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Volumn 560, Issue , 2005, Pages 29-39

Genetic analysis of innate immunity: Identification and function of the TIR adapter proteins

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; DOUBLE STRANDED RNA; ENDOTOXIN; INTERFERON REGULATORY FACTOR 1; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; DIFFERENTIATION ANTIGEN; IMMUNOGLOBULIN RECEPTOR; INTERLEUKIN 1 RECEPTOR; MEMBRANE PROTEIN; MYD88 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TICAM1 PROTEIN, HUMAN; TIRAP PROTEIN, HUMAN; TRAM PROTEIN, ER, MAMMALIAN; VESICULAR TRANSPORT ADAPTOR PROTEIN;

EID: 20344364201     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/0-387-24180-9_4     Document Type: Conference Paper
Times cited : (36)

References (48)
  • 1
    • 0001371506 scopus 로고
    • High susceptibility of strain a mice to endotoxin and endotoxin-red blood cell mixtures
    • G. Heppner and D. W. Weiss, High susceptibility of strain A mice to endotoxin and endotoxin-red blood cell mixtures, J. Bacteriol. 90:696-703 (1965).
    • (1965) J. Bacteriol. , vol.90 , pp. 696-703
    • Heppner, G.1    Weiss, D.W.2
  • 2
    • 0015801660 scopus 로고
    • Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity
    • J. M. Chiller, B. J. Skidmore, D. C. Morrison, and W. O. Weigle, Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity, Proc. Natl. Acad. Sci. U. S. A. 70(7), 2129-2133 (1973).
    • (1973) Proc. Natl. Acad. Sci. U. S. A. , vol.70 , Issue.7 , pp. 2129-2133
    • Chiller, J.M.1    Skidmore, B.J.2    Morrison, D.C.3    Weigle, W.O.4
  • 3
    • 0016639224 scopus 로고
    • Immunologic properties of bacterial lipopolysaccharide (LPS): Correlation between the mitogenic, adjuvant, and immunogenic activities
    • B. J. Skidmore, J. M. Chiller, D. C. Morrison, and W. O. Weigle, Immunologic properties of bacterial lipopolysaccharide (LPS): correlation between the mitogenic, adjuvant, and immunogenic activities, J. Immunol. 114(2 pt 2), 770-775 (1975).
    • (1975) J. Immunol. , vol.114 , Issue.2 PART 2 , pp. 770-775
    • Skidmore, B.J.1    Chiller, J.M.2    Morrison, D.C.3    Weigle, W.O.4
  • 4
    • 0016801894 scopus 로고
    • Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS
    • B. J. Skidmore, D. C. Morrison, J. M. Chiller, and W. O. Weigle, Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS, J. Exp. Med. 142(6), 1488-1508 (1975).
    • (1975) J. Exp. Med. , vol.142 , Issue.6 , pp. 1488-1508
    • Skidmore, B.J.1    Morrison, D.C.2    Chiller, J.M.3    Weigle, W.O.4
  • 5
    • 0016881599 scopus 로고
    • Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS
    • B. J. Skidmore, J. M. Chiller, W. O. Weigle, R. Riblet, and J. Watson, Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS, J. Exp. Med. 143(1), 143-150 (1976).
    • (1976) J. Exp. Med. , vol.143 , Issue.1 , pp. 143-150
    • Skidmore, B.J.1    Chiller, J.M.2    Weigle, W.O.3    Riblet, R.4    Watson, J.5
  • 6
    • 0017359357 scopus 로고
    • Immunologic properties of bacterial lipopolysaccharide (LPS). IV. Cellular basis of the unresponsiveness of C3H/HeJ mouse spleen cells to LPS-induced mitogenesis
    • B. J. Skidmore, J. M. Chiller, and W. O. Weigle, Immunologic properties of bacterial lipopolysaccharide (LPS). IV. Cellular basis of the unresponsiveness of C3H/HeJ mouse spleen cells to LPS-induced mitogenesis, J. Immunol. 118(1), 274-281 (1977).
    • (1977) J. Immunol. , vol.118 , Issue.1 , pp. 274-281
    • Skidmore, B.J.1    Chiller, J.M.2    Weigle, W.O.3
  • 7
    • 0016294676 scopus 로고
    • Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides
    • J. Watson and R. Riblet, Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides, J. Exp. Med. 140(5), 1147-1161 (1974).
    • (1974) J. Exp. Med. , vol.140 , Issue.5 , pp. 1147-1161
    • Watson, J.1    Riblet, R.2
  • 8
    • 0018858071 scopus 로고
    • The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxin
    • S. M. Michalek, R. N. Moore, J. R. McGhee, D. L. Rosenstreich, and S. E. Mergenhagen, The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxin, J. Infec. Dis. 141:55-63 (1980).
    • (1980) J. Infec. Dis. , vol.141 , pp. 55-63
    • Michalek, S.M.1    Moore, R.N.2    McGhee, J.R.3    Rosenstreich, D.L.4    Mergenhagen, S.E.5
  • 9
    • 0019175872 scopus 로고
    • Control of natural resistance to Salmonella typhimurium and Leishmania donovani in mice by closely linked but distinct genetic loci
    • A. D. O'Brien, D. L. Rosenstreich, and B. A. Taylor, Control of natural resistance to Salmonella typhimurium and Leishmania donovani in mice by closely linked but distinct genetic loci, Nature 287(5781), 440-442 (1980).
    • (1980) Nature , vol.287 , Issue.5781 , pp. 440-442
    • O'Brien, A.D.1    Rosenstreich, D.L.2    Taylor, B.A.3
  • 12
    • 0021703558 scopus 로고
    • Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice
    • L. Hagberg, R. Hull, S. Hull, J. R. McGhee, S. M. Michalek, and C. Svanborg Eden, Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice, Infect. Immun. 46(3), 839-844 (1984).
    • (1984) Infect. Immun. , vol.46 , Issue.3 , pp. 839-844
    • Hagberg, L.1    Hull, R.2    Hull, S.3    McGhee, J.R.4    Michalek, S.M.5    Svanborg Eden, C.6
  • 15
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • B. Lemaitre, E. Nicolas, L. Michaut, J. M. Reichhart, and J. A. Hoffmann, The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults, Cell 86(6), 973-983 (1996).
    • (1996) Cell , vol.86 , Issue.6 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 16
    • 0037083557 scopus 로고    scopus 로고
    • Cutting edge: The toll pathway is required for resistance to gram-positive bacterial infections in Drosophila
    • S. Rutschmann, A. Kilinc, and D. Ferrandon, Cutting edge: the toll pathway is required for resistance to gram-positive bacterial infections in Drosophila, J. Immunol. 168(4), 1542-1546 (2002).
    • (2002) J. Immunol. , vol.168 , Issue.4 , pp. 1542-1546
    • Rutschmann, S.1    Kilinc, A.2    Ferrandon, D.3
  • 17
    • 0028685657 scopus 로고
    • Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1
    • N. Nomura, N. Miyajima, T. Sazuka, A. Tanaka, Y. Kawarabayasi, S. Sato, T. Nagase, N. Seki, K. Ishikawa, and S. Tabata, Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1, DNA Res. 1(1), 27-35 (1994).
    • (1994) DNA Res. , vol.1 , Issue.1 , pp. 27-35
    • Nomura, N.1    Miyajima, N.2    Sazuka, T.3    Tanaka, A.4    Kawarabayasi, Y.5    Sato, S.6    Nagase, T.7    Seki, N.8    Ishikawa, K.9    Tabata, S.10
  • 18
    • 0029867832 scopus 로고    scopus 로고
    • Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14
    • T. Taguchi, J. L. Mitcham, S. K. Dower, J. E. Sims, and J. R. Testa, Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14, Genom. 32(3), 486-488 (1996).
    • (1996) Genom. , vol.32 , Issue.3 , pp. 486-488
    • Taguchi, T.1    Mitcham, J.L.2    Dower, S.K.3    Sims, J.E.4    Testa, J.R.5
  • 19
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • O. Takeuchi, K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira, Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components, Immunity 11(4), 443-451 (1999).
    • (1999) Immunity , vol.11 , Issue.4 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5    Ogawa, T.6    Takeda, K.7    Akira, S.8
  • 20
    • 0038558249 scopus 로고    scopus 로고
    • Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2
    • B. N. Gantner, R. M. Simmons, S. J. Canavera, S. Akira, and D. M. Underhill, Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2, J. Exp. Med. 197(9), 1107-1117 (2003).
    • (2003) J. Exp. Med. , vol.197 , Issue.9 , pp. 1107-1117
    • Gantner, B.N.1    Simmons, R.M.2    Canavera, S.J.3    Akira, S.4    Underhill, D.M.5
  • 21
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • L. Alexopoulou, A. C. Holt, R. Medzhitov, and R. A. Flavell, Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3, Nature 413(6857), 732-738 (2001).
    • (2001) Nature , vol.413 , Issue.6857 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 25
    • 33646803561 scopus 로고    scopus 로고
    • TLR9 and TLR3 as essential components of innate immune defense against mouse cytomegalovirus
    • In Press
    • K. Tabeta et al., TLR9 and TLR3 as essential components of innate immune defense against mouse cytomegalovirus, Proc. Natl. Acad. Sci U.S.A. In Press. 2004.
    • (2004) Proc. Natl. Acad. Sci U.S.A.
    • Tabeta, K.1
  • 26
    • 0025774776 scopus 로고
    • Drosophila Toll and IL-1 receptor
    • N. J. Gay and F. J. Keith, Drosophila Toll and IL-1 receptor, Nature 351(6325), 355-356 (1991).
    • (1991) Nature , vol.351 , Issue.6325 , pp. 355-356
    • Gay, N.J.1    Keith, F.J.2
  • 27
    • 0025290213 scopus 로고
    • Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6
    • K. A. Lord, B. Hoffman-Liebermann, and D. A. Liebermann, Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6, Oncogene 5(7), 1095-1097 (1990).
    • (1990) Oncogene , vol.5 , Issue.7 , pp. 1095-1097
    • Lord, K.A.1    Hoffman-Liebermann, B.2    Liebermann, D.A.3
  • 28
    • 0028237775 scopus 로고
    • Macrophage differentiation marker MyD88 is a member of the Toll/IL-1 receptor family
    • D. Hultmark, Macrophage differentiation marker MyD88 is a member of the Toll/IL-1 receptor family, Biochem. Biophys. Res. Commun. 199(1), 144-146 (1994).
    • (1994) Biochem. Biophys. Res. Commun. , vol.199 , Issue.1 , pp. 144-146
    • Hultmark, D.1
  • 30
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • T. Kawai, O. Adachi, T. Ogawa, K. Takeda, and S. Akira, Unresponsiveness of MyD88-deficient mice to endotoxin, Immunity 11(1), 115-122 (1999).
    • (1999) Immunity , vol.11 , Issue.1 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 32
    • 0035555301 scopus 로고    scopus 로고
    • TIRAP: An adapter molecule in the Toll signaling pathway
    • T. Horng, G. M. Barton, and R. Medzhitov, TIRAP: an adapter molecule in the Toll signaling pathway, Nat. Immunol. 2(9), 835-841 (2001).
    • (2001) Nat. Immunol. , vol.2 , Issue.9 , pp. 835-841
    • Horng, T.1    Barton, G.M.2    Medzhitov, R.3
  • 33
    • 0037320451 scopus 로고    scopus 로고
    • TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction
    • H. Oshiumi, M. Matsumoto, K. Funami, T. Akazawa, and T. Seya, TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction, Nat. Immunol. 4:161-171 (2003).
    • (2003) Nat. Immunol. , vol.4 , pp. 161-171
    • Oshiumi, H.1    Matsumoto, M.2    Funami, K.3    Akazawa, T.4    Seya, T.5
  • 35
    • 0038448236 scopus 로고    scopus 로고
    • Lps2: A new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening
    • K. Hoebe, X. Du, J. Goode, N. Mann, and B. Beutler, Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening, J. Endotoxin Res. 9(4), 250-255 (2003).
    • (2003) J. Endotoxin Res. , vol.9 , Issue.4 , pp. 250-255
    • Hoebe, K.1    Du, X.2    Goode, J.3    Mann, N.4    Beutler, B.5
  • 37
    • 0037114185 scopus 로고    scopus 로고
    • Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
    • M. Yamamoto, S. Sato, K. Mori, K. Hoshino, O. Takeuchi, K. Takeda, and S. Akira, Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling, J. Immunol. 169(12), 6668-6672 (2002).
    • (2002) J. Immunol. , vol.169 , Issue.12 , pp. 6668-6672
    • Yamamoto, M.1    Sato, S.2    Mori, K.3    Hoshino, K.4    Takeuchi, O.5    Takeda, K.6    Akira, S.7
  • 40
    • 0007094269 scopus 로고
    • The formation of anti-sheep hemolytic amboceptor in the normal and tuberculous guinea pig
    • P. A. Lewis and D. Loomis, The formation of anti-sheep hemolytic amboceptor in the normal and tuberculous guinea pig, J. Exp. Med. 40:503 (1924).
    • (1924) J. Exp. Med. , vol.40 , pp. 503
    • Lewis, P.A.1    Loomis, D.2
  • 42
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • R. Medzhitov, P. Preston-Hurlburt, and C. A. Janeway, Jr., A human homologue of the Drosophila Toll protein signals activation of adaptive immunity, Nature 388(6640), 394-397 (1997).
    • (1997) Nature , vol.388 , Issue.6640 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 43
    • 0035339861 scopus 로고    scopus 로고
    • Endotoxin-induced maturation of myd88-deficient dendritic cells
    • T. Kaisho, O. Takeuchi, T. Kawai, K. Hoshino, and S. Akira, Endotoxin-induced maturation of myd88-deficient dendritic cells, J. Immunol. 166(9), 5688-5694 (2001).
    • (2001) J. Immunol. , vol.166 , Issue.9 , pp. 5688-5694
    • Kaisho, T.1    Takeuchi, O.2    Kawai, T.3    Hoshino, K.4    Akira, S.5
  • 44
    • 0034927975 scopus 로고    scopus 로고
    • Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice
    • T. Kaisho and S. Akira, Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice, Trends Immunol. 22(2), 78-83 (2001).
    • (2001) Trends Immunol. , vol.22 , Issue.2 , pp. 78-83
    • Kaisho, T.1    Akira, S.2
  • 45
    • 0347146027 scopus 로고    scopus 로고
    • Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways
    • K. Hoebe, E. M. Jannsen, S. O. Kim, L. Alexopoulou, R. A. Flavell, J. Han, and B. Beutler, Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways, Nature Immunology 4(12), 1223-1229 (2003).
    • (2003) Nature Immunology , vol.4 , Issue.12 , pp. 1223-1229
    • Hoebe, K.1    Jannsen, E.M.2    Kim, S.O.3    Alexopoulou, L.4    Flavell, R.A.5    Han, J.6    Beutler, B.7
  • 46
    • 0038714270 scopus 로고    scopus 로고
    • Poly(dI.dC)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
    • Z. Jiang, M. Zamanian-Daryoush, H. Nie, A. M. Silva, B. R. Williams, and X. Li, Poly(dI.dC)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR, J. Biol. Chem. 278(19), 16713-16719 (2003).
    • (2003) J. Biol. Chem. , vol.278 , Issue.19 , pp. 16713-16719
    • Jiang, Z.1    Zamanian-Daryoush, M.2    Nie, H.3    Silva, A.M.4    Williams, B.R.5    Li, X.6


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