-
1
-
-
11444249412
-
Septic shock
-
Annane D, Bellissant E, Cavaillon JM. Septic shock. Lancet 2005; 365: 63-78. The authors present a comprehensive review of the current knowledge of septic shock pathophysiology and treatments.
-
(2005)
Lancet
, vol.365
, pp. 63-78
-
-
Annane, D.1
Bellissant, E.2
Cavaillon, J.M.3
-
2
-
-
4444225425
-
Practice parameters for hemodynamic support of sepsis in adult patients: 2004 Update
-
Hollenberg SM, Ahrens TS, Annane D, et al. Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update. Crit Care Med 2004; 32:1928-1948. These are the updated guidelines for the hemodynamic management of septic shock from a task force of the American College of Critical Care Medicine.
-
(2004)
Crit Care Med
, vol.32
, pp. 1928-1948
-
-
Hollenberg, S.M.1
Ahrens, T.S.2
Annane, D.3
-
3
-
-
3242775982
-
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
-
Dellinger RP, Carlet JM, Masur H, et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 2004; 32:858-873. The general guidelines on sepsis management from an international consortium are presented.
-
(2004)
Crit Care Med
, vol.32
, pp. 858-873
-
-
Dellinger, R.P.1
Carlet, J.M.2
Masur, H.3
-
4
-
-
4344574905
-
Science review: Mechanisms of impaired adrenal function in sepsis and molecular actions of glucocorticoids
-
Prigent H, Maxime V, Annane D. Science review: mechanisms of impaired adrenal function in sepsis and molecular actions of glucocorticoids. Crit Care 2004; 8:243-252.
-
(2004)
Crit Care
, vol.8
, pp. 243-252
-
-
Prigent, H.1
Maxime, V.2
Annane, D.3
-
5
-
-
0028283503
-
Molecular mechanisms of action of steroid/thyroid receptor superfamilly members
-
Tsai MJ, O'Malley BW. Molecular mechanisms of action of steroid/thyroid receptor superfamilly members. Annu Rev Biochem 1994; 63:889-895.
-
(1994)
Annu Rev Biochem
, vol.63
, pp. 889-895
-
-
Tsai, M.J.1
O'Malley, B.W.2
-
6
-
-
0029056558
-
Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans
-
Bamberger CM, Bamberger AM, de Castro M, Chrousos GP. Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans. J Clin Invest 1995; 95:2435-2441.
-
(1995)
J Clin Invest
, vol.95
, pp. 2435-2441
-
-
Bamberger, C.M.1
Bamberger, A.M.2
De Castro, M.3
Chrousos, G.P.4
-
7
-
-
0027172987
-
Negative transcriptional regulation of human interleukin-2 gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT
-
Paliogianni F, Raptis A, Ahuja SS, et al. Negative transcriptional regulation of human interleukin-2 gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT. J Clin Invest 1993; 91:1481-1489.
-
(1993)
J Clin Invest
, vol.91
, pp. 1481-1489
-
-
Paliogianni, F.1
Raptis, A.2
Ahuja, S.S.3
-
8
-
-
0028107237
-
Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
-
Ray A, Prefontaine KE. Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc Natl Acad Sci USA 1994; 91:752-756.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 752-756
-
-
Ray, A.1
Prefontaine, K.E.2
-
9
-
-
0028879819
-
Role of transcriptional activation of NF-kB in mediation of immunosuppression by glucocorticoids
-
Scheinman RI, Cogswell PC, Lofquist AK, Baldwin ASJ. Role of transcriptional activation of NF-kB in mediation of immunosuppression by glucocorticoids. Science 1995; 270:283-286.
-
(1995)
Science
, vol.270
, pp. 283-286
-
-
Scheinman, R.I.1
Cogswell, P.C.2
Lofquist, A.K.3
Baldwin, A.S.J.4
-
10
-
-
0028867899
-
Immunossupression by glucocorticoids: Inhibition of NF-kB activity through induction of IkB synthesis
-
Auphan N, DiDonato JA, Rosette C, et al. Immunossupression by glucocorticoids: inhibition of NF-kB activity through induction of IkB synthesis. Science 1995; 270:286-290.
-
(1995)
Science
, vol.270
, pp. 286-290
-
-
Auphan, N.1
Didonato, J.A.2
Rosette, C.3
-
11
-
-
0033916330
-
Distinct specificity for corticosteroid binding sites in amphibian cytosol, neuronal membranes, and plasma
-
Orchinik M, Matthews L, Gasser PJ. Distinct specificity for corticosteroid binding sites in amphibian cytosol, neuronal membranes, and plasma. Gen Comp Endocrinol 2000; 118:284-301.
-
(2000)
Gen Comp Endocrinol
, vol.118
, pp. 284-301
-
-
Orchinik, M.1
Matthews, L.2
Gasser, P.J.3
-
12
-
-
0031958273
-
A new hypothesis of modular glucocorticoid actions: Steroid treatment of rheumatic diseases revisited
-
Buttgereit F, Wehling M, Burmester GR. A new hypothesis of modular glucocorticoid actions: steroid treatment of rheumatic diseases revisited. Arthritis Rheum 1998; 41:761-767.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 761-767
-
-
Buttgereit, F.1
Wehling, M.2
Burmester, G.R.3
-
13
-
-
0016332640
-
Modulation of corticotrophin releasing factor release from hypothalamic synaptosomes
-
Edwardson JA, Bennett GW. Modulation of corticotrophin releasing factor release from hypothalamic synaptosomes. Nature 1974; 251:425-427.
-
(1974)
Nature
, vol.251
, pp. 425-427
-
-
Edwardson, J.A.1
Bennett, G.W.2
-
14
-
-
0035887073
-
Rapid nongenomic effect of corticosterone on neuronal nicotinic acetylcholine receptor in PC12 cells
-
Shi LJ, He HY, Liu LA, Wang CA. Rapid nongenomic effect of corticosterone on neuronal nicotinic acetylcholine receptor in PC12 cells. Arch Biochem Biophys 2001; 394:145-150.
-
(2001)
Arch Biochem Biophys
, vol.394
, pp. 145-150
-
-
Shi, L.J.1
He, H.Y.2
Liu, L.A.3
Wang, C.A.4
-
15
-
-
4344614867
-
Acute effects of a single intravenous bolus of 50-mg hydrocortisone on cardiovascular autonomic modulation in septic shock
-
Orlikowski D, Sharshar T, Castel M, Annane D. Acute effects of a single intravenous bolus of 50-mg hydrocortisone on cardiovascular autonomic modulation in septic shock. Crit Care Med 2003; 31 (suppl):A124.
-
(2003)
Crit Care Med
, vol.31
, Issue.SUPPL.
-
-
Orlikowski, D.1
Sharshar, T.2
Castel, M.3
Annane, D.4
-
16
-
-
0031722907
-
Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve
-
Annane D, Bellissant E, Sebille V, et al. Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve. Br J Clin Pharmacol 1998; 46:589-597.
-
(1998)
Br J Clin Pharmacol
, vol.46
, pp. 589-597
-
-
Annane, D.1
Bellissant, E.2
Sebille, V.3
-
17
-
-
0033829922
-
Effect of hydrocortisone on phenylephrine: Mean arterial pressure dose-response relationship in septic shock
-
Bellissant E, Annane D. Effect of hydrocortisone on phenylephrine: mean arterial pressure dose-response relationship in septic shock. Clin Pharmacol Ther 2000; 68:293-303.
-
(2000)
Clin Pharmacol Ther
, vol.68
, pp. 293-303
-
-
Bellissant, E.1
Annane, D.2
-
18
-
-
0036897343
-
Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids
-
Limbourg FP, Huang Z, Plumier JC, et al. Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids. J Clin Invest 2002; 110:1729-1738.
-
(2002)
J Clin Invest
, vol.110
, pp. 1729-1738
-
-
Limbourg, F.P.1
Huang, Z.2
Plumier, J.C.3
-
19
-
-
0036108564
-
Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase
-
Hafezi-Moghadam A, Simoncini T, Yang E, et al. Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase. Nat Med 2002; 8:473-479.
-
(2002)
Nat Med
, vol.8
, pp. 473-479
-
-
Hafezi-Moghadam, A.1
Simoncini, T.2
Yang, E.3
-
20
-
-
0026083380
-
Dexamethasone inhibits the induction of monocyte chemostatic-activating factor production by IL-1 or tumor necrosis factor
-
Mukaida N, Zachariae CC, Gusella GL, Matsushima K. Dexamethasone inhibits the induction of monocyte chemostatic-activating factor production by IL-1 or tumor necrosis factor. J Immunol 1991; 146:1212-1215.
-
(1991)
J Immunol
, vol.146
, pp. 1212-1215
-
-
Mukaida, N.1
Zachariae, C.C.2
Gusella, G.L.3
Matsushima, K.4
-
21
-
-
0029143676
-
MIF as a glucocorticoid-induced modulator of cytokine production
-
Calandra T, Bernhagen J, Metz CN, et al. MIF as a glucocorticoid-induced modulator of cytokine production. Nature 1995; 377:68-71.
-
(1995)
Nature
, vol.377
, pp. 68-71
-
-
Calandra, T.1
Bernhagen, J.2
Metz, C.N.3
-
22
-
-
0027284754
-
Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1
-
Perretti M, Flower RJ. Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1. J Immunol 1993; 150:992-999.
-
(1993)
J Immunol
, vol.150
, pp. 992-999
-
-
Perretti, M.1
Flower, R.J.2
-
23
-
-
0024268281
-
Corticosteroids suppress cyclooxygenase messenger RNA levels and prostanoid synthesis in cultured vascular cells
-
Bailey JM, Makheja AN, Pash J, Verma M. Corticosteroids suppress cyclooxygenase messenger RNA levels and prostanoid synthesis in cultured vascular cells. Biochem Biophys Res Commun 1988; 157:1159-1163.
-
(1988)
Biochem Biophys Res Commun
, vol.157
, pp. 1159-1163
-
-
Bailey, J.M.1
Makheja, A.N.2
Pash, J.3
Verma, M.4
-
24
-
-
0025672648
-
Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells
-
Radomski MW, Palmer RM, Moncada S. Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. Proc Natl Acad Sci USA 1990; 87:10043-10047.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 10043-10047
-
-
Radomski, M.W.1
Palmer, R.M.2
Moncada, S.3
-
25
-
-
0027196668
-
Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man
-
Barber AE, Coyle SM, Marano MA, et al. Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man. J Immunol 1993; 150: 1999-2006.
-
(1993)
J Immunol
, vol.150
, pp. 1999-2006
-
-
Barber, A.E.1
Coyle, S.M.2
Marano, M.A.3
-
26
-
-
0029091068
-
Influence of hypercortisolemia on soluble tumor necrosis factor receptor II and interleukin-1 receptor antagonist responses to endotoxin in human beings
-
Barber AE, Coyle SM, Fischer E, et al. Influence of hypercortisolemia on soluble tumor necrosis factor receptor II and interleukin-1 receptor antagonist responses to endotoxin in human beings. Surgery 1995; 118:406-410.
-
(1995)
Surgery
, vol.118
, pp. 406-410
-
-
Barber, A.E.1
Coyle, S.M.2
Fischer, E.3
-
27
-
-
0029842527
-
Hypercortisolemia increases plasma interleukin-10 concentrations during human endotoxemia - A clinical research center study
-
van der Poll T, Barber AE, Coyle SM, Lowry SF. Hypercortisolemia increases plasma interleukin-10 concentrations during human endotoxemia - a clinical research center study. J Clin Endocrinol Metab 1996; 81:3604-3606.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 3604-3606
-
-
Van Der Poll, T.1
Barber, A.E.2
Coyle, S.M.3
Lowry, S.F.4
-
28
-
-
0028113787
-
Low-dose hydrocortisone infusion attenuates the systemic inflammatory response syndrome. The phospholipase A2 study group
-
Briegel J, Kellermann W, Forst H, et al. Low-dose hydrocortisone infusion attenuates the systemic inflammatory response syndrome. The phospholipase A2 study group. Clin Investig 1994; 72:782-787.
-
(1994)
Clin Investig
, vol.72
, pp. 782-787
-
-
Briegel, J.1
Kellermann, W.2
Forst, H.3
-
29
-
-
0037441670
-
Immunologic and hemodynamic effects of 'low-dose' hydrocortisone in septic shock: A double-blind, randomized, placebo-controlled, crossover study
-
Keh D, Boehnke T, Weber-Cartens S, et al. Immunologic and hemodynamic effects of 'low-dose' hydrocortisone in septic shock: a double-blind, randomized, placebo-controlled, crossover study. Am J Respir Crit Care Med 2003; 167:512-520.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 512-520
-
-
Keh, D.1
Boehnke, T.2
Weber-Cartens, S.3
-
30
-
-
22044436089
-
A potential role for hydrocortisone in the positive regulation of IL-15-activated NK cell proliferation and survival
-
Mar 8; [Epub ahead of print]
-
Perez SA, Mahaira LG, Demirtzoglou FJ, et al. A potential role for hydrocortisone in the positive regulation of IL-15-activated NK cell proliferation and survival. Blood. 2005 Mar 8; [Epub ahead of print]. This is an excellent paper demonstrating that corticosteroids positively influenced the immune system by favoring the proliferation of natural killer cells.
-
(2005)
Blood
-
-
Perez, S.A.1
Mahaira, L.G.2
Demirtzoglou, F.J.3
-
31
-
-
0037151571
-
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
-
Annane D, Sebille V, Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002; 288:862-871.
-
(2002)
JAMA
, vol.288
, pp. 862-871
-
-
Annane, D.1
Sebille, V.2
Charpentier, C.3
-
32
-
-
26944433628
-
Effect of low doses of corticosteroids in septic shock-associated early acute respiratory distress syndrome
-
in press
-
Annane D, Sebille V, Bellissant E. for the Ger-Inf-05 Study Group. Effect of low doses of corticosteroids in septic shock-associated early acute respiratory distress syndrome. Crit Care Med 2005. (in press)
-
(2005)
Crit Care Med
-
-
Annane, D.1
Sebille, V.2
Bellissant, E.3
-
33
-
-
27944471374
-
Low dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock
-
in press
-
Oppert M, Schindler R, Husung C, et al. Low dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock. Crit Care Med. (in press)
-
Crit Care Med
-
-
Oppert, M.1
Schindler, R.2
Husung, C.3
-
34
-
-
11144298733
-
Corticoids normalize leukocyte production of macrophage migration inhibitory factor in septic shock
-
Maxime V, Fitting C, Annane D, Cavaillon JM. Corticoids normalize leukocyte production of macrophage migration inhibitory factor in septic shock. J Infect Dis 2005; 191:138-144. This outstanding study demonstrates that in human septic shock, corticosteroids downregulate the sepsis-associated overexpression of late mediators like MIF.
-
(2005)
J Infect Dis
, vol.191
, pp. 138-144
-
-
Maxime, V.1
Fitting, C.2
Annane, D.3
Cavaillon, J.M.4
-
35
-
-
0015406883
-
Studies on the mechanism of hydrocortisone potentiation of vasoconstrictor responses to epinephrine in the anesthetized animal
-
Yard AC, Kadowitz PJ. Studies on the mechanism of hydrocortisone potentiation of vasoconstrictor responses to epinephrine in the anesthetized animal. Eur J Pharmacol 1972; 20:1-9.
-
(1972)
Eur J Pharmacol
, vol.20
, pp. 1-9
-
-
Yard, A.C.1
Kadowitz, P.J.2
-
36
-
-
0023551157
-
Glucocorticoids modulate vascular reactivity in the rat
-
Grunfeld JP, Eloy L. Glucocorticoids modulate vascular reactivity in the rat. Hypertension 1987; 10:608-618.
-
(1987)
Hypertension
, vol.10
, pp. 608-618
-
-
Grunfeld, J.P.1
Eloy, L.2
-
37
-
-
0024993323
-
Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo
-
Thiemermann C, Vane JR. Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo. Eur J Pharmacol 1990; 182:591-595.
-
(1990)
Eur J Pharmacol
, vol.182
, pp. 591-595
-
-
Thiemermann, C.1
Vane, J.R.2
-
38
-
-
0027500926
-
Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats
-
Paya D, Gray G, Fleming I, Stoclet JC. Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats. Circ Shock 1993; 41:103-112
-
(1993)
Circ Shock
, vol.41
, pp. 103-112
-
-
Paya, D.1
Gray, G.2
Fleming, I.3
Stoclet, J.C.4
-
39
-
-
0024211517
-
Stimulation of the phosphoinositide signaling system as a possible mechanism for glucocorticoid action in blood pressure control
-
Steiner A, Vogt E, Locher R, Vetter W. Stimulation of the phosphoinositide signaling system as a possible mechanism for glucocorticoid action in blood pressure control. J Hypertens Suppl 1988; 6:S366-S368.
-
(1988)
J Hypertens Suppl
, vol.6
-
-
Steiner, A.1
Vogt, E.2
Locher, R.3
Vetter, W.4
-
40
-
-
15244344203
-
Acute effects of hydrocortisone on plasma nitrate/nitrite activity and forearm vasodilator responsiveness in normal human subjects
-
Williamson PM, Kohlhagen JL, Mangos GJ, et al. Acute effects of hydrocortisone on plasma nitrate/nitrite activity and forearm vasodilator responsiveness in normal human subjects. Clin Exp Pharmacol Physiol 2005; 32:162-166. This is an important study demonstrating that the early (within 3 hours) vascular effects of corticosteroids are not mediated through inhibition of the NO pathway.
-
(2005)
Clin Exp Pharmacol Physiol
, vol.32
, pp. 162-166
-
-
Williamson, P.M.1
Kohlhagen, J.L.2
Mangos, G.J.3
-
41
-
-
0029815998
-
Local venous responses to endotoxin in humans
-
Bhagat K, Collier J, Vallance P. Local venous responses to endotoxin in humans. Circulation 1996; 94:490-497
-
(1996)
Circulation
, vol.94
, pp. 490-497
-
-
Bhagat, K.1
Collier, J.2
Vallance, P.3
-
42
-
-
0031942028
-
Reversal of late septic shock with supraphysiologic doses of hydrocortisone
-
Bollaert PE, Charpentier C, Levy B, et al. Reversal of late septic shock with supraphysiologic doses of hydrocortisone. Crit Care Med 1998; 26: 645-650.
-
(1998)
Crit Care Med
, vol.26
, pp. 645-650
-
-
Bollaert, P.E.1
Charpentier, C.2
Levy, B.3
-
43
-
-
0032946372
-
Stress doses of hydrocortisone reverse hyperdynamic septic shock: A prospective, randomized, double-blind, single-center study
-
Briegel J, Forst H, Haller M, et al. Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med 1999; 27:723-732.
-
(1999)
Crit Care Med
, vol.27
, pp. 723-732
-
-
Briegel, J.1
Forst, H.2
Haller, M.3
-
45
-
-
4344618571
-
Corticosteroids for severe sepsis and septic shock: A systematic review and meta-analysis
-
Annane D, Bellissant E, Bollaert PE, et al. Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis. BMJ 2004; 329: 480. The authors present a meta-analysis of all randomized trials on corticosteroids for septic shock. This study demonstrated that low dose of corticosteroids improve shock duration and survival in septic shock.
-
(2004)
BMJ
, vol.329
, pp. 480
-
-
Annane, D.1
Bellissant, E.2
Bollaert, P.E.3
-
46
-
-
19944430688
-
Hydrocortisone infusion for severe community-acquired pneumonia: A preliminary randomized study
-
Confalonieri M, Urbino R, Potena A, et al. Hydrocortisone infusion for severe community-acquired pneumonia: a preliminary randomized study. Am J Respir Crit Care Med 2005; 171:242-248. This is the first randomized controlled trial demonstrating clinical benefit from low dose corticosteroids in severe community-acquired pneumonia.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 242-248
-
-
Confalonieri, M.1
Urbino, R.2
Potena, A.3
-
47
-
-
0020659555
-
Cortisol replacement in severely stressed patients
-
McKee JI, Finlay WE. Cortisol replacement in severely stressed patients. Lancet 1983; 1:484.
-
(1983)
Lancet
, vol.1
, pp. 484
-
-
McKee, J.I.1
Finlay, W.E.2
-
48
-
-
0035998343
-
Physiologic-dose steroid therapy in sepsis
-
Yildiz O, Doganay M, Aygen B, et al. Physiologic-dose steroid therapy in sepsis. Crit Care 2002; 6:251-259.
-
(2002)
Crit Care
, vol.6
, pp. 251-259
-
-
Yildiz, O.1
Doganay, M.2
Aygen, B.3
-
49
-
-
0037986631
-
Corticosteroid insufficiency in acutely ill patients
-
Annane D, Briegel J, Sprung CL. Corticosteroid insufficiency in acutely ill patients. N Engl J Med 2003; 348:2157-2159.
-
(2003)
N Engl J Med
, vol.348
, pp. 2157-2159
-
-
Annane, D.1
Briegel, J.2
Sprung, C.L.3
|