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Volumn 371, Issue , 2007, Pages 45-72

Telomere length analysis

Author keywords

Aging; Cancer; DNA damage; Telomerase; Telomeres

Indexed keywords

BIOLOGICAL MARKER;

EID: 34548774526     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1385/1-59745-361-7:45     Document Type: Article
Times cited : (40)

References (62)
  • 1
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn, E. H. (2001) Switching and signaling at the telomere. Cell 106, 661-673.
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 2
    • 1842683257 scopus 로고    scopus 로고
    • T-loops and the origin of telomeres
    • de Lange, T. (2004) T-loops and the origin of telomeres. Nat. Rev. Mol. Cell Biol. 5, 323-329.
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 323-329
    • de Lange, T.1
  • 3
    • 0037102234 scopus 로고    scopus 로고
    • Smogorzewska, A. and de Lange, T. (2002) Different telomere damage signaling pathways in human and mouse cells. EMBO J. 21, 43384348.
    • Smogorzewska, A. and de Lange, T. (2002) Different telomere damage signaling pathways in human and mouse cells. EMBO J. 21, 43384348.
  • 4
    • 0344441890 scopus 로고    scopus 로고
    • A DNA damage checkpoint response in telomere-initiated senescence
    • d'Adda di Fagagna, F., Reaper, P. M., Clay-Farrace, L., et al. (2003) A DNA damage checkpoint response in telomere-initiated senescence. Nature 426, 194-198.
    • (2003) Nature , vol.426 , pp. 194-198
    • d'Adda di Fagagna, F.1    Reaper, P.M.2    Clay-Farrace, L.3
  • 5
    • 0042420304 scopus 로고    scopus 로고
    • DNA damage foci at dysfunctional telomeres
    • Takai, H., Smogorzewska, A., and de Lange, T. (2003) DNA damage foci at dysfunctional telomeres. Curr. Biol. 13, 1549-1556.
    • (2003) Curr. Biol , vol.13 , pp. 1549-1556
    • Takai, H.1    Smogorzewska, A.2    de Lange, T.3
  • 6
    • 0015844590 scopus 로고
    • A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
    • Olovnikov, A. M. (1973) A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. J. Theor. Biol. 41, 181-190.
    • (1973) J. Theor. Biol , vol.41 , pp. 181-190
    • Olovnikov, A.M.1
  • 7
    • 19844382620 scopus 로고    scopus 로고
    • Senescence and immortalization: Role of telomeres and telomerase
    • Shay, J. W. and Wright, W. E. (2005) Senescence and immortalization: role of telomeres and telomerase. Carcinogenesis 26, 867-874.
    • (2005) Carcinogenesis , vol.26 , pp. 867-874
    • Shay, J.W.1    Wright, W.E.2
  • 8
    • 0037148271 scopus 로고    scopus 로고
    • Telomerase in the human organism
    • Collins, K. and Mitchell, J. R. (2002) Telomerase in the human organism. Oncogene 21, 564-579.
    • (2002) Oncogene , vol.21 , pp. 564-579
    • Collins, K.1    Mitchell, J.R.2
  • 9
    • 0026460896 scopus 로고
    • Telomere length predicts replicative capacity of human fibroblasts
    • 10, 118
    • Allsopp, R. C., Vaziri, H., Patterson, C., et al. ( 1992) Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl. Acad. Sci. USA 89, 10, 114-10, 118.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 114-110
    • Allsopp, R.C.1    Vaziri, H.2    Patterson, C.3
  • 11
    • 0033816392 scopus 로고    scopus 로고
    • Telomere attrition of the human abdominal aorta: Relationships with age and atherosclerosis
    • Okuda, K., Khan, M. Y., Skurnick, J., Kimura, M., Aviv, H., and Aviv, A. (2000) Telomere attrition of the human abdominal aorta: relationships with age and atherosclerosis. Atherosclerosis 152, 391-398.
    • (2000) Atherosclerosis , vol.152 , pp. 391-398
    • Okuda, K.1    Khan, M.Y.2    Skurnick, J.3    Kimura, M.4    Aviv, H.5    Aviv, A.6
  • 12
    • 0031913921 scopus 로고    scopus 로고
    • Shortened telomere length in white blood cells of patients with IDDM
    • Jeanclos, E., Krolewski, A., Skurnick, J., et al. (1998) Shortened telomere length in white blood cells of patients with IDDM. Diabetes 47, 482-486.
    • (1998) Diabetes , vol.47 , pp. 482-486
    • Jeanclos, E.1    Krolewski, A.2    Skurnick, J.3
  • 13
    • 0030881301 scopus 로고    scopus 로고
    • Replicative potential and telomere length in human skeletal muscle: Implications for satellite cell-mediated gene therapy
    • Decary, S., Mouly, V., Hamida, C. B., Sautet, A., Barbet, J. P., and Butler-Browne, G. S. (1997) Replicative potential and telomere length in human skeletal muscle: implications for satellite cell-mediated gene therapy. Hum. Gene Ther. 8, 1429-1438.
    • (1997) Hum. Gene Ther , vol.8 , pp. 1429-1438
    • Decary, S.1    Mouly, V.2    Hamida, C.B.3    Sautet, A.4    Barbet, J.P.5    Butler-Browne, G.S.6
  • 14
    • 0029872174 scopus 로고    scopus 로고
    • Telomerase activity in human germline and embryonic tissues and cells
    • Wright, W. E., Piatyszek, M. A., Rainey, W E., Byrd, W., and Shay, J. W. (1996) Telomerase activity in human germline and embryonic tissues and cells. Dev. Genet. 18, 173-179.
    • (1996) Dev. Genet , vol.18 , pp. 173-179
    • Wright, W.E.1    Piatyszek, M.A.2    Rainey, W.E.3    Byrd, W.4    Shay, J.W.5
  • 15
    • 0033747604 scopus 로고    scopus 로고
    • Short telomeres in patients with vascular dementia: An indicator of low antioxidative capacity and a possible risk factor?
    • von Zglinicki, T., Serra, V., Lorenz, M., et al. (2000) Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor? Lab. Invest. 80, 1739-1747.
    • (2000) Lab. Invest , vol.80 , pp. 1739-1747
    • von Zglinicki, T.1    Serra, V.2    Lorenz, M.3
  • 17
    • 0042140590 scopus 로고    scopus 로고
    • Telomere dysfunction: A potential cancer predisposition factor
    • Wu, X., Amos, C. I., Zhu, Y., et al. (2003) Telomere dysfunction: a potential cancer predisposition factor. J. Natl. Cancer Inst. 95, 1211-1218.
    • (2003) J. Natl. Cancer Inst , vol.95 , pp. 1211-1218
    • Wu, X.1    Amos, C.I.2    Zhu, Y.3
  • 18
    • 0030931491 scopus 로고    scopus 로고
    • Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
    • Blasco, M. A., Lee, H. W., Hande, M. P., et al. (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91, 25-34.
    • (1997) Cell , vol.91 , pp. 25-34
    • Blasco, M.A.1    Lee, H.W.2    Hande, M.P.3
  • 20
    • 0033153424 scopus 로고    scopus 로고
    • Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
    • Herrera, E., Samper, E., Martin-Caballero, J., Flores, J. M., Lee, H. W and Blasco, M. A. (1999) Disease states associated with telomerase deficiency appear earlier in mice with short telomeres. EMBO J. 18, 2950-2960.
    • (1999) EMBO J , vol.18 , pp. 2950-2960
    • Herrera, E.1    Samper, E.2    Martin-Caballero, J.3    Flores, J.M.4    Lee, H.W.5    Blasco, M.A.6
  • 21
    • 0343750697 scopus 로고    scopus 로고
    • Impaired germinal center reaction in mice with short telomeres
    • Herrera, E., Martinez, A. C., and Blasco, M. A. (2000) Impaired germinal center reaction in mice with short telomeres. EMBO J. 19, 472-481.
    • (2000) EMBO J , vol.19 , pp. 472-481
    • Herrera, E.1    Martinez, A.C.2    Blasco, M.A.3
  • 22
    • 0033104511 scopus 로고    scopus 로고
    • Telomere shortening in mTR-/-embryos is associated with failure to close the neural tube
    • Herrera, E., Samper, E., and Blasco, M.A. (1999) Telomere shortening in mTR-/-embryos is associated with failure to close the neural tube. EMBO J. 18, 1172-1181.
    • (1999) EMBO J , vol.18 , pp. 1172-1181
    • Herrera, E.1    Samper, E.2    Blasco, M.A.3
  • 23
    • 0033525558 scopus 로고    scopus 로고
    • Longevity, stress response, and cancer in aging telomerase-deficient mice
    • Rudolph, K. L., Chang, S., Lee, H. W., et al. (1999) Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96, 701-712.
    • (1999) Cell , vol.96 , pp. 701-712
    • Rudolph, K.L.1    Chang, S.2    Lee, H.W.3
  • 24
    • 0037081078 scopus 로고    scopus 로고
    • Decreased B16F10 melanoma growth and impaired vascularization in telomerase-deficient mice with critically short telomeres
    • Franco, S., Segura, I., Riese, H. H., and Blasco, M. A. (2002) Decreased B16F10 melanoma growth and impaired vascularization in telomerase-deficient mice with critically short telomeres. Cancer Res. 62, 552-559.
    • (2002) Cancer Res , vol.62 , pp. 552-559
    • Franco, S.1    Segura, I.2    Riese, H.H.3    Blasco, M.A.4
  • 25
    • 0037089438 scopus 로고    scopus 로고
    • Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells
    • Samper, E., Fernandez, P., Eguia, R., et al. (2002) Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells. Blood 99, 2767-2775.
    • (2002) Blood , vol.99 , pp. 2767-2775
    • Samper, E.1    Fernandez, P.2    Eguia, R.3
  • 26
    • 0037413726 scopus 로고    scopus 로고
    • Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation
    • Leri, A., Franco, S., Zacheo, A., et al. (2003) Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation. EMBOJ. 22, 131-139.
    • (2003) EMBOJ , vol.22 , pp. 131-139
    • Leri, A.1    Franco, S.2    Zacheo, A.3
  • 27
    • 0025787643 scopus 로고
    • Telomere loss: Mitotic clock or genetic time bomb?
    • Harley, C. B. (1991) Telomere loss: mitotic clock or genetic time bomb? Mutat. Res. 256, 271-282.
    • (1991) Mutat. Res , vol.256 , pp. 271-282
    • Harley, C.B.1
  • 28
    • 0001934324 scopus 로고
    • Telomeres and aging
    • Blackburn, E. H. and Greider, C. W, eds, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY: pp
    • Harley, C. B. (1995) Telomeres and aging, in Telomeres (Blackburn, E. H. and Greider, C. W., eds.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY: pp. 247-264.
    • (1995) Telomeres , pp. 247-264
    • Harley, C.B.1
  • 29
    • 0032864304 scopus 로고    scopus 로고
    • Simple, rapid, quantitative, and sensitive detection of telomere repeats in cell lysate by a hybridization protection assay
    • Nakamura, Y., Hirose, M., Matsuo, H., Tsuyama, N., Kamisango, K., and Ide, T. (1999) Simple, rapid, quantitative, and sensitive detection of telomere repeats in cell lysate by a hybridization protection assay. Clin. Chem. 45, 1718-1724.
    • (1999) Clin. Chem , vol.45 , pp. 1718-1724
    • Nakamura, Y.1    Hirose, M.2    Matsuo, H.3    Tsuyama, N.4    Kamisango, K.5    Ide, T.6
  • 32
    • 0037313185 scopus 로고    scopus 로고
    • Extensive allelic variation and ultrashort telomeres in senescent human cells
    • Baird, D. M., Rowson, J., Wynford-Thomas, D., and Kipling, D. (2003) Extensive allelic variation and ultrashort telomeres in senescent human cells. Nat. Genet. 33, 203-207.
    • (2003) Nat. Genet , vol.33 , pp. 203-207
    • Baird, D.M.1    Rowson, J.2    Wynford-Thomas, D.3    Kipling, D.4
  • 33
    • 0013462065 scopus 로고
    • A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes
    • Moyzis, R. K., Buckingham, J. M., Cram, L. S., et al. (1988) A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proc. Natl. Acad. Sci. USA 85, 6622-6626.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6622-6626
    • Moyzis, R.K.1    Buckingham, J.M.2    Cram, L.S.3
  • 34
    • 0023941599 scopus 로고
    • Telomeric repeat from T. thermophila cross hybridizes with human telomeres
    • Allshire, R. C., Gosden, J. R., Cross, S. H., et al. (1988) Telomeric repeat from T. thermophila cross hybridizes with human telomeres. Nature 332, 656-659.
    • (1988) Nature , vol.332 , pp. 656-659
    • Allshire, R.C.1    Gosden, J.R.2    Cross, S.H.3
  • 35
    • 0025029030 scopus 로고
    • Hypervariable ultra-long telomeres in mice
    • Kipling, D. and Cooke, H. J. (1990) Hypervariable ultra-long telomeres in mice. Nature 347, 400-402.
    • (1990) Nature , vol.347 , pp. 400-402
    • Kipling, D.1    Cooke, H.J.2
  • 36
    • 0033569847 scopus 로고    scopus 로고
    • G-strand overhangs on telomeres in telomerase-deficient mouse cells
    • Hemann, M. T. and Greider, C. W. (1999) G-strand overhangs on telomeres in telomerase-deficient mouse cells. Nucleic Acids Res. 27, 3964-3969.
    • (1999) Nucleic Acids Res , vol.27 , pp. 3964-3969
    • Hemann, M.T.1    Greider, C.W.2
  • 37
    • 0029939848 scopus 로고    scopus 로고
    • Heterogeneity in telomere length of human chromosomes
    • Lansdorp, P. M., Verwoerd, N. P., van de Rijke, F. M., et al. (1996) Heterogeneity in telomere length of human chromosomes. Hum. Mol. Genet. 5, 685-691.
    • (1996) Hum. Mol. Genet , vol.5 , pp. 685-691
    • Lansdorp, P.M.1    Verwoerd, N.P.2    van de Rijke, F.M.3
  • 38
    • 0026341239 scopus 로고
    • Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide
    • Nielsen, P. E., Egholm, M., Berg, R. H., and Buchardt, O. (1991) Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science 254, 1497-1500.
    • (1991) Science , vol.254 , pp. 1497-1500
    • Nielsen, P.E.1    Egholm, M.2    Berg, R.H.3    Buchardt, O.4
  • 39
    • 0027364174 scopus 로고
    • PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules
    • Egholm, M., Buchardt, O., Christensen, L., et al. (1993) PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature 365, 566-568.
    • (1993) Nature , vol.365 , pp. 566-568
    • Egholm, M.1    Buchardt, O.2    Christensen, L.3
  • 40
    • 0033178240 scopus 로고    scopus 로고
    • Telomere length measurements using digital fluorescence microscopy
    • Poon, S. S., Martens, U. M., Ward, R. K., and Lansdorp, P. M. (1999) Telomere length measurements using digital fluorescence microscopy. Cytometry 36, 267-278.
    • (1999) Cytometry , vol.36 , pp. 267-278
    • Poon, S.S.1    Martens, U.M.2    Ward, R.K.3    Lansdorp, P.M.4
  • 41
    • 0030737882 scopus 로고    scopus 로고
    • Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats
    • Zijlmans, J. M., Martens, U. M., Poon, S. S., et al. (1997) Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats. Proc. Natl. Acad. Sci. USA 94, 7423-7428.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7423-7428
    • Zijlmans, J.M.1    Martens, U.M.2    Poon, S.S.3
  • 42
    • 0031984598 scopus 로고    scopus 로고
    • Short telomeres on human chromosome 17p
    • Martens, U. M., Zijlmans, J. M., Poon, S. S., et al. (1998) Short telomeres on human chromosome 17p. Nat. Genet. 18, 76-80.
    • (1998) Nat. Genet , vol.18 , pp. 76-80
    • Martens, U.M.1    Zijlmans, J.M.2    Poon, S.S.3
  • 43
    • 0034769105 scopus 로고    scopus 로고
    • Restoration of telomerase activity rescues chromosomal instability and premature aging in Tere-/- mice with short telomeres
    • Samper, E., Flores, J. M., and Blasco, M. A. (2001) Restoration of telomerase activity rescues chromosomal instability and premature aging in Tere-/- mice with short telomeres. EMBO Rep. 2, 800-807.
    • (2001) EMBO Rep , vol.2 , pp. 800-807
    • Samper, E.1    Flores, J.M.2    Blasco, M.A.3
  • 44
    • 0035812845 scopus 로고    scopus 로고
    • The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
    • Hemann, M. T., Strong, M. A., Hao, L. Y., and Greider, C.W. (2001) The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107, 67-77.
    • (2001) Cell , vol.107 , pp. 67-77
    • Hemann, M.T.1    Strong, M.A.2    Hao, L.Y.3    Greider, C.W.4
  • 45
    • 3342972121 scopus 로고    scopus 로고
    • Does a sentinel or a subset of short telomeres determine replicative senescence?
    • Zou, Y., Sfeir, A., Gryaznov, S. M., Shay, J. W., and Wright, W. E. (2004) Does a sentinel or a subset of short telomeres determine replicative senescence? MoL Biol. Cell 15, 3709-3718.
    • (2004) MoL Biol. Cell , vol.15 , pp. 3709-3718
    • Zou, Y.1    Sfeir, A.2    Gryaznov, S.M.3    Shay, J.W.4    Wright, W.E.5
  • 46
    • 0028557213 scopus 로고
    • Stringent sequence requirements for the formation of human telomeres
    • Hanish, J. P., Yanowitz, J. L., and de Lange, T. (1994) Stringent sequence requirements for the formation of human telomeres. Proc. Natl. Acad. Sci. USA 91, 8861-8865.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8861-8865
    • Hanish, J.P.1    Yanowitz, J.L.2    de Lange, T.3
  • 47
    • 0035117940 scopus 로고    scopus 로고
    • Telomere length abnormalities in mammalian radiosensitive cells
    • McIlrath, J., Bouffier, S. D., Samper, E., et al. (2001) Telomere length abnormalities in mammalian radiosensitive cells. Cancer Res. 61, 912-915.
    • (2001) Cancer Res , vol.61 , pp. 912-915
    • McIlrath, J.1    Bouffier, S.D.2    Samper, E.3
  • 48
    • 0343228751 scopus 로고    scopus 로고
    • Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
    • Gonzalez-Suarez, E., Samper, E., Flores, J. M., and Blasco, M. A. (2000) Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat. Genet. 26, 114-117.
    • (2000) Nat. Genet , vol.26 , pp. 114-117
    • Gonzalez-Suarez, E.1    Samper, E.2    Flores, J.M.3    Blasco, M.A.4
  • 49
    • 0035130130 scopus 로고    scopus 로고
    • Telomere associations in interphase nuclei: Possible role in maintenance of interphase chromosome topology
    • Nagele, R. G., Velasco, A. Q., Anderson, W J., et al. (2001) Telomere associations in interphase nuclei: possible role in maintenance of interphase chromosome topology. J. Cell Sci. 114, 377-388.
    • (2001) J. Cell Sci , vol.114 , pp. 377-388
    • Nagele, R.G.1    Velasco, A.Q.2    Anderson, W.J.3
  • 50
    • 27144515686 scopus 로고    scopus 로고
    • XPF nucleasedependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer
    • Munoz, P., Blanco, R., Flores, J. M., and Blasco, M. A. (2005) XPF nucleasedependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer. Nat. Genet. 37, 1063-1071.
    • (2005) Nat. Genet , vol.37 , pp. 1063-1071
    • Munoz, P.1    Blanco, R.2    Flores, J.M.3    Blasco, M.A.4
  • 51
    • 0031879115 scopus 로고    scopus 로고
    • Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
    • Rufer, N., Dragowska, W, Thornbury, G., Roosnek, E., and Lansdorp, P. M. (1998) Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nat. Biotechnol. 16, 743-747.
    • (1998) Nat. Biotechnol , vol.16 , pp. 743-747
    • Rufer, N.1    Dragowska, W.2    Thornbury, G.3    Roosnek, E.4    Lansdorp, P.M.5
  • 53
    • 0035166456 scopus 로고    scopus 로고
    • Simultaneous flow cytometric analysis of cell surface markers and telomere length: Analysis of human tonsilar B cells
    • Batliwalla, F. M., Damle, R. N., Metz, C., Chiorazzi, N., and Gregersen, P.K. (2001) Simultaneous flow cytometric analysis of cell surface markers and telomere length: analysis of human tonsilar B cells. J. Immunol. Methods 247, 103-109.
    • (2001) J. Immunol. Methods , vol.247 , pp. 103-109
    • Batliwalla, F.M.1    Damle, R.N.2    Metz, C.3    Chiorazzi, N.4    Gregersen, P.K.5
  • 54
    • 0142205623 scopus 로고    scopus 로고
    • Telomere length measurements in leukocyte subsets by automated multicolor flow-FISH
    • Baerlocher, G. M. and Lansdorp, P. M. (2003) Telomere length measurements in leukocyte subsets by automated multicolor flow-FISH. Cytometry A 55, 1-6.
    • (2003) Cytometry A , vol.55 , pp. 1-6
    • Baerlocher, G.M.1    Lansdorp, P.M.2
  • 55
    • 0030704703 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization with a synthetic (T2AG3)n polynucleotide detects several intrachromosomal telomere-like repeats on human chromosomes
    • Azzalin, C. M., Mucciolo, E., Bertoni, L., and Giulotto, E. (1997) Fluorescence in situ hybridization with a synthetic (T2AG3)n polynucleotide detects several intrachromosomal telomere-like repeats on human chromosomes. Cytogenet. Cell Genet. 78, 112-115.
    • (1997) Cytogenet. Cell Genet , vol.78 , pp. 112-115
    • Azzalin, C.M.1    Mucciolo, E.2    Bertoni, L.3    Giulotto, E.4
  • 56
    • 0034616215 scopus 로고    scopus 로고
    • Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase
    • Ouellette, M. M., Liao, M., Herbert, B. S., et al. (2000) Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase. J. Biol. Chem. 275, 10,072-10,076.
    • (2000) J. Biol. Chem , vol.275
    • Ouellette, M.M.1    Liao, M.2    Herbert, B.S.3
  • 57
    • 0035985289 scopus 로고    scopus 로고
    • Mammalian meiotic telomeres: Composition and ultrastructure in telomerase-deficient mice
    • Franco, S., Alsheimer, M., Herrera, E., Benavente, R., and Blasco, M. A. (2002) Mammalian meiotic telomeres: composition and ultrastructure in telomerase-deficient mice. Eur. J. Cell Biol. 81, 335-340.
    • (2002) Eur. J. Cell Biol , vol.81 , pp. 335-340
    • Franco, S.1    Alsheimer, M.2    Herrera, E.3    Benavente, R.4    Blasco, M.A.5
  • 58
    • 0347988045 scopus 로고    scopus 로고
    • Epigenetic regulation of telomere length in mammalian cells by the Suv39hl and Suv39h2 histone methyltransferases
    • Garcia-Cao, M., O'Sullivan, R., Peters, A. H., Jenuwein, T., and Blasco, M. A. (2004) Epigenetic regulation of telomere length in mammalian cells by the Suv39hl and Suv39h2 histone methyltransferases. Nat. Genet. 36, 94-99.
    • (2004) Nat. Genet , vol.36 , pp. 94-99
    • Garcia-Cao, M.1    O'Sullivan, R.2    Peters, A.H.3    Jenuwein, T.4    Blasco, M.A.5
  • 59
    • 18644370262 scopus 로고    scopus 로고
    • Chromosomal instability in ulcerative colitis is related to telomere shortening
    • O'Sullivan, J. N., Bronner, M. P., Brentnall, T. A., et al. (2002) Chromosomal instability in ulcerative colitis is related to telomere shortening. Nat. Genet. 32, 280-284.
    • (2002) Nat. Genet , vol.32 , pp. 280-284
    • O'Sullivan, J.N.1    Bronner, M.P.2    Brentnall, T.A.3
  • 60
    • 0033593814 scopus 로고    scopus 로고
    • Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice
    • Hande, M. P., Samper, E., Lansdorp, P., and Blasco, M. A. (1999) Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice. J. Cell Biol. 144, 589-601.
    • (1999) J. Cell Biol , vol.144 , pp. 589-601
    • Hande, M.P.1    Samper, E.2    Lansdorp, P.3    Blasco, M.A.4
  • 61
    • 0036566036 scopus 로고    scopus 로고
    • Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres
    • Espejel, S., Franco, S., Rodriguez-Perales, S., Bouffler, S. D., Cigudosa, J.C., and Blasco, M. A. (2002) Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres. EMBO J. 21, 2207-2219.
    • (2002) EMBO J , vol.21 , pp. 2207-2219
    • Espejel, S.1    Franco, S.2    Rodriguez-Perales, S.3    Bouffler, S.D.4    Cigudosa, J.C.5    Blasco, M.A.6
  • 62
    • 84925548155 scopus 로고    scopus 로고
    • Telomere length measurement by fluorescence in situ hybridization and flow cytometry: Tips and pitfalls
    • Baerlocher, G. M., Mak, J., Tien, T., and Lansdorp, P. M. (2002) Telomere length measurement by fluorescence in situ hybridization and flow cytometry: tips and pitfalls. Cytometry 47, 89-99.
    • (2002) Cytometry , vol.47 , pp. 89-99
    • Baerlocher, G.M.1    Mak, J.2    Tien, T.3    Lansdorp, P.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.