Identification of distinct N-terminal truncated forms of prion protein in different Creutzfeldt-Jakob disease subtypes

Journal of Biological Chemistry

Volumn 279, Issue 37, 2004, Pages 38936-38942

  Zanusso, Gianluigi ^a   Farinazzo, Alessia ^a   Prelli, Frances ^b   Fiorini, Michele ^a   Gelati, Matteo ^a   Ferrari, Sergio ^a   Righetti, Pier Giorgio ^a   Rizzuto, Nicolò ^a   Frangiones, Blas ^b   Monaco, Salvatore ^a,c  

^a UNIVERSITY OF VERONA   (Italy)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c Section of Clinical Neurology   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; BRAIN; CORRELATION METHODS; NEUROLOGY; PROTEINS; SOLUBILITY; TISSUE;

DEGLYOSYLATION; EXOGENOUS PROTEOLYSIS; PHENOTYPES;

DISEASES;

AMINO ACID; AMYLOID; ANTIBODY; C1 PRP C PROTEIN; ISOPROTEIN; METHIONINE; PEPTIDE; PRION PROTEIN; PRION PROTEIN ANTIBODY; PRION PROTEIN SC; PROTEIN; PRP 16 17 PROTEIN; PRP 17.5 18 PROTEIN; UNCLASSIFIED DRUG; UNGLYCOSYLATED PEPTIDE 19; UNGLYCOSYLATED PEPTIDE 21; VALINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; BRAIN HOMOGENATE; CARBOXY TERMINAL SEQUENCE; CLINICAL ARTICLE; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DEGLYCOSYLATION; FEMALE; GLYCOSYLATION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; MALE; NEUROLOGIC DISEASE; PEPTIDE MAPPING; PHENOTYPE; PRESCHOOL CHILD; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DEGRADATION; SCRAPIE; SENILE PLAQUE; TISSUE SLICE;

ADULT; AGED; BINDING SITES; BLOTTING, WESTERN; BRAIN; CREUTZFELDT-JAKOB SYNDROME; DETERGENTS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; GLYCOSYLATION; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; ISOELECTRIC FOCUSING; MALE; MIDDLE AGED; MUTATION; PEPTIDES; PHENOTYPE; PRIONS; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; PRPSC PROTEINS;

BOVINAE;

EID: 4644259154     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405468200     Document Type: Article

References (28)

1. Prusiner, S. B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13363-13383
2. Prusiner, S. B. (1997) Science 278, 245-251
3. Casalone, C., Zanusso, G., Acutis, P., Ferrari, S., Capucci, L., Tagliavini, F., Monaco, S., and Caramelli, M. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 3065-3070
4. Prusiner, S. B. (1992) Biochemistry 31, 12277-12288
5. McKinley, M. P., Meyer, R. K., Kenaga, L., Rahbar, F., Cotter, R., Serban, A., and Prusiner, S. B. (1991) J. Virol. 65, 1340-1351
6. Chen, S. G., Teplow, D. B., Parchi, P., Teller, J. K., Gambetti, P., and Autilio-Gambetti, L. (1995) J. Biol. Chem. 270, 19173-19180
7. Jimenez-Huete, A., Lievens, P. M., Vidal, R., Piccardo, P., Ghetti, B., Tagliavini, F., Frangione, B., and Prelli, F. (1998) Am. J. Pathol. 153, 1561-1572
8. Satoh, K., Muramoto, T., Tanaka, T., Kitamoto, N., Ironside, J. W., Nagashima, K., Yamada, M., Sato, T., Mohri, S., and Kitamoto, T. (2003) J. Gen. Virol. 84, 2885-2893
9. Zou, W. Q., Capellari, S., Parchi, P., Sy, M. S., Gambetti, P., and Chen, S. G. (2003) J. Biol. Chem. 278, 40429-40436
10. DeArmond, S. J., and Ironside, J. W. (1999) in Neuropathology of Prion Diseases (Prusiner, S. B., ed) pp. 585-652, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
11. Prusiner, S. B. (2001) N. Engl. J. Med. 344, 1516-1526
12. Collins, S., Boyd, A., Fletcher, A., Kaldor, J., Hill, A., Farish, S., McLean, C., Ansari, Z., Smith, M., and Masters, C. L. (2002) Ann. Neurol. 52, 115-118
13. Glatzel, M., Rogivue, C., Ghani, A., Streffer, J. R., Amsler, L., and Aguzzi, A. (2002) Lancet 360, 139-141
14. Parchi, P., Castellani, R., Capellari, S., Ghetti, B., Young, K., Chen, S. G., Farlow, M., Dickson, D. W., Sima, A. A., Trojanowski, J. Q., Petersen, R. B., and Gambetti, P. (1996) Ann. Neurol. 39, 767-778
15. Hill, A. F., Joiner, S., Wadsworth, J. D., Sidle, K. C., Bell, J. E., Budka, H., Ironside, J. W., and Collinge, J. (2003) Brain 126, 1333-1346
16. Zanusso, G., Ferrari, S., Cardone, F., Zampieri, P., Gelati, M., Fiorini, M., Farinazzo, A., Gardunan, M., Cavallaro, T., Bentivoglio, M., Righetti, P. G., Pocchiari, M., Rizzuto, N., and Monaco, S. (2003) N. Engl. J. Med. 348, 711-719
17. Zanusso, G., Righetti, P. G., Ferrari, S., Terrin, L., Farinazzo, A., Cardone, F., Pocchiari, M., Rizzuto, N., and Monaco, S. (2002) Electrophoresis 23, 347-355
18. Zanusso, G., Farinazzo, A., Fiorini, M., Gelati, M., Castagna, A., Righetti, P. G., Rizzuto, N., and Monaco, S. (2001) J. Biol. Chem. 276, 40377-40380
19. Wadsworth, J. D., Hill, A. F., Joiner, S., Jackson, G. S., Clarke, A. R., and Collinge, J. (1999) Nat. Cell Biol. 1, 55-59
20. Parchi, P., Giese, A., Capellari, S., Brown, P., Schulz-Schaeffer, W., Windl, O., Zerr, I., Budka, H., Kopp, N., Piccardo, P., Poser, S., Rojiani, A., Streichemberger, N., Julien, J., Vital, C., Ghetti, B., Gambetti, P., and Kretzschmar, H. (1999) Ann. Neurol. 46, 224-233
21. Parchi, P., Zou, W., Wang, W., Brown, P., Capellari, S., Ghetti, B., Kopp, N., Schulz-Schaeffer, W. J., Kretzschmar, H. A., Head, M. W., Ironside, J. W., Gambetti, P., and Chen, S. G. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 10168-10172
22. Pan, T., Colucci, M., Wong, B. S., Li, R., Liu, T., Petersen, R. B., Chen, S., Gambetti, P., and Sy, M. S. (2001) J. Biol. Chem. 276, 37284-37288
23. Korth, C., Kaneko, K., Groth, D., Heye, N., Telling, G., Mastrianni, J., Parchi, P., Gambetti, P., Will, R., Ironside, J., Heinrich, C., Tremblay, P., DeArmond, S. J., and Prusiner, S. B. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 4784-4789
24. Lawson, V. A., Priola, S. A., Meade-White, K., Lawson, M., and Chesebro, B. (2004) J. Biol. Chem. 279, 13689-13695
25. Tagliavini, F., Prelli, F., Ghiso, J., Bugiani, O., Serban, D., Prusiner, S. B., Farlow, M. R., Ghetti, B., and Frangione, B. (1991) EMBO J. 10, 513-519
26. Capellari, S., Parchi, P., Russo, C. M., Sanford, J., Sy, M. S., Gambetti, P., and Petersen, R. B. (2000) Am. J. Pathol. 157, 613-622
27. Forloni, G., Angeretti, N., Chiesa, R., Monzani, E., Salmona, M., Bugiani, O., and Tagliavini, F. (1993) Nature 362, 543-546
28. Daniels, M., Cereghetti, G. M., and Brown, D. R. (2001) Eur. J. Biochem. 268, 6155-6164