-
1
-
-
2642526164
-
VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
-
Azzouz M., Ralph G.S., Storkebaum E., Walmsley L.E., Mitrophanous K.A., Kingsman S.M., Carmeliet P., and Mazarakis N.D. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 429 (2004) 413-417
-
(2004)
Nature
, vol.429
, pp. 413-417
-
-
Azzouz, M.1
Ralph, G.S.2
Storkebaum, E.3
Walmsley, L.E.4
Mitrophanous, K.A.5
Kingsman, S.M.6
Carmeliet, P.7
Mazarakis, N.D.8
-
2
-
-
25844496913
-
Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis
-
Baron P., Bussini S., Cardin V., Corbo M., Conti G., Galimberti D., Scarpini E., Bresolin N., Wharton S.B., Shaw P.J., and Silani V. Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis. Muscle Nerve 32 (2005) 541-544
-
(2005)
Muscle Nerve
, vol.32
, pp. 541-544
-
-
Baron, P.1
Bussini, S.2
Cardin, V.3
Corbo, M.4
Conti, G.5
Galimberti, D.6
Scarpini, E.7
Bresolin, N.8
Wharton, S.B.9
Shaw, P.J.10
Silani, V.11
-
3
-
-
0030584891
-
Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat
-
Berman J.W., Guida M.P., Warren J., Amat J., and Brosnan C.F. Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat. J. Immunol. 156 (1996) 3017-3023
-
(1996)
J. Immunol.
, vol.156
, pp. 3017-3023
-
-
Berman, J.W.1
Guida, M.P.2
Warren, J.3
Amat, J.4
Brosnan, C.F.5
-
4
-
-
33744798774
-
Onset and progression in inherited ALS determined by motor neurons and microglia
-
Boillee S., Yamanaka K., Lobsiger C.S., Copeland N.G., Jenkins N.A., Kassiotis G., Kollias G., and Cleveland D.W. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 312 (2006) 1389-1392
-
(2006)
Science
, vol.312
, pp. 1389-1392
-
-
Boillee, S.1
Yamanaka, K.2
Lobsiger, C.S.3
Copeland, N.G.4
Jenkins, N.A.5
Kassiotis, G.6
Kollias, G.7
Cleveland, D.W.8
-
5
-
-
17444419749
-
ß-Amyloid 42 accumulation in the lumbar spinal cord motor neurons of amyotrophic lateral sclerosis patients
-
Calingasan N.Y., Chen J., Kiaei M., and Beal M.F. ß-Amyloid 42 accumulation in the lumbar spinal cord motor neurons of amyotrophic lateral sclerosis patients. Neurobiol. Dis. 19 (2005) 340-347
-
(2005)
Neurobiol. Dis.
, vol.19
, pp. 340-347
-
-
Calingasan, N.Y.1
Chen, J.2
Kiaei, M.3
Beal, M.F.4
-
6
-
-
0035516124
-
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
-
Cleveland D.W., and Rothstein J.D. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat. Rev. Neurosci. 2 (2001) 806-819
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
7
-
-
0030810926
-
X-linked IAP is a direct inhibitor of cell-death proteases
-
Deveraux Q.L., Takahashi R., Salvesen G.S., and Reed J.C. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388 (1997) 300-304
-
(1997)
Nature
, vol.388
, pp. 300-304
-
-
Deveraux, Q.L.1
Takahashi, R.2
Salvesen, G.S.3
Reed, J.C.4
-
8
-
-
34247473080
-
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
-
Di Giorgio F.P., Carrasco M.A., Siao M.C., Maniatis T., and Eggan K. Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nat. Neurosci. 10 (2007) 608-614
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 608-614
-
-
Di Giorgio, F.P.1
Carrasco, M.A.2
Siao, M.C.3
Maniatis, T.4
Eggan, K.5
-
9
-
-
0001517943
-
Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons
-
Ebens A., Brose K., Leonardo E.D., Hanson Jr. M.G., Bladt F., Birchmeier C., Barres B.A., and Tessier-Lavigne M. Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons. Neuron 17 (1996) 1157-1172
-
(1996)
Neuron
, vol.17
, pp. 1157-1172
-
-
Ebens, A.1
Brose, K.2
Leonardo, E.D.3
Hanson Jr., M.G.4
Bladt, F.5
Birchmeier, C.6
Barres, B.A.7
Tessier-Lavigne, M.8
-
10
-
-
1842407161
-
Inhibition of ICE slows ALS in mice
-
Friedlander R.M., Brown R.H., Gagliardini V., Wang J., and Yuan J. Inhibition of ICE slows ALS in mice. Nature 388 (1997) 31
-
(1997)
Nature
, vol.388
, pp. 31
-
-
Friedlander, R.M.1
Brown, R.H.2
Gagliardini, V.3
Wang, J.4
Yuan, J.5
-
11
-
-
0029024336
-
Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons
-
Funakoshi H., Belluardo N., Arenas E., Yamamoto Y., Casabona A., Persson H., and Ibanez C.F. Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. Science 268 (1995) 1495-1499
-
(1995)
Science
, vol.268
, pp. 1495-1499
-
-
Funakoshi, H.1
Belluardo, N.2
Arenas, E.3
Yamamoto, Y.4
Casabona, A.5
Persson, H.6
Ibanez, C.F.7
-
12
-
-
0032574739
-
Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons
-
Funakoshi H., Risling M., Carlstedt T., Lendahl U., Timmusk T., Metsis M., Yamamoto Y., and Ibanez C.F. Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 5269-5274
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 5269-5274
-
-
Funakoshi, H.1
Risling, M.2
Carlstedt, T.3
Lendahl, U.4
Timmusk, T.5
Metsis, M.6
Yamamoto, Y.7
Ibanez, C.F.8
-
13
-
-
0037212712
-
Hepatocyte growth factor: from diagnosis to clinical applications
-
Funakoshi H., and Nakamura T. Hepatocyte growth factor: from diagnosis to clinical applications. Clin. Chim. Acta 327 (2003) 1-23
-
(2003)
Clin. Chim. Acta
, vol.327
, pp. 1-23
-
-
Funakoshi, H.1
Nakamura, T.2
-
14
-
-
0023772364
-
Interleukin-1 injected into mammalian brain stimulates astrocytosis and neovascularization
-
Giulian D., Woodward J., Young D.G., Krebs J.F., and Lachman L.B. Interleukin-1 injected into mammalian brain stimulates astrocytosis and neovascularization. J. Neurosci. 8 (1988) 2485-2490
-
(1988)
J. Neurosci.
, vol.8
, pp. 2485-2490
-
-
Giulian, D.1
Woodward, J.2
Young, D.G.3
Krebs, J.F.4
Lachman, L.B.5
-
15
-
-
15444362469
-
Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant kidney by modulating tubular expression of macrophage chemoattractant protein-1 and RANTES
-
Gong R., Rifai A., Tolbert E.M., Biswas P., Centracchio J.N., and Dworkin L.D. Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant kidney by modulating tubular expression of macrophage chemoattractant protein-1 and RANTES. J. Am. Soc. Nephrol. 15 (2004) 2868-2881
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 2868-2881
-
-
Gong, R.1
Rifai, A.2
Tolbert, E.M.3
Biswas, P.4
Centracchio, J.N.5
Dworkin, L.D.6
-
16
-
-
0035437866
-
Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis
-
Guegan C., Vila M., Rosoklija G., Hays A.P., and Przedborski S. Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis. J. Neurosci. 21 (2001) 6569-6576
-
(2001)
J. Neurosci.
, vol.21
, pp. 6569-6576
-
-
Guegan, C.1
Vila, M.2
Rosoklija, G.3
Hays, A.P.4
Przedborski, S.5
-
17
-
-
2342614295
-
Local GDNF expression mediated by lentiviral vector protects facial nerve motor neurons but not spinal motor neurons in SOD1(G93A) transgenic mice
-
Guillot S., Azzouz M., Deglon N., Zurn A., and Aebischer P. Local GDNF expression mediated by lentiviral vector protects facial nerve motor neurons but not spinal motor neurons in SOD1(G93A) transgenic mice. Neurobiol. Dis. 16 (2004) 139-149
-
(2004)
Neurobiol. Dis.
, vol.16
, pp. 139-149
-
-
Guillot, S.1
Azzouz, M.2
Deglon, N.3
Zurn, A.4
Aebischer, P.5
-
18
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
-
Gurney M.E., Pu H., Chiu A.Y., Dal Canto M.C., Polchow C.Y., Alexander D.D., Caliendo J., Hentati A., Kwon Y.W., Deng H.X., Chen W., Zhai P., Sufit R.L., and Siddique T. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 264 (1994) 1772-1775
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.X.10
Chen, W.11
Zhai, P.12
Sufit, R.L.13
Siddique, T.14
-
19
-
-
10744229158
-
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
-
Henkel J.S., Engelhardt J.I., Siklos L., Simpson E.P., Kim S.H., Pan T., Goodman J.C., Siddique T., Beers D.R., and Appel S.H. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann. Neurol. 55 (2004) 221-235
-
(2004)
Ann. Neurol.
, vol.55
, pp. 221-235
-
-
Henkel, J.S.1
Engelhardt, J.I.2
Siklos, L.3
Simpson, E.P.4
Kim, S.H.5
Pan, T.6
Goodman, J.C.7
Siddique, T.8
Beers, D.R.9
Appel, S.H.10
-
20
-
-
33644821966
-
The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS
-
Henkel J.S., Beers D.R., Siklos L., and Appel S.H. The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS. Mol. Cell. Neurosci. 31 (2006) 427-437
-
(2006)
Mol. Cell. Neurosci.
, vol.31
, pp. 427-437
-
-
Henkel, J.S.1
Beers, D.R.2
Siklos, L.3
Appel, S.H.4
-
21
-
-
0034810795
-
Interleukin-1ß is required for the early evolution of reactive astrocytosis following CNS lesion
-
Herx L.M., and Yong V.W. Interleukin-1ß is required for the early evolution of reactive astrocytosis following CNS lesion. J. Neuropathol. Exp. Neurol. 60 (2001) 961-971
-
(2001)
J. Neuropathol. Exp. Neurol.
, vol.60
, pp. 961-971
-
-
Herx, L.M.1
Yong, V.W.2
-
22
-
-
0029142780
-
Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: implication as neurotrophic factor
-
Honda S., Kagoshima M., Wanaka A., Tohyama M., Matsumoto K., and Nakamura T. Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: implication as neurotrophic factor. Brain Res. Mol. Brain Res. 32 (1995) 197-210
-
(1995)
Brain Res. Mol. Brain Res.
, vol.32
, pp. 197-210
-
-
Honda, S.1
Kagoshima, M.2
Wanaka, A.3
Tohyama, M.4
Matsumoto, K.5
Nakamura, T.6
-
23
-
-
0034744513
-
Interleukin-1ß converting enzyme/Caspase-1 (ICE/Caspase-1) and soluble APO-1/Fas/CD 95 receptor in amyotrophic lateral sclerosis patients
-
Ilzecka J., Stelmasiak Z., and Dobosz B. Interleukin-1ß converting enzyme/Caspase-1 (ICE/Caspase-1) and soluble APO-1/Fas/CD 95 receptor in amyotrophic lateral sclerosis patients. Acta Neurol. Scand. 103 (2001) 255-258
-
(2001)
Acta Neurol. Scand.
, vol.103
, pp. 255-258
-
-
Ilzecka, J.1
Stelmasiak, Z.2
Dobosz, B.3
-
24
-
-
0030601207
-
A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage
-
Imai Y., Ibata I., Ito D., Ohsawa K., and Kohsaka S. A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biochem. Biophys. Res. Commun. 224 (1996) 855-862
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.224
, pp. 855-862
-
-
Imai, Y.1
Ibata, I.2
Ito, D.3
Ohsawa, K.4
Kohsaka, S.5
-
25
-
-
10744223086
-
The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model
-
Inoue H., Tsukita K., Iwasato T., Suzuki Y., Tomioka M., Tateno M., Nagao M., Kawata A., Saido T.C., Miura M., Misawa H., Itohara S., and Takahashi R. The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model. EMBO J. 22 (2003) 6665-6674
-
(2003)
EMBO J.
, vol.22
, pp. 6665-6674
-
-
Inoue, H.1
Tsukita, K.2
Iwasato, T.3
Suzuki, Y.4
Tomioka, M.5
Tateno, M.6
Nagao, M.7
Kawata, A.8
Saido, T.C.9
Miura, M.10
Misawa, H.11
Itohara, S.12
Takahashi, R.13
-
26
-
-
19944432585
-
Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis
-
Jiang Y.M., Yamamoto M., Kobayashi Y., Yoshihara T., Liang Y., Terao S., Takeuchi H., Ishigaki S., Katsuno M., Adachi H., Niwa J., Tanaka F., Doyu M., Yoshida M., Hashizume Y., and Sobue G. Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis. Ann. Neurol. 57 (2005) 236-251
-
(2005)
Ann. Neurol.
, vol.57
, pp. 236-251
-
-
Jiang, Y.M.1
Yamamoto, M.2
Kobayashi, Y.3
Yoshihara, T.4
Liang, Y.5
Terao, S.6
Takeuchi, H.7
Ishigaki, S.8
Katsuno, M.9
Adachi, H.10
Niwa, J.11
Tanaka, F.12
Doyu, M.13
Yoshida, M.14
Hashizume, Y.15
Sobue, G.16
-
27
-
-
1642407666
-
Interleukin-1ß induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis
-
John G.R., Chen L., Rivieccio M.A., Melendez-Vasquez C.V., Hartley A., and Brosnan C.F. Interleukin-1ß induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis. J. Neurosci. 24 (2004) 2837-2845
-
(2004)
J. Neurosci.
, vol.24
, pp. 2837-2845
-
-
John, G.R.1
Chen, L.2
Rivieccio, M.A.3
Melendez-Vasquez, C.V.4
Hartley, A.5
Brosnan, C.F.6
-
28
-
-
0042528664
-
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
-
Kaspar B.K., Llado J., Sherkat N., Rothstein J.D., and Gage F.H. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 301 (2003) 839-842
-
(2003)
Science
, vol.301
, pp. 839-842
-
-
Kaspar, B.K.1
Llado, J.2
Sherkat, N.3
Rothstein, J.D.4
Gage, F.H.5
-
29
-
-
0037593236
-
Expression of hepatocyte growth factor and c-Met in the anterior horn cells of the spinal cord in the patients with amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS and familial ALS with superoxide dismutase 1 gene mutation
-
Kato S., Funakoshi H., Nakamura T., Kato M., Nakano I., Hirano A., and Ohama E. Expression of hepatocyte growth factor and c-Met in the anterior horn cells of the spinal cord in the patients with amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS and familial ALS with superoxide dismutase 1 gene mutation. Acta Neuropathol. 106 (2003) 112-120
-
(2003)
Acta Neuropathol.
, vol.106
, pp. 112-120
-
-
Kato, S.1
Funakoshi, H.2
Nakamura, T.3
Kato, M.4
Nakano, I.5
Hirano, A.6
Ohama, E.7
-
30
-
-
0035896440
-
Intrathecal cyclosporin prolongs survival of late-stage ALS mice
-
Keep M., Elmer E., Fong K.S., and Csiszar K. Intrathecal cyclosporin prolongs survival of late-stage ALS mice. Brain Res. 894 (2001) 327-331
-
(2001)
Brain Res.
, vol.894
, pp. 327-331
-
-
Keep, M.1
Elmer, E.2
Fong, K.S.3
Csiszar, K.4
-
31
-
-
0030756459
-
Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Kostic V., Jackson-Lewis V., de Bilbao F., Dubois-Dauphin M., and Przedborski S. Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science 277 (1997) 559-562
-
(1997)
Science
, vol.277
, pp. 559-562
-
-
Kostic, V.1
Jackson-Lewis, V.2
de Bilbao, F.3
Dubois-Dauphin, M.4
Przedborski, S.5
-
32
-
-
0036406903
-
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis
-
Kriz J., Nguyen M.D., and Julien J.P. Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiol. Dis. 10 (2002) 268-278
-
(2002)
Neurobiol. Dis.
, vol.10
, pp. 268-278
-
-
Kriz, J.1
Nguyen, M.D.2
Julien, J.P.3
-
33
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
Li M., Ona V.O., Guegan C., Chen M., Jackson-Lewis V., Andrews L.J., Olszewski A.J., Stieg P.E., Lee J.P., Przedborski S., and Friedlander R.M. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 288 (2000) 335-339
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
Ona, V.O.2
Guegan, C.3
Chen, M.4
Jackson-Lewis, V.5
Andrews, L.J.6
Olszewski, A.J.7
Stieg, P.E.8
Lee, J.P.9
Przedborski, S.10
Friedlander, R.M.11
-
34
-
-
0041864076
-
Cytokine, chemokine and growth factor gene profiling of cultured human astrocytes after exposure to proinflammatory stimuli
-
Meeuwsen S., Persoon-Deen C., Bsibsi M., Ravid R., and van Noort J.M. Cytokine, chemokine and growth factor gene profiling of cultured human astrocytes after exposure to proinflammatory stimuli. Glia 43 (2003) 243-253
-
(2003)
Glia
, vol.43
, pp. 243-253
-
-
Meeuwsen, S.1
Persoon-Deen, C.2
Bsibsi, M.3
Ravid, R.4
van Noort, J.M.5
-
35
-
-
17044368875
-
X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO
-
Morizane Y., Honda R., Fukami K., and Yasuda H. X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO. J. Biochem. (Tokyo) 137 (2005) 125-132
-
(2005)
J. Biochem. (Tokyo)
, vol.137
, pp. 125-132
-
-
Morizane, Y.1
Honda, R.2
Fukami, K.3
Yasuda, H.4
-
36
-
-
34247475338
-
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
-
Nagai M., Re D.B., Nagata T., Chalazonitis A., Jessell T.M., Wichterle H., and Przedorski S. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat. Neurosci. 10 (2007) 615-622
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 615-622
-
-
Nagai, M.1
Re, D.B.2
Nagata, T.3
Chalazonitis, A.4
Jessell, T.M.5
Wichterle, H.6
Przedorski, S.7
-
37
-
-
0021285134
-
Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
-
Nakamura T., Nawa K., and Ichihara A. Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem. Biophys. Res. Commun. 122 (1984) 1450-1459
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.122
, pp. 1450-1459
-
-
Nakamura, T.1
Nawa, K.2
Ichihara, A.3
-
38
-
-
0024427178
-
Molecular cloning and expression of human hepatocyte growth factor
-
Nakamura T., Nishizawa T., Hagiya M., Seki T., Shimonishi M., Sugimura A., Tashiro K., and Shimizu S. Molecular cloning and expression of human hepatocyte growth factor. Nature 342 (1989) 440-443
-
(1989)
Nature
, vol.342
, pp. 440-443
-
-
Nakamura, T.1
Nishizawa, T.2
Hagiya, M.3
Seki, T.4
Shimonishi, M.5
Sugimura, A.6
Tashiro, K.7
Shimizu, S.8
-
39
-
-
0033999093
-
Hepatocyte growth factor/scatter factor is a neurotrophic survival factor for lumbar but not for other somatic motor neurons in the chick embryo
-
Novak K.D., Prevette D., Wang S., Gould T.W., and Oppenheim R.W. Hepatocyte growth factor/scatter factor is a neurotrophic survival factor for lumbar but not for other somatic motor neurons in the chick embryo. J. Neurosci. 20 (2000) 326-337
-
(2000)
J. Neurosci.
, vol.20
, pp. 326-337
-
-
Novak, K.D.1
Prevette, D.2
Wang, S.3
Gould, T.W.4
Oppenheim, R.W.5
-
40
-
-
0034610328
-
Caspase-1 and -3 are sequentially activated in motor neuron death in Cu, Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis
-
Pasinelli P., Houseweart M.K., Brown Jr. R.H., and Cleveland D.W. Caspase-1 and -3 are sequentially activated in motor neuron death in Cu, Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 13901-13906
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13901-13906
-
-
Pasinelli, P.1
Houseweart, M.K.2
Brown Jr., R.H.3
Cleveland, D.W.4
-
41
-
-
33747605320
-
Molecular biology of amyotrophic lateral sclerosis: insights from genetics
-
Pasinelli P., and Brown Jr. R.H. Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat. Rev. Neurosci. 7 (2006) 710-723
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 710-723
-
-
Pasinelli, P.1
Brown Jr., R.H.2
-
42
-
-
0037381513
-
Adenoviral gene transfer of GDNF, BDNF and TGF beta 2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motor neurons after facial nerve avulsion
-
Sakamoto T., Kawazoe Y., Shen J.S., Takeda Y., Arakawa Y., Ogawa J., Oyanagi K., Ohashi T., Watanabe K., Inoue K., Eto Y., and Watabe K. Adenoviral gene transfer of GDNF, BDNF and TGF beta 2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motor neurons after facial nerve avulsion. J. Neurosci. Res. 72 (2003) 54-64
-
(2003)
J. Neurosci. Res.
, vol.72
, pp. 54-64
-
-
Sakamoto, T.1
Kawazoe, Y.2
Shen, J.S.3
Takeda, Y.4
Arakawa, Y.5
Ogawa, J.6
Oyanagi, K.7
Ohashi, T.8
Watanabe, K.9
Inoue, K.10
Eto, Y.11
Watabe, K.12
-
43
-
-
0027070473
-
Brain-derived neurotrophic factor prevents the death of motor neurons in newborn rats after nerve section
-
Sendtner M., Holtmann B., Kolbeck R., Thoenen H., and Barde Y.A. Brain-derived neurotrophic factor prevents the death of motor neurons in newborn rats after nerve section. Nature 360 (1992) 757-759
-
(1992)
Nature
, vol.360
, pp. 757-759
-
-
Sendtner, M.1
Holtmann, B.2
Kolbeck, R.3
Thoenen, H.4
Barde, Y.A.5
-
44
-
-
3343011970
-
Caspase activation, inhibition, and reactivation: a mechanistic view
-
Shi Y. Caspase activation, inhibition, and reactivation: a mechanistic view. Protein Sci. 13 (2004) 1979-1987
-
(2004)
Protein Sci.
, vol.13
, pp. 1979-1987
-
-
Shi, Y.1
-
45
-
-
0036703771
-
Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS
-
Sun W., Funakoshi H., and Nakamura T. Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS. J. Neurosci. 22 (2002) 6537-6548
-
(2002)
J. Neurosci.
, vol.22
, pp. 6537-6548
-
-
Sun, W.1
Funakoshi, H.2
Nakamura, T.3
-
46
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1ß processing in monocytes
-
Thornberry N.A., Bull H.G., Calaycay J.R., Chapman K.T., Howard A.D., Kostura M.J., Miller D.K., Molineaux S.M., Weidner J.R., Aunins J., Elliston K.O., Ayala J.M., Casano F.J., Chin J., Ding G.J.F., Egger L.A., Gaffney E.P., Limjuco G., Palyha O.C., Raju S.M., Rolando A.M., Salley J.P., Yamin T.-T., Lee T.D., Shively J.E., MacCross M., Mumford R.A., Schmidt J.A., and Tocci M.J. A novel heterodimeric cysteine protease is required for interleukin-1ß processing in monocytes. Nature 356 (1992) 768-774
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
Elliston, K.O.11
Ayala, J.M.12
Casano, F.J.13
Chin, J.14
Ding, G.J.F.15
Egger, L.A.16
Gaffney, E.P.17
Limjuco, G.18
Palyha, O.C.19
Raju, S.M.20
Rolando, A.M.21
Salley, J.P.22
Yamin, T.-T.23
Lee, T.D.24
Shively, J.E.25
MacCross, M.26
Mumford, R.A.27
Schmidt, J.A.28
Tocci, M.J.29
more..
-
47
-
-
0037067009
-
Minocycline delays disease onset and mortality in a transgenic model of ALS
-
Van Den Bosch L., Tilkin P., Lemmens G., and Robberecht W. Minocycline delays disease onset and mortality in a transgenic model of ALS. Neuroreport 13 (2002) 1067-1070
-
(2002)
Neuroreport
, vol.13
, pp. 1067-1070
-
-
Van Den Bosch, L.1
Tilkin, P.2
Lemmens, G.3
Robberecht, W.4
-
48
-
-
0037104725
-
Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis
-
Wang L.J., Lu Y.Y., Muramatsu S., Ikeguchi K., Fujimoto K., Okada T., Mizukami H., Matsushita T., Hanazono Y., Kume A., Nagatsu T., Ozawa K., and Nakano I. Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis. J. Neurosci. 22 (2002) 6920-6928
-
(2002)
J. Neurosci.
, vol.22
, pp. 6920-6928
-
-
Wang, L.J.1
Lu, Y.Y.2
Muramatsu, S.3
Ikeguchi, K.4
Fujimoto, K.5
Okada, T.6
Mizukami, H.7
Matsushita, T.8
Hanazono, Y.9
Kume, A.10
Nagatsu, T.11
Ozawa, K.12
Nakano, I.13
-
49
-
-
9144230806
-
Increased cytotoxic potential of microglia from ALS-transgenic mice
-
Weydt P., Yuen E.C., Ransom B.R., and Moller T. Increased cytotoxic potential of microglia from ALS-transgenic mice. GLIA 48 (2004) 179-182
-
(2004)
GLIA
, vol.48
, pp. 179-182
-
-
Weydt, P.1
Yuen, E.C.2
Ransom, B.R.3
Moller, T.4
-
50
-
-
34548233140
-
Mutant SOD1G93A microglia are more neurotoxic relative to wild-type microglia
-
Xiao Q., Zhao W., Beers D.R., Yen A.A., Xie W., Henkel J.S., and Appel S.H. Mutant SOD1G93A microglia are more neurotoxic relative to wild-type microglia. J. Neurochem. 102 (2007) 2008-2019
-
(2007)
J. Neurochem.
, vol.102
, pp. 2008-2019
-
-
Xiao, Q.1
Zhao, W.2
Beers, D.R.3
Yen, A.A.4
Xie, W.5
Henkel, J.S.6
Appel, S.H.7
-
51
-
-
0030865088
-
Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motor neurons
-
Yamamoto Y., Livet J., Pollock R.A., Garces A., Arce V., deLapeyriere O., and Henderson C.E. Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motor neurons. Development 124 (1997) 2903-2913
-
(1997)
Development
, vol.124
, pp. 2903-2913
-
-
Yamamoto, Y.1
Livet, J.2
Pollock, R.A.3
Garces, A.4
Arce, V.5
deLapeyriere, O.6
Henderson, C.E.7
-
52
-
-
0033539522
-
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
-
Yrjanheikki J., Tikka T., Keinanen R., Goldsteins G., Chan P.H., and Koistinaho J. A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 13496-13500
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13496-13500
-
-
Yrjanheikki, J.1
Tikka, T.2
Keinanen, R.3
Goldsteins, G.4
Chan, P.H.5
Koistinaho, J.6
-
53
-
-
0037007645
-
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
-
Zhu S., Stavrovskaya I.G., Drozda M., Kim B.Y., Ona V., Li M., Sarang S., Liu A.S., Hartley D.M., Wu D.C., Gullans S., Ferrante R.J., Przedborski S., Kristal B.S., and Friedlander R.M. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature 417 (2002) 74-78
-
(2002)
Nature
, vol.417
, pp. 74-78
-
-
Zhu, S.1
Stavrovskaya, I.G.2
Drozda, M.3
Kim, B.Y.4
Ona, V.5
Li, M.6
Sarang, S.7
Liu, A.S.8
Hartley, D.M.9
Wu, D.C.10
Gullans, S.11
Ferrante, R.J.12
Przedborski, S.13
Kristal, B.S.14
Friedlander, R.M.15
|