Biomimetic interactions of proteins with functionalized nanoparticles: A thermodynamic study

Journal of the American Chemical Society

Volumn 129, Issue 35, 2007, Pages 10747-10753

  De, Mrinmoy ^a   You, Chang Cheng ^a   Srivastava, Sudhanshu ^a   Rotello, Vincent M ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMIMETICS; ENTROPY; LIGANDS; MONOLAYERS; NANOPARTICLES; THERMODYNAMICS;

BINDING THERMODYNAMICS; ENTHALPY-ENTROPY COMPENSATION; HOST-GUEST SYSTEMS; PROTEIN SURFACES;

PROTEINS;

AMINO ACID; CHYMOTRYPSIN A; CYTOCHROME C; GOLD; HISTONE; NANOPARTICLE; PROTEIN DERIVATIVE; BIOMIMETIC MATERIAL; CHYMOTRYPSIN; METAL NANOPARTICLE; UNCLASSIFIED DRUG;

ARTICLE; CORRELATION ANALYSIS; ENTHALPY; ENTROPY; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; PROTEIN ANALYSIS; THERMODYNAMICS; CALORIMETRY; CHEMICAL STRUCTURE; CHEMISTRY; KINETICS; PROTEIN BINDING;

AMINO ACIDS; BIOMIMETIC MATERIALS; CALORIMETRY; CHYMOTRYPSIN; CYTOCHROMES C; GOLD; HISTONES; HYDROPHOBICITY; KINETICS; METAL NANOPARTICLES; MODELS, MOLECULAR; PROTEIN BINDING; THERMODYNAMICS;

EID: 34848898194     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja071642q     Document Type: Article

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104. TEM measurements on NP_Ala revealed an average particle size of 2.1 ± 0.4 nm (Figure S1). TGA revealed that the weight percentage of organic ligands in the NPs is 36% (Figure S2). Accordingly, the average molecular weight of the NP is estimated as 100 kDa, which was used for the preparation of NP solutions.