Synthesis of β-hydroxyaldehydes with stereogenic quaternary carbon centers by direct organocatalytic asymmetric aldol reactions

Angewandte Chemie - International Edition

Volumn 43, Issue 18, 2004, Pages 2420-2423

  Mase, Nobuyuki ^b   Tanaka, Fujie ^a   Barbas III, Carlos F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b SHIZUOKA UNIVERSITY   (Japan)

Author keywords

Aldol reaction; Asymmetric catalysis; Enantioselectivity; High throughput screening; Organocatalysis

Indexed keywords

ALDEHYDES; BROMINE; CATALYSTS; CHLORINE; FLUORESCENCE; NITROGEN OXIDES;

ALDOL REACTIONS; BIFUNCTIONAL CATALYSTS; FLUORESCENCE DETECTION SYSTEMS;

STEREOCHEMISTRY;

CARBON; HYDROXYALDEHYDE; 3-HYDROXYBUTANAL; ACID; ALDEHYDE; ALDOL; AMINE;

ALDOL REACTION; ARTICLE; ASYMMETRIC CATALYSIS; CATALYST; CHEMICAL REACTION; ENANTIOSELECTIVITY; MOLECULAR INTERACTION; REACTION ANALYSIS; SYNTHESIS; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HYDROXYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM;

ACIDS; ALDEHYDES; AMINES; CARBON; CATALYSIS; HYDROXYLATION; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 3042625080     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200353546     Document Type: Article

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