Organocatalytic and highly enantioselective direct α-amination of aromatic ketones

Organic Letters

Volumn 9, Issue 18, 2007, Pages 3671-3674

  Liu, Tian Yu ^a   Cui, Hai Lei ^a   Zhang, Yan ^a   Jiang, Kun ^a   Du, Wei ^a   He, Zhao Quan ^a   Chen, Ying Chun ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; AROMATIC HYDROCARBON; KETONE; ORGANIC COMPOUND;

AMINATION; ARTICLE; CATALYSIS; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

AMINATION; AMINES; CATALYSIS; HYDROCARBONS, AROMATIC; KETONES; ORGANIC CHEMICALS; STEREOISOMERISM;

EID: 34548537133     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol701648x     Document Type: Article

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74. Apart from the promotion of enamine formation, the presence of 4 Å MS may also be helpful for this hydrogen-bonding activation to improve the enantioselectivity.