Infect. Dis., 162: 215-223, 1990.
    • (1990) J. Infect. Dis. , vol.162 , pp. 215-223
    • Ikejima, T.1    Okusawa, S.2    Ghezzi, P.3    Van Der Meer, J.W.M.4    Dinarello, C.A.5
  • 85
    • 0027965614 scopus 로고
    • Transcriptional inhibition of the interleukin-8 gene by interferon is mediated by the NF-κB site
    • Oliveira, I. C., Mukaida, N., Matsushima, K., and Vilcek, J. Transcriptional inhibition of the interleukin-8 gene by interferon is mediated by the NF-κB site. Mol. Cell. Biol., 14: 5300-5308, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5300-5308
    • Oliveira, I.C.1    Mukaida, N.2    Matsushima, K.3    Vilcek, J.4
  • 86
    • 0028982799 scopus 로고
    • Interferon-α inhibits the murine cytomegalovirus immediate-early gene expression by down-regulating NF-κB activity
    • Gribaudo, G., Ravaglia, S., Gaboli, M., Gariglio, M., Cavallo, R., and Landolfo, S. Interferon-α inhibits the murine cytomegalovirus immediate-early gene expression by down-regulating NF-κB activity. Virology, 211: 251-260, 1995.
    • (1995) Virology , vol.211 , pp. 251-260
    • Gribaudo, G.1    Ravaglia, S.2    Gaboli, M.3    Gariglio, M.4    Cavallo, R.5    Landolfo, S.6
  • 87
    • 0031889797 scopus 로고    scopus 로고
    • A perspective on the clinical effectiveness and tolerance of interferon-α
    • Borden, E. C., and Parkinson, D. A perspective on the clinical effectiveness and tolerance of interferon-α. Semin. Oncol., 25: 3-8, 1998.
    • (1998) Semin. Oncol. , vol.25 , pp. 3-8
    • Borden, E.C.1    Parkinson, D.2
  • 89
    • 0031915601 scopus 로고    scopus 로고
    • Safety profile of interferon-α therapy
    • Weiss, K. Safety profile of interferon-α therapy. Semin. Oncol., 25: 9-13, 1998.
    • (1998) Semin. Oncol. , vol.25 , pp. 9-13
    • Weiss, K.1
  • 90
    • 0031892756 scopus 로고    scopus 로고
    • Cytokines and anorexia: A brief overview
    • Plata-Salaman, C. R. Cytokines and anorexia: a brief overview. Semin. Oncol., 25: 64-72, 1998.
    • (1998) Semin. Oncol. , vol.25 , pp. 64-72
    • Plata-Salaman, C.R.1
  • 91
    • 0031889892 scopus 로고    scopus 로고
    • Fatigue: Definitions, mechanisms, and paradigms for study
    • Dalakas, M. C., Mock, V., and Hawkins, M. J. Fatigue: definitions, mechanisms, and paradigms for study. Semin. Oncol., 25: 48-53, 1998.
    • (1998) Semin. Oncol. , vol.25 , pp. 48-53
    • Dalakas, M.C.1    Mock, V.2    Hawkins, M.J.3
  • 92
    • 0031939896 scopus 로고    scopus 로고
    • Endocrine-mediated mechanisms of fatigue during treatment with interferon-α
    • Jones, T. H., Wadler, S., and Hupart, K. H. Endocrine-mediated mechanisms of fatigue during treatment with interferon-α. Semin. Oncol., 25: 54-63, 1998.
    • (1998) Semin. Oncol. , vol.25 , pp. 54-63
    • Jones, T.H.1    Wadler, S.2    Hupart, K.H.3
  • 93
    • 0031913930 scopus 로고    scopus 로고
    • Cytokines and brain function: Relevance to interferon-α-induced mood and cognitive changes
    • Licinio, J., Kling, M. A., and Hauser, P. Cytokines and brain function: relevance to interferon-α-induced mood and cognitive changes. Semin. Oncol., 25: 30-38, 1998.
    • (1998) Semin. Oncol. , vol.25 , pp. 30-38
    • Licinio, J.1    Kling, M.A.2    Hauser, P.3
  • 95
    • 0031952966 scopus 로고    scopus 로고
    • The effects of interferon-α on the production and action of other cytokines
    • Taylor, J. L., and Grossberg, S. E. The effects of interferon-α on the production and action of other cytokines. Semin. Oncol., 25: 23-29, 1998.
    • (1998) Semin. Oncol. , vol.25 , pp. 23-29
    • Taylor, J.L.1    Grossberg, S.E.2
  • 96
    • 0028246553 scopus 로고
    • Development of neutralizing and binding antibodies to interferon (IFN) in patients undergoing IFN therapy
    • Antonelli, G. Development of neutralizing and binding antibodies to interferon (IFN) in patients undergoing IFN therapy. Antiviral Res., 24: 235-244, 1994.
    • (1994) Antiviral Res. , vol.24 , pp. 235-244
    • Antonelli, G.1
  • 97
    • 0030742739 scopus 로고    scopus 로고
    • In vivo development of antibody to interferons: An update to 1996
    • Antonelli, G. In vivo development of antibody to interferons: an update to 1996. J. Interferon Cytokine Res., 17 (Suppl. 1): S39-S46, 1997.
    • (1997) J. Interferon Cytokine Res. , vol.17 , Issue.1 SUPPL.
    • Antonelli, G.1
  • 98
    • 0029558511 scopus 로고
    • Immune-mediated side effects of cytokines in humans
    • Vial, T., and Descotes, J. Immune-mediated side effects of cytokines in humans. Toxicology, 105: 31-57, 1995.
    • (1995) Toxicology , vol.105 , pp. 31-57
    • Vial, T.1    Descotes, J.2
  • 99
    • 0030936629 scopus 로고    scopus 로고
    • Antibodies to interferon-α in treated cancer patients: Incidence and significance
    • McKenna, R. M., and Oberg, K. E. Antibodies to interferon-α in treated cancer patients: incidence and significance. J. Interferon Cytokine Res., 17: 141-143, 1997.
    • (1997) J. Interferon Cytokine Res. , vol.17 , pp. 141-143
    • McKenna, R.M.1    Oberg, K.E.2
  • 100
    • 0030742535 scopus 로고    scopus 로고
    • Natural autoantibodies to interferons
    • Meager, A. Natural autoantibodies to interferons. J. Interferon Cytokine Res., 17 (Suppl. 1): S51-S53, 1997.
    • (1997) J. Interferon Cytokine Res. , vol.17 , Issue.1 SUPPL.
    • Meager, A.1
  • 101
    • 0030838371 scopus 로고    scopus 로고
    • Assays for antibodies to human interferon-α: The need for standardization
    • Schellekens, H., Ryff, J. C., and van der Meide, P. H. Assays for antibodies to human interferon-α: the need for standardization. J. Interferon Cytokine Res., 17 (Suppl. 1): S5-S8, 1997.
    • (1997) J. Interferon Cytokine Res. , vol.17 , Issue.1 SUPPL.
    • Schellekens, H.1    Ryff, J.C.2    Van Der Meide, P.H.3
  • 102
    • 0025759062 scopus 로고
    • Neutralizing antibodies to interferon-α: Relative frequency in patients treated with different interferon preparations
    • Antonelli, G., Currenti, M., Turriziani, O., and Dianzani, F. Neutralizing antibodies to interferon-α: relative frequency in patients treated with different interferon preparations. J. Infect. Dis., 163: 882-885, 1991.
    • (1991) J. Infect. Dis. , vol.163 , pp. 882-885
    • Antonelli, G.1    Currenti, M.2    Turriziani, O.3    Dianzani, F.4
  • 103
    • 0026547361 scopus 로고
    • Relative frequency of nonneutralizing antibodies to interferon (IFN) in hepatitis patients treated with different IFN-α preparations
    • Antonelli, G., Currenti, M., Turriziani, O., Riva, E., and Dianzani, F. Relative frequency of nonneutralizing antibodies to interferon (IFN) in hepatitis patients treated with different IFN-α preparations. J. Infect. Dis., 165: 593-594, 1992.
    • (1992) J. Infect. Dis. , vol.165 , pp. 593-594
    • Antonelli, G.1    Currenti, M.2    Turriziani, O.3    Riva, E.4    Dianzani, F.5
  • 106
    • 0025940808 scopus 로고
    • Antibodies in patients with recurrent respiratory papillomatosis treated with lymphoblastoid interferon
    • Thurmond, L. M., Brand, C. M., Leventhal, B. G., Finter, N. B., and Johnston, J. M. Antibodies in patients with recurrent respiratory papillomatosis treated with lymphoblastoid interferon. J. Lab. Clin. Med., 118: 232-240, 1991.
    • (1991) J. Lab. Clin. Med. , vol.118 , pp. 232-240
    • Thurmond, L.M.1    Brand, C.M.2    Leventhal, B.G.3    Finter, N.B.4    Johnston, J.M.5
  • 107
    • 0025098971 scopus 로고
    • Incidence of response and long-term follow-up in patients with hairy cell leukemia treated with recombinant interferon α-2a
    • Berman, E., Heller, G., Kempin, S., Gee, T., Tran, L. L., and Clarkson, B. Incidence of response and long-term follow-up in patients with hairy cell leukemia treated with recombinant interferon α-2a. Blood, 75: 839-845, 1990.
    • (1990) Blood , vol.75 , pp. 839-845
    • Berman, E.1    Heller, G.2    Kempin, S.3    Gee, T.4    Tran, L.L.5    Clarkson, B.6
  • 108
    • 0028219410 scopus 로고
    • Interferon antibodies in patients with chronic hepatitic C virus infection treated with recombinant interferon α-2a
    • Amst.
    • Bonetti, P., Diodati, G., Drago, C., Casarin, C., Scaccabarozzi, S., Realdi, G., Ruol, A., and Alberti, A. Interferon antibodies in patients with chronic hepatitic C virus infection treated with recombinant interferon α-2a. J. Hepatol. (Amst.), 20: 416-420, 1994.
    • (1994) J. Hepatol. , vol.20 , pp. 416-420
    • Bonetti, P.1    Diodati, G.2    Drago, C.3    Casarin, C.4    Scaccabarozzi, S.5    Realdi, G.6    Ruol, A.7    Alberti, A.8
  • 109
    • 0027412933 scopus 로고
    • Antibodies developing against a single recombinant interferon protein may neutralize many other interferon-α subtypes
    • Brand, C. M., Leadbeater, L., Bellati, G., Marotta, F., and Ideo, G. Antibodies developing against a single recombinant interferon protein may neutralize many other interferon-α subtypes. J. Interferon Res., 13: 121-125, 1993.
    • (1993) J. Interferon Res. , vol.13 , pp. 121-125
    • Brand, C.M.1    Leadbeater, L.2    Bellati, G.3    Marotta, F.4    Ideo, G.5
  • 111
    • 0024243915 scopus 로고
    • Recombinant interferon α-2a in metastatic renal cell carcinoma: Assessment of antitumor activity and anti-interferon antibody formation
    • Figlin, R. A., deKernion, J. B., Mukamel, E., Palleroni, A. V., Itri, L. M., and Sarna, G. P. Recombinant interferon α-2a in metastatic renal cell carcinoma: assessment of antitumor activity and anti-interferon antibody formation. J. Clin. Oncol., 6: 1604-1610, 1988.
    • (1988) J. Clin. Oncol. , vol.6 , pp. 1604-1610
    • Figlin, R.A.1    DeKernion, J.B.2    Mukamel, E.3    Palleroni, A.V.4    Itri, L.M.5    Sarna, G.P.6
  • 112
    • 0025064525 scopus 로고
    • Interferon-induced enhancement of 2′,5′-oligoadenylate synthetase in mid-gut carcinoid tumours
    • Grander, D., Oberg, K., Lundqvist, M. L., Janson, E. T., Eriksson, B., and Einhorn, S. Interferon-induced enhancement of 2′,5′-oligoadenylate synthetase in mid-gut carcinoid tumours. Lancet, 336: 337-340, 1990.
    • (1990) Lancet , vol.336 , pp. 337-340
    • Grander, D.1    Oberg, K.2    Lundqvist, M.L.3    Janson, E.T.4    Eriksson, B.5    Einhorn, S.6
  • 113
    • 0023296168 scopus 로고
    • Incidence and clinical significance of neutralizing antibodies in patients receiving recombinant interferon α-2a by intra-muscular injection
    • Phila.
    • Itri, L. M., Campion, M., Dennin, R. A., Palleroni, A. V., Gutterman, J. U., Groopman, J. E., and Trown, P. W. Incidence and clinical significance of neutralizing antibodies in patients receiving recombinant interferon α-2a by intra-muscular injection. Cancer (Phila.), 59: 668-674, 1987.
    • (1987) Cancer , vol.59 , pp. 668-674
    • Itri, L.M.1    Campion, M.2    Dennin, R.A.3    Palleroni, A.V.4    Gutterman, J.U.5    Groopman, J.E.6    Trown, P.W.7
  • 114
    • 0006591867 scopus 로고
    • Incidence, neutralizing activity, and clinical significance of interferon antibodies in chronic hepatitis B patients receiving recombinant α-interferons
    • F. B. Hollinger, S. M. Lemon, and H. Margolis (eds.), Baltimore, MD: Williams & Wilkins
    • Lok, A. S. F., and Lai, C. L. Incidence, neutralizing activity, and clinical significance of interferon antibodies in chronic hepatitis B patients receiving recombinant α-interferons. In: F. B. Hollinger, S. M. Lemon, and H. Margolis (eds.), Viral Hepatitis and Liver Disease, 7th ed., pp. 643-644. Baltimore, MD: Williams & Wilkins, 1991.
    • (1991) Viral Hepatitis and Liver Disease, 7th Ed. , pp. 643-644
    • Lok, A.S.F.1    Lai, C.L.2
  • 115
    • 0025607230 scopus 로고
    • Interferon antibodies may negate the antiviral effects of recombinant α-interferon treatment in patients with chronic hepatitis B virus infection
    • Lok, A. S. F., Lai, C. L., and Leung, E. K. Interferon antibodies may negate the antiviral effects of recombinant α-interferon treatment in patients with chronic hepatitis B virus infection. Hepatology, 12: 1266-1270, 1990.
    • (1990) Hepatology , vol.12 , pp. 1266-1270
    • Lok, A.S.F.1    Lai, C.L.2    Leung, E.K.3
  • 117
    • 0024563550 scopus 로고
    • Interferon antibodies in patients with chronic HBV infection treated with recombinant interferon
    • Amst.
    • Porres, J. C., Carreno, V., Ruiz, M., Marron, J. A., and Bartolome, J. Interferon antibodies in patients with chronic HBV infection treated with recombinant interferon. J. Hepatol. (Amst.), 8: 351-357, 1989.
    • (1989) J. Hepatol. , vol.8 , pp. 351-357
    • Porres, J.C.1    Carreno, V.2    Ruiz, M.3    Marron, J.A.4    Bartolome, J.5
  • 118
    • 0027409257 scopus 로고
    • Interferon-α antibodies in patients with renal cell carcinoma treated with recombinant interferon-α-2a in an adjuvant multicenter trial. The Delta-P Study Group
    • Phila.
    • Prummer, O. Interferon-α antibodies in patients with renal cell carcinoma treated with recombinant interferon-α-2a in an adjuvant multicenter trial. The Delta-P Study Group. Cancer (Phila.), 71: 1828-1834, 1993.
    • (1993) Cancer , vol.71 , pp. 1828-1834
    • Prummer, O.1
  • 119
    • 0022359745 scopus 로고
    • Antitumor activity of recombinant-derived interferon α in metastatic renal cell carcinoma
    • Quesada, J. R., Rios, A., Swanson, D., Trown, P., and Gutterman, J. U. Antitumor activity of recombinant-derived interferon α in metastatic renal cell carcinoma. J. Clin. Oncol., 3: 1522-1528, 1985.
    • (1985) J. Clin. Oncol. , vol.3 , pp. 1522-1528
    • Quesada, J.R.1    Rios, A.2    Swanson, D.3    Trown, P.4    Gutterman, J.U.5
  • 120
    • 0026785029 scopus 로고
    • Characterization of anti-interferon-α antibodies appearing during recombinant interferon-α-2a treatment
    • Ronnblom, L. E., Janson, E. T., Perers, A., Oberg, K. E., and Alm, G. V. Characterization of anti-interferon-α antibodies appearing during recombinant interferon-α-2a treatment. Clin. Exp. Immunol., 89: 330-335, 1992.
    • (1992) Clin. Exp. Immunol. , vol.89 , pp. 330-335
    • Ronnblom, L.E.1    Janson, E.T.2    Perers, A.3    Oberg, K.E.4    Alm, G.V.5
  • 121
    • 8944249778 scopus 로고    scopus 로고
    • Neutralizing anti-interferon-α antibodies and response to treatment in patients with Ph+ chronic myeloid leukaemia sequentially treated with recombinant (α 2a) and lymphoblastoid interferon-α
    • Russo, D., Candoni, A., Zuffa, E., Minisini, R., Silvestri, F., Fanin, R., Zaja, F., Martinelli, G., Tura, S., Botta, G., and Baccarani, M. Neutralizing anti-interferon-α antibodies and response to treatment in patients with Ph+ chronic myeloid leukaemia sequentially treated with recombinant (α 2a) and lymphoblastoid interferon-α. Br. J. Haematol., 94: 300-305, 1996.
    • (1996) Br. J. Haematol. , vol.94 , pp. 300-305
    • Russo, D.1    Candoni, A.2    Zuffa, E.3    Minisini, R.4    Silvestri, F.5    Fanin, R.6    Zaja, F.7    Martinelli, G.8    Tura, S.9    Botta, G.10    Baccarani, M.11
  • 122
    • 0027181276 scopus 로고
    • Treatment of chronic myeloid leukemia with interferon α (Roferon): Results of the Israeli Study Group on CML
    • Shtalrid, M., Lugassy, G., Rosensaft, J., and Berrebi, A. Treatment of chronic myeloid leukemia with interferon α (Roferon): results of the Israeli Study Group on CML. Leuk. Lymphoma, 11 (Suppl. 1): 193-197, 1993.
    • (1993) Leuk. Lymphoma , vol.11 , Issue.1 SUPPL. , pp. 193-197
    • Shtalrid, M.1    Lugassy, G.2    Rosensaft, J.3    Berrebi, A.4
  • 123
    • 0023893064 scopus 로고
    • Resistance to recombinant interferon α-2a in hairy-cell leukemia associated with neutralizing anti-interferon antibodies
    • Steis, R. G., Smith, J. W., II, Urba, W. J., Clark, J. W., Itri, L. M., Evans, L. M., Schoenberger, C., and Longo, D. L. Resistance to recombinant interferon α-2a in hairy-cell leukemia associated with neutralizing anti-interferon antibodies. N. Engl. J. Med., 318: 1409-1413, 1988.
    • (1988) N. Engl. J. Med. , vol.318 , pp. 1409-1413
    • Steis, R.G.1    Smith II, J.W.2    Urba, W.J.3    Clark, J.W.4    Itri, L.M.5    Evans, L.M.6    Schoenberger, C.7    Longo, D.L.8
  • 125
    • 0027965405 scopus 로고
    • Neutralising antibodies in patients with multiple myeloma receiving maintenance therapy with interferon α 2b
    • Bell, J. B., Barfoot, R., Iveson, T., Powles, R. L., and Millar, B. C. Neutralising antibodies in patients with multiple myeloma receiving maintenance therapy with interferon α 2b. Br. J. Cancer, 70: 646-651, 1994.
    • (1994) Br. J. Cancer , vol.70 , pp. 646-651
    • Bell, J.B.1    Barfoot, R.2    Iveson, T.3    Powles, R.L.4    Millar, B.C.5
  • 127
    • 0024730839 scopus 로고
    • Low incidence of neutralizing antibody formation to interferon-α 2b in human recipients
    • Dianzani, F., Antonelli, G., Amicucci, P., Cefaro, A., and Pintus, C. Low incidence of neutralizing antibody formation to interferon-α 2b in human recipients. J. Interferon Res., 9 (Suppl. 1): S33-S36, 1989.
    • (1989) J. Interferon Res. , vol.9 , Issue.1 SUPPL.
    • Dianzani, F.1    Antonelli, G.2    Amicucci, P.3    Cefaro, A.4    Pintus, C.5
  • 132
    • 0024589903 scopus 로고
    • Long-term interferon therapy for thrombocytosis in myeloproliferative diseases
    • Gisslinger, H., Ludwig, H., Linkesch, W., Chott, A., Fritz, E., and Radaszkiewicz, T. Long-term interferon therapy for thrombocytosis in myeloproliferative diseases. Lancet, i: 634-637, 1989.
    • (1989) Lancet , vol.1 , pp. 634-637
    • Gisslinger, H.1    Ludwig, H.2    Linkesch, W.3    Chott, A.4    Fritz, E.5    Radaszkiewicz, T.6
  • 134
    • 0030803840 scopus 로고    scopus 로고
    • Interferon immunogenicity: Technical evaluation of interferon-α2a
    • Hochuli, E. Interferon immunogenicity: technical evaluation of interferon-α2a. J. Interferon Cytokine Res., 17 (Suppl. 1): S15-S21, 1997.
    • (1997) J. Interferon Cytokine Res. , vol.17 , Issue.1 SUPPL.
    • Hochuli, E.1
  • 135
    • 0030754581 scopus 로고    scopus 로고
    • Clinical investigation of the immunogenicity of interferon-α2a
    • Ryff, J. C. Clinical investigation of the immunogenicity of interferon-α2a. J. Interferon Cytokine Res., 17 (Suppl. 1): S29-S33, 1997.
    • (1997) J. Interferon Cytokine Res. , vol.17 , Issue.1 SUPPL.
    • Ryff, J.C.1
  • 136
    • 0002229292 scopus 로고    scopus 로고
    • Interferons
    • J. F. Holland, E. Frei III, J. R. Bast, D. W. Kufe, D. L. Morton, and R. R. Weichselbaum (eds.), Baltimore, MD: Williams & Wilkins
    • Borden, E. C. Interferons. In: J. F. Holland, E. Frei III, J. R. Bast, D. W. Kufe, D. L. Morton, and R. R. Weichselbaum (eds.), Cancer Medicine, pp. 1199-1212. Baltimore, MD: Williams & Wilkins, 1997.
    • (1997) Cancer Medicine , pp. 1199-1212
    • Borden, E.C.1
  • 137
    • 0028117299 scopus 로고
    • Cytokine therapeutics: Lessons form interferon α
    • Gutterman, J. U. Cytokine therapeutics: lessons form interferon α. Proc. Natl. Acad. Sci. USA, 91: 1198-1205, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1198-1205
    • Gutterman, J.U.1
  • 139
    • 0026316478 scopus 로고
    • A randomized comparison of two doses of human lymphoblastoid interferon-α in hairy cell leukemia. Wellcome HCL Study Group
    • Smalley, R. V., Anderson, S. A., Tuttle, R. L., Connors, J., Thurmond, L. M., Huang, A., Castle, K., Magers, C., and Whisnant, J. K. A randomized comparison of two doses of human lymphoblastoid interferon-α in hairy cell leukemia. Wellcome HCL Study Group. Blood, 78: 3133-3141, 1991.
    • (1991) Blood , vol.78 , pp. 3133-3141
    • Smalley, R.V.1    Anderson, S.A.2    Tuttle, R.L.3    Connors, J.4    Thurmond, L.M.5    Huang, A.6    Castle, K.7    Magers, C.8    Whisnant, J.K.9
  • 140
    • 0023194027 scopus 로고
    • Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. VI. Adjuvant therapy after surgery in the inhibition of liver and spleen metastases
    • Gresser, I., Maury, C., and Belardelli, F. Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. VI. Adjuvant therapy after surgery in the inhibition of liver and spleen metastases. Int. J. Cancer, 39: 789-792, 1987.
    • (1987) Int. J. Cancer , vol.39 , pp. 789-792
    • Gresser, I.1    Maury, C.2    Belardelli, F.3
  • 141
    • 0023940143 scopus 로고
    • Rationale for recombinant human interferon-γ adjuvant immunotherapy for cancer
    • Jaffe, H. S., and Herberman, R. B. Rationale for recombinant human interferon-γ adjuvant immunotherapy for cancer. J. Natl. Cancer Inst., 80: 616-618, 1988.
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 616-618
    • Jaffe, H.S.1    Herberman, R.B.2
  • 143
    • 0022547088 scopus 로고
    • Treatment of metastatic malignant melanoma with recombinant interferon α 2
    • Robinson, W. A., Mughal, T. I., Thomas, M. R., Johnson, M., and Spiegel, R. J. Treatment of metastatic malignant melanoma with recombinant interferon α 2. Immunobiology, 172: 275-282, 1986.
    • (1986) Immunobiology , vol.172 , pp. 275-282
    • Robinson, W.A.1    Mughal, T.I.2    Thomas, M.R.3    Johnson, M.4    Spiegel, R.J.5
  • 144
    • 0002262637 scopus 로고
    • Interferons. Melanoma
    • V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Philadelphia, PA: J. B. Lippincott Co.
    • Kirkwood, J. M. Interferons. Melanoma. In: V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Biologic Therapy of Cancer, 2nd ed., pp. 388-411. Philadelphia, PA: J. B. Lippincott Co., 1995.
    • (1995) Biologic Therapy of Cancer, 2nd Ed. , pp. 388-411
    • Kirkwood, J.M.1
  • 145
    • 0030030347 scopus 로고    scopus 로고
    • Interferon α-2b adjuvant therapy of high risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group trial est. 1684
    • Kirkwood, J. M., Strawderman, M. H., Ernstoff, M. S., Smith, T. J., Borden, E. C., and Blum, R. H. Interferon α-2b adjuvant therapy of high risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group trial est. 1684. J. Clin. Oncol., 14: 7-17, 1996.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 7-17
    • Kirkwood, J.M.1    Strawderman, M.H.2    Ernstoff, M.S.3    Smith, T.J.4    Borden, E.C.5    Blum, R.H.6
  • 146
    • 0028606048 scopus 로고
    • Innovative treatment strategies for non-Hodgkin's lymphoma and multiple myeloma
    • Borden, E. C. Innovative treatment strategies for non-Hodgkin's lymphoma and multiple myeloma. Semin. Oncol., 21 (Suppl. 14): 14-22, 1994.
    • (1994) Semin. Oncol. , vol.21 , Issue.14 SUPPL. , pp. 14-22
    • Borden, E.C.1
  • 149
    • 0023270894 scopus 로고
    • Recombinant interferon α-2a, an active agent in advanced cutaneous T-cell lymphomas
    • Bunn, P. A., Jr. Recombinant interferon α-2a, an active agent in advanced cutaneous T-cell lymphomas. Int. J. Cancer, 1 (Suppl.): 9-13, 1987.
    • (1987) Int. J. Cancer , vol.1 , Issue.SUPPL. , pp. 9-13
    • Bunn Jr., P.A.1
  • 150
    • 0022189515 scopus 로고
    • Interferon in the treatment of multiple myeloma and the non-Hodgkin's lymphomas
    • Wagstaff, J., Scarffe, J. H., and Crowther, D. Interferon in the treatment of multiple myeloma and the non-Hodgkin's lymphomas. Cancer Treat. Rev., 12B: 39-44, 1985.
    • (1985) Cancer Treat. Rev. , vol.12 B , pp. 39-44
    • Wagstaff, J.1    Scarffe, J.H.2    Crowther, D.3
  • 154
    • 0024241168 scopus 로고
    • Biotherapy of chronic myelogenous leukemia with IFN
    • Ozer, H. Biotherapy of chronic myelogenous leukemia with IFN. Semin. Oncol., 15 (Suppl. 5): 14-20, 1988.
    • (1988) Semin. Oncol. , vol.15 , Issue.5 SUPPL. , pp. 14-20
    • Ozer, H.1
  • 155
    • 0028577655 scopus 로고
    • Use of interferons in the treatment of chronic myelogenous leukemia
    • Talpaz, M. Use of interferons in the treatment of chronic myelogenous leukemia. Semin. Oncol., 21 (Suppl. 14): 3-7, 1994.
    • (1994) Semin. Oncol. , vol.21 , Issue.14 SUPPL. , pp. 3-7
    • Talpaz, M.1
  • 157
    • 23444462074 scopus 로고
    • Interferon α-2a as compared with conventional chemotherapy for the treatment of chronic myeloid leukemia
    • The Italian Cooperative Study Group on Chronic Myeloid Leukemia. Interferon α-2a as compared with conventional chemotherapy for the treatment of chronic myeloid leukemia. N. Engl. J. Med., 330: 820-825, 1994.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 820-825
  • 159
    • 0030983633 scopus 로고    scopus 로고
    • Increasing effectiveness of Interferon-α for malignancies
    • Lindner, D. J., Kalvakolanu, D. V., and Borden, E. C. Increasing effectiveness of Interferon-α for malignancies. Semin. Oncol., 24 (Suppl. 9): S9-99-S9-104, 1997.
    • (1997) Semin. Oncol. , vol.24 , Issue.9 SUPPL.
    • Lindner, D.J.1    Kalvakolanu, D.V.2    Borden, E.C.3
  • 160
    • 0025293764 scopus 로고
    • Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: A review
    • Wadler, S., and Schwartz, E. L. Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: a review. Cancer Res., 50: 3473-3486, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 3473-3486
    • Wadler, S.1    Schwartz, E.L.2
  • 161
    • 0032519590 scopus 로고    scopus 로고
    • Inhibition of basic fibroblast growth factor expression, angiogenesis, and growth of human bladder carcinoma in mice by systemic interferon-α administration
    • Dinney, C. P., Bielenberg, D. R., Perrotte, P., Reigh, R., Eve, B. Y., Bucana, C. D., and Fidler, I. J. Inhibition of basic fibroblast growth factor expression, angiogenesis, and growth of human bladder carcinoma in mice by systemic interferon-α administration. Cancer Res., 58: 808-814, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 808-814
    • Dinney, C.P.1    Bielenberg, D.R.2    Perrotte, P.3    Reigh, R.4    Eve, B.Y.5    Bucana, C.D.6    Fidler, I.J.7
  • 162
    • 0023160237 scopus 로고
    • Inhibition of angiogenesis by interferons: Effects on tumor- and lymphocyte-induced vascular responses
    • Sidky, Y. A., and Borden, E. C. Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses. Cancer Res., 47: 5155-5161, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 5155-5161
    • Sidky, Y.A.1    Borden, E.C.2
  • 164
    • 0029739081 scopus 로고    scopus 로고
    • Quality-of-life-adjusted survival analysis of interferon α-2b adjuvant treatment of high-risk resected cutaneous melanoma: An Eastern Cooperative Oncology Group Study
    • Cole, B. F., Gelber, R. D., Kirkwood, J. M., Goldhirsch, A., Barylak, E., and Borden, E. Quality-of-life-adjusted survival analysis of interferon α-2b adjuvant treatment of high-risk resected cutaneous melanoma: an Eastern Cooperative Oncology Group Study. J. Clin. Oncol., 14: 2666-2673, 1996.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 2666-2673
    • Cole, B.F.1    Gelber, R.D.2    Kirkwood, J.M.3    Goldhirsch, A.4    Barylak, E.5    Borden, E.6
  • 165
    • 0030912852 scopus 로고    scopus 로고
    • Economic analysis of adjuvant interferon α-2b in high-risk melanoma based on projections from Eastern Cooperative Oncology Group 1684
    • Hillner, B. E., Kirkwood, J. M., Atkins, M. B., Johnson, E. R., and Smith, T. J. Economic analysis of adjuvant interferon α-2b in high-risk melanoma based on projections from Eastern Cooperative Oncology Group 1684. J. Clin. Oncol., 15: 2351-2358, 1997.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 2351-2358
    • Hillner, B.E.1    Kirkwood, J.M.2    Atkins, M.B.3    Johnson, E.R.4    Smith, T.J.5
  • 166
    • 0030757470 scopus 로고    scopus 로고
    • Cost-effectiveness of interferon α in chronic myelogenous leukemia
    • Liberato, N. L., Quaglini, S., and Barosi, G. Cost-effectiveness of interferon α in chronic myelogenous leukemia. J. Clin. Oncol., 15: 2673-2682, 1997.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 2673-2682
    • Liberato, N.L.1    Quaglini, S.2    Barosi, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.