-
2
-
-
0037189401
-
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning
-
Aiuti A, Slavin S, Aker M, Ficara F, Deola S, Mortellaro A, Morecki S, Andolfi G, Tabucchi A, Carlucci F, Marinello E, Cattaneo F, Vai S, Servida P, Miniero R, Roncarolo MG, Bordignon C. Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning. Sci 2002; 296: 2410-2413
-
(2002)
Sci
, vol.296
, pp. 2410-2413
-
-
Aiuti, A.1
Slavin, S.2
Aker, M.3
Ficara, F.4
Deola, S.5
Mortellaro, A.6
Morecki, S.7
Andolfi, G.8
Tabucchi, A.9
Carlucci, F.10
Marinello, E.11
Cattaneo, F.12
Vai, S.13
Servida, P.14
Miniero, R.15
Roncarolo, M.G.16
Bordignon, C.17
-
4
-
-
0035661268
-
Lack of germline transmission of vector sequences following systemic administration of recombinant AAV-2 vector in males
-
Arruda VR, Fields PA, Milner R, Wainwright L, De Miguel MP, Donovan PJ, Herzog RW, Nichols TC, Biegel JA, Razavi M, Dake M, Huff D, Flake AW, Couto L, Kay MA, High KA. Lack of germline transmission of vector sequences following systemic administration of recombinant AAV-2 vector in males. Mol Ther 2001; 4: 586-592
-
(2001)
Mol Ther
, vol.4
, pp. 586-592
-
-
Arruda, V.R.1
Fields, P.A.2
Milner, R.3
Wainwright, L.4
De Miguel, M.P.5
Donovan, P.J.6
Herzog, R.W.7
Nichols, T.C.8
Biegel, J.A.9
Razavi, M.10
Dake, M.11
Huff, D.12
Flake, A.W.13
Couto, L.14
Kay, M.A.15
High, K.A.16
-
6
-
-
0032416479
-
Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function
-
Barton-Davis ER, Shoturma DI, Musaro A, Rosenthal N, Sweeney HL. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. Proc Natl Acad Sci USA 1998; 95: 15603-15607
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15603-15607
-
-
Barton-Davis, E.R.1
Shoturma, D.I.2
Musaro, A.3
Rosenthal, N.4
Sweeney, H.L.5
-
7
-
-
0032583951
-
Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia
-
Baumgartner I, Pieczek A, Manor O, Blair R, Kearney M, Walsh K, Isner JM. Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circul 1998; 97: 1114-1123
-
(1998)
Circul
, vol.97
, pp. 1114-1123
-
-
Baumgartner, I.1
Pieczek, A.2
Manor, O.3
Blair, R.4
Kearney, M.5
Walsh, K.6
Isner, J.M.7
-
8
-
-
0037191752
-
Functional improvement of dystrophic muscle by myostatinblockade
-
Bogdanovich S, Krag TO, Barton ER, Morris LD, Whittemore LA, Ahima RS, Khurana TS. Functional improvement of dystrophic muscle by myostatinblockade. Nature 2002; 420; 418-421
-
(2002)
Nature
, vol.420
, pp. 418-421
-
-
Bogdanovich, S.1
Krag, T.O.2
Barton, E.R.3
Morris, L.D.4
Whittemore, L.A.5
Ahima, R.S.6
Khurana, T.S.7
-
9
-
-
10944271807
-
Efficacy of gene therapy for SCID is being confirmed
-
Cavazzana-Calvo M, Fischer A. Efficacy of gene therapy for SCID is being confirmed. Lancet 2004; 364: 2155-2156
-
(2004)
Lancet
, vol.364
, pp. 2155-2156
-
-
Cavazzana-Calvo, M.1
Fischer, A.2
-
10
-
-
1942521650
-
Autoimmune anemia in macaques following erythropoietin gene therapy
-
Chenuaud P, Larcher T, Rabinowitz JE, Provost N, Cherel Y, Casadevall N, Samulski RJ, Mouiller P. Autoimmune anemia in macaques following erythropoietin gene therapy. Blood 2004; 103: 3303-3304
-
(2004)
Blood
, vol.103
, pp. 3303-3304
-
-
Chenuaud, P.1
Larcher, T.2
Rabinowitz, J.E.3
Provost, N.4
Cherel, Y.5
Casadevall, N.6
Samulski, R.J.7
Mouiller, P.8
-
11
-
-
0036447546
-
Opinion paper on the current status of the regulation of gene therapy in Europe
-
Cohen-Haguenauer O, Rosenthal F, Gansbacher B, Bolhuis R, Dorsch-Hasler K, Eshhar Z, Gahrton G, Hokland P, Melani C, Rankin E. Thielemans K, Vile R, Zwierzina H, Cichutek K. Opinion paper on the current status of the regulation of gene therapy in Europe. Hum Gene Ther 2002; 13: 2085-2110
-
(2002)
Hum Gene Ther
, vol.13
, pp. 2085-2110
-
-
Cohen-Haguenauer, O.1
Rosenthal, F.2
Gansbacher, B.3
Bolhuis, R.4
Dorsch-Hasler, K.5
Eshhar, Z.6
Gahrton, G.7
Hokland, P.8
Melani, C.9
Rankin, E.10
Thielemans, K.11
Vile, R.12
Zwierzina, H.13
Cichutek, K.14
-
13
-
-
4444268850
-
The faking of champions
-
DeFrancesco L. The faking of champions. Nat Biotechnol 2004; 22: 1069-1071
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1069-1071
-
-
DeFrancesco, L.1
-
15
-
-
1942457251
-
Erythropoietin gene therapy leads to autoimmune anemia in macaques
-
Gao G, Lebherz C, Weiner DJ, Grant R, Calcedo R, McCullough B, Bagg A, Zhang Y, Wilson JM. Erythropoietin gene therapy leads to autoimmune anemia in macaques. Blood 2004; 103: 3300-3302
-
(2004)
Blood
, vol.103
, pp. 3300-3302
-
-
Gao, G.1
Lebherz, C.2
Weiner, D.J.3
Grant, R.4
Calcedo, R.5
McCullough, B.6
Bagg, A.7
Zhang, Y.8
Wilson, J.M.9
-
16
-
-
0037344533
-
Recombinant adenovirus shedding after intratumoral gene transfer in lung cancer patients
-
Griscelli F, Opolon P, Saulnier P, Mami-Chouaib F, Gautier E, Echchakir H, Angevin E, Le CT, Bataille V, Squiban P, Tursz T, Escudier B. Recombinant adenovirus shedding after intratumoral gene transfer in lung cancer patients. Gene Ther 2003; 10: 386-395
-
(2003)
Gene Ther
, vol.10
, pp. 386-395
-
-
Griscelli, F.1
Opolon, P.2
Saulnier, P.3
Mami-Chouaib, F.4
Gautier, E.5
Echchakir, H.6
Angevin, E.7
Le, C.T.8
Bataille, V.9
Squiban, P.10
Tursz, T.11
Escudier, B.12
-
17
-
-
0037129435
-
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy
-
Hacein-Bey-Abina S, Le DF, Carlier F, Bouneaud C, Hue C, De Villartay JP, Thrasher AJ, Wulffraat N, Sorensen R, Dupuis-Girod S, Fischer A, Davies EG, Kuis W, Leiva L, Cavazzana-Calvo M. Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy. N Engl J Med 2002; 346: 1185-1193
-
(2002)
N Engl J Med
, vol.346
, pp. 1185-1193
-
-
Hacein-Bey-Abina, S.1
Le, D.F.2
Carlier, F.3
Bouneaud, C.4
Hue, C.5
De Villartay, J.P.6
Thrasher, A.J.7
Wulffraat, N.8
Sorensen, R.9
Dupuis-Girod, S.10
Fischer, A.11
Davies, E.G.12
Kuis, W.13
Leiva, L.14
Cavazzana-Calvo, M.15
-
18
-
-
0346906569
-
Gene therapy and tissue engineering for sports medicine
-
Huard J, Li Y, Peng H, Fu FH. Gene therapy and tissue engineering for sports medicine. J Gene Med 2003; 5: 93-108
-
(2003)
J Gene Med
, vol.5
, pp. 93-108
-
-
Huard, J.1
Li, Y.2
Peng, H.3
Fu, F.H.4
-
19
-
-
0034050904
-
Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
-
Kay MA, Manno CS, Ragni MV, Larson PJ, Couto LB, McClelland A, Glader B, Chew AJ, Tai SJ, Herzog RW, Arruda V, Johnson F, Scallan C, Skarsgard E, Flake AW, High KA. Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector. Nat Genet 2000; 24: 257-261
-
(2000)
Nat Genet
, vol.24
, pp. 257-261
-
-
Kay, M.A.1
Manno, C.S.2
Ragni, M.V.3
Larson, P.J.4
Couto, L.B.5
McClelland, A.6
Glader, B.7
Chew, A.J.8
Tai, S.J.9
Herzog, R.W.10
Arruda, V.11
Johnson, F.12
Scallan, C.13
Skarsgard, E.14
Flake, A.W.15
High, K.A.16
-
20
-
-
11844303500
-
Recent developments in gene transfer: Risk and ethics
-
Kimmelman J. Recent developments in gene transfer: risk and ethics. BMJ 2005; 330: 79-82
-
(2005)
BMJ
, vol.330
, pp. 79-82
-
-
Kimmelman, J.1
-
21
-
-
20044378094
-
Tetrahydrogestrinone induces a genomic signature typical of a potent anabolic steroid
-
Labrie F, Luu-The V, Calvo E, Martel C, Cloutier J, Gauthier S, Belleau P, Morissette J, Levesque MH, Labrie C. Tetrahydrogestrinone induces a genomic signature typical of a potent anabolic steroid. J Endocrinol 2005; 184: 427-433
-
(2005)
J Endocrinol
, vol.184
, pp. 427-433
-
-
Labrie, F.1
Luu-The, V.2
Calvo, E.3
Martel, C.4
Cloutier, J.5
Gauthier, S.6
Belleau, P.7
Morissette, J.8
Levesque, M.H.9
Labrie, C.10
-
22
-
-
34547493681
-
Cyclist's doping associated with cerebral sinus thrombosis
-
Lage JM, Panizo C, Masdeu J, Rocha E. Cyclist's doping associated with cerebral sinus thrombosis. Neurol 2002; 58: 665
-
(2002)
Neurol
, vol.58
, pp. 665
-
-
Lage, J.M.1
Panizo, C.2
Masdeu, J.3
Rocha, E.4
-
23
-
-
4444305201
-
"Genetic Doping" with erythropoietin cDNA in primate muscle is detectable
-
Lasne F, Martin L, de Ceaurriz J, Larcher T, Moullier P, Chenuaud P. "Genetic Doping" with erythropoietin cDNA in primate muscle is detectable. Mol Ther 2004; 10: 409-410
-
(2004)
Mol Ther
, vol.10
, pp. 409-410
-
-
Lasne, F.1
Martin, L.2
De Ceaurriz, J.3
Larcher, T.4
Moullier, P.5
Chenuaud, P.6
-
24
-
-
1342325478
-
Viral expression of insulin-like growth factor-I enhances muscle hypertrophy in resistance-trained rats
-
Lee S, Barton ER, Sweeney HL, Farrar RP. Viral expression of insulin-like growth factor-I enhances muscle hypertrophy in resistance-trained rats. J Appl Physiol 2004; 96: 1097-1104
-
(2004)
J Appl Physiol
, vol.96
, pp. 1097-1104
-
-
Lee, S.1
Barton, E.R.2
Sweeney, H.L.3
Farrar, R.P.4
-
25
-
-
0035979253
-
Regulation of myostatin activity and muscle growth
-
Lee SJ, McPherron AC. Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci USA 2001; 98: 9306-9311
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9306-9311
-
-
Lee, S.J.1
McPherron, A.C.2
-
26
-
-
0036737749
-
Electroporation-mediated pain-killer gene therapy for mononeuropathic rats
-
Lin CR, Yang LC, Lee TH, Lee CT, Huang HT, Sun WZ, Cheng JT. Electroporation-mediated pain-killer gene therapy for mononeuropathic rats. Gene Ther 2002; 9: 1247-1253
-
(2002)
Gene Ther
, vol.9
, pp. 1247-1253
-
-
Lin, C.R.1
Yang, L.C.2
Lee, T.H.3
Lee, C.T.4
Huang, H.T.5
Sun, W.Z.6
Cheng, J.T.7
-
27
-
-
0037197740
-
Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia
-
Losordo DW, Vale PR, Hendel RC, Milliken CE, Fortuin FD, Cummings N, Schatz RA, Asahara T, Isner JM, Kuntz RE. Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia. Circul 2002; 105: 2012-2018
-
(2002)
Circul
, vol.105
, pp. 2012-2018
-
-
Losordo, D.W.1
Vale, P.R.2
Hendel, R.C.3
Milliken, C.E.4
Fortuin, F.D.5
Cummings, N.6
Schatz, R.A.7
Asahara, T.8
Isner, J.M.9
Kuntz, R.E.10
-
28
-
-
14644435182
-
The growth factor myostatin, a key regulator in skeletal muscle growth and homeostasis
-
Matsakas A, Diel P. The growth factor myostatin, a key regulator in skeletal muscle growth and homeostasis. Int J Sports Med 2005; 26: 83-89
-
(2005)
Int J Sports Med
, vol.26
, pp. 83-89
-
-
Matsakas, A.1
Diel, P.2
-
29
-
-
0033950285
-
Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer
-
Nemunaitis J, Swisher SG, Timmons T, Connors D, Mack M, Doerksen L, Weill D, Wait J, Lawrence DD, Kemp BL, Fossella F, Glisson BS, Hong WK, Khuri FR, Kurie JM, Lee JJ, Lee JS, Nguyen DM, Nesbitt JC, Perez-Soler R, Pisters KM, Putnam JB, Richli WR, Shin DM, Walsh GL, Merritt J, Roth J. Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer. J Clin Oncol 2000; 18: 609-622
-
(2000)
J Clin Oncol
, vol.18
, pp. 609-622
-
-
Nemunaitis, J.1
Swisher, S.G.2
Timmons, T.3
Connors, D.4
Mack, M.5
Doerksen, L.6
Weill, D.7
Wait, J.8
Lawrence, D.D.9
Kemp, B.L.10
Fossella, F.11
Glisson, B.S.12
Hong, W.K.13
Khuri, F.R.14
Kurie, J.M.15
Lee, J.J.16
Lee, J.S.17
Nguyen, D.M.18
Nesbitt, J.C.19
Perez-Soler, R.20
Pisters, K.M.21
Putnam, J.B.22
Richli, W.R.23
Shin, D.M.24
Walsh, G.L.25
Merritt, J.26
Roth, J.27
more..
-
31
-
-
0142023866
-
Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: A phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication
-
Rajagopalan S, Mohler ER, III, Lederman RJ, Mendelsohn FO, Saucedo JF, Goldman CK, Blebea J, Macko J, Kessler PD, Rasmussen HS, Annex BH. Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circul 2003; 108: 1933-1938
-
(2003)
Circul
, vol.108
, pp. 1933-1938
-
-
Rajagopalan, S.1
Mohler III, E.R.2
Lederman, R.J.3
Mendelsohn, F.O.4
Saucedo, J.F.5
Goldman, C.K.6
Blebea, J.7
Macko, J.8
Kessler, P.D.9
Rasmussen, H.S.10
Annex, B.H.11
-
32
-
-
4444377863
-
The human gene map for performance and health-related fitness phenotypes: The 2003 update
-
Rankinen T, Perusse L, Rauramaa R, Rivera MA, Wolfarth B, Bouchard C. The human gene map for performance and health-related fitness phenotypes: the 2003 update. Med Sci Sports Exerc 2004; 36: 1451-1469
-
(2004)
Med Sci Sports Exerc
, vol.36
, pp. 1451-1469
-
-
Rankinen, T.1
Perusse, L.2
Rauramaa, R.3
Rivera, M.A.4
Wolfarth, B.5
Bouchard, C.6
-
33
-
-
0142089747
-
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
-
Raper SE, Chirmule N, Lee FS, Wivel NA, Bagg A, Gao GP, Wilson JM, Batshaw ML. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 2003; 80: 148-158
-
(2003)
Mol Genet Metab
, vol.80
, pp. 148-158
-
-
Raper, S.E.1
Chirmule, N.2
Lee, F.S.3
Wivel, N.A.4
Bagg, A.5
Gao, G.P.6
Wilson, J.M.7
Batshaw, M.L.8
-
34
-
-
2942735123
-
Myostatin mutation associated with gross muscle hypertrophy in a child
-
Schuelke M, Wagner KR, Stolz LE, Hubner C, Riebel T, Komen W, Braun T, Tobin JF, Lee SJ. Myostatin mutation associated with gross muscle hypertrophy in a child. N Engl J Med 2004; 350: 2682-2688
-
(2004)
N Engl J Med
, vol.350
, pp. 2682-2688
-
-
Schuelke, M.1
Wagner, K.R.2
Stolz, L.E.3
Hubner, C.4
Riebel, T.5
Komen, W.6
Braun, T.7
Tobin, J.F.8
Lee, S.J.9
-
35
-
-
0033522939
-
Nota bene: Biomedicine. Pain-killer genes
-
Smith O. Nota bene: biomedicine. Pain-killer genes. Sci 1999; 284: 1634
-
(1999)
Sci
, vol.284
, pp. 1634
-
-
Smith, O.1
-
36
-
-
2142751261
-
Evaluation of risks related to the use of adeno-associated virus-based vectors
-
Tenenbaum L, Lehtonen E, Monahan PE. Evaluation of risks related to the use of adeno-associated virus-based vectors. Curr Gene Ther 2003; 3: 545-565
-
(2003)
Curr Gene Ther
, vol.3
, pp. 545-565
-
-
Tenenbaum, L.1
Lehtonen, E.2
Monahan, P.E.3
-
37
-
-
27544465879
-
Functional characteristics of coronary vasomotor function following intramyocardial gene therapy with naked DNA encoding for vascular endothelial growth factor 165
-
Tio RA, Wijpkema JS, Tan ES, Asselbergs FW, Hospers GA, Jessurun GA, Zijlstra F. Functional characteristics of coronary vasomotor function following intramyocardial gene therapy with naked DNA encoding for vascular endothelial growth factor 165. Endothelium 2005; 12: 103-106
-
(2005)
Endothelium
, vol.12
, pp. 103-106
-
-
Tio, R.A.1
Wijpkema, J.S.2
Tan, E.S.3
Asselbergs, F.W.4
Hospers, G.A.5
Jessurun, G.A.6
Zijlstra, F.7
-
38
-
-
0036202668
-
A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with AIDS
-
Vitravene Study Group. A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with AIDS. Am J Ophthalmol 2002; 133: 467-474
-
(2002)
Am J Ophthalmol
, vol.133
, pp. 467-474
-
-
-
40
-
-
0036280779
-
Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry
-
Wu W, Tang X, Hu W, Lotan R, Hong WK, Mao L. Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry. Clin Exp Metastasis 2002; 19: 319-326
-
(2002)
Clin Exp Metastasis
, vol.19
, pp. 319-326
-
-
Wu, W.1
Tang, X.2
Hu, W.3
Lotan, R.4
Hong, W.K.5
Mao, L.6
-
41
-
-
0032949030
-
Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer
-
Ye X, Rivera VM, Zoltick P, Cerasoli F Jr, Schnell MA, Gao G, Hughes JV, Gilman M, Wilson JM. Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer. Sci 1999; 283: 88-91
-
(1999)
Sci
, vol.283
, pp. 88-91
-
-
Ye, X.1
Rivera, V.M.2
Zoltick, P.3
Cerasoli Jr., F.4
Schnell, M.A.5
Gao, G.6
Hughes, J.V.7
Gilman, M.8
Wilson, J.M.9
-
42
-
-
0031834034
-
Adeno-associated virus-mediated delivery of erythropoietin leads to sustained elevation of hematocrit in nonhuman primates
-
Zhou S, Murphy JE, Escobedo JA, Dwarki VJ. Adeno-associated virus-mediated delivery of erythropoietin leads to sustained elevation of hematocrit in nonhuman primates. Gene Ther 1998; 5: 665-670
-
(1998)
Gene Ther
, vol.5
, pp. 665-670
-
-
Zhou, S.1
Murphy, J.E.2
Escobedo, J.A.3
Dwarki, V.J.4
|