A biosensor that uses ion-channel switches

Nature

Volumn 387, Issue 6633, 1997, Pages 580-583

  Cornell, B A ^a   Braach Maksvytis, V L B ^a   King, L G ^a   Osman, P D J ^a   Raguse, B ^a   Wieczorek, L ^a   Pace, R J ^a,b  

^a Co oper Res Ctr Molec Eng T ^*  (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BIOLOGICAL MEMBRANES; ELECTRIC CONDUCTIVITY; ELECTRODES; IONS; PROTEINS; SWITCHES;

ION CHANNEL SWITCHES;

BIOSENSORS;

ION CHANNEL;

ANALYTIC METHOD; ARTICLE; BIOSENSOR; CELL TYPE; GLUCOSE BLOOD LEVEL; LIPID MEMBRANE; PRIORITY JOURNAL;

BIOSENSING TECHNIQUES; DIGOXIN; ELECTRIC CONDUCTIVITY; GRAMICIDIN; IMMUNOGLOBULIN FRAGMENTS; ION CHANNELS; LIPID BILAYERS; SENSITIVITY AND SPECIFICITY; THYROTROPIN;

EID: 0031554429     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/42432     Document Type: Article

References (18)

1. Scheller, F. W., Schubert, F. & Fedrowitz, J. (eds) Frontiers in Biosensorics Vols I & II (Birkhauser, Berlin, 1996).
2. Avrone, E. & Rospars, J. P. Modelling insect olfactory neurone signaling by a network utilising disinhibition. Biosystems 36, 101-108 (1995).
3. Reiken, S. R. et al. Bispecific antibody modification of nicotine acetycholine receptors for biosensing. Biosens. Bioelectron. 11, 91-102 (1996).
4. Koeppe, R. E. & Andersen, O. S. Engineering the gramicidin channel. Annu. Rev. Biophys. Biomol. Struct. 25, 231-258 (1996).
5. McConnell, H. M., Watts, T. H., Weis, R. M. & Brian, A. A. Supported planar membranes in studies of cell-cell recognition in the immune system. Biochim. Biophys. Acta 864, 95-106 (1986).
6. Florin, E.-L. & Gaub, H. E. Painted supported lipid membranes. Biophys. J. 64, 375-383 (1993).
7. Lang, H., Duschl, C. & Vogel, H. A new class of thiolipids for the attachment of lipid bilayers on gold surfaces. Langmuir 10, 197-210 (1994).
8. Steizle, M., Weismuller, G. & Sackmann, E. On the application of supported bilayers as receptive layers for biosensors with electrical detection. J. Phys. Chem. 97, 2974-2981 (1993).
9. Plant, A. L., Gueguetchkeri, M. & Yap, W. Supported phospholipid/alkanethiol biomimetic membranes: insulating properties. Biophys. J. 67, 1126-1133 (1994).
10. Folkers, J. P., Laibinis, P. E., Whitesides, G. M. & Deutch, J. Phase behaviour of two-component self-assembled monolayers of alkanethiolates on gold. J. Phys. Chem. 98, 563-571 (1994).
11. Steinem, C., Janschoff, A., Ulrich, W. P., Sieber, M. & Galla, H. J. Impedance analysis of supported lipid bilayer membranes: a scrutiny of different preparation techniques. Biochem. Biophys. Acta 1279, 169-180 (1996).
12. Lu, X. D., Ottova, A. L. & Tien, H. T. Biophysical aspects of agar-gel supported bilayer lipid membranes: a new method for forming and studying planar bilayer lipid membranes. Bioelectrochem. Bioenerget. 39, 285-289 (1996).
13. Heysel, S., Vogel, H., Sanger, M. & Sigrist, H. Covalent attachment of functionalised lipid bilayers to planar waveguides for measuring protein binding to biomimetic membranes. Protein Sci. 4, 2532-2544 (1995).
14. Rickert, J., Weiss, T., Kraas, W., Jung, G. & Gopel, W. A new affinity biosensor: self-assembled thiols as selective monolayer coatings of quartz crystal microbalances. Biosens. Bioelectron. 11, 591-598 (1996).
15. Sackmann, E. Supported membranes: scientific and practical applications. Science 271, 43-48 (1996).
16. Stetter, K. O. Hypothermophilic procaryotes. FEMS Microbiol. Rev. 18, 149-158 (1996).
17. Hladky, S. B., Leung, J. C. H. & Fitzgerald, W. The mechanism of ion conduction by valinomycin-analysis of charge pulse responses. Biophys. J. 69, 1758-1772 (1995).
18. Nikolelis, D., Siontorou, C. G., Krull, U. J. & Katrivanos, P. L. Ammonium ion minisensors from self-assembled bilayer lipid membranes using gramicidin as an ionophore. Modulation of ammonium selectivity by Platelet Activating Factor. Anal. Chem. 68, 1735-1741 (1996).