NIMH genetics initiative millennium Schizophrenia consortium: Linkage analysis of African-American pedigrees

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 81, Issue 4, 1998, Pages 282-289

  Kaufmann, Charles A ^a   Suarez, Brian ^b   Malaspina, Dolores ^a   Pepple, John ^c   Svrakic, Dragan ^b   Markel, Paul D ^d   Meyer, Joanne ^d   Zambuto, Christopher T ^d   Schmitt, Karin ^d   Matise, Tara Cox ^e   Friedman, Jill M Harkavy ^a   Hampe, Carol ^b   Lee, Hang ^c   Shore, David ^f   Wynne, Debra ^f   Faraone, Stephen V ^c   Tsuang, Ming T ^c   Cloninger, C Robert ^b  

^a Columbia University ^*  (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d MILLENNIUM PHARMACEUTICALS INC   (United States)

^e ROCKEFELLER UNIVERSITY   (United States)

^f NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

African American; Linkage analysis; NIMH Genetics Initiative; Schizophrenia

Indexed keywords

DNA;

ADULT; ARTICLE; CHROMOSOME 15P; CHROMOSOME 19; CHROMOSOME 4; CHROMOSOME 6Q; CHROMOSOME 8P; CHROMOSOME 9Q; CONTROLLED STUDY; DEPRESSION; FEMALE; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NEGRO; PEDIGREE ANALYSIS; PRIORITY JOURNAL; SCHIZOIDISM; SCHIZOPHRENIA; TANDEM REPEAT;

ADOLESCENT; ADULT; AFRICAN AMERICANS; AFRICAN CONTINENTAL ANCESTRY GROUP; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 19; CHROMOSOMES, HUMAN, PAIR 4; CHROMOSOMES, HUMAN, PAIR 6; CHROMOSOMES, HUMAN, PAIR 8; CHROMOSOMES, HUMAN, PAIR 9; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE (GENETICS); MALE; MIDDLE AGED; NATIONAL INSTITUTES OF HEALTH (U.S.); PEDIGREE; REPETITIVE SEQUENCES, NUCLEIC ACID; SCHIZOPHRENIA; UNITED STATES;

EID: 0032503891     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19980710)81:4<282::AID-AJMG2>3.0.CO;2-W     Document Type: Article

References (31)

1. Antonorakis SE, Blouin JL, Pulver AE, Wolyniec P, Lasseter VK, Nestadt G, Kasch L, Babb R, Kazazian HH (1995): Dombroski Schizophrenia susceptibility and chromosome 6p24-22 Nature Genet 11:235-236.
2. Babron MC, Martinez M, Bonaiti-Pellie G, Clerget-Darpoux F (1993): Linkage detection by the Affected-Pedigrce-Member method: What is really tested? Genet Epidemiol 10:389-394.
3. Bowman JF, Murray RF Jr (1990): "Genetic Variation and Disorders in Peoples of African Origin." Baltimore: The Johns Hopkins University Press.
4. Calzolaru IE, Aiello V, Palazzi P, Sensi A, Calzolari S, Orrico D, Calliari L, Holler H, Marzi C, Belli S, Bernardi F, Patracchini P (1996): Psychiatric disorder in a familial 15:18 translocation and sublocalization of myelin basic protein to 18q22.3. Am J Med Genet 67:154-161.
5. Chakraborty R, Kamboh MI, Nwankwo M, Ferrell RE (1992): Caucasian genes in American blacks: New data. Am J Hum Genet 50:145-155.
6. Chen YR, Swann AC, Burt DB (1996): Stability of diagnosis in schizophrenia. Am J of Psychiatry 153:682-686.
7. Cloninger CR (1994): "The Temperament and Character Inventory (TCI): A Guide to Its Development and Use." St. Louis: Center for Psychobiology of Personality.
8. Cloninger CR, Van Eerdewegh P, Goate A, Edenberg Hj, Blangero J, Hesselbrock V, Reich T, Nurnberger J Jr, Schuckit M, Porjesz B, Crowe R, Rice JP, Foroud T, Przybeck TR, Almasy L, Bucholz K, Wu W, Shears S, Carr K, Crose C, Willig C, Zhou J, Tischfield JA, Li TK, Conneally PM, Begleiter H (1998): Anxiety proneness linked to epistatic loci in genome scan of human personality traits. Nature (in press).
9. Cloninger CR, Kaufmann CA, Faraone SV, Malaspina D, Svrakic DM, Harkavy-Friedman J, Suarez BK, Matise TC, Shore D, Lee H, Hampe CL, Wynne D, Drain C, Markel PD, Zambuto CT, Schmitt K, Tsuang MT (1998): Genome-wide search for schizophrenia susceptibility loci: The NIMH Genetics Initiative and Mmillennium Consortium. Am J Med Genet 81:275-281.
10. Collaborative Study on the Genetics of Asthma, The (CSGA) (1997): A genome-wide search for asthma susceptibiltiy loci in ethnically diverse populations. Nature Genet 15:389-392.
11. Collins A, Frezal J, Teague J, Morton NE (1996): A metric map of humans: 23,500 loci in 850 bands. Proceedings of the National Academy of Sciences (USA) 93:14771-14775, 1996.
12. Coon H, Jensen S, Holik J, Hoff M, Myles-Worsley M, Reimherr F, Wender P, Waldo M, Freedman R, Leppert M (1994): Genomic scan for genes predisposing to schizophrenia. Am J Med Genet 54:59-71.
13. Dean M, Stephens JC, Winkler C, Lomb DA, Ramsburg M, Boaze R, Stewart C, Charbonneau L, Goldman D, Albaugh BJ (1994): Polymorphic admixture typing in human ethnic populations. Am J Hum Genet 55: 788-808.
14. Delepine M, Pociot F, Habita C, Hashimoto L, Froguel P, Rotter J, Cambon-Thomsen A, Deschamps I, Djoulah S, Weissenbach J, Nerup J, Lathrop M, Julier C (1997): Evidence of a non-MHC susceptibility locus in type I diabetes linked to HLA on chromosome 6. Am J Hum Genet 60:174-187.
15. Earle KA, Forquer SL, Volo AM, McDonnell PM (1994): Characteristics of outpatient suicides. Hospital and Comm Psychiatry 45:123-126.
16. Ereshefsky L, Lacombe S (1993): Pharmacological profile of risperidone. Canadian J Psychiatry 38:SSO-S88.
17. Faraone SV, Matise T, Svrakic D, Pepple J, Malaspina D, Suzarez B, Hampe C, Zambuto CT, Schmitt K, Meyer J, Markel P, Lee H, Harkavy-Friedman J, Kaufmann C, Cloninger CR, Tsuang MT (1998): Genome scan of European-American schizophrenia pedigrees: Results of the NIMH Genetics Initiative and Millennium Consortium. Am J Med Genet 81:290-295.
18. Freedman R, Coon H, Myles-Worsley M, Orr-Urtreger A, Olincy A, Davis A, Polymeropoulos M, Holik J, Hopkins J, Hoff M, Rosenthal J, Waldo MC, Reimherr F, Wender P, Yaw J, Young DA, Breese CR, Adams C, Patterson D, Adler LE, Kruglyak L, Leonard S, Byerley W (1997): Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proceedings of the National Academy of Sciences (USA) 94:587-592.
19. Goodman AB (1994): A family history study of schizophrenia spectrum disorders suggests new candidate genes in schizophrenia and autism. Psychiatric Quart 65:287-297.
20. Harrison G, Owens D, Holton A, Neilson D, Boot D (1988): A prospective study of severe mental disorder in Afro-Carribean patients. Psychol Med 18:643-657.
21. Hartmann J, Keister R, Houlihan B, Thompson L, Baldwin R, Buse E, Driver B, Kuo M (1994): Diversity of ethnic and racial VNTR RFLP fixed-bin frequency distributions. Am J Hum Genet 55:1268-1278.
22. Hovatta I, Seppälä J, Pekkarinen P, Tanskanen A, Lönnqvist J, Peltonen L (1994): Linkage analysis in two schizophrenic families originating from a restricted subpopulation of Finland Psychiatric Genet 4:143-152.
23. Hutchinson G, Takei N, Fahy TA, Bhugra D, Gilvarry C, Moran P, Mallett R, Sham P, Leff J, Murray RM (1996): Morbid risk of schizophrenia in first-degree relatives of white and African-Carribean patients with psychosis Br J Psychiatry 169:776-780.
24. Jablensky A, Sartorious N, Ernberg G, Anker M, Körten A, Cooper JE, Day R, Bertelsen A (1992): Schizophrenia: manifestations, incidence, and course in different cultures: A World Health Organization ten country study. Psychol Med Monograph Suppl 20:1-97.
25. Kalsi G, Mankoo BS, Brynjolfsson J, Curtis D, Read T, Murphy P, Sharma T, Petursson H, Curling HM (1994): The Marian syndrome gene locus as a favoured locus for susceptibility to schizophrenia Psychiatric Genet 4:219-227, 1994.
26. Kendler KS, MacLean CJ, O'Neill FA, Burke J, Murphy B, Duke F, Shinkwin R, Easter SM, Webb BT, Zhange J, Walsh D, Straub RE (1996): Evidence for a schzophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families. Am J Psychiatry 153:1534-1540.
27. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES (1996): Parametric and nonparametric linkage analysis: A unified multipoint approach. Am J Hum Genet 58:1347-1363.
28. Kunugi H, Curtis D, Vallada HP, Nanko S, Powell JF, Murray RM, McGuffin P, Owen MJ, Gill M, Collier DA (1996): A linkage study of schizophrenia with DNA markers from chromosome 8p21-p22 in 25 multiplex families. Schizophrenia Res 22:61-68.
29. Lander E, Kruglyak L (1995): Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nature Genet 11: 241-247.
30. Luntz-Leybman V, Bickford P, Freedman R (1992): Cholinergic gating of response to auditory stimuli in rat hippocampus. Brain Res 587:130-136.
31. McGehee DS, Heath MJ, Gelber S, Devay P, Role LW (1995): Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science 269:1692-1696.