Conformational changes during normal and error-prone incorporation of nucleotides by a Y-family DNA polymerase detected by 2-aminopurine fluorescence

Biochemistry

Volumn 46, Issue 38, 2007, Pages 10790-10803

  DeLucia, Angela M ^a   Grindley, Nigel D F ^a   Joyce, Catherine M ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BYPASS POLYMERASES; DELETION ERRORS; DNA POLYMERASES; PRIMER TERMINUS;

BINDING ENERGY; CONFORMATIONS; CRYSTAL STRUCTURE; DNA; FLUORESCENCE; NUCLEOTIDES;

ENZYME ACTIVITY;

2 AMINOPURINE; DNA POLYMERASE; DNA POLYMERASE Y; KLENOW FRAGMENT; NUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DNA DAMAGE; DNA SYNTHESIS; ENZYME SUBSTRATE; FLUORESCENCE; PRIORITY JOURNAL; REACTION ANALYSIS;

2-AMINOPURINE; ARCHAEAL PROTEINS; BASE PAIR MISMATCH; BASE SEQUENCE; DEOXYRIBONUCLEOTIDES; DNA POLYMERASE BETA; DNA POLYMERASE I; DNA REPAIR; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; FLUORESCENT DYES; FRAMESHIFT MUTATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; NUCLEIC ACID CONFORMATION; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY; SULFOLOBUS; TEMPLATES, GENETIC;

EID: 34748886033     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi7006756     Document Type: Article

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