The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases

Journal of Biological Chemistry

Volumn 281, Issue 37, 2006, Pages 27286-27291

  DeLucia, Angela M ^a   Chaudhuri, Santanov ^a   Potapova, Olga ^a   Grindley, Nigel D F ^a   Joyce, Catherine M ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CONFORMATIONS; DNA; ENZYMES; SUBSTRATES;

DNA POLYMERASES; NUCLEOTIDE; PURINE-PYRIMIDINE MISPAIRS; STERIC GATE MUTANTS;

MUTAGENESIS;

DNA POLYMERASE; NUCLEOTIDE; PARATHION; PHENYLALANINE; PURINE; PYRIMIDINE; RIBONUCLEOTIDE;

ARTICLE; BINDING SITE; CONFORMATION; DNA TEMPLATE; GEOMETRY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSOR;

BASE PAIR MISMATCH; BASE SEQUENCE; BINDING SITES; DEOXYRIBONUCLEOTIDES; DNA; DNA-DIRECTED DNA POLYMERASE; GLUTAMIC ACID; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PURINES; PYRIMIDINES; RIBONUCLEOTIDES;

EID: 33748742873     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604393200     Document Type: Article

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