Endothelial barrier dysfunction and p42 oxidation induced by TNF-α are mediated by nitric oxide

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 272, Issue 5 16-5, 1997, Pages

  Ferro, Thomas J ^a   Gertzberg, Nancy ^a   Selden, Lynn ^a,b   Neumann, Paul ^a   Johnson, Arnold ^a,b  

^a ALBANY MEDICAL COLLEGE   (United States)

^b STRATTON VA MEDICAL CENTER   (United States)

Author keywords

Edema; Nitrotyrosine; Peroxynitrite; Reactive oxygen species; Tumor necrosis factor

Indexed keywords

NITRIC OXIDE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE;

ANIMAL CELL; ARTICLE; BLOOD VESSEL PERMEABILITY; CAPILLARY PRESSURE; CATTLE; CELL MEMBRANE PERMEABILITY; ENDOTHELIUM CELL; ENDOTOXEMIA; ENZYME INDUCTION; LUNG EDEMA; LUNG INJURY; NONHUMAN; OXIDATION; POLYCLONAL ACTIVATION; PRIORITY JOURNAL;

EID: 0030915285     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1997.272.5.l979     Document Type: Article

References (42)

1. Baydoun, A. R., P. W. Emery, J. D. Pearson, and G. E. Mann. Substrate-dependent regulation of intracellular amino acid concentrations in cultured bovine aortic endothelial cells. Biochem. Biophys. Res. Commun. 173: 940-948, 1990.
2. Beutler, B., I. W. Milsark, and A. C. Cerami. Passive immunization against cachectin/tumor necrosis factor protects mice from the lethal effect of endotoxin. Science 229: 869-871, 1985.
3. Draijer, R., D. E. Atsma, A. Van der Laarse, and V. W. Van-Hinsbergh. cGMP and nitric oxide modulate thrombin-induced endothelial permeability regulation via different pathways in human aortic and umbilical vein endothelial cells. Circ. Res. 76: 199-208, 1995.
4. Ferro, T. J., L. Selden, C. Partridge, and A. Johnson. Nitrated actin increases permeability in pulmonary arterial endothelial monolayer (PAEM) (Abstract). Am. J. Respir. Crit. Care Med. 153: A637, 1996.
5. Freeman, B. Free radical chemistry of nitric oxide: looking at the dark side. Chest 105: 79S-84S, 1994.
6. Garcia, J. G. N., and K. L. Schaphorst. Regulation of endothelial cell gap formation and paracellular permeability. J. Invest. Med. 43: 117-126, 1995.
7. Goldblum, S. E., X. Dig, and J. Camplell-Washington. TNF-α induces endothelial cell F-actin depolymerization, new actin synthesis, and barrier dysfunction. Am. J. Physiol. 264 (Cell Physiol. 33): C894-C905, 1993.
8. Haddad, I. Y., H. Ischiropoulos, B. A. Holm, J. S. Beckman, J. R. Baker, and S. Matalon. Mechanisms of peroxynitrite-induced injury to pulmonary surfactants. Am. J. Physiol. 265 (Lung Cell. Mol. Physiol. 9): L555-L564, 1993.
9. Haddad, I. Y., G. Pataki, P. Hu, C. Galliani, J. S. Beckman, and S. Matalon. Quantification of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J. Clin. Invest. 94: 2407-2413, 1994.
10. Hallows, K. B., F.-Y. Law, C. H. Packman, and P. A. Knauf. Changes in cytoskeletal actin content, F-actin distribution, and surface morphology during HL-60 cell volume regulation. J. Cell. Physiol. 167: 60-71, 1996.
11. Hocking, D. C., P. G. Phillips, T. J. Ferro, and A. Johnson. Mechanisms of pulmonary edema induced by tumor necrosis factor-α. Circ. Res. 67: 68-77, 1990.
12. Ischiropoulos, H., A. B. Al-Mehdi, and A. B. Fisher. Reactive species in ischemic rat lung injury: contribution of peroxynitrite. Am. J. Physiol. 269 (Lung Cell. Mol. Physiol. 13): L158-L164, 1995.
13. Ischiropoulos, H., L. Zhu, J. Chen, M. Tsai, J. C. Martin, C. D. Smith, and J. S. Beckman. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch. Biochem. Biophys. 298: 431-437, 1992.
14. 2. J. Clin. Invest. 89: 794-802, 1992.
15. Johnson, A., and T. J. Ferro. Nitrovasodilator repletion increases TNF-α induced pulmonary edema. J. Appl. Physiol. 80: 2151-2155, 1996.
16. Johnson, A., D. T. Phelps, and T. J. Ferro. Tumor necrosis factor-α decreases pulmonary artery endothelial nitrovasodilator via protein kinase C. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L318-L325, 1994.
17. 2. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H1012-H1022, 1989.
18. Johnson, J., B. Meyrick, G. Jesmok, and K. L. Brigham. Human recombinant tumor necrosis factor-α infusion mimics endotoxemia in sheep. J. Appl. Physiol. 66: 1448-1454, 1989.
19. Kinosian, H. J., L. A. Selden, J. E. Estes, and L. C. Gershman. Nucleotide binding to actin. Cation dependence of nucleotide dissociation and exchange rates. J. Biol. Chem. 268: 8683-8691, 1993.
20. Kooy, N. W., and J. A. Royall. Agonist-induced peroxynitrite production from endothelial cells. Arch. Biochem. Biophys. 310: 352-359, 1994.
21. Kooy, N. W., J. A. Royall, Y. Z. Ye, D. R. Kelly, and J. S. Beckman. Peroxynitrite is produced during human adult respiratory distress syndrome (Abstract). Am. J. Respir. Crit. Care Med. 149: A814, 1994.
22. Lynch, J. J., T. J. Ferro, F. A. Blumenstock, A. M. Brockenauer, and A. B. Malik. Increased endothelial permeability mediated by protein kinase C. J. Clin. Invest. 85: 1991-1998, 1990.
23. Maragos, C. M., D. Morley, D. A. Wink, T. M. Dunams, J. E. Saavedra, A. Hoffman, A. A. Bove, L. Issac, J. A. Hrabie, and L. K. Keefer. Complexes of NO with nucleophiles as agents for the controlled biological release of nitric oxide: vasorelaxants effects. J. Med. Chem. 34: 3242-3247, 1991.
24. Misko, T. P., W. M. Moore, T. P. Kasten, G. A. Nickols, J. A. Corbett, R. G. Tilton, M. L. McDaniel, J. R. Williamson, and M. G. Currie. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur. J. Pharmacol. 233: 119-125, 1993.
25. Moncada, S., M. J. Palmer, and A. Higgs. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43: 109-141, 1991.
26. Morbidelli, L., C.-H. Chang, J. G. Douglas, H. J. Granger, F. Ledda, and M. Ziche. Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H411-H415, 1996.
27. 1-proteinase inhibitor by peroxynitrite. Chem. Res. Toxicol. 5: 425-431, 1992.
28. Mulligan, M. S., J. S. Warren, C. W. Smith, D. C. Anderson, C. G. Yeh, A. R. Rudolph, and P. A. Ward. Lung injury after deposition of IgA immune complexes. J. Immunol. 148: 3086-3092, 1992.
29. Mulligan, S., J. M. Hevel, M. A. Marletta, and P. A. Ward. Tissue injury caused by deposition of immune complexes is L-arginine dependent. Proc. Natl. Acad. Sci. USA 88: 6338-6342, 1991.
30. Murphy, H. S., J. A. Shayman, G. O. Till, M. Mahrougui, C. B. Owens, U. S. Ryan, and P. A. Ward. Superoxide responses of endothelial cells to C5a and TNF: divergent signal transduction pathways. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 7): L51-L59, 1992.
31. Patterson, C. E., R. A. Rhodes, and J. G. N. Garcia. Evans blue dye as a marker of albumin clearance in cultured endothelial monolayers and isolated lung. J. Appl. Physiol. 72: 865-873, 1992.
32. Phelps, D. T., T. J. Ferro, P. J. Higgins, R. Shankar, D. M. Parker, and A. Johnson. Tumor necrosis factor-α induces the peroxynitrite-mediated depletion of lung endothelial glutathione via protein kinase C activation. Am. J. Physiol. 269 (Lung Cell. Mol. Physiol. 13): L551-L559, 1995.
33. Phillips, P. G., H. Lum, A. B. Malik, and M.-F. Tsan. Phallacidin prevents thrombin-induced increases in endothelial permeability to albumin. Am. J. Physiol. 257 (Cell Physiol. 26): C562-C567, 1989.
34. Radi, R., J. S. Beckman, K. M. Bush, and B. A. Freeman. Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem. 266: 4244-4250, 1991.
35. Radi, R., M. Rodriguez, L. Castro, and R. Telleri. Inhibition of mitochondrial electron transport by peroxynitrite. Arch. Biochem. Biophys. 308: 89-95, 1994.
36. Selden, L. A., L. C. Gershman, J. E. Estes, T. J. Ferro, and A. Johnson. Peroxynitrite-induced tyrosine nitration mediates decreased polymerization of actin (Abstract). Mol. Biol. Cell 6:20A, 1995.
37. Sheterline, P., and J. C. Sparrow. Actin. Protein Profiles 1: 1-121, 1994.
38. Steel, R. G. D., and J. H. Torrie. Principles and Procedures of Statistics: A Biomedical Approach (2nd ed.). New York: McGraw-Hill, 1980, p. 173-177.
39. Suttorp, N., S. Hippenstiel, M. Fuhrmann, M. Krull, and T. Podzuweit. Role of nitric oxide and phosphodiesterase isoenzyme II for reduction of endothelial hyperpermeablity. Am. J. Physiol. 270 (Cell Physiol. 39): C778-C785, 1996.
40. Szabo, C., B. Zingarelli, and A. Salzman. Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite. Circ. Res. 78: 1051-1063, 1996.
41. Tracey, K. J., S. F. Lowry, and A. Cerami. Cachectin/TNF in septic shock and septic adult respiratory distress syndrome. Am. Rev. Respir. Dis. 138: 1377-1379, 1988.
42. Tsao, F. H., X. Chen, X. Chen, and V. X. Vu. Immunocharacterization and developmental regulation of rabbit lung calcium dependent phospholipid-binding proteins. Biochim. Biophys. Acta 1213: 91-99, 1994.