Methods for Identifying Novel Integrin Ligands

Methods in Enzymology

Volumn 426, Issue , 2007, Pages 223-237

  Marciano, Denise K ^a,c   Denda, Sumiko ^b   Reichardt, Louis F ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SHISEIDO RESEARCH CENTER   (Japan)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; HETERODIMER; INTEGRIN; INTEGRIN RECEPTOR; LIGAND;

ANALYTIC METHOD; ANIMAL CELL; ANTIBODY LABELING; CELL INTERACTION; EMBRYO; EXTRACELLULAR MATRIX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PURIFICATION; RECEPTOR BINDING; REGULATORY MECHANISM; REVIEW; WESTERN BLOTTING; ANIMAL; HUMAN; METABOLISM;

ANIMALS; HUMANS; INTEGRINS; LIGANDS;

EID: 35148814901     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(07)26011-2     Document Type: Review

References (48)

1. Brandenberger R., Schmidt A., Linton J., Wang D., Backus C., Denda S., Müller U., and Reichardt L.F. Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney. J. Cell Biol. 154 (2001) 447-458
2. Chan C.S., Weeber E.J., Kurup S., Sweatt J.D., and Davis R.L. Integrin requirement for hippocampal synaptic plasticity and spatial memory. J. Neurosci. 23 (2003) 7107-7116
3. Chattopadhyay N., Wang Z., Ashman L.K., Brady-Kalnay S.M., and Kreidberg J.A. alpha3beta1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPmu expression and cell-cell adhesion. J. Cell Biol. 163 (2003) 1351-1362
4. Cheng H.J., and Flanagan J.G. Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases. Cell 79 (1994) 157-168
5. Cheng Y.F., and Kramer R.H. Human microvascular endothelial cells express integrin-related complexes that mediate adhesion to the extracellular matrix. J. Cell. Physiol. 139 (1989) 275-286
6. Civjan N.R., Civjan N.R., Bayburt T.H., Schuler M.A., and Sligar S.G. Direct solubilization of heterologously expressed membrane proteins by incorporation into nanoscale lipid bilayers. Biotechniques 35 (2003) 556-560 562-563
7. Coon J.J., Syka J.E.P., Shabanowitz J., and Hunt D.F. Protein identification using sequential ion/ion reactions and tandem mass spectrometry. Proc. Natl. Acad. Sci. USA 102 (2005) 9463-9468
8. DeFreitas M.F., Yoshida C.K., Frazier W.A., Mendrick D.L., Kypta R.M., and Reichardt L.F. Identification of integrin alpha 3 beta 1 as a neuronal thrombospondin receptor mediating neurite outgrowth. Neuron 15 (1995) 333-343
9. Denda S., Müller U., Crossin K.L., Erickson H.P., and Reichardt L.F. Utilization of a soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: Murine alpha 8 beta 1 binds to the RGD site in tenascin-C fragments, but not to native tenascin-C. Biochemistry 37 (1998) 5464-5474
10. Denda S., Reichardt L.F., and Müller U. Identification of osteopontin as a novel ligand for the integrin alpha8 beta1 and potential roles for this integrin-ligand interaction in kidney morphogenesis. Mol. Biol. Cell 9 (1998) 1425-1435
11. Derynck R., and Zhang Y.E. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425 (2003) 577-584
12. Flanagan J.G., and Leder P. The kit ligand: A cell surface molecule altered in steel mutant fibroblasts. Cell 63 (1990) 185-194
13. Geiger B., Bershadsky A., Pankov R., and Yamada K.M. Transmembrane crosstalk between the extracellular matrix-cytoskeleton crosstalk. Nat. Rev. Mol. Cell Biol. 2 (2001) 793-805
14. Giancotti F.G., and Tarone G. Positional control of cell fate through joint integrin/receptor protein kinase signaling. Annu. Rev. Cell Dev. Biol. 19 (2003) 173-206
15. Han J., Lim C.J., Watanabe N., Soriani A., Ratnikov B., Calderwood D.A., Puzon-McLaughlin W., Lafuente E.M., Boussiotis V.A., Shattil S.J., and Ginsberg M.H. Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3. Curr. Biol. 16 (2006) 1796-1806
16. Harlow E., and Lane D. "Antibodies: A Laboratory Manual." (1988), Cold Spring Harbor Press, Cold Spring Harbor, NY
17. Hemler M.E., Huang C., Takada Y., Schwarz L., Strominger J.L., and Clabby M.L. Characterization of the cell surface heterodimer VLA-4 and related peptides. J. Biol. Chem. 262 (1987) 11478-11485
18. Higgins J.M., Mandlebrot D.A., Shaw S.K., Russell G.J., Murphy E.A., Chen Y.T., Nelson W.J., Parker C.M., and Brenner M.B. Direct and regulated interaction of integrin alphaEbeta7 with E-cadherin. J. Cell Biol. 140 (1998) 197-210
19. Hildebrand J.D., Schaller M.D., and Parsons J.T. Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase. Mol. Biol. Cell 6 (1995) 637-647
20. Horwitz A., Duggan K., Buck C., Beckerle M.C., and Burridge K. Interaction of plasma membrane fibronectin receptor with talin-a transmembrane linkage. Nature 320 (1986) 531-533
21. Howe A., Aplin A.E., Alahari S., and Juliano R.L. Integrin signaling and cell growth control. Curr. Opin. Cell Biol. 10 (1998) 220-231
22. Huang J., Bridges L.C., and White J.M. Selective modulation of integrin-mediated cell migration by distinct ADAM family members. Mol. Biol. Cell 16 (2005) 4982-4991
23. Hynes R.O. Integrins: Bidirectional, allosteric signaling machines. Cell 110 (2002) 673-687
24. Jones K.R., Fariñas I., Backus C., and Reichardt L.F. Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76 (1994) 989-999
25. Kim M., Carman C.V., and Springer T.A. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science 301 (2003) 1720-1725
26. Koivunen E., Wang B., and Ruoslahti E. Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library. J. Cell Biol. 124 (1994) 373-380
27. Koivunen E., Wang B., and Ruoslahti E. Phage libraries displaying cyclic peptides with different ring sizes: Ligand specificities of the RGD-directed integrins. Bio./Technol. 13 (1995) 265-270
28. Kugler M.C., Wei Y., and Chapman H.A. Urokinase receptor and integrin interactions. Curr. Pharm. Des. 9 (2003) 1565-1574
29. Labadia M.E., Jeanfavre D.D., Caviness G.O., and Morelock M.M. Molecular regulation of the interaction between leukocyte function-associated antigen-1 and soluble ICAM-1 by divalent metal cations. J. Immunol. 161 (1998) 836-842
30. Lagenaur C., and Lemmon V. An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension. Proc. Natl. Acad. Sci. USA 84 (1987) 7753-7757
31. Lammerding J., Kazarov A.R., Huang H., Lee R.T., and Hemler M.E. Tetraspanin CD151 regulates alpha6beta1 integrin adhesion strengthening. Proc. Natl. Acad. Sci. USA 100 (2003) 7616-7621
32. Lander, et al. Initial sequencing and analysis of the human genome. Nature 409 (2001) 860-921
33. Leitz A.J., Bayburt T.H., Barnakov A.N., Springer B.A., and Sligar S.G. Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology. Biotechniques 40 (2006) 601-602 604, 606, passim
34. Luo B.H., Takagi J., and Springer T.A. Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides. J. Biol. Chem. 279 (2004) 10215-10221
35. Massague J. Identification of receptors for type-beta transforming growth factor. Methods Enzymol. 146 (1987) 174-195
36. Miyake K., Weissman I.L., Greenberger J.S., and Kincade P.W. Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis. J. Exp. Med. 173 (1991) 599-607
37. Muller U., Wang D., Denda S., Meneses J.J., Pedersen R.A., and Reichardt L.F. Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis. Cell 88 (1997) 603-613
38. Munger J.S., Harpel J.G., Giancotti F.G., and Rifkin D.B. Interactions between growth factors and integrins: Latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1. Mol. Biol. Cell 9 (1998) 2627-2638
39. Munger J.S., Harpel J.G., Giancotti F.G., and Rifkin D.B. The integrin alpha v beta 6 binds and activates latent TGF beta 1: A mechanism for regulating pulmonary inflammation and fibrosis. Cell 96 (1999) 319-328
40. Pfaff M., Göhring W., Brown J.C., and Timpl R. Binding of purified collagen receptors (alpha 1 beta 1, alpha 2 beta 1) and RGD-dependent integrins to laminins and laminin fragments. Eur. J. Biochem. 225 (1994) 975-984
41. Sacca B., and Moroder L. Synthesis of heterotrimeric collagen peptides containing the alpha1beta1 integrin recognition site of collagen type IV. J. Peptide Sci. 8 (2002) 192-204
42. Shimaoka M., Ferzly M., Oxvig C., Takagi J., and Springer T.A. Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo. Proc. Natl. Acad. Sci. USA 98 (2001) 6009-6014
43. Tadokoro S., Shattil S.J., Eto K., Tai V., Liddington R.C., de Pereda J.M., Ginsberg M.H., and Calderwood D.A. Talin binding to integrin beta tails: A final common step in integrin activation. Science 302 (2003) 103-106
44. Takagi J., Petre B.M., Walz T., and Springer T.A. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell 110 (2002) 599-611
45. Tomaselli K.J., Damsky C.H., and Reichardt L.F. Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: Identification of integrin-related glycoproteins involved in attachment and process outgrowth. J. Cell Biol. 105 (1987) 2347-2358
46. Varnum-Finney B., Venstrom K., Muller U., Kypta R., Backus C., Chiquet M., and Reichardt L.F. The integrin receptor alpha 8 beta 1 mediates interactions of embryonic chick motor and sensory neurons with tenascin-C. Neuron 14 (1995) 1213-1222
47. Wei Y., Czekay R.P., Robillard L., Kugler M.C., Zhang F., Kim K.K., Xiong J.P., Humphries M.J., and Chapman H.A. Regulation of alpha5beta1 integrin conformation and function by urokinase receptor binding. J. Cell Biol. 168 (2005) 501-511
48. White J.M. ADAMs: Modulators of cell-cell and cell-matrix interactions. Curr. Opin. Cell Biol. 15 (2003) 598-606