Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 275, Issue 4 19-4, 1998, Pages

  Ceneviva, Gary D ^a,c   Tzeng, Edith ^a   Hoyt, Dale G ^a   Yee, Emily ^a   Gallagher, Alicia ^a   Engelhardt, John F ^b   Kim, Young Myeong ^a   Billiar, Timothy R ^a   Watkins, Simon A ^a   Pitt, Bruce R ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

Bcl 2; Cysteine protease protein 32 like protease; Heme oxygenase; Manganese superoxide dismutase; Mitochondria

Indexed keywords

CYSTEINE PROTEINASE; DITHIOTHREITOL; HEAT SHOCK PROTEIN; HEME OXYGENASE; LIPOPOLYSACCHARIDE; MANGANESE SUPEROXIDE DISMUTASE; N ACETYL S NITROSOPENICILLAMINE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; APOPTOSIS; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; GENE TRANSFER; LUNG ENDOTHELIUM; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; SHEEP; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 0000141073     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1998.275.4.l717     Document Type: Article

References (14)

1. Arcasoy, S. M., J. D. Latoche, M. Gandor, B. R. Pitt, and J. M. Pilewski. Polycations increase the efficiency of adenovirus-mediated gene transfer to epithelial and endothelial cells in vitro. Gene Ther. 4: 32-38, 1997.
2. Beauvais, F., L. Michel, and L. Dubertret. The nitric oxide donors, azide and hydroxylamine, inhibit the programmed cell death of cytokine-deprived human eosinophils. FEBS Lett. 361: 229-232, 1995.
3. Chomcynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
4. Chun, S.-Y., K. M. Eisenhauer, M. Kubo, and A. J. W. Hsueh. Interleukin-1B suppresses apoptosis in rat ovarian follicles by increasing nitric oxide production. Endocrinology 136: 3120-3127, 1995.
5. Dalton, T., R. D. Palmiter, and G. K. Andrews. Transcriptional induction of the mouse metallothionein I gene in hydrogen peroxide treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements. Nucleic Acids Res. 22: 5016-5023, 1994.
6. Dimmeler, S., J. Haendeler, M. Nehls, and A. M. Zeiher. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1-beta converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like protein. J. Exp. Med. 185: 601-608, 1997.
7. Fehsel, K., K.-D. Kroncke, K. L. Meyer, H. Huber, V. Wahn, and V. Kolb-Bachofen. Nitric oxide induces apoptosis in mouse thymocytes. J. Immunol. 155: 2858-2865, 1995.
8. Freeman, B. A., H. Gutierrez, and H. Rubbo. Nitric oxide: a central regulatory species in pulmonary oxidant reactions. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L697-L698, 1995.
9. Genaro, A. M., S. Hortelano, A. Alvarez, C. Martinez, and L. Bosca. Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. J. Clin. Invest. 95: 1884-1890, 1995.
10. Haddad, I. Y., B. R. Pitt, and S. Matalon. Mechanisms and modification of oxidant lung injury by nitric oxide. In: Pulmonary Diseases and Disorders, edited by A. P. Fishman and R. M. Senior. In press.
11. Ho, Y.-S., R. Vincent, M. S. Dey, J. W. Slot, and J. D. Crapo. Transgenic models for the study of lung antioxidant defense: enhanced manganese-containing superoxide dismutase activity gives partial protection to B6C3 hybrid mice exposed to hyperoxia. Am. J. Respir. Cell Mol. Biol. 18: 538-547, 1998.
12. Hockenberry, D. M., Z. N. Oltavi, X.-M. Yin, C. L. Milliman, and S. J. Korsmeyer. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75: 241-251, 1993.
13. Hoyt, D. G., R. J. Mannix, M. E. Gerritsen, S. C. Watkins, J. S. Lazo, and B. R. Pitt. Integrins inhibit LPS-induced DNA strand breakage in cultured lung endothelial cells. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L689-L694, 1996.
14. Hoyt, D. G., R. J. Mannix, J. M. Rusnak, B. R. Pitt, and J. S. Lazo. Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells. Am. J. Physiol. 269 (Lung Cell. Mol. Physiol. 13): L171-L177, 1995.