Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence

Journal of Biological Chemistry

Volumn 278, Issue 48, 2003, Pages 47361-47364

  Woo, Hyun Ae ^a,b   Kang, Sang Won ^a,c   Kim, Hyung Ki ^c   Yang, Kap Seok ^a   Chae, Ho Zoon ^b,d   Rhee, Sue Goo ^b  

^a Ewha Womans University   (South Korea)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c KSBC Building   (South Korea)

^d Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; CELLS; INORGANIC ACIDS; OXIDATION; PROTEINS;

CONSERVED ACTIVE SITE SEQUENCES;

BIOCHEMISTRY;

CYSTEINE; CYSTEINE SULFINIC ACID; HYDROGEN PEROXIDE; PEROXIREDOXIN; PHOSPHOSERINE; PHOSPHOTHREONINE;

ANTIBODY SPECIFICITY; ARTICLE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; OXIDATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEOMICS;

ANIMALS; BINDING SITES; CELL LINE; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; IMMUNOBLOTTING; MACROPHAGES; MICE; MITOCHONDRIA; OXYGEN; PEPTIDES; PEROXIDASES; PHOSPHOSERINE; PHOSPHOTHREONINE; PROTEINS; SENSITIVITY AND SPECIFICITY; SULFINIC ACIDS; TIME FACTORS;

EID: 0346850874     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300428200     Document Type: Article

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