Fkbp8: Novel isoforms, genomic organization, and characterization of a forebrain promoter in transgenic mice

Genomics

Volumn 83, Issue 1, 2004, Pages 181-192

  Nielsen, Jakob V ^a   Mitchelmore, Cathy ^a   Pedersen, Karen M ^a   Kjærulff, Karen M ^a   Finsen, Bente ^b   Jensen, Niels A ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

FKBP38; FKBP8; Forebrain; Hippocampus; Immunophilin; Neurons; Promoter; Transgenic mice

Indexed keywords

BETA GALACTOSIDASE; ISOPROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CIS TRANS ISOMERISM; CONTIG MAPPING; CONTROLLED STUDY; EXON; FOREBRAIN; GC RICH SEQUENCE; GENE IDENTIFICATION; GENE INSERTION; GENE STRUCTURE; GENETIC CODE; HIPPOCAMPUS; HUMAN VERSUS ANIMAL COMPARISON; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMORPHIC LOCUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; REPORTER GENE; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

MURINAE; MUS MUSCULUS;

EID: 0345550284     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ygeno.2003.07.001     Document Type: Article

References (27)

1. Hamilton G.S., Steiner J.P. Immunophilins: beyond immunosuppression. J. Med. Chem. 41:1998;5119-5143.
2. Gothel S.F., Marahiel M.A. Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts. Cell. Mol. Life Sci. 55:1999;423-436.
3. Snyder S.H.et al. Neural actions of immunophilin ligands. Trends Pharmacol. Sci. 19:1998;21-26.
4. Steiner J.P.et al. Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A. Nat. Med. 3:1997;421-428.
5. Galat A. Sequence diversification of the FK506-binding proteins in several different genomes. Eur. J. Biochem. 267:2000;4945-4959.
6. Himukai R., Kuzuhara T., Horikoshi M. Relationship between the subcellular localization and structures of catalytic domains of FKBP-type PPIases. J. Biochem. (Tokyo). 126:1999;879-888.
7. Shou W.et al. Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12. Nature. 391:1998;489-492.
8. Xin H.B.et al. Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy. Nature. 416:2002;334-338.
9. Peattie D.A.et al. Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes. Proc. Natl. Acad. Sci. USA. 89:1992;10974-10978.
10. Pirkl F., Buchner J. Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40. J. Mol. Biol. 308:2001;795-806.
11. Shirane M., Nakayama K.I. Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis. Nat. Cell Biol. 5:2003;28-37.
12. Pedersen K.M., Finsen B., Celis J.E., Jensen N.A. muFKBP38: a novel murine immunophilin homolog differentially expressed in Schwannoma cells and central nervous system neurons in vivo. Electrophoresis. 20:1999;249-255.
13. Lam E., Martin M., Wiederrecht G. Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs. Gene. 160:1995;297-302.
14. Mount S.M. A catalogue of splice junction sequences. Nucleic Acids Res. 10:1982;459-472.
15. Burset M., Seledtsov I.A., Solovyev V.V. Analysis of canonical and non-canonical splice sites in mammalian genomes. Nucleic Acids Res. 28:2000;4364-4375.
16. Quandt K., Frech K., Karas H., Wingender E., Werner T. MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23:1995;4878-4884.
17. Sola C., Tusell J.M., Serratosa J. Comparative study of the distribution of calmodulin kinase II and calcineurin in the mouse brain. J. Neurosci. Res. 57:1999;651-662.
18. Asai A.et al. High level calcineurin activity predisposes neuronal cells to apoptosis. J. Biol. Chem. 274:1999;34450-34458.
19. 2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science. 284:1999;339-343.
20. Blatch G.L., Lassle M. The tetratricopeptide repeat: a structural motif mediating protein-protein interactions. Bioessays. 21:1999;932-939.
21. Radanyi C., Chambraud B., Baulieu E.E. The ability of the immunophilin FKBP59-HBI to interact with the 90-kDa heat shock protein is encoded by its tetratricopeptide repeat domain. Proc. Natl. Acad. Sci. USA. 91:1994;11197-11201.
22. Mantovani R. A survey of 178 NF-Y binding CCAAT boxes. Nucleic Acids Res. 26:1998;1135-1143.
23. Beckmann A.M., Wilce P.A. Egr transcription factors in the nervous system. Neurochem. Int. 31:1997;477-510.
24. Hughes P., Lawlor P., Dragunow M. Basal expression of Fos, Fos-related, Jun, and Krox 24 proteins in rat hippocampus. Brain Res. Mol. Brain Res. 13:1992;355-357.
25. Chirgwin J.M., Przybyla A.E., MacDonald R.J., Rutter W.J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
26. Mountford P.et al. Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc. Natl. Acad. Sci. USA. 91:1994;4303-4307.
27. Jensen N.A., Smith G.M., Shine H.D., Garvey J.S., Hood L. Distinct hypomyelinated phenotypes in MBP-SV40 large T transgenic mice. J. Neurosci. Res. 34:1993;257-264.