West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis

Journal of Virology

Volumn 81, Issue 20, 2007, Pages 10849-10860

  Medigeshi, Guruprasad R ^a   Lancaster, Alissa M ^a   Hirsch, Alec J ^a   Briese, Thomas ^b   Lipkin, W Ian ^b   DeFilippis, Victor ^a   Früh, Klaus ^a   Mason, Peter W ^c   Nikolich Zugich, Janko ^a   Nelson, Jay A ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Mailman School of Public Health of Columbia University ^*  (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; BINDING PROTEIN; CASPASE 12; CASPASE 3; CYCLIC AMP RESPONSE ELEMENT BINDING TRANSCRIPTION FACTOR HOMOLOGOUS PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; INITIATION FACTOR 2ALPHA; INOSITOL REQUIRING ENZYME 1 DEPENDENT SPLICING OF X BOX BINDING PROTEIN 1; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NONSTRUCTURAL PROTEIN; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 5A; PROTEASOME; PROTEIN KINASE R; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRESS; CONTROLLED STUDY; DNA DAMAGE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME DEGRADATION; GENE INDUCTION; GENE TARGETING; HIPPOCAMPUS; MOLECULAR MECHANICS; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; TRANSCRIPTION REGULATION; VIRUS ENCEPHALITIS; VIRUS INFECTION; VIRUS MENINGITIS; VIRUS PATHOGENESIS; WEST NILE FLAVIVIRUS;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; APOPTOSIS; CELL LINE; DNA-BINDING PROTEINS; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; HUMANS; MICE; NEURONS; NUCLEAR PROTEINS; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP; VIRUS REPLICATION; WEST NILE FEVER; WEST NILE VIRUS;

EUKARYOTA; RATTUS; WEST NILE VIRUS;

EID: 35148894008     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01151-07     Document Type: Article

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