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Volumn 43, Issue 4, 2007, Pages 117-137

Vascular biology in sepsis: Pathophysiological and therapeutic significance of vascular dysfunction

Author keywords

Apoptosis; Endothelium; Endotoxin; Microcirculation; Sepsis

Indexed keywords

BLOOD CLOTTING FACTOR;

EID: 35649015324     PISSN: 09168737     EISSN: None     Source Type: Journal    
DOI: 10.1540/jsmr.43.117     Document Type: Review
Times cited : (119)

References (151)
  • 1
    • 26944473627 scopus 로고    scopus 로고
    • Glucocorticoids in the treatment of severe sepsis and septic shock
    • Annane, D. (2005). Glucocorticoids in the treatment of severe sepsis and septic shock. Curr. Opin. Crit. Care 11: 449-453.
    • (2005) Curr. Opin. Crit. Care , vol.11 , pp. 449-453
    • Annane, D.1
  • 2
    • 0028796672 scopus 로고
    • Microvascular function and rheologic changes in hyperdynamic sepsis
    • Astiz, M.E., DeGent, G.E., Lin, R.Y. and Rackow, E.C. (1995). Microvascular function and rheologic changes in hyperdynamic sepsis. Crit. Care Med. 23: 265-271.
    • (1995) Crit. Care Med , vol.23 , pp. 265-271
    • Astiz, M.E.1    DeGent, G.E.2    Lin, R.Y.3    Rackow, E.C.4
  • 3
    • 0030769929 scopus 로고    scopus 로고
    • Nitric oxide causes dysfunction of coronary autoregulation in endotoxemic rats
    • Avontuur, J.A., Bruining, H.A. and Ince, C. (1997). Nitric oxide causes dysfunction of coronary autoregulation in endotoxemic rats. Cardiovasc. Res. 35: 368-376.
    • (1997) Cardiovasc. Res , vol.35 , pp. 368-376
    • Avontuur, J.A.1    Bruining, H.A.2    Ince, C.3
  • 4
    • 0033557372 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-κB
    • Badrichani, A.Z., Stroka, D.M., Bilbao, G., Curiel, D.T., Bach, F.H. and Ferran, C. (1999). Bcl-2 and Bcl-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-κB. J. Clin. Invest. 103: 543-553.
    • (1999) J. Clin. Invest , vol.103 , pp. 543-553
    • Badrichani, A.Z.1    Stroka, D.M.2    Bilbao, G.3    Curiel, D.T.4    Bach, F.H.5    Ferran, C.6
  • 5
    • 0032567463 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide disrupts endothelial monolayer integrity and survival signaling events through caspase cleavage of adherens junction proteins
    • Bannerman, D.D., Sathyamoorthy, M. and Goldblum, S.E. (1998). Bacterial lipopolysaccharide disrupts endothelial monolayer integrity and survival signaling events through caspase cleavage of adherens junction proteins. J. Biol. Chem. 273: 35371-35380.
    • (1998) J. Biol. Chem , vol.273 , pp. 35371-35380
    • Bannerman, D.D.1    Sathyamoorthy, M.2    Goldblum, S.E.3
  • 6
    • 0036172129 scopus 로고    scopus 로고
    • The Fas-associated death domain protein suppresses activation of NF-κB by LPS and IL-1β
    • Bannerman, D.D., Tupper, J.C., Kelly, J.D., Winn, R.K. and Harlan, J.M. (2002). The Fas-associated death domain protein suppresses activation of NF-κB by LPS and IL-1β. J. Clin. Invest. 109: 419-425.
    • (2002) J. Clin. Invest , vol.109 , pp. 419-425
    • Bannerman, D.D.1    Tupper, J.C.2    Kelly, J.D.3    Winn, R.K.4    Harlan, J.M.5
  • 7
    • 0035805493 scopus 로고    scopus 로고
    • A constitutive cytoprotective pathway protects endothelial cells from lipopolysaccharide-induced sepsis
    • Bannerman, D.D., Tupper, J.C., Ricketts, W.A., Bennet, C.F., Winn, R.K. and Harlan, J.M. (2001). A constitutive cytoprotective pathway protects endothelial cells from lipopolysaccharide-induced sepsis. J. Biol. Chem. 276: 14924-14932.
    • (2001) J. Biol. Chem , vol.276 , pp. 14924-14932
    • Bannerman, D.D.1    Tupper, J.C.2    Ricketts, W.A.3    Bennet, C.F.4    Winn, R.K.5    Harlan, J.M.6
  • 9
    • 0025865703 scopus 로고
    • Experimental models of pathologic oxygen supply dependency
    • Cain, S.M. and Curtis, S.E. (1991). Experimental models of pathologic oxygen supply dependency. Crit. Care Med. 19: 603-612.
    • (1991) Crit. Care Med , vol.19 , pp. 603-612
    • Cain, S.M.1    Curtis, S.E.2
  • 11
    • 0034648529 scopus 로고    scopus 로고
    • Activation of the NF-κB pathway by caspase-8 and its homolog
    • Chaudhary, P.M., Eby, M.T., Jasmin, A., Kumar, A., Liu, L. and Hood, L. (2000). Activation of the NF-κB pathway by caspase-8 and its homolog. Oncogene 19: 4451-4460.
    • (2000) Oncogene , vol.19 , pp. 4451-4460
    • Chaudhary, P.M.1    Eby, M.T.2    Jasmin, A.3    Kumar, A.4    Liu, L.5    Hood, L.6
  • 12
    • 0033781702 scopus 로고    scopus 로고
    • + channels in aortic smooth muscle of rats with endotoxic shock: Electrophysiological and functional evidence
    • + channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence. Br. J. Pharmacol. 131: 213-222.
    • (2000) Br. J. Pharmacol , vol.131 , pp. 213-222
    • Chen, S.-J.1    Wu, C.-C.2    Yang, S.-N.3    Lin, C.-I.4    Yen, M.-H.5
  • 13
    • 0020148444 scopus 로고
    • Endogenous and exogenous catecholamines in critical care medicine
    • Chernow, B., Rainey, T.G. and Lake, C.R. (1982). Endogenous and exogenous catecholamines in critical care medicine. Crit. Care Med. 10: 409-416.
    • (1982) Crit. Care Med , vol.10 , pp. 409-416
    • Chernow, B.1    Rainey, T.G.2    Lake, C.R.3
  • 14
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • Cohen, J. (2002). The immunopathogenesis of sepsis. Nature 420: 885-891.
    • (2002) Nature , vol.420 , pp. 885-891
    • Cohen, J.1
  • 15
    • 0018600214 scopus 로고
    • Direct measurement of arteiovenous anastomotic blood flow in the septic canine hindlimb
    • Cronenwett, J.L. and Lindenauer, S.M. (1979). Direct measurement of arteiovenous anastomotic blood flow in the septic canine hindlimb. Surgery 85: 275-282.
    • (1979) Surgery , vol.85 , pp. 275-282
    • Cronenwett, J.L.1    Lindenauer, S.M.2
  • 16
    • 0023142538 scopus 로고
    • Skeletal microcirculatory responses to hyperdynamic Escherichia coli sepsis in unanesthetized rats
    • Cryer, H.M., Garrison, R.N., Kaebnick, H.W., Harris, P.D. and Fint, L.M. (1987). Skeletal microcirculatory responses to hyperdynamic Escherichia coli sepsis in unanesthetized rats. Arch. Surg. 122: 86-92.
    • (1987) Arch. Surg , vol.122 , pp. 86-92
    • Cryer, H.M.1    Garrison, R.N.2    Kaebnick, H.W.3    Harris, P.D.4    Fint, L.M.5
  • 17
    • 0023898074 scopus 로고
    • Acute inflammation and microthrombosis induced by endotoxin, interleukin-1, and tumor necrosis factor and their implication in gram-negative infection
    • Cybulsky, M.I., Chan, M.K. and Movat, H.Z. (1988). Acute inflammation and microthrombosis induced by endotoxin, interleukin-1, and tumor necrosis factor and their implication in gram-negative infection. Lab. Invest. 58: 365-378.
    • (1988) Lab. Invest , vol.58 , pp. 365-378
    • Cybulsky, M.I.1    Chan, M.K.2    Movat, H.Z.3
  • 18
    • 0034045654 scopus 로고    scopus 로고
    • Induction of the ATP-sensitive potassium (uKATP-1) channel by endotoxemia
    • Czaika, G., Gingras, Y., Zhu, E. and Comtois, A.S. (2000). Induction of the ATP-sensitive potassium (uKATP-1) channel by endotoxemia. Muscle Nerve 23: 967-969.
    • (2000) Muscle Nerve , vol.23 , pp. 967-969
    • Czaika, G.1    Gingras, Y.2    Zhu, E.3    Comtois, A.S.4
  • 19
    • 0032986039 scopus 로고    scopus 로고
    • Modulation of caspase-3 activity and Fas ligand mRNA expression in rat liver cells in vivo by alcohol and lipopolysaccharide
    • Deaciuc, I.V., Fortunato, F., D'Souza, N.B., Hill, D.B., Schmidt, J., Lee, E.Y. and McClain, C.J. (1999). Modulation of caspase-3 activity and Fas ligand mRNA expression in rat liver cells in vivo by alcohol and lipopolysaccharide. Alcohol Clin. Exp. Res. 23: 349-356.
    • (1999) Alcohol Clin. Exp. Res , vol.23 , pp. 349-356
    • Deaciuc, I.V.1    Fortunato, F.2    D'Souza, N.B.3    Hill, D.B.4    Schmidt, J.5    Lee, E.Y.6    McClain, C.J.7
  • 23
    • 0031984113 scopus 로고    scopus 로고
    • Histochemical and ultrastructural study of skeletal muscle in patients with sepsis and multiple organ failure syndrome (MOFS)
    • Diaz, N.L., Finol, H.J., Torres, S.H., Zambrano, C.I. and Adjounian, H. (1998). Histochemical and ultrastructural study of skeletal muscle in patients with sepsis and multiple organ failure syndrome (MOFS). Histol. Histopathol. 13: 121-128.
    • (1998) Histol. Histopathol , vol.13 , pp. 121-128
    • Diaz, N.L.1    Finol, H.J.2    Torres, S.H.3    Zambrano, C.I.4    Adjounian, H.5
  • 24
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells via Akt-dependent phosphorylation
    • Dimmeler, S., Fleming, I., Fisslthaler, B., Hermann, C., Busse, R. and Zeiher, A.M. (1999). Activation of nitric oxide synthase in endothelial cells via Akt-dependent phosphorylation. Nature 399: 601-605.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 25
    • 0025271844 scopus 로고
    • Tumor necrosis factor-α induction of novel gene products in human endothelial cells including a macrophage-specific chemotoxin
    • Dixt, V.M., Green, S., Sarma, V., Holzman, L.B., Wolf, F.W., O'Rourke, K., Ward, P.A., Prochownik, E.V. and Marks, R.M. (1990). Tumor necrosis factor-α induction of novel gene products in human endothelial cells including a macrophage-specific chemotoxin. J. Biol. Chem. 265: 27201-27204.
    • (1990) J. Biol. Chem , vol.265 , pp. 27201-27204
    • Dixt, V.M.1    Green, S.2    Sarma, V.3    Holzman, L.B.4    Wolf, F.W.5    O'Rourke, K.6    Ward, P.A.7    Prochownik, E.V.8    Marks, R.M.9
  • 26
    • 0027725139 scopus 로고
    • Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis
    • Drake, T.A., Cheng, J., Chang, A. and Taylor, F.B.Jr. (1993). Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis. Am. J. Pathol. 142: 1458-1470.
    • (1993) Am. J. Pathol , vol.142 , pp. 1458-1470
    • Drake, T.A.1    Cheng, J.2    Chang, A.3    Taylor Jr., F.B.4
  • 27
    • 0026537719 scopus 로고
    • Regulation of perfused capillary density in canine intestinal mucosa during endotoxemia
    • Drazenovic, R., Samsel, R.W., Wylam, M.E., Doerschuk, C.M. and Schumacker, P.T. (1992). Regulation of perfused capillary density in canine intestinal mucosa during endotoxemia. J. Appl. Physiol. 72: 259-265.
    • (1992) J. Appl. Physiol , vol.72 , pp. 259-265
    • Drazenovic, R.1    Samsel, R.W.2    Wylam, M.E.3    Doerschuk, C.M.4    Schumacker, P.T.5
  • 29
    • 0038298224 scopus 로고    scopus 로고
    • Effects of in vivo lipopolysaccharide infusion on vasoconstrictor function of rat isolated mesentery, kidney, and aorta
    • Farmer, M.R., Roberts, R.E., Gardiner, S.M. and Ralevic, V. (2003). Effects of in vivo lipopolysaccharide infusion on vasoconstrictor function of rat isolated mesentery, kidney, and aorta. J. Pharmacol. Exp. Ther. 306: 538-545.
    • (2003) J. Pharmacol. Exp. Ther , vol.306 , pp. 538-545
    • Farmer, M.R.1    Roberts, R.E.2    Gardiner, S.M.3    Ralevic, V.4
  • 30
    • 0030065143 scopus 로고    scopus 로고
    • Decreased capillary density in vivo in bowel mucosa of rats with normotensive sepsis
    • Farquhar, I., Martin, C.M., Lam, C., Potter, R., Ellis, C.G. and Sibbald, W.J. (1996). Decreased capillary density in vivo in bowel mucosa of rats with normotensive sepsis. J. Surg. Res. 61: 190-196.
    • (1996) J. Surg. Res , vol.61 , pp. 190-196
    • Farquhar, I.1    Martin, C.M.2    Lam, C.3    Potter, R.4    Ellis, C.G.5    Sibbald, W.J.6
  • 32
    • 0030915285 scopus 로고    scopus 로고
    • Endothelial barrier dysfunction and p42 oxidation uinduced by TNF-α are mediated by nitric oxide
    • Ferro, T.J., Gertzberg, N., Selden, L., Neumann, P. and Johnson, A. (1997). Endothelial barrier dysfunction and p42 oxidation uinduced by TNF-α are mediated by nitric oxide. Am. J. Physiol. 272: L979-L988.
    • (1997) Am. J. Physiol , vol.272
    • Ferro, T.J.1    Gertzberg, N.2    Selden, L.3    Neumann, P.4    Johnson, A.5
  • 33
    • 0033949332 scopus 로고    scopus 로고
    • Protein kinase C-α mediates endothelial barrier dysfunction induced by TNF-α
    • Ferro, T., Neumann, P., Gertzberg, N., Clements, R. and Johnson, A. (2000). Protein kinase C-α mediates endothelial barrier dysfunction induced by TNF-α. Am. J. Physiol. 278: L1107-L1117.
    • (2000) Am. J. Physiol , vol.278
    • Ferro, T.1    Neumann, P.2    Gertzberg, N.3    Clements, R.4    Johnson, A.5
  • 34
    • 0030631768 scopus 로고    scopus 로고
    • Cytopathic hypoxia in sepsis
    • Fink, M. (1997). Cytopathic hypoxia in sepsis. Acta Anaesthesiol. Scand. Suppl. 110: 87-95.
    • (1997) Acta Anaesthesiol. Scand. Suppl , vol.110 , pp. 87-95
    • Fink, M.1
  • 35
    • 0022378119 scopus 로고
    • Diminished pressor response to exogenous norepinephrine and angiotensin II in septic, unanesthetized rats: Evidence for a prostaglandin-mediated effect
    • Fink, M.P., Homer, L.D. and Fletcher, J.R. (1985). Diminished pressor response to exogenous norepinephrine and angiotensin II in septic, unanesthetized rats: evidence for a prostaglandin-mediated effect. J. Surg. Res. 38: 335-342.
    • (1985) J. Surg. Res , vol.38 , pp. 335-342
    • Fink, M.P.1    Homer, L.D.2    Fletcher, J.R.3
  • 36
    • 0025811660 scopus 로고
    • Evidence that an L-arginine/ nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin
    • Fleming, I., Julou-Schaeffer, G., Gray, G.A., Parrat, J.R. and Stoclet, J.-C. (1991). Evidence that an L-arginine/ nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin. Br. J. Pharmacol. 103: 1047-1052.
    • (1991) Br. J. Pharmacol , vol.103 , pp. 1047-1052
    • Fleming, I.1    Julou-Schaeffer, G.2    Gray, G.A.3    Parrat, J.R.4    Stoclet, J.-C.5
  • 37
    • 0345487501 scopus 로고    scopus 로고
    • Lipopolysaccharide induces apoptosis in a bovine endothelial cell line via a soluble CD14-dependent pathway
    • Frey, E.A. and Finlay, B.B. (1998). Lipopolysaccharide induces apoptosis in a bovine endothelial cell line via a soluble CD14-dependent pathway. Microb. Patholog. 24: 101-109.
    • (1998) Microb. Patholog , vol.24 , pp. 101-109
    • Frey, E.A.1    Finlay, B.B.2
  • 41
    • 0034121166 scopus 로고    scopus 로고
    • Nitric oxide produced via neuronal NOS may impair vasodilation in septic rat skeletal muscle
    • Gocan, N.C., Scott, J.A. and Tyml, K. (2000). Nitric oxide produced via neuronal NOS may impair vasodilation in septic rat skeletal muscle. Am. J. Physiol. 278: H1480-H1489.
    • (2000) Am. J. Physiol , vol.278
    • Gocan, N.C.1    Scott, J.A.2    Tyml, K.3
  • 42
    • 0027461977 scopus 로고
    • TNF-α induces endothelial cell F-actin depolymerization, new actin synthesis, and barrier dysfunction
    • Goldblum, S.E., Ding, X. and Campbell-Washington, J. (1993). TNF-α induces endothelial cell F-actin depolymerization, new actin synthesis, and barrier dysfunction. Am. J. Physiol. 264: C894-C905.
    • (1993) Am. J. Physiol , vol.264
    • Goldblum, S.E.1    Ding, X.2    Campbell-Washington, J.3
  • 43
    • 0036172514 scopus 로고    scopus 로고
    • The tissue factor and plasminogen activator inhibitor type-1 response in pediatric sepsis-induced multiple organ failure
    • Green, J., Doughty, L., Kaplan, S.S., Sasser, H. and Carcillo, J.A. (2002). The tissue factor and plasminogen activator inhibitor type-1 response in pediatric sepsis-induced multiple organ failure. Thromb. Haemost. 87: 218-223.
    • (2002) Thromb. Haemost , vol.87 , pp. 218-223
    • Green, J.1    Doughty, L.2    Kaplan, S.S.3    Sasser, H.4    Carcillo, J.A.5
  • 44
    • 0028924241 scopus 로고
    • In vivo treatment with endotoxin induces nitric oxide synthase in rat main pulmonary artery
    • Griffiths, M.J.D., Liu, S., Curzen, N.P., Messent, M. and Evans, T.W. (1995). In vivo treatment with endotoxin induces nitric oxide synthase in rat main pulmonary artery. Am. J. Physiol. 268: L509-L518.
    • (1995) Am. J. Physiol , vol.268
    • Griffiths, M.J.D.1    Liu, S.2    Curzen, N.P.3    Messent, M.4    Evans, T.W.5
  • 45
    • 0022646738 scopus 로고
    • Hemodynamic determinants of mortality in human septic shock
    • Groeneveld, A.B., Bronsveld, W. and Thijs, L.G. (1986). Hemodynamic determinants of mortality in human septic shock. Surgery 99: 140-153.
    • (1986) Surgery , vol.99 , pp. 140-153
    • Groeneveld, A.B.1    Bronsveld, W.2    Thijs, L.G.3
  • 46
    • 0031648469 scopus 로고    scopus 로고
    • The nitric oxide donor sodium nitroprusside protects against hepatic microcirculatory dysfunction in early endotoxemia
    • Gundersen, Y., Corso, C.O., Leiderer, R., Dorger, M., Lilleaasen, P., Assen, A.O. and Messmer, K. (1998). The nitric oxide donor sodium nitroprusside protects against hepatic microcirculatory dysfunction in early endotoxemia. Intensive Care Med. 24: 1257-1263.
    • (1998) Intensive Care Med , vol.24 , pp. 1257-1263
    • Gundersen, Y.1    Corso, C.O.2    Leiderer, R.3    Dorger, M.4    Lilleaasen, P.5    Assen, A.O.6    Messmer, K.7
  • 47
    • 0031874939 scopus 로고    scopus 로고
    • Vascular effects of LPS in mice deficient in expression of the gene for inducible nitric oxide synthase
    • Gunnett, C.A., Chu, Y., Heistad, D.D., Loihl, A. and Faraci, F.M. (1998). Vascular effects of LPS in mice deficient in expression of the gene for inducible nitric oxide synthase. Am. J. Physiol. 275: H416-H421.
    • (1998) Am. J. Physiol , vol.275
    • Gunnett, C.A.1    Chu, Y.2    Heistad, D.D.3    Loihl, A.4    Faraci, F.M.5
  • 48
    • 0030784482 scopus 로고    scopus 로고
    • Haimovitz-Friedman, A., Cordon-Cardo, C., Bayoumy, S., Garzotto, M., McLoughlin, M., Gallily, R., Edwards, C.K.III., Schuchman, E.H., Fucks, Z. and Kolesnick, R. (1997). Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. J. Exp. Med. 186: 1831-1841.
    • Haimovitz-Friedman, A., Cordon-Cardo, C., Bayoumy, S., Garzotto, M., McLoughlin, M., Gallily, R., Edwards, C.K.III., Schuchman, E.H., Fucks, Z. and Kolesnick, R. (1997). Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. J. Exp. Med. 186: 1831-1841.
  • 49
    • 0028030618 scopus 로고
    • Skeletal muscle oedema and muscle fibre necrosis during septic shock. Observations with a porcine septic shock model
    • Hauptmann, S., Klosterhalfen, B., Weis, J., Mittermayer, C. and Kirkpatrick, C.J. (1994). Skeletal muscle oedema and muscle fibre necrosis during septic shock. Observations with a porcine septic shock model. Virchows Arch. 424: 653-659.
    • (1994) Virchows Arch , vol.424 , pp. 653-659
    • Hauptmann, S.1    Klosterhalfen, B.2    Weis, J.3    Mittermayer, C.4    Kirkpatrick, C.J.5
  • 50
    • 0035488777 scopus 로고    scopus 로고
    • Inhibition of cytokine-induced NF-κB activation by asenovirus-mediated expression of a NF-κB super-repressor prevents β-cell apoptosis
    • Heimberg, H., Heremans, Y., Jobin, C., Leemans, R., Cardozo, A.K., Darville, M. and Eizirik, D.L. (2001). Inhibition of cytokine-induced NF-κB activation by asenovirus-mediated expression of a NF-κB super-repressor prevents β-cell apoptosis. Diabetes 50: 2219-2224.
    • (2001) Diabetes , vol.50 , pp. 2219-2224
    • Heimberg, H.1    Heremans, Y.2    Jobin, C.3    Leemans, R.4    Cardozo, A.K.5    Darville, M.6    Eizirik, D.L.7
  • 51
    • 0034902552 scopus 로고    scopus 로고
    • Protective effect of neurotropin against lipopolysaccharide-induced hypotension and lethality linked to suppression of inducible nitric oxide synthase induction
    • Higaki, A., Ninomiya, H., Saji, M., Maki, H., Koike, T. and Ohno, K. (2001). Protective effect of neurotropin against lipopolysaccharide-induced hypotension and lethality linked to suppression of inducible nitric oxide synthase induction. Jpn. J. Pharmacol. 86: 329-335.
    • (2001) Jpn. J. Pharmacol , vol.86 , pp. 329-335
    • Higaki, A.1    Ninomiya, H.2    Saji, M.3    Maki, H.4    Koike, T.5    Ohno, K.6
  • 55
    • 0028895510 scopus 로고
    • Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells
    • Hoyt, D.G., Mannix, R.J., Rusnak, J.M., Pitt, B.R. and Lazo, J.S. (1995). Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells. Am. J. Physiol. 269: L171-L177.
    • (1995) Am. J. Physiol , vol.269
    • Hoyt, D.G.1    Mannix, R.J.2    Rusnak, J.M.3    Pitt, B.R.4    Lazo, J.S.5
  • 56
    • 0034646478 scopus 로고    scopus 로고
    • Activation of NF-κB by FADD, Casper, and caspase-8
    • Hu, W.H., Johnson, H. and Shu, H.B. (2000). Activation of NF-κB by FADD, Casper, and caspase-8. J. Biol. Chem. 275: 10838-10844.
    • (2000) J. Biol. Chem , vol.275 , pp. 10838-10844
    • Hu, W.H.1    Johnson, H.2    Shu, H.B.3
  • 57
    • 0032531994 scopus 로고    scopus 로고
    • Lipopolysaccharide induces the antiapoptotic molecules, A1 and A20, in microvascular endothelial cells
    • Hu, X., Yee, E., Harlan, J.M., Wong, F. and Karsan, A. (1998). Lipopolysaccharide induces the antiapoptotic molecules, A1 and A20, in microvascular endothelial cells. Blood 92: 2759-2765.
    • (1998) Blood , vol.92 , pp. 2759-2765
    • Hu, X.1    Yee, E.2    Harlan, J.M.3    Wong, F.4    Karsan, A.5
  • 58
    • 0029746049 scopus 로고    scopus 로고
    • Heterogeneity of gut capillary transit times and impaired gut oxygen extraction in endotoxemic pigs
    • Humer, M.F., Phang, P.T., Friesen, B.P., Allard, M.F., Goddard, C.M. and Walley, K.R. (1996). Heterogeneity of gut capillary transit times and impaired gut oxygen extraction in endotoxemic pigs. J. Appl. Physiol. 81: 895-904.
    • (1996) J. Appl. Physiol , vol.81 , pp. 895-904
    • Humer, M.F.1    Phang, P.T.2    Friesen, B.P.3    Allard, M.F.4    Goddard, C.M.5    Walley, K.R.6
  • 59
    • 0033847782 scopus 로고    scopus 로고
    • Microcirculatory weak units - an alternative explanation
    • Ince, C. (2000). Microcirculatory weak units - an alternative explanation. Crit. Care Med. 28: 3127-3129.
    • (2000) Crit. Care Med , vol.28 , pp. 3127-3129
    • Ince, C.1
  • 61
    • 0024559412 scopus 로고
    • Human recombinant tumor necrosis factor ? infusion mimics endotoxemia in awake sheep
    • Johnson, J., Meyrick, B., Jesmok, G. and Brigham, K.L. (1989). Human recombinant tumor necrosis factor ? infusion mimics endotoxemia in awake sheep. J. Appl. Physiol. 66: 1448-1454.
    • (1989) J. Appl. Physiol , vol.66 , pp. 1448-1454
    • Johnson, J.1    Meyrick, B.2    Jesmok, G.3    Brigham, K.L.4
  • 64
    • 0029861518 scopus 로고    scopus 로고
    • Endothelial cell death induced by tumor necrosis factor-α is inhibited by the Bcl-2 family member A1
    • Karsan, A., Yee, E. and Harlan, J.M. (1996). Endothelial cell death induced by tumor necrosis factor-α is inhibited by the Bcl-2 family member A1. J. Biol. Chem. 271: 27201-27204.
    • (1996) J. Biol. Chem , vol.271 , pp. 27201-27204
    • Karsan, A.1    Yee, E.2    Harlan, J.M.3
  • 66
    • 0033873787 scopus 로고    scopus 로고
    • Protection from lethal apoptosis in lipopolysaccharide-induced acute lung injury in mice by a caspase inhibitor
    • Kawasaki, M., Kuwano, K., Hagimoto, N., Matsuba, T., Kunitake, R., Tanaka, T., Maeyama, T. and Hara, N. (2000). Protection from lethal apoptosis in lipopolysaccharide-induced acute lung injury in mice by a caspase inhibitor. Am. J. Pathol. 157: 597-603.
    • (2000) Am. J. Pathol , vol.157 , pp. 597-603
    • Kawasaki, M.1    Kuwano, K.2    Hagimoto, N.3    Matsuba, T.4    Kunitake, R.5    Tanaka, T.6    Maeyama, T.7    Hara, N.8
  • 67
    • 0027145159 scopus 로고
    • Enteric vascular endothelial response to bacterial endotoxin
    • Koshi, R., Methan, V.I., David, S. and Mathan, M.M. (1993). Enteric vascular endothelial response to bacterial endotoxin. Int. J. Exp. Pathol. 74: 593-601.
    • (1993) Int. J. Exp. Pathol , vol.74 , pp. 593-601
    • Koshi, R.1    Methan, V.I.2    David, S.3    Mathan, M.M.4
  • 68
    • 0032410818 scopus 로고    scopus 로고
    • The inhibitors of apoptosis (IAPs) and their emerging role in cancer
    • LaCasse, E.C., Baird, S., Korneluk, R.G. and MacKenzie, A.E. (1998). The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 17: 3247-3259.
    • (1998) Oncogene , vol.17 , pp. 3247-3259
    • LaCasse, E.C.1    Baird, S.2    Korneluk, R.G.3    MacKenzie, A.E.4
  • 69
    • 0028053865 scopus 로고
    • Microvascular perfusion is impaired in a rat model of normotensive sepsis
    • Lam, C., Tyml, K., Martin, C. and Sibbald, W. (1994). Microvascular perfusion is impaired in a rat model of normotensive sepsis. J. Clin. Invest. 94: 2077-2083.
    • (1994) J. Clin. Invest , vol.94 , pp. 2077-2083
    • Lam, C.1    Tyml, K.2    Martin, C.3    Sibbald, W.4
  • 70
    • 0026643053 scopus 로고
    • + channel mediates hypotension in endotoxemia and hypoxic lactic acidosis in dogs
    • + channel mediates hypotension in endotoxemia and hypoxic lactic acidosis in dogs. J. Clin. Invest. 89: 2071-2074.
    • (1992) J. Clin. Invest , vol.89 , pp. 2071-2074
    • Landry, D.W.1    Oliver, J.A.2
  • 71
    • 0028575633 scopus 로고
    • Distinct patterns of nitric oxide production in hepatic macrophages and endothelial cells following acute exposure of rats to endotoxin
    • Laskin, D.L., Heck, D.E., Gardner, C.R., Feder, L.S. and Laskin, J.D. (1994). Distinct patterns of nitric oxide production in hepatic macrophages and endothelial cells following acute exposure of rats to endotoxin. J. Leukoc. Biol. 56: 751-758.
    • (1994) J. Leukoc. Biol , vol.56 , pp. 751-758
    • Laskin, D.L.1    Heck, D.E.2    Gardner, C.R.3    Feder, L.S.4    Laskin, J.D.5
  • 72
    • 0034008116 scopus 로고    scopus 로고
    • Microcirculatory dysfunction in sepsis: A pathogenetic basis for therapy?
    • Lehr, H.A., Bittinger, F. and Kirkpatrick, C.J. (2000). Microcirculatory dysfunction in sepsis: a pathogenetic basis for therapy? J. Pathol. 190: 373-386.
    • (2000) J. Pathol , vol.190 , pp. 373-386
    • Lehr, H.A.1    Bittinger, F.2    Kirkpatrick, C.J.3
  • 73
    • 0642373576 scopus 로고    scopus 로고
    • Infection and inflammation and the coagulation system
    • Levi, M., Keller, T.T., van Gorp, E. and ten Cate, H. (2003). Infection and inflammation and the coagulation system. Cardiovasc. Res. 60: 26-39.
    • (2003) Cardiovasc. Res , vol.60 , pp. 26-39
    • Levi, M.1    Keller, T.T.2    van Gorp, E.3    ten Cate, H.4
  • 74
    • 0031784698 scopus 로고    scopus 로고
    • Passive deformability of mature, immature, and active neutrophils in healthy and septicemic neonates
    • Linderkamp, O., Ruef, P., Brenner, B., Gulbins, E. and Lang, F. (1998). Passive deformability of mature, immature, and active neutrophils in healthy and septicemic neonates. Pediatr. Res. 44: 946-950.
    • (1998) Pediatr. Res , vol.44 , pp. 946-950
    • Linderkamp, O.1    Ruef, P.2    Brenner, B.3    Gulbins, E.4    Lang, F.5
  • 75
    • 0034168402 scopus 로고    scopus 로고
    • Microvascular dysfunction in sepsis
    • Lush, C.W. and Kvietys, R.R. (2000). Microvascular dysfunction in sepsis. Microcirculation 7: 83-101.
    • (2000) Microcirculation , vol.7 , pp. 83-101
    • Lush, C.W.1    Kvietys, R.R.2
  • 76
    • 0032909817 scopus 로고    scopus 로고
    • Depexamine attenuates flow motion in ileal mucosal arterioles in normotensive sepsis
    • Madorin, W.S., Martin, C.M. and Sibbald, W.J. (1999). Depexamine attenuates flow motion in ileal mucosal arterioles in normotensive sepsis. Crit. Care Med. 27: 394-400.
    • (1999) Crit. Care Med , vol.27 , pp. 394-400
    • Madorin, W.S.1    Martin, C.M.2    Sibbald, W.J.3
  • 77
    • 15744394565 scopus 로고    scopus 로고
    • Nuclear factor-κB decoy oligodeoxynucleotides prevent acute lung injury in mice with cecal ligation and puncture-induced sepsis
    • Matsuda, N., Hattori, Y., Jesmin, S. and Gando, S. (2005). Nuclear factor-κB decoy oligodeoxynucleotides prevent acute lung injury in mice with cecal ligation and puncture-induced sepsis. Mol. Pharmacol. 67: 1018-1025.
    • (2005) Mol. Pharmacol , vol.67 , pp. 1018-1025
    • Matsuda, N.1    Hattori, Y.2    Jesmin, S.3    Gando, S.4
  • 80
    • 33751166411 scopus 로고    scopus 로고
    • Phosphorylation of endothelial nitricoxide synthase is diminished in mesenteric arteries from septic rabbits depending on the altered phosphatidylinositol 3-kinase/Akt pathway: Reversal effect of fluvastatin therapy
    • Matsuda, N., Hayashi, Y., Takahashi, Y. and Hattori, Y. (2006). Phosphorylation of endothelial nitricoxide synthase is diminished in mesenteric arteries from septic rabbits depending on the altered phosphatidylinositol 3-kinase/Akt pathway: Reversal effect of fluvastatin therapy. J. Pharmacol. Exp. Ther. 319: 1348-1354.
    • (2006) J. Pharmacol. Exp. Ther , vol.319 , pp. 1348-1354
    • Matsuda, N.1    Hayashi, Y.2    Takahashi, Y.3    Hattori, Y.4
  • 81
    • 34548432210 scopus 로고    scopus 로고
    • Silencing of caspase-8 and caspase-3 by RNA interference prevents vascular endothelial injury in mice with endotoxic shock
    • in press
    • Matsuda, N., Takano, Y., Kageyama, S., Hatakeyama, N., Shakunaga, K., Kitajima, I., Yamazaki, M. and Hattori, Y. (2007). Silencing of caspase-8 and caspase-3 by RNA interference prevents vascular endothelial injury in mice with endotoxic shock. Cardiovasc. Res. 75: (in press).
    • (2007) Cardiovasc. Res , vol.75
    • Matsuda, N.1    Takano, Y.2    Kageyama, S.3    Hatakeyama, N.4    Shakunaga, K.5    Kitajima, I.6    Yamazaki, M.7    Hattori, Y.8
  • 85
    • 0023908652 scopus 로고
    • Enhanced vascular effects of cyclic GMP in septic rat aorta
    • McKenna, T.M. (1988). Enhanced vascular effects of cyclic GMP in septic rat aorta. Am. J. Physiol. 254: R436-R442.
    • (1988) Am. J. Physiol , vol.254
    • McKenna, T.M.1
  • 86
    • 0025353622 scopus 로고
    • Prolonged exposure of rat aorta to low levels of endotoxin in vitro results in impaired contractility. Association with vascular cytokine release
    • McKenna, T.M. (1990). Prolonged exposure of rat aorta to low levels of endotoxin in vitro results in impaired contractility. Association with vascular cytokine release. J. Clin. Invest. 86: 160-168.
    • (1990) J. Clin. Invest , vol.86 , pp. 160-168
    • McKenna, T.M.1
  • 87
    • 0022993056 scopus 로고
    • Pathology of the adult respiratory distress syndrome
    • Meyrick, B. (1986a). Pathology of the adult respiratory distress syndrome. Crit. Care Clin. 2: 405-428.
    • (1986) Crit. Care Clin , vol.2 , pp. 405-428
    • Meyrick, B.1
  • 88
    • 0022550710 scopus 로고
    • Endotoxin-induced pulmonary endothelial cell injury
    • Meyrick, B.O. (1986b). Endotoxin-induced pulmonary endothelial cell injury. Fed. Proc. 45: 19-24.
    • (1986) Fed. Proc , vol.45 , pp. 19-24
    • Meyrick, B.O.1
  • 89
    • 0030810030 scopus 로고    scopus 로고
    • Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice
    • Munoz, F.M., Hawkins, E.P., Bullard, D.C., Beaudet, A.L. and Kaplan, S.L. (1997). Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice. J. Clin. Invest. 100: 2099-2106.
    • (1997) J. Clin. Invest , vol.100 , pp. 2099-2106
    • Munoz, F.M.1    Hawkins, E.P.2    Bullard, D.C.3    Beaudet, A.L.4    Kaplan, S.L.5
  • 91
    • 0028962373 scopus 로고
    • Release of EDRF and NO in ex vivo perfused aorta: Inhibition by in vivo E. coli endotoxemia
    • Myers, P.R., Zhong, Q., Jones, J.J., Tanner, M.A., Adams, H.R. and Parker, J.L. (1995). Release of EDRF and NO in ex vivo perfused aorta: inhibition by in vivo E. coli endotoxemia. Am. J. Physiol. 268: H955-H961.
    • (1995) Am. J. Physiol , vol.268
    • Myers, P.R.1    Zhong, Q.2    Jones, J.J.3    Tanner, M.A.4    Adams, H.R.5    Parker, J.L.6
  • 92
    • 0035888676 scopus 로고    scopus 로고
    • Microcirculation in intestinal villi: A comparison between hemorrhagic and endotoxic shock
    • Nakajima, Y., Baudry, N., Duranteau, J. and Vicaut, E. (2001). Microcirculation in intestinal villi: a comparison between hemorrhagic and endotoxic shock. Am. J. Respir. Crit. Care Med. 164: 1526-1530.
    • (2001) Am. J. Respir. Crit. Care Med , vol.164 , pp. 1526-1530
    • Nakajima, Y.1    Baudry, N.2    Duranteau, J.3    Vicaut, E.4
  • 94
    • 0025764595 scopus 로고
    • Endotoxin-induced alterations in contractility of isolated vessels from sheep
    • Nelson, S., Steward, R.H., Traber, L. and Traber, D. (1991). Endotoxin-induced alterations in contractility of isolated vessels from sheep. Am. J. Physiol. 260: H1790-H1794.
    • (1991) Am. J. Physiol , vol.260
    • Nelson, S.1    Steward, R.H.2    Traber, L.3    Traber, D.4
  • 95
    • 0031985386 scopus 로고    scopus 로고
    • The systemic inflammatory response syndrome: Definitions and aetiology
    • Nyström, P.-O. (1998). The systemic inflammatory response syndrome: definitions and aetiology. J. Antimicrob. Chemother. 41 (Suppl. A): 1-7.
    • (1998) J. Antimicrob. Chemother , vol.41 , Issue.SUPPL. A , pp. 1-7
    • Nyström, P.-O.1
  • 97
    • 0033820789 scopus 로고    scopus 로고
    • Phylogenetic and functional relationships between coagulation and the innate immune response
    • Opal, S.M. (2000). Phylogenetic and functional relationships between coagulation and the innate immune response. Crit. Care Med. 28 (Suppl.): S77-S80.
    • (2000) Crit. Care Med , vol.28 , Issue.SUPPL.
    • Opal, S.M.1
  • 98
    • 0019861825 scopus 로고    scopus 로고
    • Owen, W.G. and Esmon, C.T. (1981). Functional properties of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. J. Biol. Chem. 256: 5532-5535.
    • Owen, W.G. and Esmon, C.T. (1981). Functional properties of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. J. Biol. Chem. 256: 5532-5535.
  • 99
    • 0026586461 scopus 로고
    • The role of nitric oxide in endothelial cell damage and its inhibition by glucocorticoids
    • Palmer, R.M., Bridge, L., Foxwell, N.A. and Moncada, S. (1992). The role of nitric oxide in endothelial cell damage and its inhibition by glucocorticoids. Br. J. Pharmacol. 105: 11-12.
    • (1992) Br. J. Pharmacol , vol.105 , pp. 11-12
    • Palmer, R.M.1    Bridge, L.2    Foxwell, N.A.3    Moncada, S.4
  • 100
    • 0027467022 scopus 로고
    • Selective inhibition of endothelium-dependent vasodilator capacity by Escherichia coli endotoxemia
    • Parker, J.L. and Adams, H.R. (1993). Selective inhibition of endothelium-dependent vasodilator capacity by Escherichia coli endotoxemia. Circ. Res. 72: 539-551.
    • (1993) Circ. Res , vol.72 , pp. 539-551
    • Parker, J.L.1    Adams, H.R.2
  • 102
    • 0021983890 scopus 로고
    • Cardiovascular dysfunction in septic shock: New insights into a deadly disease
    • Parrillo, J.E. (1985). Cardiovascular dysfunction in septic shock: new insights into a deadly disease. Int. J. Cardiol. 7: 314-321.
    • (1985) Int. J. Cardiol , vol.7 , pp. 314-321
    • Parrillo, J.E.1
  • 106
    • 0037303799 scopus 로고    scopus 로고
    • Mechanisms of inducible nitric oxide synthase (iNOS) inhibitor-related improvement of gut mucosal acidosis during hyperdynamic porcine endotoxemia
    • Pittner, A., Nalos, M., Asfar, P., Yang, Y., Ince, C., Georgieff, M., Bruckner, U.B., Radermacher, P. and Froba, G. (2003). Mechanisms of inducible nitric oxide synthase (iNOS) inhibitor-related improvement of gut mucosal acidosis during hyperdynamic porcine endotoxemia. Intensive Care Med. 29: 312-316.
    • (2003) Intensive Care Med , vol.29 , pp. 312-316
    • Pittner, A.1    Nalos, M.2    Asfar, P.3    Yang, Y.4    Ince, C.5    Georgieff, M.6    Bruckner, U.B.7    Radermacher, P.8    Froba, G.9
  • 107
    • 0024564509 scopus 로고
    • Human endothelial cell response to lipopolysaccharide, interleukin-1, and tumor necrosis factor is regulated by protein synthesis
    • Pohlman, T.H. and Harlan, J.M. (1989). Human endothelial cell response to lipopolysaccharide, interleukin-1, and tumor necrosis factor is regulated by protein synthesis. Cell. Immunol. 119: 41-52.
    • (1989) Cell. Immunol , vol.119 , pp. 41-52
    • Pohlman, T.H.1    Harlan, J.M.2
  • 108
    • 0141957165 scopus 로고    scopus 로고
    • Hemodynamic effects of glibenclamide during endotoxemia: Contrasting findings in vitro versus in vivo
    • Preiser, J.-C., Zhang, H., Debelle, F., Fesler, P., Kafi, S.A., Naeije, R. and Vincent, J.-L. (2003). Hemodynamic effects of glibenclamide during endotoxemia: contrasting findings in vitro versus in vivo. Shock 19: 223-228.
    • (2003) Shock , vol.19 , pp. 223-228
    • Preiser, J.-C.1    Zhang, H.2    Debelle, F.3    Fesler, P.4    Kafi, S.A.5    Naeije, R.6    Vincent, J.-L.7
  • 109
    • 0033134093 scopus 로고    scopus 로고
    • Subacute sepsis impairs vascular smooth muscle contractile machinery and alters vasoconstrictor and dilator mechanisms
    • Price, S.A., Spain, D.A., Wilson, M.A., Harris, P.D. and Garrison, R.N. (1999). Subacute sepsis impairs vascular smooth muscle contractile machinery and alters vasoconstrictor and dilator mechanisms. J. Surg. Res. 83: 75-80.
    • (1999) J. Surg. Res , vol.83 , pp. 75-80
    • Price, S.A.1    Spain, D.A.2    Wilson, M.A.3    Harris, P.D.4    Garrison, R.N.5
  • 110
    • 0034991505 scopus 로고    scopus 로고
    • Beneficial effect of glycoprotein IIb/IIIa inhibitor (AZ-1) on endothelium in Escherichia coli endotoxin-induced shock
    • Pu, Q., Wiel, E., Corseaux, D., Bordet, R., Azvin, M.A., Ezekowitz, M.D., Lund, N., Jude, B. and Vallet, B. (2001). Beneficial effect of glycoprotein IIb/IIIa inhibitor (AZ-1) on endothelium in Escherichia coli endotoxin-induced shock. Crit. Care Med. 29: 1181-1188.
    • (2001) Crit. Care Med , vol.29 , pp. 1181-1188
    • Pu, Q.1    Wiel, E.2    Corseaux, D.3    Bordet, R.4    Azvin, M.A.5    Ezekowitz, M.D.6    Lund, N.7    Jude, B.8    Vallet, B.9
  • 111
    • 0020577374 scopus 로고
    • Endothelial injury and regeneration. IV. Endotoxin: A nondenuding injury to aortic endothelium
    • Reidy, M.A. and Schwartz, S.M. (1983). Endothelial injury and regeneration. IV. Endotoxin: a nondenuding injury to aortic endothelium. Lab. Invest. 48: 25-34.
    • (1983) Lab. Invest , vol.48 , pp. 25-34
    • Reidy, M.A.1    Schwartz, S.M.2
  • 113
    • 0029836410 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase in hepatic sinusoidal endothelial cells
    • Rockey, D.C. and Chung, J.J. (1996). Regulation of inducible nitric oxide synthase in hepatic sinusoidal endothelial cells. Am. J. Physiol. 271: G260-G267.
    • (1996) Am. J. Physiol , vol.271
    • Rockey, D.C.1    Chung, J.J.2
  • 114
    • 0034689773 scopus 로고    scopus 로고
    • Role of NF-κB in p53-mediated programmed cell death
    • Ryan, K.M., Ernst, M.K., Rice, N.R. and Vousden, K.H. (2000). Role of NF-κB in p53-mediated programmed cell death. Nature 404: 892-897.
    • (2000) Nature , vol.404 , pp. 892-897
    • Ryan, K.M.1    Ernst, M.K.2    Rice, N.R.3    Vousden, K.H.4
  • 115
    • 0029034132 scopus 로고
    • Age-related decline in cytokine-induced nitric oxide synthase activation and apoptosis in cultured endothelial cells: Minimal involvement of nitric oxide in the apoptosis
    • Sato, I., Kaji, K., and Murota, S. (1995). Age-related decline in cytokine-induced nitric oxide synthase activation and apoptosis in cultured endothelial cells: minimal involvement of nitric oxide in the apoptosis. Mech. Ageing Dev. 81: 27-36.
    • (1995) Mech. Ageing Dev , vol.81 , pp. 27-36
    • Sato, I.1    Kaji, K.2    Murota, S.3
  • 117
    • 0032766506 scopus 로고    scopus 로고
    • Involvement of ATP-sensitive potassium channels in a model of a delayed vascular hyporeactivity induced by lipopolysaccharide in rats
    • Sorrentino, R., d'Emmanuele di Villa Bianca, R., Lippolis, L., Sorrentino, L., Autore, G. and Pinto, A. (1999). Involvement of ATP-sensitive potassium channels in a model of a delayed vascular hyporeactivity induced by lipopolysaccharide in rats. Br. J. Pharmacol. 127: 1447-1453.
    • (1999) Br. J. Pharmacol , vol.127 , pp. 1447-1453
    • Sorrentino, R.1    d'Emmanuele di Villa Bianca, R.2    Lippolis, L.3    Sorrentino, L.4    Autore, G.5    Pinto, A.6
  • 118
    • 0027958175 scopus 로고
    • Loss of endothelium-dependent vasodilation in the pulmonary vessels of sheep after prolonged endotoxin
    • Spath, J.A.Jr., Sloane, P.J., Gee, M.H. and Albertine, K.H. (1994). Loss of endothelium-dependent vasodilation in the pulmonary vessels of sheep after prolonged endotoxin. J. Appl. Physiol. 76: 361-369.
    • (1994) J. Appl. Physiol , vol.76 , pp. 361-369
    • Spath Jr., J.A.1    Sloane, P.J.2    Gee, M.H.3    Albertine, K.H.4
  • 121
    • 0033566808 scopus 로고    scopus 로고
    • Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways
    • Steeber, D.A., Tang, M.L., Green, N.E., Zhang, X.-Q., Sloane, J.E. and Tedder, T.F. (1999). Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways. J. Immunol. 163: 2176-2186.
    • (1999) J. Immunol , vol.163 , pp. 2176-2186
    • Steeber, D.A.1    Tang, M.L.2    Green, N.E.3    Zhang, X.-Q.4    Sloane, J.E.5    Tedder, T.F.6
  • 122
    • 0034102920 scopus 로고    scopus 로고
    • Endothelial apoptosis: Could it have a role in the pathogenesis and treatment of disease?
    • Stefanec, T. (2000). Endothelial apoptosis: could it have a role in the pathogenesis and treatment of disease? Chest 117: 841-854.
    • (2000) Chest , vol.117 , pp. 841-854
    • Stefanec, T.1
  • 123
    • 0032490670 scopus 로고    scopus 로고
    • Nuclear factor (NF)-κB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor-?-induced apoptosis
    • Stehlik, C., de Martin, R., Kumabashiri, I., Schmid, J.A., Binder, B.R. and Lipp, J. (1998). Nuclear factor (NF)-κB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor-?-induced apoptosis. J. Exp. Med. 188: 211-216.
    • (1998) J. Exp. Med , vol.188 , pp. 211-216
    • Stehlik, C.1    de Martin, R.2    Kumabashiri, I.3    Schmid, J.A.4    Binder, B.R.5    Lipp, J.6
  • 125
    • 0026515448 scopus 로고
    • In vivo and in vitro effects of endotoxin on vascular responsiveness to norepinephrine and signal transduction in the rat
    • Suba, E.A., McKenna, T.M. and Williams, T.J. (1992). In vivo and in vitro effects of endotoxin on vascular responsiveness to norepinephrine and signal transduction in the rat. Circ. Shock 36: 127-133.
    • (1992) Circ. Shock , vol.36 , pp. 127-133
    • Suba, E.A.1    McKenna, T.M.2    Williams, T.J.3
  • 126
    • 0027453626 scopus 로고
    • Differences in arterial and arteriolar endothelial structure during endotoxin shock
    • Sutton, E.T., Zhou, Z., Baker, C.H., Price, J.M. and Chen, Y. (1993). Differences in arterial and arteriolar endothelial structure during endotoxin shock. Circ. Shock 41: 71-76.
    • (1993) Circ. Shock , vol.41 , pp. 71-76
    • Sutton, E.T.1    Zhou, Z.2    Baker, C.H.3    Price, J.M.4    Chen, Y.5
  • 127
    • 0034786091 scopus 로고    scopus 로고
    • Synergistic effects of tumor necrosis factor-α and thrombin in increasing endothelial permeability
    • Tiruppathi, C., Naqvi, T., Sandoval, R., Mehta, D. and Malik, A.B. (2001). Synergistic effects of tumor necrosis factor-α and thrombin in increasing endothelial permeability. Am. J. Physiol. 281: L958-L968.
    • (2001) Am. J. Physiol , vol.281
    • Tiruppathi, C.1    Naqvi, T.2    Sandoval, R.3    Mehta, D.4    Malik, A.B.5
  • 128
    • 0032928083 scopus 로고    scopus 로고
    • Nitric oxide in septic shock
    • Titheradge, M.A. (1999). Nitric oxide in septic shock. Biochim. Biophys. Acta 1141: 437-455.
    • (1999) Biochim. Biophys. Acta , vol.1141 , pp. 437-455
    • Titheradge, M.A.1
  • 130
    • 0030875883 scopus 로고    scopus 로고
    • Adenoviral transfer of the inducible nitric oxide synthase gene blocks endothelial cell apoptosis
    • Tzeng, E., Kim, Y.M., Pitt, B.R., Lizonova, A., Kovesdi, I. and Billiar, T.R. (1997). Adenoviral transfer of the inducible nitric oxide synthase gene blocks endothelial cell apoptosis. Surgery 122: 255-263.
    • (1997) Surgery , vol.122 , pp. 255-263
    • Tzeng, E.1    Kim, Y.M.2    Pitt, B.R.3    Lizonova, A.4    Kovesdi, I.5    Billiar, T.R.6
  • 131
    • 0027137622 scopus 로고
    • Effects of endotoxin in vivo on endothelial and smooth-muscle function in rabbit and rat aorta
    • Umans, J.G., Wylam, M.E., Samsel, R.W., Edwards, J. and Schumacker, P.T. (1993). Effects of endotoxin in vivo on endothelial and smooth-muscle function in rabbit and rat aorta. Am. Rev. Respir. Dis. 148: 1638-1645.
    • (1993) Am. Rev. Respir. Dis , vol.148 , pp. 1638-1645
    • Umans, J.G.1    Wylam, M.E.2    Samsel, R.W.3    Edwards, J.4    Schumacker, P.T.5
  • 134
    • 0028852461 scopus 로고
    • Glibenclamide, a blocker of ATP-sensitive potassium channels, reverses endotoxin-induced hypotension in pigs
    • Vanelli, G., Hussain, S.N.A. and Aguggini, G. (1995). Glibenclamide, a blocker of ATP-sensitive potassium channels, reverses endotoxin-induced hypotension in pigs. Exp. Physiol. 80: 167-170.
    • (1995) Exp. Physiol , vol.80 , pp. 167-170
    • Vanelli, G.1    Hussain, S.N.A.2    Aguggini, G.3
  • 135
    • 0031000124 scopus 로고    scopus 로고
    • Cardiovascular responses to glibenclamide during endotoxaemia in the pig
    • Vanelli, G., Hussain, S.N., Dimori, M. and Aguggini, G. (1997). Cardiovascular responses to glibenclamide during endotoxaemia in the pig. Vet. Res. Commun. 21: 187-200.
    • (1997) Vet. Res. Commun , vol.21 , pp. 187-200
    • Vanelli, G.1    Hussain, S.N.2    Dimori, M.3    Aguggini, G.4
  • 136
    • 0034916215 scopus 로고    scopus 로고
    • Hemodynamic support in septic shock
    • Vincent, J.L. (2001). Hemodynamic support in septic shock. Intensive Care Med. 27 (Suppl. 1): S80-S92.
    • (2001) Intensive Care Med , vol.27 , Issue.SUPPL. 1
    • Vincent, J.L.1
  • 137
    • 0023280959 scopus 로고
    • Diminution of contractile response of the aorta from endotoxin-injected rats
    • Wakabayashi, I., Hatake, K., Kakishita, E. and Nagai, K. (1987). Diminution of contractile response of the aorta from endotoxin-injected rats. Eur. J. Pharmacol. 141: 117-122.
    • (1987) Eur. J. Pharmacol , vol.141 , pp. 117-122
    • Wakabayashi, I.1    Hatake, K.2    Kakishita, E.3    Nagai, K.4
  • 138
    • 0029750207 scopus 로고    scopus 로고
    • Heterogeneity of oxygen delivery impairs oxygen extraction by peripheral tissue: Theory
    • Walley, K.R. (1996). Heterogeneity of oxygen delivery impairs oxygen extraction by peripheral tissue: theory. Am. J. Appl. Physiol. 81: 885-894.
    • (1996) Am. J. Appl. Physiol , vol.81 , pp. 885-894
    • Walley, K.R.1
  • 140
    • 33645828012 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled crossover pilot study of a potassium channel blocker in patients with septic shock
    • Warrillow, S., Egi, M. and Bellomo, R. (2006). Randomized, double-blind, placebo-controlled crossover pilot study of a potassium channel blocker in patients with septic shock. Crit. Care Med. 34: 980-985.
    • (2006) Crit. Care Med , vol.34 , pp. 980-985
    • Warrillow, S.1    Egi, M.2    Bellomo, R.3
  • 142
    • 0033759201 scopus 로고    scopus 로고
    • Effect of L-arginine on endothelial injury and homeostasis in rabbit endotoxin shock
    • Wiel, E., Pu, Q., Corseaux, D., Robin, E., Bordet, R., Lund, N., Jude, B. and Vallet, B. (2000). Effect of L-arginine on endothelial injury and homeostasis in rabbit endotoxin shock. J. Appl. Physiol. 89: 1811-1818.
    • (2000) J. Appl. Physiol , vol.89 , pp. 1811-1818
    • Wiel, E.1    Pu, Q.2    Corseaux, D.3    Robin, E.4    Bordet, R.5    Lund, N.6    Jude, B.7    Vallet, B.8
  • 143
    • 0036775363 scopus 로고    scopus 로고
    • ATP channel inhibitors to reverse iNOS-mediated vasorelaxation
    • ATP channel inhibitors to reverse iNOS-mediated vasorelaxation. Cardiovasc. Res. 56: 154-163.
    • (2002) Cardiovasc. Res , vol.56 , pp. 154-163
    • Wilson, A.J.1    Clapp, L.H.2
  • 144
    • 28344456074 scopus 로고    scopus 로고
    • The role of endothelial cell apoptosis in inflammatory and immune diseases
    • Winn, R.K. and Harlan, J.M. (2005). The role of endothelial cell apoptosis in inflammatory and immune diseases. J. Thromb. Haemost. 3: 1815-1824.
    • (2005) J. Thromb. Haemost , vol.3 , pp. 1815-1824
    • Winn, R.K.1    Harlan, J.M.2
  • 145
    • 0031895683 scopus 로고    scopus 로고
    • Involvement and dual effects of nitric oxide in septic shock
    • Wolkow, P.P. (1998). Involvement and dual effects of nitric oxide in septic shock. Inflamn. Res. 47: 152-166.
    • (1998) Inflamn. Res , vol.47 , pp. 152-166
    • Wolkow, P.P.1
  • 146
    • 3042825358 scopus 로고    scopus 로고
    • NO and KATP channels underlie endotoxin-induced smooth muscle hyperpolarization in rat mesenteric resistance arteries
    • Wu, C.-C., Chen, S.-J. and Garland, C.J. (2004). NO and KATP channels underlie endotoxin-induced smooth muscle hyperpolarization in rat mesenteric resistance arteries. Br. J. Pharmacol. 142: 479-484.
    • (2004) Br. J. Pharmacol , vol.142 , pp. 479-484
    • Wu, C.-C.1    Chen, S.-J.2    Garland, C.J.3
  • 147
    • 0028968801 scopus 로고
    • Glibenclamide-induced inhibition of the expression of inducible nitric oxide synthase in cultured macrophages and in the anesthetized rat
    • Wu, C.-C., Thiemermann, C. and Vane, J.R. (1995). Glibenclamide-induced inhibition of the expression of inducible nitric oxide synthase in cultured macrophages and in the anesthetized rat. Br. J. Pharmacol. 114: 1273-1281.
    • (1995) Br. J. Pharmacol , vol.114 , pp. 1273-1281
    • Wu, C.-C.1    Thiemermann, C.2    Vane, J.R.3
  • 148
    • 0033201450 scopus 로고    scopus 로고
    • NF-κB activation is required for human endothelial survival during exposure to tumor necrosis factor-α but not to interleukin-1β or lipopolysaccharide
    • Zen, K., Karsan, A., Stempien-Otero, A., Yee, E., Tupper, J., Li, X., Eunson, T., Kay, M.A., Wilson, C.B., Winn, R.K. and Harlan, J.M. (1999). NF-κB activation is required for human endothelial survival during exposure to tumor necrosis factor-α but not to interleukin-1β or lipopolysaccharide. J. Biol. Chem. 274: 28808-28815.
    • (1999) J. Biol. Chem , vol.274 , pp. 28808-28815
    • Zen, K.1    Karsan, A.2    Stempien-Otero, A.3    Yee, E.4    Tupper, J.5    Li, X.6    Eunson, T.7    Kay, M.A.8    Wilson, C.B.9    Winn, R.K.10    Harlan, J.M.11
  • 149
    • 0032531208 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced NF-κB activation in human endothelial cells involves degradation of IκBα but not IκBβ
    • Zen, K., Karsan, A., Eunson, T., Yee, E. and Harlan, J.M. (1998). Lipopolysaccharide-induced NF-κB activation in human endothelial cells involves degradation of IκBα but not IκBβ. Exp. Cell. Res. 243: 425-433.
    • (1998) Exp. Cell. Res , vol.243 , pp. 425-433
    • Zen, K.1    Karsan, A.2    Eunson, T.3    Yee, E.4    Harlan, J.M.5
  • 150
    • 0032965625 scopus 로고    scopus 로고
    • Adventitia as a source of inducible nitric oxide synthase in the rat aorta
    • Zhang, H., Du, Y., Cohen, R.A., Chobanian, A.V. and Brecher, P. (1999). Adventitia as a source of inducible nitric oxide synthase in the rat aorta. Am. J. Hypertens. 12: 467-475.
    • (1999) Am. J. Hypertens , vol.12 , pp. 467-475
    • Zhang, H.1    Du, Y.2    Cohen, R.A.3    Chobanian, A.V.4    Brecher, P.5


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