Towards an understanding of the transcription factor network of dendritic cell development

Trends in Immunology

Volumn 27, Issue 3, 2006, Pages 140-145

  Zenke, Martin ^a,b   Hieronymus, Thomas ^a,b  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IKAROS TRANSCRIPTION FACTOR; INHIBITOR OF DIFFERENTIATION 2; INTERFERON REGULATORY FACTOR 2; INTERFERON REGULATORY FACTOR 4; INTERFERON REGULATORY FACTOR 8; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GFI1; TRANSCRIPTION FACTOR PU 1; TRANSCRIPTION FACTOR RELB; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG;

CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL POPULATION; DENDRITIC CELL; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNE SYSTEM; LANGERHANS CELL; LYMPHOID CELL; NONHUMAN; REVIEW;

ANIMALS; DENDRITIC CELLS; HEMATOPOIESIS; HUMANS; MICE; TRANSCRIPTION FACTORS;

EID: 33644518698     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2005.12.007     Document Type: Review

References (63)

1. J. Banchereau, and R.M. Steinman Dendritic cells and the control of immunity Nature 392 1998 245 252
2. J. Banchereau Immunobiology of dendritic cells Annu. Rev. Immunol. 18 2000 767 811
3. K. Shortman, and Y.J. Liu Mouse and human dendritic cell subtypes Nat. Rev. Immunol. 2 2002 151 161
4. C. Ardavin Origin, precursors and differentiation of mouse dendritic cells Nat. Rev. Immunol. 3 2003 582 590
5. A. D'Amico, and L. Wu The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3 J. Exp. Med. 198 2003 293 303
6. H. Karsunky Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo J. Exp. Med. 198 2003 305 313
7. H. Karsunky Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursors Exp. Hematol. 33 2005 173 181
8. G. Orphanides, and D. Reinberg A unified theory of gene expression Cell 108 2002 439 451
9. I.L. Weissman Stem cells: units of development, units of regeneration, and units in evolution Cell 100 2000 157 168
10. S.H. Orkin Diversification of haematopoietic stem cells to specific lineages Nat. Rev. Genet. 1 2000 57 64
11. T. Graf Differentiation plasticity of hematopoietic cells Blood 99 2002 3089 3101
12. J. Adolfsson Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential: a revised road map for adult blood lineage commitment Cell 121 2005 295 306
13. K. Georgopoulos The Ikaros gene is required for the development of all lymphoid lineages Cell 79 1994 143 156
14. L. Wu Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage Immunity 7 1997 483 492
15. A. Nichogiannopoulou Defects in hemopoietic stem cell activity in Ikaros mutant mice J. Exp. Med. 190 1999 1201 1214
16. Y. Laouar STAT3 is required for Flt3L-dependent dendritic cell differentiation Immunity 19 2003 903 912
17. S.L. Nutt Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors J. Exp. Med. 201 2005 221 231
18. A. Guerriero PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells Blood 95 2000 879 885
19. K.L. Anderson Transcription factor PU.1 is necessary for development of thymic and myeloid progenitor-derived dendritic cells J. Immunol. 164 2000 1855 1861
20. Y. Bakri Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fate Blood 105 2005 2707 2716
21. E. Maraskovsky Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified J. Exp. Med. 184 1996 1953 1962
22. H.J. McKenna Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells Blood 95 2000 3489 3497
23. H.J. McKenna Role of hematopoietic growth factors/flt3 ligand in expansion and regulation of dendritic cells Curr. Opin. Hematol. 8 2001 149 154
24. K. Brasel Generation of murine dendritic cells from flt3-ligand- supplemented bone marrow cultures Blood 96 2000 3029 3039
25. P. Brawand Murine plasmacytoid pre-dendritic cells generated from Flt3 ligand-supplemented bone marrow cultures are immature APCs J. Immunol. 169 2002 6711 6719
26. M. Gilliet The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor J. Exp. Med. 195 2002 953 958
27. G. Boehmelt Dendritic cell progenitor is transformed by a conditional v-Rel estrogen receptor fusion protein v-RelER Cell 80 1995 341 352
28. L. Burkly Expression of relB is required for the development of thymic medulla and dendritic cells Nature 373 1995 531 536
29. F. Weih Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family Cell 80 1995 331 340
30. L. Wu RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells Immunity 9 1998 839 847
31. T. Kobayashi TRAF6 is a critical factor for dendritic cell maturation and development Immunity 19 2003 353 363
32. B. Platzer RelB regulates human dendritic cell subset development by promoting monocyte intermediates Blood 104 2004 3655 3663
33. F. Ouaaz Dendritic cell development and survival require distinct NF-kappaB subunits Immunity 16 2002 257 270
34. G. Franzoso Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture J. Exp. Med. 187 1998 147 159
35. K. Speirs Cutting edge: NF-kappa B2 is a negative regulator of dendritic cell function J. Immunol. 172 2004 752 756
36. Y.J. Liu IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors Annu. Rev. Immunol. 23 2005 275 306
37. C. Asselin-Paturel Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology Nat. Immunol. 2 2001 1144 1150
38. H. Nakano CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells J. Exp. Med. 194 2001 1171 1178
39. M. O'Keefe Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8+ dendritic cells only after microbial stimulus J. Exp. Med. 196 2002 1307 1319
40. T. Tamura IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity J. Immunol. 174 2005 2573 2581
41. G. Schiavoni ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells J. Exp. Med. 196 2002 1415 1425
42. H. Tsujimura Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells J. Immunol. 170 2003 1131 1135
43. S. Suzuki Critical roles of interferon regulatory factor 4 in CD11bhighCD8alpha- dendritic cell development Proc. Natl. Acad. Sci. U. S. A. 101 2004 8981 8986
44. G. Schiavoni ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells Blood 103 2004 2221 2228
45. J. Aliberti Essential role for ICSBP in the in vivo development of murine CD8alpha+ dendritic cells Blood 101 2003 305 310
46. E. Ichikawa Defective development of splenic and epidermal CD4+ dendritic cells in mice deficient for IFN regulatory factor-2 Proc. Natl. Acad. Sci. U. S. A. 101 2004 3909 3914
47. R. Schotte The transcription factor Spi-B is expressed in plasmacytoid DC precursors and inhibits T-, B-, and NK-cell development Blood 101 2003 1015 1023
48. R. Schotte The ETS transcription factor Spi-B is required for human plasmacytoid dendritic cell development J. Exp. Med. 200 2004 1503 1509
49. H. Spits Id2 and Id3 inhibit development of CD34(+) stem cells into predendritic cell (pre-DC)2 but not into pre-DC1. Evidence for a lymphoid origin of pre-DC2 J. Exp. Med. 192 2000 1775 1784
50. C. Hacker Transcriptional profiling identifies Id2 function in dendritic cell development Nat. Immunol. 4 2003 380 386
51. T. Kusunoki TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice J. Allergy Clin. Immunol. 111 2003 136 142
52. B.Z. Levi ICSBP/IRF-8 transactivation: a tale of protein-protein interaction J. Interferon Cytokine Res. 22 2002 153 160
53. M. Merad Langerhans cells renew in the skin throughout life under steady-state conditions Nat. Immunol. 3 2002 1135 1141
54. C. Caux CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha J. Exp. Med. 184 1996 695 706
55. S. Jaksits CD34+ cell-derived CD14+ precursor cells develop into Langerhans cells in a TGF-beta 1-dependent manner J. Immunol. 163 1999 4869 4877
56. X.S. Ju Towards determining the differentiation program of antigen-presenting dendritic cells by transcriptional profiling Eur. J. Cell Biol. 82 2003 75 86
57. X.S. Ju, and M. Zenke Differentiation of human antigen-presenting dendritic cells from CD34+ hematopoietic stem cells in vitro Methods Mol. Biol. 215 2003 399 407
58. H. Strobl TGF-beta 1 promotes in vitro development of dendritic cells from CD34+ hemopoietic progenitors J. Immunol. 157 1996 1499 1507
59. H. Strobl, and W. Knapp TGF-beta1 regulation of dendritic cells Microbes Infect. 1 1999 1283 1290
60. T.A. Borkowski A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells J. Exp. Med. 184 1996 2417 2422
61. N.O. Fortunel Transforming growth factor-beta: pleiotropic role in the regulation of hematopoiesis Blood 96 2000 2022 2036
62. O. Fainaru Runx3 regulates mouse TGF-beta-mediated dendritic cell function and its absence results in airway inflammation EMBO J. 23 2004 969 979
63. C. Rathinam The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function Immunity 22 2005 717 728