CD4+ T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase

Cancer Research

Volumn 58, Issue 2, 1998, Pages 296-301

  Kobayashi, Hiroya ^a   Kokubo, Taku ^a   Sato, Keisuke ^a   Kimura, Shoji ^a   Asano, Kazuhiro ^a   Takahashi, Hidetoshi ^a   Iizuka, Hajime ^a   Miyokawa, Naoyuki ^a   Katagiri, Makoto ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MONOPHENOL MONOOXYGENASE;

ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CELL CLONE; CELLULAR IMMUNITY; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGENICITY; MELANOMA; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS TRANSFORMATION;

ANTIGEN-PRESENTING CELLS; ANTIGENS, NEOPLASM; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE, TRANSFORMED; CELL-FREE SYSTEM; CLONE CELLS; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HERPESVIRUS 4, HUMAN; HLA-DR ANTIGENS; HUMANS; MELANOMA; MONOPHENOL MONOOXYGENASE; PEPTIDE FRAGMENTS; PROTEIN BINDING; SKIN NEOPLASMS;

EID: 0031974381     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Levitsky, H. I., Lazenby, A., Hayashi, R., and Pardoll, D. M. In vivo priming of two distinct anti tumor effector populations: the role of MHC class I expression. J. Exp. Med., 179: 1215-1224, 1994.
2. Udono, H., Levey, D. L., and Srivastava, P. K. Cellular requirements for tumor-specific immunity elicited by heat shock proteins: tumor rejection antigen gp96 primes CD8+ T cells in vivo. Proc. Natl. Acad. Sci. USA, 91: 3077-3081, 1994.
3. Frey, A. Rat mammary adenocarcinoma 13762 expressing INF-γ elicits antitumor CD4+ MHC class II restricted T cells that are cytolytic in vitro and tumoricidal in vivo. J. Immunol., 154: 4613-4622, 1995.
4. Zatloukal, K., Schneeberger, A., Berger, M., Schmidt, W., Koszik, F., Kutil, R., Cotten, M., Wagner, E., Buschle, M., Maass, G., Payer, E., Stingl, G., and Brinstiel, M. L. Elicitation of a systemic and protective anti-melanoma immune response by an IL-2 based vaccine. Assessment of critical cellular and molecular parameters. J. Immunol., 152: 754-764, 1995.
5. Walter, E. A., Greenberg, P. D., Gilbert, M. J., Finch, R. J., Watanabe, K. S., Thomas, E. D., and Riddell, S. R. Recognition of cellular immunity against cytomegalovirus in recipients of allogenic bone marrow by transfer of T-cell clones from the donor. N. Engl. J. Med., 333: 1038-1044, 1995.
6. Topalian, S. L. MHC class II restricted tumor antigens and the role of CD4+ T cells in cancer immunotherapy. Curr. Opin. Immunol., 6: 741-745, 1994.
7. + T-cell immunity to mutated ras protein in pancreatic and colon cancer patients. Cancer Res., 55: 2984-2987, 1995.
8. Boon, T., Cerottini, J-C., Van den Eynde, B., van der Bruggen, P., and Van Pel, A. Tumor antigens recognized by T lymphocytes. Annu. Rev. Immunol., 12: 337-365, 1994.
9. Van der Bruggen, P., Traversari, C., Chomez, P., Lurquin, C., De Plaen, E., Van den Eynde, B., Knuth, A., and Boon, T. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science (Washington DC), 254: 1643-1647, 1991.
10. Birchard, V., Van Pel, A., Wolfel, T., Wolfel, C., De Plaen, E., Lethe, B., Coulie, P., and Boon, T. The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med., 178: 489-495, 1993.
11. Coulie, P. G., Brichard, V., Van Pel, A., Wolfel, T., Schneider, J., Traversari, C., Mattei, S., De Plaen, E., Lurquin, C., Szikora, J-P., Renauld, J-C., and Boon, T. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med., 180: 35-42, 1994.
12. Cox, A. L., Skipper, J., Chen, Y., Henderson, R. A., Darrow, T. L., Shabanowitz, J., Engelhard, V. H., Hunt, D., and Singluff, C. L. Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines. Science (Washington DC), 264: 716-719, 1994.
13. Gaugler, B., Van den Eynde, B., van der Bruggen, P., Romero, P., Gaforio, J., De Plaen, E., Lethe, B., Brasseur, F., and Boon, T. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. J. Exp. Med., 179: 921-930, 1994.
14. Kawakami, Y., Eliyahu, S., Delgado, C. H., Robbins, P. F., Rivoltini, L., Topalian, S. L., Miki, T., and Rosenberg, S. A. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc. Natl. Acad. Sci. USA, 91: 3515-3519, 1994.
15. Kawakami, Y., Eliyahu, S., Delgado, C. H., Robbins, P. F., Sakaguchi, K., Appella, E., Yannelli, J. R., Adema, G. J., Miki, T., and Rosenberg, S. A. Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proc. Natl. Acad. Sci. USA, 91: 6458-6482, 1994.
16. Salgaller, M. L., Afshar, A., Marincola, F. M., Rivoltini, L., Kawakami, Y., and Rosenberg, S. A. Recognition of multiple epitopes in the human melanoma antigen gp100 by peripheral blood lymphocytes stimulated in vitro with synthetic peptides. Cancer Res., 55: 4972-4979, 1995.
17. Kawakami, Y., Eliyahu, S., Sakaguchi, K., Robbins, P. F., Rivoltini, L., Yannelli, J. R., Appella, E., and Rosenberg, S. A. Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes. J. Exp. Med., 180: 347-352, 1994.
18. Kawakami, Y, Eliyahu, S., Jennings, C., Sakaguchi, K., Kang, X., Southwood, S., Robbins, P. F., Sette, A., Appella, E., and Rosenberg, S. A. Recognition multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression. J. Immunol., 154: 3961-3968, 1995.
19. Wolfel, T., Van Pel, A., Brichard, V., Schneider, J., Seliger, B., Meyer zum Buschenfelde, K-H., and Boon, T. Two tyrosinase nonapeptides recognized on HLA-A2 melanomas autologous cytolytic T lymphocytes. Eur. J. Immunol., 24: 759-764, 1994.
20. Kang, X., Kawakami, Y., El-Gamil, M., Wang, R., Sakaguchi, K., Yannelli, J. R., Appella, E., Rosenberg, S. A., and Robbins, P. F. Identification of a tyrosinase epitope recognized by HLA-A-24-restricted, tumor-infiltrating lymphocytes. J. Immunol., 155: 1343-1348, 1995.
21. Jim'enze, M., Kameyama, K., Maloy, W. L., Tomita, Y., and Hearing, V. J. Mammalian tyrosinase: biosynthesis, processing, and modulation by melanocyte-stimulating hormone. Proc. Natl. Acad. Sci. USA, 85: 3830-3834, 1988.
22. Fitzpatrick, T. B., Szabo, G., Seiji, M., and Quevedo, W. C. J. Biology of the melanin pigmentary system. In: T. B. Fitzpatrick, A. Z. Eisen, K. Wolff, I. M. Freedberg, and K. F. Austen (eds.). Dermatology in General Medicine, pp. 261-288. New York: McGraw-Hill, Inc., 1979.
23. Chen, Y-T., Stockert, E., Tsang, S., Coplan, A., and Old, L. J. Immunophenotyping of melanomas for tyrosinase: implications for vaccine development. Proc. Natl. Acad. Sci. USA, 92: 8125-8129, 1995.
24. Gedde-Dahl, T., Spurkland, A., Eriksen, J. A., Thorsby, E., and Gaudernack, G. Memory T cells of a patient with follicular thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln→Leu 61). Int. Immunol., 11: 1331-1337, 1992.
25. Gedde-Dahl, T., Eriksen, J. A., Thorsby, E., and Gaudernack, G. T-cell responses against products of oncogenes: generation and characterization of human T-cell clones specific for p21 ras-derived synthetic peptides. Hum. Immunol., 33: 266-274, 1992.
26. Topalian, S. L., Gonzales, M. I., Parkhurst, M., Li, Y. F., Southwood, S., Sette, A., Rosenberg, S. A., and Robbins, P, F. Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes. J. Exp. Med., 183: 1965-1971, 1996.
27. Heike, M., Schlaak, J., Schulze-Bergkamen, H., Heyl, S., Herr, W., Schmitt, U., Schneider, P. M., and zum Bushenfelde, K-H. M. Specificities and functions of CD4+ HLA class II-restricted T cell clones against a human sarcoma. Evidence for several recognized antigens. J. Immunol., 156: 2205-2213, 1996.
28. Peebles, P. T., Trish, T., and Papageorge, A. G. Isolation of four unusual pediatric solid tumor cell line. Pediatr. Res., 12: 485, 1978.
29. Topalian, S. L., Rivoltini, L., Mancini, M, Ng, J., Hartzman, R. J., and Rosenberg, S. A. Melanoma-specific CD4+ T lymphocytes recognize human melanoma antigens processed and presented by Epstein-Barr virus-transformed B cells. Int. J. Cancer, 58: 69-70, 1994.
30. Malcherek, G., Falk, K., Rotzschke, O., Rammensee, H-G., Stevanovic, S., Gnau, V., Jung, G., and Meims, A. Natural peptide ligand motifs of two HLA molecules associated with myasthenia gravis. Int. Immunol., 10: 1229-1237, 1993.
31. Stuhler, G., and Schlossman, S. F. Antigen organization regulates cluster formation and induction of cytotoxic T lymphocytes by helper T cell subsets. Proc. Natl. Acad. Sci. USA, 94: 622-627, 1997.
32. Yee, C., Gilbert, M. J., Riddell, S. R., Brichard, V. G., Fefer, A., Thompson, J. A., Boon, T., and Greenberg, P. D. Isolation of tyrosinase-specific CD8+ and CD4+ T cell clones from the peripheral blood of melanoma patients following in vitro stimulation with recombinant vaccinia virus. J. Immunol., 157: 4079-4086, 1996.
33. Nuchtern, J. G., Biddison, W. E., and Klausner, R. D. Class II MHC molecules can use the endogenous pathway of antigen presentation. Nature (Lond.), 343: 74-76, 1990.
34. Dice, J. F. Peptide sequences that target cytosolic proteins for lysosomal proteolysis. Trends Biochem. Sci., 15: 305-309, 1990.
35. Terlecky, S. R., Chiang, H-L., Oslon, T. S., and Dice, J. F. Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-KDa heat shock cognate protein. J. Biol. Chem., 267: 9207-9209, 1992.
36. Rudensky, A. Y., Maric, M., Eastman, S., Shoemaker, L., DeRoos, P. C., and Blim, J. S. Intracellular assembly and transport of endogenous peptide-MHC class II complex. Immunity, 1: 585-594, 1994.
37. Oxenius, A., Bachmann, M. F., Ashton-Rickardt, P. G., Tonegawa, S., Zinkernagel, R. M., and Hengartner, H. Presentation of endogenous viral protein in association with major histocompatibility complex class II: on the role of intracellular compartmentalization, invariant chain and TAP transporter system. Eur. J. Immunol., 25: 3402-3411, 1995.
38. Zhou, B-K., Boissy, R. E., Pifko-Hirst, S., Moran, D. I., and Orlow, S. J. Lysosome-associated membrane protein-1 (LAMP-1) is the melanocyte vesicular membrane glycoprotein band. J. Invest. Dermatol., 100: 110-114, 1993.