-
1
-
-
0842327494
-
Mechanisms of hepatitis C virus infection
-
Moriishi K, Matsuura Y. Mechanisms of hepatitis C virus infection. Antivir Chem Chemother 2003; 14: 285-297.
-
(2003)
Antivir Chem Chemother
, vol.14
, pp. 285-297
-
-
Moriishi, K.1
Matsuura, Y.2
-
2
-
-
0033916804
-
Epidemiology of hepatitis C: Geographic differences and temporal trends
-
Wasley A, Alter MJ. Epidemiology of hepatitis C: geographic differences and temporal trends. Semin Liver Dis 2000; 20: 1-16.
-
(2000)
Semin Liver Dis
, vol.20
, pp. 1-16
-
-
Wasley, A.1
Alter, M.J.2
-
3
-
-
1842479859
-
Diagnosis, management, and treatment of hepatitis C
-
Strader DB, Wright T, Thomas DL, Seeff LB. Diagnosis, management, and treatment of hepatitis C. Hepatology 2004; 39: 1147-1171.
-
(2004)
Hepatology
, vol.39
, pp. 1147-1171
-
-
Strader, D.B.1
Wright, T.2
Thomas, D.L.3
Seeff, L.B.4
-
4
-
-
0035934568
-
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
-
Manns MP, McHutchison JG, Gordon SC, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358: 958-965.
-
(2001)
Lancet
, vol.358
, pp. 958-965
-
-
Manns, M.P.1
McHutchison, J.G.2
Gordon, S.C.3
-
5
-
-
0345188811
-
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
-
Lohmann V, Korner F, Koch J, Herian U, Theilmann L, Bartenschlager R. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 1999; 285: 110-113.
-
(1999)
Science
, vol.285
, pp. 110-113
-
-
Lohmann, V.1
Korner, F.2
Koch, J.3
Herian, U.4
Theilmann, L.5
Bartenschlager, R.6
-
6
-
-
33644839220
-
Host sphingolipid biosynthesis as a target for hepatitis C virus therapy
-
Sakamoto H, Okamoto K, Aoki M, et al. Host sphingolipid biosynthesis as a target for hepatitis C virus therapy. Nat Chem Biol 2005; 1: 333-337.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 333-337
-
-
Sakamoto, H.1
Okamoto, K.2
Aoki, M.3
-
7
-
-
4644221540
-
Progress and development of small molecule HCV antivirals
-
Ni ZJ, Wagman AS. Progress and development of small molecule HCV antivirals. Curr Opin Drug Discov Devel 2004; 7: 446-459.
-
(2004)
Curr Opin Drug Discov Devel
, vol.7
, pp. 446-459
-
-
Ni, Z.J.1
Wagman, A.S.2
-
8
-
-
2342420348
-
In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: Structural analysis indicates different resistance mechanisms
-
Lin C, Lin K, Luong YP, et al. In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms. J Biol Chem 2004; 279: 17508-17514.
-
(2004)
J Biol Chem
, vol.279
, pp. 17508-17514
-
-
Lin, C.1
Lin, K.2
Luong, Y.P.3
-
9
-
-
21244433445
-
Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase
-
Watashi K, Ishii N, Hijikata M, et al. Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase. Mol Cell 2005; 19: 111-122.
-
(2005)
Mol Cell
, vol.19
, pp. 111-122
-
-
Watashi, K.1
Ishii, N.2
Hijikata, M.3
-
10
-
-
33750219537
-
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90
-
Okamoto T, Nishimura Y, Ichimura T, et al. Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90. EMBO J 2006; 25: 5015-5025.
-
(2006)
EMBO J
, vol.25
, pp. 5015-5025
-
-
Okamoto, T.1
Nishimura, Y.2
Ichimura, T.3
-
11
-
-
1542378867
-
Peginterferon- alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
-
Hadziyannis SJ, Sette H Jr, Morgan TR, et al. Peginterferon- alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004; 140: 346-355.
-
(2004)
Ann Intern Med
, vol.140
, pp. 346-355
-
-
Hadziyannis, S.J.1
Sette Jr, H.2
Morgan, T.R.3
-
12
-
-
0037179698
-
Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
-
Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002; 347: 975-982.
-
(2002)
N Engl J Med
, vol.347
, pp. 975-982
-
-
Fried, M.W.1
Shiffman, M.L.2
Reddy, K.R.3
-
14
-
-
22544470874
-
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
-
Wakita T, Pietschmann T, Kato T, et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 2005; 11: 791-796.
-
(2005)
Nat Med
, vol.11
, pp. 791-796
-
-
Wakita, T.1
Pietschmann, T.2
Kato, T.3
-
15
-
-
23044437222
-
Complete replication of hepatitis C virus in cell culture
-
Lindenbach BD, Evans MJ, Syder AJ, et al. Complete replication of hepatitis C virus in cell culture. Science 2005; 309: 623-626.
-
(2005)
Science
, vol.309
, pp. 623-626
-
-
Lindenbach, B.D.1
Evans, M.J.2
Syder, A.J.3
-
16
-
-
0027176287
-
NS3 is a serine protease required for processing of hepatitis C virus polyprotein
-
Tomei L, Failla C, Santolini E, De Francesco R, La Monica N. NS3 is a serine protease required for processing of hepatitis C virus polyprotein. J Virol 1993; 67: 4017-1026.
-
(1993)
J Virol
, vol.67
, pp. 4017-1026
-
-
Tomei, L.1
Failla, C.2
Santolini, E.3
De Francesco, R.4
La Monica, N.5
-
17
-
-
0027414062
-
Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites
-
Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J Virol 1993; 67: 2832-2843.
-
(1993)
J Virol
, vol.67
, pp. 2832-2843
-
-
Grakoui, A.1
McCourt, D.W.2
Wychowski, C.3
Feinstone, S.M.4
Rice, C.M.5
-
18
-
-
17844375654
-
Enzymatic characterization of membrane-associated hepatitis C virus NS3-4A heterocomplex serine protease activity expressed in human cells
-
Hamill P, Jean F. Enzymatic characterization of membrane-associated hepatitis C virus NS3-4A heterocomplex serine protease activity expressed in human cells. Biochemistry 2005; 44: 6586-6596.
-
(2005)
Biochemistry
, vol.44
, pp. 6586-6596
-
-
Hamill, P.1
Jean, F.2
-
19
-
-
0036100578
-
Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex
-
Egger D, Wolk B, Gosert R, et al. Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J Virol 2002; 76: 5974-5984.
-
(2002)
J Virol
, vol.76
, pp. 5974-5984
-
-
Egger, D.1
Wolk, B.2
Gosert, R.3
-
20
-
-
4444377616
-
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
-
Evans MJ, Rice CM, Goff SP. Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication. Proc Natl Acad Sci USA 2004; 101: 13038-13043.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13038-13043
-
-
Evans, M.J.1
Rice, C.M.2
Goff, S.P.3
-
21
-
-
0034623816
-
Efficient initiation of HCV RNA replication in cell culture
-
Blight KJ, Kolykhalov AA, Rice CM. Efficient initiation of HCV RNA replication in cell culture. Science 2000; 290: 1972-1974.
-
(2000)
Science
, vol.290
, pp. 1972-1974
-
-
Blight, K.J.1
Kolykhalov, A.A.2
Rice, C.M.3
-
22
-
-
0030051777
-
Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus
-
Behrens SE, Tomei L, De Francesco R. Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. EMBO J 1996; 15: 12-22.
-
(1996)
EMBO J
, vol.15
, pp. 12-22
-
-
Behrens, S.E.1
Tomei, L.2
De Francesco, R.3
-
23
-
-
27144514348
-
Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B
-
Hamamoto I, Nishimura Y, Okamoto T, et al. Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B. J Virol 2005; 79: 13473-13482.
-
(2005)
J Virol
, vol.79
, pp. 13473-13482
-
-
Hamamoto, I.1
Nishimura, Y.2
Okamoto, T.3
-
24
-
-
0033543959
-
Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein
-
Tu H, Gao L, Shi ST, et al. Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein. Virology 1999; 263: 30-41.
-
(1999)
Virology
, vol.263
, pp. 30-41
-
-
Tu, H.1
Gao, L.2
Shi, S.T.3
-
25
-
-
0024959449
-
Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins
-
Fischer G, Wittmann-Liebold B, Lang K, Kiefhaber T, Schmid FX. Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins. Nature 1989; 337: 476-478.
-
(1989)
Nature
, vol.337
, pp. 476-478
-
-
Fischer, G.1
Wittmann-Liebold, B.2
Lang, K.3
Kiefhaber, T.4
Schmid, F.X.5
-
26
-
-
0024442393
-
A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin
-
Siekierka JJ, Hung SH, Poe M, Lin CS, Sigal NH. A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin. Nature 1989; 341: 755-757.
-
(1989)
Nature
, vol.341
, pp. 755-757
-
-
Siekierka, J.J.1
Hung, S.H.2
Poe, M.3
Lin, C.S.4
Sigal, N.H.5
-
27
-
-
0024450049
-
FK-506, a potent novel immunosuppressive agent, binds to a cytosolic protein which is distinct from the cyclosporin A-binding protein, cyclophilin
-
Siekierka JJ, Staruch MJ, Hung SH, Sigal NH. FK-506, a potent novel immunosuppressive agent, binds to a cytosolic protein which is distinct from the cyclosporin A-binding protein, cyclophilin. J Immunol 1989; 143: 1580-1583.
-
(1989)
J Immunol
, vol.143
, pp. 1580-1583
-
-
Siekierka, J.J.1
Staruch, M.J.2
Hung, S.H.3
Sigal, N.H.4
-
28
-
-
0028349613
-
A novel peptidyl-prolyl cis/trans isomerase from Escherichia coli
-
Rahfeld JU, Schierhorn A, Mann K, Fischer G. A novel peptidyl-prolyl cis/trans isomerase from Escherichia coli. FEBS Lett 1994; 343: 65-69.
-
(1994)
FEBS Lett
, vol.343
, pp. 65-69
-
-
Rahfeld, J.U.1
Schierhorn, A.2
Mann, K.3
Fischer, G.4
-
30
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
Liu J, Farmer JD Jr, Lane WS, Friedman J, Weissman I, Schreiber SL. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 1991; 66: 807-815.
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Farmer Jr, J.D.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
31
-
-
0027207885
-
Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B
-
Luban J, Bossolt KL, Franke EK, Kalpana GV, Goff SP. Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B. Cell 1993; 73: 1067-1078.
-
(1993)
Cell
, vol.73
, pp. 1067-1078
-
-
Luban, J.1
Bossolt, K.L.2
Franke, E.K.3
Kalpana, G.V.4
Goff, S.P.5
-
32
-
-
0033602561
-
Cyclophilin A incorporation is not required for human immunodeficiency virus type 1 particle maturation and does not destabilize the mature capsid
-
Wiegers K, Rutter G, Schubert U, Grattinger M, Krausslich HG. Cyclophilin A incorporation is not required for human immunodeficiency virus type 1 particle maturation and does not destabilize the mature capsid. Virology 1999; 257: 261-274.
-
(1999)
Virology
, vol.257
, pp. 261-274
-
-
Wiegers, K.1
Rutter, G.2
Schubert, U.3
Grattinger, M.4
Krausslich, H.G.5
-
33
-
-
1542288934
-
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys
-
Stremlau M, Owens CM, Perron MJ, Kiessling M, Autissier P, Sodroski J. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 2004; 427: 848-853.
-
(2004)
Nature
, vol.427
, pp. 848-853
-
-
Stremlau, M.1
Owens, C.M.2
Perron, M.J.3
Kiessling, M.4
Autissier, P.5
Sodroski, J.6
-
34
-
-
3242876747
-
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1
-
Sayah DM, Sokolskaja E, Berthoux L, Luban J. Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1. Nature 2004; 430: 569-573.
-
(2004)
Nature
, vol.430
, pp. 569-573
-
-
Sayah, D.M.1
Sokolskaja, E.2
Berthoux, L.3
Luban, J.4
-
35
-
-
0025735861
-
S-cyclophilin. New member of the cyclophilin family associated with the secretory pathway
-
Caroni P, Rothenfluh A, McGlynn E, Schneider C. S-cyclophilin. New member of the cyclophilin family associated with the secretory pathway. J Biol Chem 1991; 266: 10739-10742.
-
(1991)
J Biol Chem
, vol.266
, pp. 10739-10742
-
-
Caroni, P.1
Rothenfluh, A.2
McGlynn, E.3
Schneider, C.4
-
36
-
-
0025764555
-
A novel secreted cyclophilin-like protein (SCYLP)
-
Spik G, Haendler B, Delmas O, et al. A novel secreted cyclophilin-like protein (SCYLP). J Biol Chem 1991; 266: 10735-10738.
-
(1991)
J Biol Chem
, vol.266
, pp. 10735-10738
-
-
Spik, G.1
Haendler, B.2
Delmas, O.3
-
37
-
-
0028361571
-
Characterization of surface binding sites for cyclophilin B on a human tumor T-cell line
-
Allain F, Denys A, Spik G. Characterization of surface binding sites for cyclophilin B on a human tumor T-cell line. J Biol Chem 1994; 269: 16537-16540.
-
(1994)
J Biol Chem
, vol.269
, pp. 16537-16540
-
-
Allain, F.1
Denys, A.2
Spik, G.3
-
38
-
-
0034463072
-
Role of cyclophilin B in prolactin signal transduction and nuclear retrotranslocation
-
Rycyzyn MA, Reilly SC, O'Malley K, Clevenger CV. Role of cyclophilin B in prolactin signal transduction and nuclear retrotranslocation. Mol Endocrinol 2000; 14: 1175-1186.
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1175-1186
-
-
Rycyzyn, M.A.1
Reilly, S.C.2
O'Malley, K.3
Clevenger, C.V.4
-
39
-
-
0037415754
-
Scrapie-like prion protein accumulates in aggresomes of cyclosporin A-treated cells
-
Cohen E, Taraboulos A. Scrapie-like prion protein accumulates in aggresomes of cyclosporin A-treated cells. EMBO J 2003; 22: 404-417.
-
(2003)
EMBO J
, vol.22
, pp. 404-417
-
-
Cohen, E.1
Taraboulos, A.2
-
40
-
-
33646194456
-
Diverse effects of cyclosporine on hepatitis C virus strain replication
-
Ishii N, Watashi K, Hishiki T, et al. Diverse effects of cyclosporine on hepatitis C virus strain replication. J Virol 2006; 80: 4510-4520.
-
(2006)
J Virol
, vol.80
, pp. 4510-4520
-
-
Ishii, N.1
Watashi, K.2
Hishiki, T.3
-
41
-
-
0142182744
-
Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes
-
Watashi K, Hijikata M, Hosaka M, Yamaji M, Shimotohno K. Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes. Hepatology 2003; 38: 1282-1288.
-
(2003)
Hepatology
, vol.38
, pp. 1282-1288
-
-
Watashi, K.1
Hijikata, M.2
Hosaka, M.3
Yamaji, M.4
Shimotohno, K.5
-
42
-
-
0038102952
-
Combined interferon alpha2b and cyclosporin A in the treatment of chronic hepatitis C: Controlled trial
-
Inoue K, Sekiyama K, Yamada M, Watanabe T, Yasuda H, Yoshiba M. Combined interferon alpha2b and cyclosporin A in the treatment of chronic hepatitis C: controlled trial. J Gastroenterol 2003; 38: 567-572.
-
(2003)
J Gastroenterol
, vol.38
, pp. 567-572
-
-
Inoue, K.1
Sekiyama, K.2
Yamada, M.3
Watanabe, T.4
Yasuda, H.5
Yoshiba, M.6
-
43
-
-
0029098342
-
Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs
-
Lam E, Martin M, Wiederrecht G. Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs. Gene 1995; 160: 297-302.
-
(1995)
Gene
, vol.160
, pp. 297-302
-
-
Lam, E.1
Martin, M.2
Wiederrecht, G.3
-
44
-
-
23044440890
-
Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin
-
Edlich F, Weiwad M, Erdmann F, et al. Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin. EMBO J 2005; 24: 2688-2699.
-
(2005)
EMBO J
, vol.24
, pp. 2688-2699
-
-
Edlich, F.1
Weiwad, M.2
Erdmann, F.3
-
45
-
-
33744964249
-
The specific FKBP38 inhibitor N-(N′,N′-dimethylcarboxamidomethyl)cycloheximide has potent neuroprotective and neurotrophic properties in brain ischemia
-
Edlich F, Weiwad M, Wildemann D, et al. The specific FKBP38 inhibitor N-(N′,N′-dimethylcarboxamidomethyl)cycloheximide has potent neuroprotective and neurotrophic properties in brain ischemia. J Biol Chem 2006; 281: 14961-14970.
-
(2006)
J Biol Chem
, vol.281
, pp. 14961-14970
-
-
Edlich, F.1
Weiwad, M.2
Wildemann, D.3
-
46
-
-
0345550284
-
Fkbp8: Novel isoforms, genomic organization, and characterization of a forebrain promoter in transgenic mice
-
Nielsen JV, Mitchelmore C, Pedersen KM, Kjaerulff KM, Finsen B, Jensen NA. Fkbp8: novel isoforms, genomic organization, and characterization of a forebrain promoter in transgenic mice. Genomics 2004; 83: 181-192.
-
(2004)
Genomics
, vol.83
, pp. 181-192
-
-
Nielsen, J.V.1
Mitchelmore, C.2
Pedersen, K.M.3
Kjaerulff, K.M.4
Finsen, B.5
Jensen, N.A.6
-
47
-
-
2542555722
-
FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues
-
Bulgakov OV, Eggenschwiler JT, Hong DH, Anderson KV, Li T. FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues. Development 2004; 131: 2149-2159.
-
(2004)
Development
, vol.131
, pp. 2149-2159
-
-
Bulgakov, O.V.1
Eggenschwiler, J.T.2
Hong, D.H.3
Anderson, K.V.4
Li, T.5
-
48
-
-
0027756145
-
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
-
Echelard Y, Epstein DJ, St-Jacques B, et al. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 1993; 75: 1417-1430.
-
(1993)
Cell
, vol.75
, pp. 1417-1430
-
-
Echelard, Y.1
Epstein, D.J.2
St-Jacques, B.3
-
49
-
-
0027939318
-
Products, genetic linkage and limb patterning activity of a murine hedgehog gene
-
Chang DT, Lopez A, von Kessler DP, et al. Products, genetic linkage and limb patterning activity of a murine hedgehog gene. Development 1994; 120: 3339-3353.
-
(1994)
Development
, vol.120
, pp. 3339-3353
-
-
Chang, D.T.1
Lopez, A.2
von Kessler, D.P.3
-
50
-
-
0035252990
-
Specification of neuronal fates in the ventral neural tube
-
Briscoe J, Ericson J. Specification of neuronal fates in the ventral neural tube. Curr Opin Neurobiol 2001; 11: 43-19.
-
(2001)
Curr Opin Neurobiol
, vol.11
, pp. 43-19
-
-
Briscoe, J.1
Ericson, J.2
-
51
-
-
0029777408
-
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
-
Chiang C, Litingtung Y, Lee E, et al. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 1996; 383: 407-413.
-
(1996)
Nature
, vol.383
, pp. 407-413
-
-
Chiang, C.1
Litingtung, Y.2
Lee, E.3
-
52
-
-
0030297553
-
Dual roles for patched in sequestering and transducing Hedgehog
-
Chen Y, Struhl G. Dual roles for patched in sequestering and transducing Hedgehog. Cell 1996; 87: 553-563.
-
(1996)
Cell
, vol.87
, pp. 553-563
-
-
Chen, Y.1
Struhl, G.2
-
53
-
-
0029948270
-
Biochemical evidence that patched is the Hedgehog receptor
-
Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ. Biochemical evidence that patched is the Hedgehog receptor. Nature 1996; 384: 176-179.
-
(1996)
Nature
, vol.384
, pp. 176-179
-
-
Marigo, V.1
Davey, R.A.2
Zuo, Y.3
Cunningham, J.M.4
Tabin, C.J.5
-
54
-
-
0032756914
-
Proteolysis of cubitus interruptus in Drosophila requires phosphorylation by protein kinase A
-
Price MA, Kalderon D. Proteolysis of cubitus interruptus in Drosophila requires phosphorylation by protein kinase A. Development 1999; 126: 4331-4339.
-
(1999)
Development
, vol.126
, pp. 4331-4339
-
-
Price, M.A.1
Kalderon, D.2
-
55
-
-
0032585515
-
Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator
-
Ohlmeyer JT, Kalderon D. Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator. Nature 1998; 396: 749-753.
-
(1998)
Nature
, vol.396
, pp. 749-753
-
-
Ohlmeyer, J.T.1
Kalderon, D.2
-
56
-
-
0037111827
-
A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord
-
Wijgerde M, McMahon JA, Rule M, McMahon AP. A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord. Genes Dev 2002; 16: 2849-2864.
-
(2002)
Genes Dev
, vol.16
, pp. 2849-2864
-
-
Wijgerde, M.1
McMahon, J.A.2
Rule, M.3
McMahon, A.P.4
-
57
-
-
0030866154
-
Altered neural cell fates and medulloblastoma in mouse patched mutants
-
Goodrich LV, Milenkovic L, Higgins KM, Scott MP. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 1997; 277: 1109-1113.
-
(1997)
Science
, vol.277
, pp. 1109-1113
-
-
Goodrich, L.V.1
Milenkovic, L.2
Higgins, K.M.3
Scott, M.P.4
-
58
-
-
0037227946
-
Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis
-
Shirane M, Nakayama KI. Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis. Nat Cell Biol 2003; 5: 28-37.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 28-37
-
-
Shirane, M.1
Nakayama, K.I.2
-
59
-
-
0035923585
-
Host cell factor requirement for hepatitis C virus enzyme maturation
-
Waxman L, Whitney M, Pollok BA, Kuo LC, Darke PL. Host cell factor requirement for hepatitis C virus enzyme maturation. Proc Natl Acad Sci USA 2001; 98: 13931-13935.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13931-13935
-
-
Waxman, L.1
Whitney, M.2
Pollok, B.A.3
Kuo, L.C.4
Darke, P.L.5
-
60
-
-
33846491250
-
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits
-
Naito T, Momose F, Kawaguchi A, Nagata K. Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits. J Virol 2007; 81: 1339-1349.
-
(2007)
J Virol
, vol.81
, pp. 1339-1349
-
-
Naito, T.1
Momose, F.2
Kawaguchi, A.3
Nagata, K.4
-
61
-
-
0346003805
-
Identification of Hsp90 as a stimulatory host factor involved in influenza virus RNA synthesis
-
Momose F, Naito T, Yano K, Sugimoto S, Morikawa Y, Nagata K. Identification of Hsp90 as a stimulatory host factor involved in influenza virus RNA synthesis. J Biol Chem 2002; 277: 45306-45314.
-
(2002)
J Biol Chem
, vol.277
, pp. 45306-45314
-
-
Momose, F.1
Naito, T.2
Yano, K.3
Sugimoto, S.4
Morikawa, Y.5
Nagata, K.6
-
62
-
-
23244444185
-
Herpes simplex virus type 1 DNA polymerase requires the mammalian chaperone hsp90 for proper localization to the nucleus
-
Burch AD, Weller SK. Herpes simplex virus type 1 DNA polymerase requires the mammalian chaperone hsp90 for proper localization to the nucleus. J Virol 2005; 79: 10740-10749.
-
(2005)
J Virol
, vol.79
, pp. 10740-10749
-
-
Burch, A.D.1
Weller, S.K.2
-
63
-
-
18744384675
-
The cellular chaperone heat shock protein 90 facilitates Flock House virus RNA replication in Drosophila cells
-
Kampmueller KM, Miller DJ. The cellular chaperone heat shock protein 90 facilitates Flock House virus RNA replication in Drosophila cells. J Virol 2005; 79: 6827-6837.
-
(2005)
J Virol
, vol.79
, pp. 6827-6837
-
-
Kampmueller, K.M.1
Miller, D.J.2
-
64
-
-
34247191488
-
Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses
-
Connor JH, McKenzie MO, Parks GD, Lyles DS. Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses. Virology 2007; 362: 109-117.
-
(2007)
Virology
, vol.362
, pp. 109-117
-
-
Connor, J.H.1
McKenzie, M.O.2
Parks, G.D.3
Lyles, D.S.4
-
65
-
-
0031018112
-
Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids
-
Hu J, Toft DO, Seeger C. Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids. EMBO J 1997; 16: 59-68.
-
(1997)
EMBO J
, vol.16
, pp. 59-68
-
-
Hu, J.1
Toft, D.O.2
Seeger, C.3
-
66
-
-
0030035038
-
Hsp90 is required for the activity of a hepatitis B virus reverse transcriptase
-
Hu J, Seeger C. Hsp90 is required for the activity of a hepatitis B virus reverse transcriptase. Proc Natl Acad Sci USA 1996; 93: 1060-1064.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1060-1064
-
-
Hu, J.1
Seeger, C.2
-
67
-
-
33846471075
-
Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance
-
Geller R, Vignuzzi M, Andino R, Frydman J. Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance. Genes Dev 2007; 21: 195-205.
-
(2007)
Genes Dev
, vol.21
, pp. 195-205
-
-
Geller, R.1
Vignuzzi, M.2
Andino, R.3
Frydman, J.4
-
68
-
-
0029148242
-
-
Skehel PA, Martin KC, Kandel ER, Bartsch D. A VAMP-binding protein from Aplysia required for neurotransmitter release. Science 1995; 269: 1580-1583.
-
Skehel PA, Martin KC, Kandel ER, Bartsch D. A VAMP-binding protein from Aplysia required for neurotransmitter release. Science 1995; 269: 1580-1583.
-
-
-
-
69
-
-
0033534788
-
Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins
-
Nishimura Y, Hayashi M, Inada H, Tanaka T. Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins. Biochem Biophys Res Commun 1999; 254: 21-26.
-
(1999)
Biochem Biophys Res Commun
, vol.254
, pp. 21-26
-
-
Nishimura, Y.1
Hayashi, M.2
Inada, H.3
Tanaka, T.4
-
70
-
-
0033967492
-
Mouse VAP33 is associated with the endoplasmic reticulum and microtubules
-
Skehel PA, Fabian-Fine R, Kandel ER. Mouse VAP33 is associated with the endoplasmic reticulum and microtubules. Proc Natl Acad Sci USA 2000; 97: 1101-1106.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1101-1106
-
-
Skehel, P.A.1
Fabian-Fine, R.2
Kandel, E.R.3
-
71
-
-
0033606771
-
ERG30, a VAP-33-related protein, functions in protein transport mediated by COPI vesicles
-
Soussan L, Burakov D, Daniels MP, et al. ERG30, a VAP-33-related protein, functions in protein transport mediated by COPI vesicles. J Cell Biol 1999; 146: 301-311.
-
(1999)
J Cell Biol
, vol.146
, pp. 301-311
-
-
Soussan, L.1
Burakov, D.2
Daniels, M.P.3
-
72
-
-
0031898053
-
The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism
-
Kagiwada S, Hosaka K, Murata M, Nikawa J, Takatsuki A. The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism. J Bacteriol 1998; 180: 1700-1708.
-
(1998)
J Bacteriol
, vol.180
, pp. 1700-1708
-
-
Kagiwada, S.1
Hosaka, K.2
Murata, M.3
Nikawa, J.4
Takatsuki, A.5
-
73
-
-
0032528227
-
Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): A broadly expressed protein that binds to VAMP
-
Weir ML, Klip A, Trimble WS. Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMP. Biochem J 1998; 333(Pt 2): 247-251.
-
(1998)
Biochem J
, vol.333
, Issue.PART 2
, pp. 247-251
-
-
Weir, M.L.1
Klip, A.2
Trimble, W.S.3
-
74
-
-
0019349945
-
Amoeboid motility and actin in Ascaris lumbricoides sperm
-
Nelson GA, Ward S. Amoeboid motility and actin in Ascaris lumbricoides sperm. Exp Cell Res 1981; 131: 149-160.
-
(1981)
Exp Cell Res
, vol.131
, pp. 149-160
-
-
Nelson, G.A.1
Ward, S.2
-
75
-
-
0035071303
-
How the assembly dynamics of the nematode major sperm protein generate amoeboid cell motility
-
Italiano JE Jr, Stewart M, Roberts TM. How the assembly dynamics of the nematode major sperm protein generate amoeboid cell motility. Int Rev Cytol 2001; 202: 1-34.
-
(2001)
Int Rev Cytol
, vol.202
, pp. 1-34
-
-
Italiano Jr, J.E.1
Stewart, M.2
Roberts, T.M.3
-
76
-
-
0034599633
-
Acting like actin. The dynamics of the nematode major sperm protein (msp) cytoskeleton indicate a push-pull mechanism for amoeboid cell motility
-
Roberts TM, Stewart M. Acting like actin. The dynamics of the nematode major sperm protein (msp) cytoskeleton indicate a push-pull mechanism for amoeboid cell motility. J Cell Biol 2000; 149: 7-12.
-
(2000)
J Cell Biol
, vol.149
, pp. 7-12
-
-
Roberts, T.M.1
Stewart, M.2
-
78
-
-
0038558194
-
A conserved ER targeting motif in three families of lipid binding proteins and in Opilp binds VAP
-
Loewen CJ, Roy A, Levine TP. A conserved ER targeting motif in three families of lipid binding proteins and in Opilp binds VAP. EMBO J 2003; 22: 2025-2035.
-
(2003)
EMBO J
, vol.22
, pp. 2025-2035
-
-
Loewen, C.J.1
Roy, A.2
Levine, T.P.3
-
79
-
-
0037130456
-
Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent manner
-
Pennetta G, Hiesinger PR, Fabian-Fine R, Meinertzhagen LA, Bellen HJ. Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent manner. Neuron 2002; 35: 291-306.
-
(2002)
Neuron
, vol.35
, pp. 291-306
-
-
Pennetta, G.1
Hiesinger, P.R.2
Fabian-Fine, R.3
Meinertzhagen, L.A.4
Bellen, H.J.5
-
81
-
-
21744460996
-
Structural basis of FFAT motif-mediated ER targeting
-
Kaiser SE, Brickner JH, Reilein AR, Fenn TD, Walter P, Brunger AT. Structural basis of FFAT motif-mediated ER targeting. Structure 2005; 13: 1035-1045.
-
(2005)
Structure
, vol.13
, pp. 1035-1045
-
-
Kaiser, S.E.1
Brickner, J.H.2
Reilein, A.R.3
Fenn, T.D.4
Walter, P.5
Brunger, A.T.6
-
82
-
-
14044266853
-
Gene recruitment of the activated INO1 locus to the nuclear membrane
-
Brickner JH, Walter P. Gene recruitment of the activated INO1 locus to the nuclear membrane. PLoS Biol 2004; 2: e342.
-
(2004)
PLoS Biol
, vol.2
-
-
Brickner, J.H.1
Walter, P.2
-
83
-
-
0034730746
-
Reconstitution of ATP- and cytosol-dependent transport of de novo synthesized ceramide to the site of sphingomyelin synthesis in semi-intact cells
-
Funakoshi T, Yasuda S, Fukasawa M, Nishijima M, Hanada K. Reconstitution of ATP- and cytosol-dependent transport of de novo synthesized ceramide to the site of sphingomyelin synthesis in semi-intact cells. J Biol Chem 2000; 275: 29938-29945.
-
(2000)
J Biol Chem
, vol.275
, pp. 29938-29945
-
-
Funakoshi, T.1
Yasuda, S.2
Fukasawa, M.3
Nishijima, M.4
Hanada, K.5
-
84
-
-
0033593788
-
Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells
-
Fukasawa M, Nishijima M, Hanada K. Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells. J Cell Biol 1999; 144: 673-685.
-
(1999)
J Cell Biol
, vol.144
, pp. 673-685
-
-
Fukasawa, M.1
Nishijima, M.2
Hanada, K.3
-
85
-
-
33749555280
-
Efficient trafficking of ceramide from the endoplas-mic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT
-
Kawano M, Kumagai K, Nishijima M, Hanada K. Efficient trafficking of ceramide from the endoplas-mic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT. J Biol Chem 2006; 281: 30279-30288.
-
(2006)
J Biol Chem
, vol.281
, pp. 30279-30288
-
-
Kawano, M.1
Kumagai, K.2
Nishijima, M.3
Hanada, K.4
-
86
-
-
34247117377
-
Hepatitis C virus NS5 A is a direct substrate of CKI-alpha, a cellular kinase identified by inhibitor affinity chromatography using specific NS5A hyperphosphorylation inhibitors
-
Quintavalle M, Sambucini S, Summa E, et al. Hepatitis C virus NS5 A is a direct substrate of CKI-alpha, a cellular kinase identified by inhibitor affinity chromatography using specific NS5A hyperphosphorylation inhibitors. J Biol Chem 2007; 282: 5536-5544.
-
(2007)
J Biol Chem
, vol.282
, pp. 5536-5544
-
-
Quintavalle, M.1
Sambucini, S.2
Summa, E.3
-
87
-
-
8644290077
-
Reduction of hepatitis C virus NS5A hyperphosphorylation by selective inhibition of cellular kinases activates viral RNA replication in cell culture
-
Neddermann P, Quintavalle M, Di Pietro C, et al. Reduction of hepatitis C virus NS5A hyperphosphorylation by selective inhibition of cellular kinases activates viral RNA replication in cell culture. J Virol 2004; 78: 13306-13314.
-
(2004)
J Virol
, vol.78
, pp. 13306-13314
-
-
Neddermann, P.1
Quintavalle, M.2
Di Pietro, C.3
-
88
-
-
30644465541
-
Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication
-
Burckstummer T, Kriegs M, Lupberger J, Pauli EK, Schmittel S, Hildt E. Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication. FEBS Lett 2006; 580: 575-580.
-
(2006)
FEBS Lett
, vol.580
, pp. 575-580
-
-
Burckstummer, T.1
Kriegs, M.2
Lupberger, J.3
Pauli, E.K.4
Schmittel, S.5
Hildt, E.6
-
89
-
-
1842457783
-
Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft
-
Gao L, Aizaki H, He JW, Lai MM. Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft. J Virol 2004; 78: 3480-3488.
-
(2004)
J Virol
, vol.78
, pp. 3480-3488
-
-
Gao, L.1
Aizaki, H.2
He, J.W.3
Lai, M.M.4
-
90
-
-
0037379425
-
Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that cofractionates with caveolin-2
-
Shi ST, Lee KJ, Aizaki H, Hwang SB, Lai MM. Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that cofractionates with caveolin-2. J Virol 2003; 77: 4160-4168.
-
(2003)
J Virol
, vol.77
, pp. 4160-4168
-
-
Shi, S.T.1
Lee, K.J.2
Aizaki, H.3
Hwang, S.B.4
Lai, M.M.5
-
91
-
-
1542330798
-
Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus
-
Zhang J, Yamada O, Sakamoto T, et al. Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus. Virology 2004; 320: 135-143.
-
(2004)
Virology
, vol.320
, pp. 135-143
-
-
Zhang, J.1
Yamada, O.2
Sakamoto, T.3
-
92
-
-
14044268935
-
Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction
-
Amarilio R, Ramachandran S, Sabanay H, Lev S. Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction. J Biol Chem 2005; 280: 5934-5944.
-
(2005)
J Biol Chem
, vol.280
, pp. 5934-5944
-
-
Amarilio, R.1
Ramachandran, S.2
Sabanay, H.3
Lev, S.4
-
93
-
-
33750614324
-
Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef
-
Giese SI, Woerz I, Homann S, Tibroni N, Geyer M, Fackler OT. Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef. Virology 2006; 355: 175-191.
-
(2006)
Virology
, vol.355
, pp. 175-191
-
-
Giese, S.I.1
Woerz, I.2
Homann, S.3
Tibroni, N.4
Geyer, M.5
Fackler, O.T.6
-
94
-
-
33644539188
-
The HIV lipidome: A raft with an unusual composition
-
Brugger B, Glass B, Haberkant P, Leibrecht I, Wieland FT, Krausslich HG. The HIV lipidome: a raft with an unusual composition. Proc Natl Acad Sci USA 2006; 103: 2641-2646.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2641-2646
-
-
Brugger, B.1
Glass, B.2
Haberkant, P.3
Leibrecht, I.4
Wieland, F.T.5
Krausslich, H.G.6
-
95
-
-
33846014643
-
Modification of host lipid raft proteome upon hepatitis C virus replication
-
Mannova P, Fang R, Wang H, et al. Modification of host lipid raft proteome upon hepatitis C virus replication. Mol Cell Proteomics 2006; 5: 2319-2325.
-
(2006)
Mol Cell Proteomics
, vol.5
, pp. 2319-2325
-
-
Mannova, P.1
Fang, R.2
Wang, H.3
-
96
-
-
33750317434
-
The cytoplasmic tail of the human respiratory syncytial virus F protein plays critical roles in cellular localization of the F protein and infectious progeny production
-
Oomens AG, Bevis KP, Wertz GW. The cytoplasmic tail of the human respiratory syncytial virus F protein plays critical roles in cellular localization of the F protein and infectious progeny production. J Virol 2006; 80: 10465-10477.
-
(2006)
J Virol
, vol.80
, pp. 10465-10477
-
-
Oomens, A.G.1
Bevis, K.P.2
Wertz, G.W.3
-
97
-
-
27144533145
-
Influenza virus hemagglutinin (H3 subtype) requires palmitoylation of its cytoplasmic tail for assembly: M1 proteins of two subtypes differ in their ability to support assembly
-
Chen BJ, Takeda M, Lamb RA. Influenza virus hemagglutinin (H3 subtype) requires palmitoylation of its cytoplasmic tail for assembly: M1 proteins of two subtypes differ in their ability to support assembly. J Virol 2005; 79: 13673-13684.
-
(2005)
J Virol
, vol.79
, pp. 13673-13684
-
-
Chen, B.J.1
Takeda, M.2
Lamb, R.A.3
-
98
-
-
14044265120
-
Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids
-
Kapadia SB, Chisari FV. Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids. Proc Natl Acad Sci USA 2005; 102: 2561-2566.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2561-2566
-
-
Kapadia, S.B.1
Chisari, F.V.2
-
99
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 2002; 109: 1125-1131.
-
(2002)
J Clin Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
100
-
-
11144357274
-
Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets
-
Barba G, Harper F, Harada T, et al. Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets. Proc Natl Acad Sci USA 1997; 94: 1200-1205.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1200-1205
-
-
Barba, G.1
Harper, F.2
Harada, T.3
-
101
-
-
33846850496
-
Critical role of PA28gamma in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis
-
Moriishi K, Mochizuki R, Moriya K, et al. Critical role of PA28gamma in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis. Proc Natl Acad Sci USA 2007; 104: 1661-1666.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 1661-1666
-
-
Moriishi, K.1
Mochizuki, R.2
Moriya, K.3
-
102
-
-
2942715265
-
Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts
-
Aizaki H, Lee KJ, Sung VM, Ishiko H, Lai MM. Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts. Virology 2004; 324: 450-461.
-
(2004)
Virology
, vol.324
, pp. 450-461
-
-
Aizaki, H.1
Lee, K.J.2
Sung, V.M.3
Ishiko, H.4
Lai, M.M.5
-
103
-
-
0346103657
-
Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation
-
Ye J, Wang C, Sumpter R Jr, Brown MS, Goldstein JL, Gale M Jr. Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation. Proc Natl Acad Sci USA 2003; 100: 15865-15870.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15865-15870
-
-
Ye, J.1
Wang, C.2
Sumpter Jr, R.3
Brown, M.S.4
Goldstein, J.L.5
Gale Jr., M.6
-
104
-
-
18944366522
-
Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication
-
Wang C, Gale M Jr, Keller BC, et al. Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication. Mol Cell 2005; 18: 425-434.
-
(2005)
Mol Cell
, vol.18
, pp. 425-434
-
-
Wang, C.1
Gale Jr, M.2
Keller, B.C.3
-
105
-
-
0032849815
-
Identification of a novel Skp2-like mammalian protein containing F-box and leucine-rich repeats
-
Ilyin GP, Rialland M, Glaise D, Guguen-Guillouzo C. Identification of a novel Skp2-like mammalian protein containing F-box and leucine-rich repeats. FEBS Lett 1999; 459: 75-79.
-
(1999)
FEBS Lett
, vol.459
, pp. 75-79
-
-
Ilyin, G.P.1
Rialland, M.2
Glaise, D.3
Guguen-Guillouzo, C.4
-
106
-
-
33645227630
-
Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon
-
Shimakami T, Honda M, Kusakawa T, et al. Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon. J Virol 2006; 80: 3332-3340.
-
(2006)
J Virol
, vol.80
, pp. 3332-3340
-
-
Shimakami, T.1
Honda, M.2
Kusakawa, T.3
-
107
-
-
2342642869
-
Cellular RNA helicase p68 relocalization and interaction with the hepatitis C virus (HCV) NS5B protein and the potential role of p68 in HCV RNA replication
-
Goh PY, Tan YJ, Lim SP, et al. Cellular RNA helicase p68 relocalization and interaction with the hepatitis C virus (HCV) NS5B protein and the potential role of p68 in HCV RNA replication. J Virol 2004; 78: 5288-5298.
-
(2004)
J Virol
, vol.78
, pp. 5288-5298
-
-
Goh, P.Y.1
Tan, Y.J.2
Lim, S.P.3
-
108
-
-
33745797050
-
Hepatitis C virus triggers mitochondrial permeability transition with production of reactive oxygen species, leading to DNA damage and STAT3 activation
-
Machida K, Cheng KT, Lai CK, Jeng KS, Sung VM, Lai MM. Hepatitis C virus triggers mitochondrial permeability transition with production of reactive oxygen species, leading to DNA damage and STAT3 activation. J Virol 2006; 80: 7199-7207.
-
(2006)
J Virol
, vol.80
, pp. 7199-7207
-
-
Machida, K.1
Cheng, K.T.2
Lai, C.K.3
Jeng, K.S.4
Sung, V.M.5
Lai, M.M.6
-
109
-
-
33750629784
-
HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice
-
Kawamura H, Govindarajan S, Aswad F, et al. HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice. Hepatology 2006; 44: 936-944.
-
(2006)
Hepatology
, vol.44
, pp. 936-944
-
-
Kawamura, H.1
Govindarajan, S.2
Aswad, F.3
-
110
-
-
0036717295
-
Activation of STAT3 by the hepatitis C virus core protein leads to cellular transformation
-
Yoshida T, Hanada T, Tokuhisa T, et al. Activation of STAT3 by the hepatitis C virus core protein leads to cellular transformation. J Exp Med 2002; 196: 641-653.
-
(2002)
J Exp Med
, vol.196
, pp. 641-653
-
-
Yoshida, T.1
Hanada, T.2
Tokuhisa, T.3
-
111
-
-
33745750797
-
Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis
-
Ogata H, Kobayashi T, Chinen T, et al. Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis. Gastroenterology 2006; 131: 179-193.
-
(2006)
Gastroenterology
, vol.131
, pp. 179-193
-
-
Ogata, H.1
Kobayashi, T.2
Chinen, T.3
-
112
-
-
0031712813
-
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
-
Moriya K, Fujie H, Shintani Y, et al. The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med 1998; 4: 1065-1067.
-
(1998)
Nat Med
, vol.4
, pp. 1065-1067
-
-
Moriya, K.1
Fujie, H.2
Shintani, Y.3
-
113
-
-
0036158719
-
Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus
-
Lerat H, Honda M, Beard MR, et al. Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology 2002; 122: 352-365.
-
(2002)
Gastroenterology
, vol.122
, pp. 352-365
-
-
Lerat, H.1
Honda, M.2
Beard, M.R.3
-
114
-
-
0031034119
-
Sialadenitis histologically resembling Sjogren syndrome in mice transgenic for hepatitis C virus envelope genes
-
Koike K, Moriya K, Ishibashi K, et al. Sialadenitis histologically resembling Sjogren syndrome in mice transgenic for hepatitis C virus envelope genes. Proc Natl Acad Sci USA 1997; 94: 233-236.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 233-236
-
-
Koike, K.1
Moriya, K.2
Ishibashi, K.3
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