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Volumn 15, Issue 10, 2007, Pages 1751-1766

Potential use of gene transfer in athletic performance enhancement

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANGIOGENIC PROTEIN; ANGIOPOIETIN 1; BLOOD CLOTTING FACTOR 9; BONE MORPHOGENETIC PROTEIN 2; FIBROBLAST GROWTH FACTOR; FOLLISTATIN; GLUTAMATE DECARBOXYLASE; GROWTH FACTOR; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; MITOCHONDRIAL PROTEIN; MUSCLE GROWTH FACTOR; MYOSTATIN; NAKED DNA; NARCOTIC ANALGESIC AGENT; ORNITHINE CARBAMOYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT SOMATOMEDIN C; RETROVIRUS VECTOR; SOMATOMEDIN C; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; VIRUS VECTOR;

EID: 34548723321     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/sj.mt.6300278     Document Type: Review
Times cited : (62)

References (141)
  • 2
    • 33646244749 scopus 로고    scopus 로고
    • Gene doping in sports: The science and ethics of genetically modified athletes
    • Schneider, AJ and Friedmann, T (2006). Gene doping in sports: The science and ethics of genetically modified athletes. Adv Genet 51: 1-110.
    • (2006) Adv Genet , vol.51 , pp. 1-110
    • Schneider, A.J.1    Friedmann, T.2
  • 4
    • 33947593811 scopus 로고    scopus 로고
    • Rethinking enhancement in sport
    • Miah, A (2006). Rethinking enhancement in sport. Ann NY Acad Sci 1093: 301-320.
    • (2006) Ann NY Acad Sci , vol.1093 , pp. 301-320
    • Miah, A.1
  • 5
    • 27744596872 scopus 로고    scopus 로고
    • Doping in the recombinant era: Strategies and counterstrategies
    • Azzazy, HM, Mansour, MM and Christenson, RH (2005). Doping in the recombinant era: Strategies and counterstrategies. Clin Biochem 38: 959-965.
    • (2005) Clin Biochem , vol.38 , pp. 959-965
    • Azzazy, H.M.1    Mansour, M.M.2    Christenson, R.H.3
  • 7
    • 33746228119 scopus 로고    scopus 로고
    • Knocking down disease with siRNAs
    • Dykxhoom, DM and Lieberman, J (2006). Knocking down disease with siRNAs. Cell 126: 231-235.
    • (2006) Cell , vol.126 , pp. 231-235
    • Dykxhoom, D.M.1    Lieberman, J.2
  • 8
    • 33750991861 scopus 로고    scopus 로고
    • The potential of oligonucleotides for therapeutic applications
    • Fichou, Y and Ferec, C (2006). The potential of oligonucleotides for therapeutic applications. Trends Biotechnol 24: 563-570.
    • (2006) Trends Biotechnol , vol.24 , pp. 563-570
    • Fichou, Y.1    Ferec, C.2
  • 9
    • 27744447551 scopus 로고    scopus 로고
    • Engineering zinc finger protein transcription factors: The therapeutic relevance of switching endogenous gene expression on or off at command
    • Gommans, WM, Haisma, HJ and Rots, MG (2005). Engineering zinc finger protein transcription factors: The therapeutic relevance of switching endogenous gene expression on or off at command. J Mol Biol 354 507-519.
    • (2005) J Mol Biol , vol.354 , pp. 507-519
    • Gommans, W.M.1    Haisma, H.J.2    Rots, M.G.3
  • 10
    • 18944373328 scopus 로고    scopus 로고
    • Highly efficient endogenous human gene correction using designed zinc-finger nucleases
    • Umov, FD, Miller, JC, Lee, YL, Beausejour, CM, Rock, JM, Augustus, S et al. (2005). Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435: 646-651.
    • (2005) Nature , vol.435 , pp. 646-651
    • Umov, F.D.1    Miller, J.C.2    Lee, Y.L.3    Beausejour, C.M.4    Rock, J.M.5    Augustus, S.6
  • 12
    • 3042651120 scopus 로고    scopus 로고
    • Electroporation for gene transfer to skeletal muscles: Current status
    • McMahon, JM and Wells, DJ (2004). Electroporation for gene transfer to skeletal muscles: Current status. BioDrugs 18: 155-165.
    • (2004) BioDrugs , vol.18 , pp. 155-165
    • McMahon, J.M.1    Wells, D.J.2
  • 13
    • 25144469504 scopus 로고    scopus 로고
    • Electric pulse-mediated gene delivery to various animal tissues
    • Mir, LM, Moller, PH, Andre, F and Gehl, J (2005). Electric pulse-mediated gene delivery to various animal tissues. Adv Genet 54: 83-114.
    • (2005) Adv Genet , vol.54 , pp. 83-114
    • Mir, L.M.1    Moller, P.H.2    Andre, F.3    Gehl, J.4
  • 14
    • 6444236227 scopus 로고    scopus 로고
    • Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmild DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia
    • Dal, Q, Huang, J, Klitzman, B, Dong, C, Goldschmidt-Clermont PJ, March, KL et al. (2004). Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmild DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. Circulation 110: 2457-2475.
    • (2004) Circulation , vol.110 , pp. 2457-2475
    • Dal, Q.1    Huang, J.2    Klitzman, B.3    Dong, C.4    Goldschmidt-Clermont, P.J.5    March, K.L.6
  • 15
    • 33745651801 scopus 로고    scopus 로고
    • An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia
    • Xie, D, Li Y, Reed, EA, Odronic, SI, Kontos, CD and Annex, BH (2006). An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia. J Vasc Surg 44: 166-175.
    • (2006) J Vasc Surg , vol.44 , pp. 166-175
    • Xie, D.1    Li, Y.2    Reed, E.A.3    Odronic, S.I.4    Kontos, C.D.5    Annex, B.H.6
  • 16
    • 33748702530 scopus 로고    scopus 로고
    • Correction at anemia in uremic rats by intramuscular injection of lentivirus carrying an erythropoietin gene
    • Oh, TK, Quan, GH, Kim, HY, Park, F and Kim, ST (2006). Correction at anemia in uremic rats by intramuscular injection of lentivirus carrying an erythropoietin gene. Am J Nephrol 26: 326-334.
    • (2006) Am J Nephrol , vol.26 , pp. 326-334
    • Oh, T.K.1    Quan, G.H.2    Kim, H.Y.3    Park, F.4    Kim, S.T.5
  • 17
    • 0035437193 scopus 로고    scopus 로고
    • Lentivirus administration to rat muscle provides efficient sustained expression of erythropoietin
    • Seppen, J, Barry, SC, Harder, B and Osborne, WR (2001). Lentivirus administration to rat muscle provides efficient sustained expression of erythropoietin. Blood 98: 594-596.
    • (2001) Blood , vol.98 , pp. 594-596
    • Seppen, J.1    Barry, S.C.2    Harder, B.3    Osborne, W.R.4
  • 18
    • 0033587741 scopus 로고    scopus 로고
    • Long-term regulated expression of growth hormone in mice after intramuscular gene transfer
    • Rivera, VM, Ye, X, Courage, NL, Sachar, J, Cerasoli F, Wilson, JM et al. (1999). Long-term regulated expression of growth hormone in mice after intramuscular gene transfer. Proc Natl Acad Sci USA 96 8657-8662.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8657-8662
    • Rivera, V.M.1    Ye, X.2    Courage, N.L.3    Sachar, J.4    Cerasoli, F.5    Wilson, J.M.6
  • 20
    • 33645456196 scopus 로고    scopus 로고
    • Increased transduction of skeletal muscle cells by fibroblast growth factor-modified adenoviral vectors
    • Menezes, KM, Mok, HS and Barry, MA (2006). Increased transduction of skeletal muscle cells by fibroblast growth factor-modified adenoviral vectors. Hum Gene Ther 17: 314-320.
    • (2006) Hum Gene Ther , vol.17 , pp. 314-320
    • Menezes, K.M.1    Mok, H.S.2    Barry, M.A.3
  • 21
    • 0033977047 scopus 로고    scopus 로고
    • Humoral immunity to adeno-associated virus type 2 vectors following administration to murine and nonhuman primate muscle
    • Chirmule, N, Xiao, W, Truneh, A, Schnell, MA, Hughes, JV, Zoltick, P et al. (2000). Humoral immunity to adeno-associated virus type 2 vectors following administration to murine and nonhuman primate muscle. J Virol 74: 2420-2425.
    • (2000) J Virol , vol.74 , pp. 2420-2425
    • Chirmule, N.1    Xiao, W.2    Truneh, A.3    Schnell, M.A.4    Hughes, J.V.5    Zoltick, P.6
  • 23
    • 0013442744 scopus 로고    scopus 로고
    • AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B
    • Manno, CS, Chew, AJ, Hutchison, S, Larson, PJ, Herzog, RW, Arruda, VR et al. (2003). AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B. Blood 101: 2963-2972.
    • (2003) Blood , vol.101 , pp. 2963-2972
    • Manno, C.S.1    Chew, A.J.2    Hutchison, S.3    Larson, P.J.4    Herzog, R.W.5    Arruda, V.R.6
  • 24
    • 3543025721 scopus 로고    scopus 로고
    • Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease
    • Morishita, R, Aoki, M, Hashiya, N, Makino, H, Yamasaki, K, Azuma, J et al. (2004). Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease. Hypertension 44: 203-209.
    • (2004) Hypertension , vol.44 , pp. 203-209
    • Morishita, R.1    Aoki, M.2    Hashiya, N.3    Makino, H.4    Yamasaki, K.5    Azuma, J.6
  • 26
    • 25144433013 scopus 로고    scopus 로고
    • Non-viral vectors for gene therapy: Clinical trials in cardiovascular disease
    • Shah, PB and Losordo, DW (2005). Non-viral vectors for gene therapy: clinical trials in cardiovascular disease. Adv Genet 54: 339-361.
    • (2005) Adv Genet , vol.54 , pp. 339-361
    • Shah, P.B.1    Losordo, D.W.2
  • 27
    • 0142023866 scopus 로고    scopus 로고
    • Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: A phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication
    • Rajagopalan, S, Mohler, ER, Lederman, RJ, Mendelsohn, FO, Saucedo, JF, Goldman, CK et al. (2003). Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: A phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circulation 108: 1933-1938.
    • (2003) Circulation , vol.108 , pp. 1933-1938
    • Rajagopalan, S.1    Mohler, E.R.2    Lederman, R.J.3    Mendelsohn, F.O.4    Saucedo, J.F.5    Goldman, C.K.6
  • 29
    • 4344715026 scopus 로고    scopus 로고
    • A facile nonviral method for delivering genes and siRNAs to skeletal muscle of mammalian limbs
    • Hagstrom, JE, Hegge, J, Zhang, G, Noble, M, Budker, V, Lewis, DL et al. (2004). A facile nonviral method for delivering genes and siRNAs to skeletal muscle of mammalian limbs. Mol Ther 10 386-398.
    • (2004) Mol Ther , vol.10 , pp. 386-398
    • Hagstrom, J.E.1    Hegge, J.2    Zhang, G.3    Noble, M.4    Budker, V.5    Lewis, D.L.6
  • 31
    • 28244481870 scopus 로고    scopus 로고
    • Gene transfer for hemophilia: Can therapeutic efficacy in large animals be safely translated to patients?
    • High, K (2005). Gene transfer for hemophilia: Can therapeutic efficacy in large animals be safely translated to patients? J Thromb Haemost 3: 1682-1691.
    • (2005) J Thromb Haemost , vol.3 , pp. 1682-1691
    • High, K.1
  • 32
    • 18244394301 scopus 로고    scopus 로고
    • Regional intravascular delivery of AAV-2-FIX to skeletal muscle achieves long-term correction of hemophilia B in a large animal model
    • Arruda, VR, Stedman, HH, Nichols, TC, Haskins, ME, Nicholson, M, Herzog, RW et al. (2005). Regional intravascular delivery of AAV-2-FIX to skeletal muscle achieves long-term correction of hemophilia B in a large animal model. Blood 105: 3458-3464.
    • (2005) Blood , vol.105 , pp. 3458-3464
    • Arruda, V.R.1    Stedman, H.H.2    Nichols, T.C.3    Haskins, M.E.4    Nicholson, M.5    Herzog, R.W.6
  • 33
    • 3042786281 scopus 로고    scopus 로고
    • Promoters and control elements: Designing expression cassettes for gene therapy
    • Papadakis, ED, Nicklin, SA, Baker, AH and White, SJ (2004). Promoters and control elements: Designing expression cassettes for gene therapy. Curr Gene Ther 4: 89-113.
    • (2004) Curr Gene Ther , vol.4 , pp. 89-113
    • Papadakis, E.D.1    Nicklin, S.A.2    Baker, A.H.3    White, S.J.4
  • 34
    • 14744301443 scopus 로고    scopus 로고
    • Controlling the kinetics of transgene expression by plasmid design
    • Yew, NS (2005). Controlling the kinetics of transgene expression by plasmid design. Adv Drug Deliv Rev 57: 769-780.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 769-780
    • Yew, N.S.1
  • 36
    • 33645734405 scopus 로고    scopus 로고
    • Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
    • Ott, MG, Schmidt M, Schwarzwaelder, K, Stein, S, Siler, U, Koehl, U et al. (2006). Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. Nat Med 12: 401-409.
    • (2006) Nat Med , vol.12 , pp. 401-409
    • Ott, M.G.1    Schmidt, M.2    Schwarzwaelder, K.3    Stein, S.4    Siler, U.5    Koehl, U.6
  • 37
    • 0142089747 scopus 로고    scopus 로고
    • Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
    • Raper, SE, Chirmule, N, Lee, FS, Wivel, NA, Bagg, A, Gao, GP et al. (2003). Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metob 80: 148-158.
    • (2003) Mol Genet Metob , vol.80 , pp. 148-158
    • Raper, S.E.1    Chirmule, N.2    Lee, F.S.3    Wivel, N.A.4    Bagg, A.5    Gao, G.P.6
  • 39
    • 33644820684 scopus 로고    scopus 로고
    • Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
    • Manna, CS, Pierce, GF, Arruda, VR, Glader, B, Ragni, M, Raska, JJ et al. (2006). Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. Nat Med 12: 342-347.
    • (2006) Nat Med , vol.12 , pp. 342-347
    • Manna, C.S.1    Pierce, G.F.2    Arruda, V.R.3    Glader, B.4    Ragni, M.5    Raska, J.J.6
  • 40
    • 32344438754 scopus 로고    scopus 로고
    • Directed evolution of adeno-associated virus yields enhanced gene delivery vectors
    • Maheshri, N, Koerber, JT, Kaspar, BK and Schaffer, DV (2006). Directed evolution of adeno-associated virus yields enhanced gene delivery vectors. Nat Biotechnol 24: 198-204.
    • (2006) Nat Biotechnol , vol.24 , pp. 198-204
    • Maheshri, N.1    Koerber, J.T.2    Kaspar, B.K.3    Schaffer, D.V.4
  • 41
    • 28844452008 scopus 로고    scopus 로고
    • Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates
    • Gao, G, Lu, Y, Calcedo, R, Grant RL, Bell, P, Wang, L et al. (2006). Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates. Mol Ther 13: 77-87.
    • (2006) Mol Ther , vol.13 , pp. 77-87
    • Gao, G.1    Lu, Y.2    Calcedo, R.3    Grant, R.L.4    Bell, P.5    Wang, L.6
  • 42
    • 28844483864 scopus 로고    scopus 로고
    • High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses
    • De, BP, Heguy, A, Hackett, NR, Ferris, B, Leopold, PL, Lee, J et al. (2006). High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses. Mol Ther 13: 67-76.
    • (2006) Mol Ther , vol.13 , pp. 67-76
    • De, B.P.1    Heguy, A.2    Hackett, N.R.3    Ferris, B.4    Leopold, P.L.5    Lee, J.6
  • 44
    • 1942457251 scopus 로고    scopus 로고
    • Erythropoietin gene therapy leads to autoimmune anemia in macaques
    • Gao, G, Lebherz, C, Weiner, DJ, Grant R, Calcedo, R, McCullough, B et al. (2004). Erythropoietin gene therapy leads to autoimmune anemia in macaques. Blood 103: 3300-3302.
    • (2004) Blood , vol.103 , pp. 3300-3302
    • Gao, G.1    Lebherz, C.2    Weiner, D.J.3    Grant, R.4    Calcedo, R.5    McCullough, B.6
  • 46
    • 34047234725 scopus 로고    scopus 로고
    • Erythropoietin involves the phosphatidylinositol 3-kinase pathway, 14-3-3 protein and FOXO3a nuclear trafficking to preserve endothelial cell integrity
    • Chong, ZZ and Maiese, K (2007). Erythropoietin involves the phosphatidylinositol 3-kinase pathway, 14-3-3 protein and FOXO3a nuclear trafficking to preserve endothelial cell integrity. Br J Pharmacol 150: 839-850.
    • (2007) Br J Pharmacol , vol.150 , pp. 839-850
    • Chong, Z.Z.1    Maiese, K.2
  • 47
    • 20044392832 scopus 로고    scopus 로고
    • Gene electro-transfer of an improved erythropoietin plasmid in mice and non-human primates
    • Fattori, E, Cappelletti, M, Zampaglione, I, Mennuni, C, Calvaruso, F, Arcuri, M et al. (2005). Gene electro-transfer of an improved erythropoietin plasmid in mice and non-human primates. J Gene Med 7: 228-236.
    • (2005) J Gene Med , vol.7 , pp. 228-236
    • Fattori, E.1    Cappelletti, M.2    Zampaglione, I.3    Mennuni, C.4    Calvaruso, F.5    Arcuri, M.6
  • 48
    • 12744261398 scopus 로고    scopus 로고
    • Inducible production of erythropoietin using intramuscular injection of block copolymer/DNA formulation
    • Richard, P, Pollard, H, Lanctin, C, Bello-Roufaï, M, Désigaux, L, Escande, D et al. (2005). Inducible production of erythropoietin using intramuscular injection of block copolymer/DNA formulation. J Gene Med 7: 80-86.
    • (2005) J Gene Med , vol.7 , pp. 80-86
    • Richard, P.1    Pollard, H.2    Lanctin, C.3    Bello-Roufaï, M.4    Désigaux, L.5    Escande, D.6
  • 49
    • 34249863632 scopus 로고    scopus 로고
    • Sensitive and precise regulation of haemoglobin after gene transfer of erythropoietin to muscle tissue using electroporation
    • Hojman, P, Gissel, H and Gehl, J (2007). Sensitive and precise regulation of haemoglobin after gene transfer of erythropoietin to muscle tissue using electroporation. Gene Ther 14: 950-959.
    • (2007) Gene Ther , vol.14 , pp. 950-959
    • Hojman, P.1    Gissel, H.2    Gehl, J.3
  • 50
    • 13544262341 scopus 로고    scopus 로고
    • Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer
    • Rivera, VM, Gao, GP, Grant RL, Schnell, MA, Zoltick, PW, Rozamus, LW et al. (2005). Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer. Blood 105: 1424-1430.
    • (2005) Blood , vol.105 , pp. 1424-1430
    • Rivera, V.M.1    Gao, G.P.2    Grant, R.L.3    Schnell, M.A.4    Zoltick, P.W.5    Rozamus, L.W.6
  • 51
    • 1142275288 scopus 로고    scopus 로고
    • Lentivectors for regulated and reversible cutaneous gene delivery
    • Siprashvill, Z and Khavari, PA (2004). Lentivectors for regulated and reversible cutaneous gene delivery. Mol Ther 9: 93-100.
    • (2004) Mol Ther , vol.9 , pp. 93-100
    • Siprashvill, Z.1    Khavari, P.A.2
  • 52
    • 33750611942 scopus 로고    scopus 로고
    • Adipose tissue as a novel target for in vivo gene transfer by adeno-associated viral vectors
    • Mizukami, H, Mimuro, J, Ogura, T, Okada, T, Urabe, M, Kume, A et al. (2006). Adipose tissue as a novel target for in vivo gene transfer by adeno-associated viral vectors. Hum Gene Ther 17 921-928.
    • (2006) Hum Gene Ther , vol.17 , pp. 921-928
    • Mizukami, H.1    Mimuro, J.2    Ogura, T.3    Okada, T.4    Urabe, M.5    Kume, A.6
  • 53
    • 29944446086 scopus 로고    scopus 로고
    • Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands
    • Wang, J, Voutetakis, A, Papa, M, Rivera, VM, Clackson, T, Lodde, BM et al. (2006). Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands. Gene Ther 13: 187-190.
    • (2006) Gene Ther , vol.13 , pp. 187-190
    • Wang, J.1    Voutetakis, A.2    Papa, M.3    Rivera, V.M.4    Clackson, T.5    Lodde, B.M.6
  • 54
    • 0037258964 scopus 로고    scopus 로고
    • Drugs for increasing oxygen and their potential use in doping: A review
    • Gaudard, A, Varlet-Marle, E, Bressolle, F and Audran, M (2003). Drugs for increasing oxygen and their potential use in doping: A review. Sports Med 33: 187-212.
    • (2003) Sports Med , vol.33 , pp. 187-212
    • Gaudard, A.1    Varlet-Marle, E.2    Bressolle, F.3    Audran, M.4
  • 56
    • 22644433564 scopus 로고    scopus 로고
    • Long-term expression of erythropoietin from myoblasts immobilized in biocompatible and neavascularized microcapsules
    • Orive, G, De Castro, M, Ponce, S, Hernández, RM, Gascón, AR, Bosch, M et al. (2005). Long-term expression of erythropoietin from myoblasts immobilized in biocompatible and neavascularized microcapsules. Mol Ther 12: 283-289.
    • (2005) Mol Ther , vol.12 , pp. 283-289
    • Orive, G.1    De Castro, M.2    Ponce, S.3    Hernández, R.M.4    Gascón, A.R.5    Bosch, M.6
  • 57
  • 58
    • 33646903235 scopus 로고    scopus 로고
    • Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure
    • Eliopoulos, N, Gagnon, RF, Francois, M and Galipeau, J (2006) Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure. J Am Soc Nephrol 17: 1676-1584.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1676-1584
    • Eliopoulos, N.1    Gagnon, R.F.2    Francois, M.3    Galipeau, J.4
  • 59
    • 0013447778 scopus 로고    scopus 로고
    • Recombinant DNA advisory committee, September 25-26, U.S. Department of Health and Human Services. National Institutes of Health, Accessed April
    • Recombinant DNA advisory committee. Minutes of meeting, September 25-26, 2000. U.S. Department of Health and Human Services. National Institutes of Health . Accessed April 2007.
    • (2000) Minutes of meeting
  • 60
    • 0034266617 scopus 로고    scopus 로고
    • Ligand-dependent regulation of vascular endothelial growth factor and erythropoietin expression by a plasmid-based autoinducible GeneSwitch system
    • Abruzzese, RV, Godin, D, Mehta, V, Perrard, JL, French, M, Nelson, W et al. (2000). Ligand-dependent regulation of vascular endothelial growth factor and erythropoietin expression by a plasmid-based autoinducible GeneSwitch system. Mol Ther 2: 276-287.
    • (2000) Mol Ther , vol.2 , pp. 276-287
    • Abruzzese, R.V.1    Godin, D.2    Mehta, V.3    Perrard, J.L.4    French, M.5    Nelson, W.6
  • 61
    • 0036785428 scopus 로고    scopus 로고
    • Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy
    • Binley, K, Askham, Z, Iqball, S, Spearman, H, Martin, L, de Alwis, M et al. (2002). Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy. Blood 100: 2406-2413.
    • (2002) Blood , vol.100 , pp. 2406-2413
    • Binley, K.1    Askham, Z.2    Iqball, S.3    Spearman, H.4    Martin, L.5    de Alwis, M.6
  • 62
    • 0037089336 scopus 로고    scopus 로고
    • A novel mutation in the erythropoietin receptor gene is associated with familial erythrocytosis
    • Arcasoy, MO, Karayal, AF, Segal, HM, Sinning, JG and Forget, BG (2002). A novel mutation in the erythropoietin receptor gene is associated with familial erythrocytosis. Blood 99: 3066-3069.
    • (2002) Blood , vol.99 , pp. 3066-3069
    • Arcasoy, M.O.1    Karayal, A.F.2    Segal, H.M.3    Sinning, J.G.4    Forget, B.G.5
  • 63
    • 0027215519 scopus 로고
    • Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis
    • de la Chapelle, A, Traskelin, AL and Juvonen, E (1993). Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc Natl Acad Sci US4 90: 4495-4499.
    • (1993) Proc Natl Acad Sci , vol.US4 , Issue.90 , pp. 4495-4499
    • de la Chapelle, A.1    Traskelin, A.L.2    Juvonen, E.3
  • 64
    • 33745926802 scopus 로고    scopus 로고
    • VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis
    • Tam, BY, Wei, K, Rudge, JS, Hoffman, J, Holash, J, Park, SK et al. (2006). VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nat Med 12: 793-800.
    • (2006) Nat Med , vol.12 , pp. 793-800
    • Tam, B.Y.1    Wei, K.2    Rudge, J.S.3    Hoffman, J.4    Holash, J.5    Park, S.K.6
  • 65
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • Lin, J, Handschin, C and Spiegelman, BM (2005). Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 1: 361-370.
    • (2005) Cell Metab , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 67
    • 0037102256 scopus 로고    scopus 로고
    • Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres
    • Lin, J, Wu, H, Tarr, PT, Zhang, CY, Wu, Z, Boss, O et al. (2002). Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature 418: 797-801.
    • (2002) Nature , vol.418 , pp. 797-801
    • Lin, J.1    Wu, H.2    Tarr, P.T.3    Zhang, C.Y.4    Wu, Z.5    Boss, O.6
  • 68
    • 21144446106 scopus 로고    scopus 로고
    • PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis
    • Leone, TC, Lehman, JJ, Finck, BN, Schaeffer, PJ, Wende AR, Boudina, S et al. (2005). PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol 3: E101.
    • (2005) PLoS Biol , vol.3
    • Leone, T.C.1    Lehman, J.J.2    Finck, B.N.3    Schaeffer, P.J.4    Wende, A.R.5    Boudina, S.6
  • 69
    • 33845674997 scopus 로고    scopus 로고
    • The transcriptional coactivator PGC-1 beta drives the formation of oxidative type IIX fibers in skeletal muscle
    • Arany, Z, Lebrasseur, N, Morris, C, Smith, E, Yang, W, Ma, Y et al. (2007). The transcriptional coactivator PGC-1 beta drives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab 5: 35-46.
    • (2007) Cell Metab , vol.5 , pp. 35-46
    • Arany, Z.1    Lebrasseur, N.2    Morris, C.3    Smith, E.4    Yang, W.5    Ma, Y.6
  • 70
    • 0142091356 scopus 로고    scopus 로고
    • PPARgamma coactivator 1β/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity
    • Kamei, Y, Ohizumi, H, Fujitani, Y, Nemoto, T, Tanaka, T, Takahashi, N et al. (2003). PPARgamma coactivator 1β/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity. Proc Natl Acad Sci USA 100: 12378-12383.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12378-12383
    • Kamei, Y.1    Ohizumi, H.2    Fujitani, Y.3    Nemoto, T.4    Tanaka, T.5    Takahashi, N.6
  • 71
    • 23644433329 scopus 로고    scopus 로고
    • The mitochondrial genome in human adaptive radiation and disease: On the road to therapeutics and performance enhancement
    • Wallace, DC (2005). The mitochondrial genome in human adaptive radiation and disease: On the road to therapeutics and performance enhancement. Gene 354: 169-180.
    • (2005) Gene , vol.354 , pp. 169-180
    • Wallace, D.C.1
  • 72
    • 24644445081 scopus 로고    scopus 로고
    • NOGA-guided analysis of regional myocardial perfusion abnormalities treated with intramyocardial injections of plasmid encoding vascular endothelial growth factor A-165 in patients with chronic myocardial ischemia: Subanalysis of the EUROINJECT-ONE multicenter double-blind randomized study
    • Gyongyosi, M, Khorsand, A, Zamini, S, Sperker, W, Strehblow, C, Kastrup, J et al. (2005). NOGA-guided analysis of regional myocardial perfusion abnormalities treated with intramyocardial injections of plasmid encoding vascular endothelial growth factor A-165 in patients with chronic myocardial ischemia: Subanalysis of the EUROINJECT-ONE multicenter double-blind randomized study. Circulation 112: 1157-1165.
    • (2005) Circulation , vol.112 , pp. 1157-1165
    • Gyongyosi, M.1    Khorsand, A.2    Zamini, S.3    Sperker, W.4    Strehblow, C.5    Kastrup, J.6
  • 73
    • 33745643590 scopus 로고    scopus 로고
    • Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: A double-blind randomized trial
    • Kusumanto, YH, van Weel, V, Mulder, NH, Smit, AJ, van den Dungen, JJ, Hooymans, JM et al. (2006). Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: A double-blind randomized trial. Hum Gene Ther 17: 683-691.
    • (2006) Hum Gene Ther , vol.17 , pp. 683-691
    • Kusumanto, Y.H.1    van Weel, V.2    Mulder, N.H.3    Smit, A.J.4    van den Dungen, J.J.5    Hooymans, J.M.6
  • 74
    • 34548740891 scopus 로고    scopus 로고
    • ClinicalTrials.gov - A Service of the U.S. National Institutes of Health (2007). EW-A-401 to treat intermittent Claudication. . Accessed May 2007.
    • ClinicalTrials.gov - A Service of the U.S. National Institutes of Health (2007). EW-A-401 to treat intermittent Claudication. . Accessed May 2007.
  • 75
    • 34548738387 scopus 로고    scopus 로고
    • Gene Therapy Clinical Trials World Wide (2007). The Journal of Gene Medicine Clinical Trial site. WILEY . Accessed May 2007.
    • Gene Therapy Clinical Trials World Wide (2007). The Journal of Gene Medicine Clinical Trial site. WILEY . Accessed May 2007.
  • 76
    • 12144289916 scopus 로고    scopus 로고
    • Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: Its role in ischemia
    • Ho, HK, Jang, JJ, Kaji, S, Spektor, G, Fong, A, Yang, P et al. (2004). Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: Its role in ischemia. Circulation 109: 1314-1319.
    • (2004) Circulation , vol.109 , pp. 1314-1319
    • Ho, H.K.1    Jang, J.J.2    Kaji, S.3    Spektor, G.4    Fong, A.5    Yang, P.6
  • 77
    • 5444253160 scopus 로고    scopus 로고
    • Design of the Del-1 for therapeutic angiogenesis trial (DELTA-1), a phase II multicenter, double-blind, placebo-controlled trial of VLTS-589 in subjects with intermittent claudication secondary to peripheral arterial disease
    • Rajagopalan, S, Olin, JW, Young, S, Erikson, M, Grossman, PM, Mendelsohn, FO et al. (2004). Design of the Del-1 for therapeutic angiogenesis trial (DELTA-1), a phase II multicenter, double-blind, placebo-controlled trial of VLTS-589 in subjects with intermittent claudication secondary to peripheral arterial disease. Hum Gene Ther 15: 619-624.
    • (2004) Hum Gene Ther , vol.15 , pp. 619-624
    • Rajagopalan, S.1    Olin, J.W.2    Young, S.3    Erikson, M.4    Grossman, P.M.5    Mendelsohn, F.O.6
  • 78
    • 0035136062 scopus 로고    scopus 로고
    • Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle
    • Musaro, A, McCullagh, K, Paul, A, Houghton, L, Dobrowolny, G, Molinaro, M et al. (2001). Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat Genet 27: 195-200.
    • (2001) Nat Genet , vol.27 , pp. 195-200
    • Musaro, A.1    McCullagh, K.2    Paul, A.3    Houghton, L.4    Dobrowolny, G.5    Molinaro, M.6
  • 79
    • 0032416479 scopus 로고    scopus 로고
    • Viral mediated expression of insulin-like growth factor 1 blocks the aging-related loss of skeletal muscle function
    • Barton-Davis, ER, Shoturma, DI, Musaro, A, Rosenthal, N and Sweeney, HL (1998). Viral mediated expression of insulin-like growth factor 1 blocks the aging-related loss of skeletal muscle function. Proc Natl Acad Sci USA 95: 15603-15607.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15603-15607
    • Barton-Davis, E.R.1    Shoturma, D.I.2    Musaro, A.3    Rosenthal, N.4    Sweeney, H.L.5
  • 80
    • 1342325478 scopus 로고    scopus 로고
    • Viral expression of insulin-like growth factor-1 enhances muscle hypertrophy in resistance-trained rats
    • Lee, S, Barton, ER, Sweeney, HL and Farrar, RP (2004). Viral expression of insulin-like growth factor-1 enhances muscle hypertrophy in resistance-trained rats. J Appl Physiol 96: 1097-1104.
    • (2004) J Appl Physiol , vol.96 , pp. 1097-1104
    • Lee, S.1    Barton, E.R.2    Sweeney, H.L.3    Farrar, R.P.4
  • 81
    • 0038066430 scopus 로고    scopus 로고
    • IGF-1 gene transfer by electroporation promotes regeneration in a muscle injury model
    • Takahashi, T, Ishida, K, Itoh, K, Konishi, Y, Yagyu, KI, Tominaga, A et al. (2003). IGF-1 gene transfer by electroporation promotes regeneration in a muscle injury model. Gene Ther 10: 612-620.
    • (2003) Gene Ther , vol.10 , pp. 612-620
    • Takahashi, T.1    Ishida, K.2    Itoh, K.3    Konishi, Y.4    Yagyu, K.I.5    Tominaga, A.6
  • 82
    • 24044511547 scopus 로고    scopus 로고
    • Mechanical signals, IGF-I gene splicing and muscle adaptation
    • Goldspink, G (2005). Mechanical signals, IGF-I gene splicing and muscle adaptation. Physiology (Bethesda) 20: 232-238.
    • (2005) Physiology (Bethesda) , vol.20 , pp. 232-238
    • Goldspink, G.1
  • 83
    • 24344452642 scopus 로고    scopus 로고
    • Improved muscle healing through enhanced regeneration and reduced fibrosis in myostatin-null mice
    • McCroskery, S, Thomas, M, Platt, L, Hennebry, A, Nishimura, T, McLeay, L et al. (2005). Improved muscle healing through enhanced regeneration and reduced fibrosis in myostatin-null mice. J Cell Sci 118: 3531-3541.
    • (2005) J Cell Sci , vol.118 , pp. 3531-3541
    • McCroskery, S.1    Thomas, M.2    Platt, L.3    Hennebry, A.4    Nishimura, T.5    McLeay, L.6
  • 84
    • 27544453428 scopus 로고    scopus 로고
    • Muscle regeneration through myostatin inhibition
    • Wagner, KR (2005). Muscle regeneration through myostatin inhibition. Curr Opin Rheumatol 17: 720-724.
    • (2005) Curr Opin Rheumatol , vol.17 , pp. 720-724
    • Wagner, K.R.1
  • 85
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • Lee, SJ (2004). Regulation of muscle mass by myostatin. Annul Rev Cell Dev Biol 20: 61-86.
    • (2004) Annul Rev Cell Dev Biol , vol.20 , pp. 61-86
    • Lee, S.J.1
  • 86
    • 33645822277 scopus 로고    scopus 로고
    • Transcriptional profiling of myostatin-knockout mice implicates Wnt signaling in postnatal skeletal muscle growth and hypertrophy
    • Steelman, CA, Recknor, JC, Nettleton, D and Reecy, JM (2006). Transcriptional profiling of myostatin-knockout mice implicates Wnt signaling in postnatal skeletal muscle growth and hypertrophy. FASEB J 20: 580-582.
    • (2006) FASEB J , vol.20 , pp. 580-582
    • Steelman, C.A.1    Recknor, J.C.2    Nettleton, D.3    Reecy, J.M.4
  • 87
    • 33644853928 scopus 로고    scopus 로고
    • Postnatal expression of myostatin propeptide cDNA maintained high muscle growth and normal adipose tissue mass in transgenic mice fed a high-fat diet
    • Yang, J and Zhao, B (2006). Postnatal expression of myostatin propeptide cDNA maintained high muscle growth and normal adipose tissue mass in transgenic mice fed a high-fat diet. Mol Reprod Dev 73: 462-469.
    • (2006) Mol Reprod Dev , vol.73 , pp. 462-469
    • Yang, J.1    Zhao, B.2
  • 88
    • 33745577150 scopus 로고    scopus 로고
    • A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep
    • Clop, A, Marcq, F, Takeda, H, Pirottin, D, Tordoir, X, Bibé, B et al. (2006). A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nat Genet 38: 813-818.
    • (2006) Nat Genet , vol.38 , pp. 813-818
    • Clop, A.1    Marcq, F.2    Takeda, H.3    Pirottin, D.4    Tordoir, X.5    Bibé, B.6
  • 89
    • 33847413126 scopus 로고    scopus 로고
    • Effect of maternal myostatin antibody on offspring growth performance and body composition in mice
    • Liang, YC, Yeh, JY and Ou, BR (2007). Effect of maternal myostatin antibody on offspring growth performance and body composition in mice. J Exp Biol 210: 477-483.
    • (2007) J Exp Biol , vol.210 , pp. 477-483
    • Liang, Y.C.1    Yeh, J.Y.2    Ou, B.R.3
  • 92
    • 0035979253 scopus 로고    scopus 로고
    • Regulation of myostatin activity and muscle growth
    • Lee, SJ and McPherron, AC (2001). Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci USA 98: 9306-9311.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9306-9311
    • Lee, S.J.1    McPherron, A.C.2
  • 93
    • 33646672441 scopus 로고    scopus 로고
    • Expression of the TGF-beta family of ligands is developmentally regulated in skeletal muscle of neonatal rats
    • Suryawan, A, Frank, JW, Nguyen, HV and Davis, TA (2006). Expression of the TGF-beta family of ligands is developmentally regulated in skeletal muscle of neonatal rats. Pediatr Res 59: 175-179.
    • (2006) Pediatr Res , vol.59 , pp. 175-179
    • Suryawan, A.1    Frank, J.W.2    Nguyen, H.V.3    Davis, T.A.4
  • 94
    • 2342627231 scopus 로고    scopus 로고
    • Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin
    • Iezzi, S, Di Padova, M, Serra, C, Caretti, G, Simone, C, Maklan, E et al. (2004). Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin. Dev Cell 6: 673-684.
    • (2004) Dev Cell , vol.6 , pp. 673-684
    • Iezzi, S.1    Di Padova, M.2    Serra, C.3    Caretti, G.4    Simone, C.5    Maklan, E.6
  • 95
    • 0028918915 scopus 로고
    • Multiple defects and perinatal death in mice deficient in follistatin
    • Matzuk, MM, Lu, N, Vogel, H, Sellheyer, K, Roop, DR and Bradley, A (1995). Multiple defects and perinatal death in mice deficient in follistatin. Nature 374: 360-363.
    • (1995) Nature , vol.374 , pp. 360-363
    • Matzuk, M.M.1    Lu, N.2    Vogel, H.3    Sellheyer, K.4    Roop, D.R.5    Bradley, A.6
  • 96
    • 2342515391 scopus 로고    scopus 로고
    • Follistatin complexes myostatin and antagonises myostatin-mediated inhibition of myogenesis
    • Amthor, H, Nicholas, G, McKinnell, I, Kemp, CF, Sharma, M, Kambadur, R et al. (2004). Follistatin complexes myostatin and antagonises myostatin-mediated inhibition of myogenesis. Dev Biol 270: 19-30.
    • (2004) Dev Biol , vol.270 , pp. 19-30
    • Amthor, H.1    Nicholas, G.2    McKinnell, I.3    Kemp, C.F.4    Sharma, M.5    Kambadur, R.6
  • 97
    • 0033992002 scopus 로고    scopus 로고
    • The induction of skeletal muscle hypertrophy by a ski transgene is promoter-dependent
    • Sutrave, P, Leferovich, JM, Kelly, AM and Hughes, SH (2000). The induction of skeletal muscle hypertrophy by a ski transgene is promoter-dependent. Gene 241: 107-116.
    • (2000) Gene , vol.241 , pp. 107-116
    • Sutrave, P.1    Leferovich, J.M.2    Kelly, A.M.3    Hughes, S.H.4
  • 99
    • 34247166670 scopus 로고    scopus 로고
    • AAV-mediated delivery of a mutated myostatin propeptide ameliorates calpain 3 but not α-sarcoglycan deficiency
    • Bartoli, M, Poupiot, J, Vulin, A, Fougerousse, F, Arandel, L, Danielle, N et al. (2007). AAV-mediated delivery of a mutated myostatin propeptide ameliorates calpain 3 but not α-sarcoglycan deficiency. Gene Ther 14: 733-740.
    • (2007) Gene Ther , vol.14 , pp. 733-740
    • Bartoli, M.1    Poupiot, J.2    Vulin, A.3    Fougerousse, F.4    Arandel, L.5    Danielle, N.6
  • 100
    • 24944552084 scopus 로고    scopus 로고
    • Myostatin gene silenced by RNAi show a zebrafish giant phenotype
    • Acosta, J, Carpio, Y, Borroto, I, Gonzalez, O and Estrada, MP (2005). Myostatin gene silenced by RNAi show a zebrafish giant phenotype. J Biotechnol 119: 324-331.
    • (2005) J Biotechnol , vol.119 , pp. 324-331
    • Acosta, J.1    Carpio, Y.2    Borroto, I.3    Gonzalez, O.4    Estrada, M.P.5
  • 101
    • 4344649468 scopus 로고    scopus 로고
    • Effects of an alleged myostatin-binding supplement and heavy resistance training on serum myostatin, muscle strength and mass and body composition
    • Willoughby, DS (2004). Effects of an alleged myostatin-binding supplement and heavy resistance training on serum myostatin, muscle strength and mass and body composition. Int J Sport Nutr Exerc Metab 14: 461-472.
    • (2004) Int J Sport Nutr Exerc Metab , vol.14 , pp. 461-472
    • Willoughby, D.S.1
  • 102
    • 1842610095 scopus 로고    scopus 로고
    • Effects of heavy resistance training on myostatin mRNA and protein expression
    • Willoughby, DS (2004). Effects of heavy resistance training on myostatin mRNA and protein expression. Med Sci Sports Exerc 36: 574-582.
    • (2004) Med Sci Sports Exerc , vol.36 , pp. 574-582
    • Willoughby, D.S.1
  • 104
    • 0038505243 scopus 로고    scopus 로고
    • Myostatin gene expression is reduced in humans with heavy-resistance strength training: A brief communication
    • Roth, SM, Martel, GF, Ferrell, RE, Metter, EJ, Hurley, BF and Rogers, MA (2003). Myostatin gene expression is reduced in humans with heavy-resistance strength training: A brief communication. Exp Biol Med (Maywood) 228: 706-709.
    • (2003) Exp Biol Med (Maywood) , vol.228 , pp. 706-709
    • Roth, S.M.1    Martel, G.F.2    Ferrell, R.E.3    Metter, E.J.4    Hurley, B.F.5    Rogers, M.A.6
  • 105
    • 33846236830 scopus 로고    scopus 로고
    • Suppression of testosterone does not blunt mRNA expression of myoD, myogenin, IGF, myostatin or androgen receptor post strength training in humans
    • Kvorning, T, Andersen M, Brixen K, Schjerling P, Suetta, C and Madsen, K (2007). Suppression of testosterone does not blunt mRNA expression of myoD, myogenin, IGF, myostatin or androgen receptor post strength training in humans. J Physiol 578: 579-593.
    • (2007) J Physiol , vol.578 , pp. 579-593
    • Kvorning, T.1    Andersen, M.2    Brixen, K.3    Schjerling, P.4    Suetta, C.5    Madsen, K.6
  • 107
    • 0036784164 scopus 로고    scopus 로고
    • Aging-related satellite cell differentiation defect occurs prematurely after Ski-induced muscle hypertrophy
    • Charge, SB, Brack AS and Hughes, SM (2002). Aging-related satellite cell differentiation defect occurs prematurely after Ski-induced muscle hypertrophy. Am J Physiol Cell Physiol 283: C1228-1241.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Charge, S.B.1    Brack, A.S.2    Hughes, S.M.3
  • 108
    • 31144444526 scopus 로고    scopus 로고
    • Growth hormone isoforms and segments/fragments: Molecular structure and laboratory measurement
    • De Palo, EF, De Filippis, V, Gatti, R and Spinella, P (2006). Growth hormone isoforms and segments/fragments: Molecular structure and laboratory measurement. Clin Chim Acta 364: 67-76.
    • (2006) Clin Chim Acta , vol.364 , pp. 67-76
    • De Palo, E.F.1    De Filippis, V.2    Gatti, R.3    Spinella, P.4
  • 110
    • 34250197567 scopus 로고    scopus 로고
    • Increased serum concentration of IGFBP-4 and IGFBP-5 in healthy adults during one month's treatment with supraphysiological doses of growth hormone
    • Ehmborg, C, Ohlsson, C, Mohan, S, Bengtsson, BK and Rosen, T (2007). Increased serum concentration of IGFBP-4 and IGFBP-5 in healthy adults during one month's treatment with supraphysiological doses of growth hormone. Growth Horm IGF Res 17: 234-241.
    • (2007) Growth Horm IGF Res , vol.17 , pp. 234-241
    • Ehmborg, C.1    Ohlsson, C.2    Mohan, S.3    Bengtsson, B.K.4    Rosen, T.5
  • 111
    • 0034855540 scopus 로고    scopus 로고
    • Glucocorticoid-regulated expression of exogenous human growth hormone gene in rats
    • Inazawa, T, Tanabe, T, Yamada, H, Nakaoka, T, Hashimoto, Y, Yamasaki, T et al. (2001). Glucocorticoid-regulated expression of exogenous human growth hormone gene in rats. Mol Ther 4: 267-272.
    • (2001) Mol Ther , vol.4 , pp. 267-272
    • Inazawa, T.1    Tanabe, T.2    Yamada, H.3    Nakaoka, T.4    Hashimoto, Y.5    Yamasaki, T.6
  • 112
    • 33845915283 scopus 로고    scopus 로고
    • Peroni, CN, Cecchi, CR, Damiani, R, Soares, CR, Ribela, MT, do Rocio Arkaten, R et al. (2006). High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes: Prospects for an animal model of cutaneous gene therapy. Mol Biotechnol 34: 239-245.
    • Peroni, CN, Cecchi, CR, Damiani, R, Soares, CR, Ribela, MT, do Rocio Arkaten, R et al. (2006). High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes: Prospects for an animal model of cutaneous gene therapy. Mol Biotechnol 34: 239-245.
  • 113
    • 0038715419 scopus 로고    scopus 로고
    • Skeletal muscle as an artificial endocrine tissue
    • Goldspink G (2003). Skeletal muscle as an artificial endocrine tissue. Best Pract Res Clin Endocrinol Metab 17: 211-222.
    • (2003) Best Pract Res Clin Endocrinol Metab , vol.17 , pp. 211-222
    • Goldspink, G.1
  • 114
    • 23344437329 scopus 로고    scopus 로고
    • Plasmid-based growth hormone-releasing hormone supplementation and its applications
    • Khan, AS, Brown, PA and Draghia-Akli, R (2005). Plasmid-based growth hormone-releasing hormone supplementation and its applications. Curr Opin Mol Ther 7: 306-316.
    • (2005) Curr Opin Mol Ther , vol.7 , pp. 306-316
    • Khan, A.S.1    Brown, P.A.2    Draghia-Akli, R.3
  • 115
    • 10844221772 scopus 로고    scopus 로고
    • Growth hormone releasing hormone plasmid supplementation, a potential treatment for cancer cachexia, does not increase tumor growth in nude mice
    • Khan, AS, Smith, LC, Anscombe, IW, Cummings, KK, Pope, MA, Draghla-Akli, R et al. (2005). Growth hormone releasing hormone plasmid supplementation, a potential treatment for cancer cachexia, does not increase tumor growth in nude mice. Cancer Gene Ther 12: 54-60.
    • (2005) Cancer Gene Ther , vol.12 , pp. 54-60
    • Khan, A.S.1    Smith, L.C.2    Anscombe, I.W.3    Cummings, K.K.4    Pope, M.A.5    Draghla-Akli, R.6
  • 117
    • 26944454879 scopus 로고    scopus 로고
    • The potential of gene therapy for fracture healing in osteoporosis
    • Egermann, M, Schneider, E, Evans, CH and Baltzer, AW (2005). The potential of gene therapy for fracture healing in osteoporosis. Osteoporos Int 16 (suppl. 2): S120-S128.
    • (2005) Osteoporos Int , vol.16 , Issue.SUPPL. 2
    • Egermann, M.1    Schneider, E.2    Evans, C.H.3    Baltzer, A.W.4
  • 118
    • 13744256148 scopus 로고    scopus 로고
    • Delivery of growth factors using gene therapy to enhance bone healing
    • Southwood, LL, Frisble, DD, Kawcak, CE and McIlwraith, CW (2004). Delivery of growth factors using gene therapy to enhance bone healing. Vet Surg 33: 565-578.
    • (2004) Vet Surg , vol.33 , pp. 565-578
    • Southwood, L.L.1    Frisble, D.D.2    Kawcak, C.E.3    McIlwraith, C.W.4
  • 119
    • 33646946177 scopus 로고    scopus 로고
    • Direct adenoviral transfer of bone morphogenetic protein-2 cDNA enhances fracture healing in osteoporotic sheep
    • Egermann, M, Baltzer, AW, Adamaszek, S, Evans, C, Robbins, P, Schneider, E et al. (2006). Direct adenoviral transfer of bone morphogenetic protein-2 cDNA enhances fracture healing in osteoporotic sheep. Hum Gene Ther 17: 507-517.
    • (2006) Hum Gene Ther , vol.17 , pp. 507-517
    • Egermann, M.1    Baltzer, A.W.2    Adamaszek, S.3    Evans, C.4    Robbins, P.5    Schneider, E.6
  • 121
    • 0036665006 scopus 로고    scopus 로고
    • Gene transfer approaches to the healing of bone and cartilage
    • Lieberman, JR, Ghivizzani, SC and Evans, CH (2002). Gene transfer approaches to the healing of bone and cartilage. Mol Ther 6: 141-147.
    • (2002) Mol Ther , vol.6 , pp. 141-147
    • Lieberman, J.R.1    Ghivizzani, S.C.2    Evans, C.H.3
  • 122
    • 29744465669 scopus 로고    scopus 로고
    • Gene therapy for cartilage defects
    • Cucchiarini, M and Madry, H (2005). Gene therapy for cartilage defects. J Gene Med 7: 1495-1509.
    • (2005) J Gene Med , vol.7 , pp. 1495-1509
    • Cucchiarini, M.1    Madry, H.2
  • 123
    • 31644440253 scopus 로고    scopus 로고
    • Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo
    • Kaul, G, Cucchiarini, M, Amtzen, D, Zurakowski, D, Menger, MD, Kohn, D et al. (2006). Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo. J Gene Med 8: 100-111.
    • (2006) J Gene Med , vol.8 , pp. 100-111
    • Kaul, G.1    Cucchiarini, M.2    Amtzen, D.3    Zurakowski, D.4    Menger, M.D.5    Kohn, D.6
  • 124
    • 33747609579 scopus 로고    scopus 로고
    • Direct adenovirus-mediated IGF-I gene transduction of synovium induces persisting synovial fluid IGF-I ligand elevations
    • Goodrich, LR, Brower-Toland, BD, Warnick, L, Robbins, PD, Evans, CH and Nixon, AJ (2006). Direct adenovirus-mediated IGF-I gene transduction of synovium induces persisting synovial fluid IGF-I ligand elevations. Gene Ther 13: 1253-1262.
    • (2006) Gene Ther , vol.13 , pp. 1253-1262
    • Goodrich, L.R.1    Brower-Toland, B.D.2    Warnick, L.3    Robbins, P.D.4    Evans, C.H.5    Nixon, A.J.6
  • 125
    • 29244437207 scopus 로고    scopus 로고
    • Repair of articular cartilage defect by intraarticular administration of basic fibroblast growth factor gene, using adeno-associated virus vector
    • Hiraide, A, Yokoo, N, Xin, KQ, Okuda, K, Mizukami, H, Ozawa, K et al. (2005). Repair of articular cartilage defect by intraarticular administration of basic fibroblast growth factor gene, using adeno-associated virus vector. Hum Gene Ther 16: 1413-1421.
    • (2005) Hum Gene Ther , vol.16 , pp. 1413-1421
    • Hiraide, A.1    Yokoo, N.2    Xin, K.Q.3    Okuda, K.4    Mizukami, H.5    Ozawa, K.6
  • 126
    • 4344595112 scopus 로고    scopus 로고
    • Enhanced repair of the anterior cruciate ligament by in situ gene transfer: Evaluation in an in vitro model
    • Pascher, A, Steinert, AF, Palmer, GD, Betz, O, Gouze, JN, Gouze, E et al. (2004). Enhanced repair of the anterior cruciate ligament by in situ gene transfer: Evaluation in an in vitro model. Mol Ther 10: 327-336.
    • (2004) Mol Ther , vol.10 , pp. 327-336
    • Pascher, A.1    Steinert, A.F.2    Palmer, G.D.3    Betz, O.4    Gouze, J.N.5    Gouze, E.6
  • 127
    • 9244245810 scopus 로고    scopus 로고
    • Menisci are efficiently transduced by recombinant adeno-associated virus vectors in vitro and in vivo
    • Madry, H, Cucchiarini, M, Kaul, G, Kohn, D, Terwilliger, EF, Trippel, SB et al. (2004). Menisci are efficiently transduced by recombinant adeno-associated virus vectors in vitro and in vivo. Am J Sports Med 32: 1860-1865.
    • (2004) Am J Sports Med , vol.32 , pp. 1860-1865
    • Madry, H.1    Cucchiarini, M.2    Kaul, G.3    Kohn, D.4    Terwilliger, E.F.5    Trippel, S.B.6
  • 128
    • 0346906569 scopus 로고    scopus 로고
    • Gene therapy and tissue engineering for sports medicine
    • Huard, J, Li, Y, Peng, H and Fu, FH (2003). Gene therapy and tissue engineering for sports medicine. J Gene Med 5: 93-108.
    • (2003) J Gene Med , vol.5 , pp. 93-108
    • Huard, J.1    Li, Y.2    Peng, H.3    Fu, F.H.4
  • 130
    • 34548160395 scopus 로고    scopus 로고
    • Reduction of arthritis following intra-articular administration of an adeno-associated virus serotype 5 expressing a disease-inducible TNF-blocking agent
    • epub ahead of print
    • Adriaansen, J, Khoury, M, de Cortie, CJ, Fallaux, FJ, Bigey, P, Scherman, D et al. (2007). Reduction of arthritis following intra-articular administration of an adeno-associated virus serotype 5 expressing a disease-inducible TNF-blocking agent. Ann Rheum Dis epub ahead of print.
    • (2007) Ann Rheum Dis
    • Adriaansen, J.1    Khoury, M.2    de Cortie, C.J.3    Fallaux, F.J.4    Bigey, P.5    Scherman, D.6
  • 131
    • 17144414173 scopus 로고    scopus 로고
    • Gene gun particle encoding preproenkephalin cDNA produces analgesia against capsaicin-induced bladder pain in rats
    • Chuang, YC, Yang, LC, Chiang, PH, Kang, HY, Ma, WL, Wu, PC et al. (2005). Gene gun particle encoding preproenkephalin cDNA produces analgesia against capsaicin-induced bladder pain in rats. Urology 65: 804-810.
    • (2005) Urology , vol.65 , pp. 804-810
    • Chuang, Y.C.1    Yang, L.C.2    Chiang, P.H.3    Kang, H.Y.4    Ma, W.L.5    Wu, P.C.6
  • 132
    • 0242333885 scopus 로고    scopus 로고
    • Development of HSV-medlated gene transfer for the treatment of chronic pain
    • Mata, M, Glorioso, J and Fink, DJ (2003). Development of HSV-medlated gene transfer for the treatment of chronic pain. Exp Neurol 184 (suppl. 1): S25-S29.
    • (2003) Exp Neurol , vol.184 , Issue.SUPPL. 1
    • Mata, M.1    Glorioso, J.2    Fink, D.J.3
  • 133
    • 20444402960 scopus 로고    scopus 로고
    • Gene transfer of glutamic acid decarboxylase reduces neuropathic pain
    • Hao, S, Mata, M, Wolfe, D, Huang, S, Glorioso, JC and Fink, DJ (2005). Gene transfer of glutamic acid decarboxylase reduces neuropathic pain. Ann Neurol 57: 914-918.
    • (2005) Ann Neurol , vol.57 , pp. 914-918
    • Hao, S.1    Mata, M.2    Wolfe, D.3    Huang, S.4    Glorioso, J.C.5    Fink, D.J.6
  • 134
    • 2942716688 scopus 로고    scopus 로고
    • Regulated, electroporation-mediated delivery of pro-opiomelanocortin gene suppresses chronic constriction injury-induced neuropathic pain in rats
    • Wu, CM, Lin, MW, Cheng, JT, Wang, YM, Huang, YW, Sun, WZ et al. (2004). Regulated, electroporation-mediated delivery of pro-opiomelanocortin gene suppresses chronic constriction injury-induced neuropathic pain in rats. Gene Ther 11: 933-940.
    • (2004) Gene Ther , vol.11 , pp. 933-940
    • Wu, C.M.1    Lin, M.W.2    Cheng, J.T.3    Wang, Y.M.4    Huang, Y.W.5    Sun, W.Z.6
  • 135
    • 33646409615 scopus 로고    scopus 로고
    • HSV-mediated expression of interleukin-4 in dorsal root ganglion neurons reduces neuropathic pain
    • Hao, S, Mata, M, Glorioso, JC and Fink, DJ (2006). HSV-mediated expression of interleukin-4 in dorsal root ganglion neurons reduces neuropathic pain. Mol Pain 2: 6.
    • (2006) Mol Pain , vol.2 , pp. 6
    • Hao, S.1    Mata, M.2    Glorioso, J.C.3    Fink, D.J.4
  • 137
    • 0036181286 scopus 로고    scopus 로고
    • No DREAM, No pain. Closing the spinal gate
    • Costigan, M and Woolf, CJ (2002). No DREAM, No pain. Closing the spinal gate. Cell 108: 297-300.
    • (2002) Cell , vol.108 , pp. 297-300
    • Costigan, M.1    Woolf, C.J.2
  • 138
    • 17144368801 scopus 로고    scopus 로고
    • Genes and human elite athletic performance
    • Macarthur, DG and North, KN (2005). Genes and human elite athletic performance. Hum Genet 116: 331-339.
    • (2005) Hum Genet , vol.116 , pp. 331-339
    • Macarthur, D.G.1    North, K.N.2
  • 140
    • 23644445367 scopus 로고    scopus 로고
    • Mitochondrial DNA and ACTN3 genotypes in Finnish elite endurance and sprint athletes
    • Niemi, AK and Majamaa, K (2005). Mitochondrial DNA and ACTN3 genotypes in Finnish elite endurance and sprint athletes. Eur J Hum Genet 13: 965-969.
    • (2005) Eur J Hum Genet , vol.13 , pp. 965-969
    • Niemi, A.K.1    Majamaa, K.2
  • 141
    • 34447550642 scopus 로고    scopus 로고
    • Activin-type II receptor B (ACVR2B) and follistatin haplotype associations with muscle mass and strength in humans
    • Walsh, S, Metter, EJ, Ferrucci, L and Roth, SM (2007). Activin-type II receptor B (ACVR2B) and follistatin haplotype associations with muscle mass and strength in humans. J Appl Physiol 102: 2142-2148.
    • (2007) J Appl Physiol , vol.102 , pp. 2142-2148
    • Walsh, S.1    Metter, E.J.2    Ferrucci, L.3    Roth, S.M.4


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