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Volumn 11, Issue 3, 2007, Pages 108-113

The proteins and the mechanisms of apoptosis: A mini-review of the fundamentals

Author keywords

Apoptosis; Protein

Indexed keywords

AMYLOID BETA PROTEIN; CASPASE; HEAT SHOCK PROTEIN; MEMBRANE PROTEIN; NEURONAL THREAD PROTEIN AD7C; PROTEIN BCL 2; UNCLASSIFIED DRUG;

EID: 34547206149     PISSN: 11084189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (71)

References (46)
  • 1
    • 0036899079 scopus 로고    scopus 로고
    • Apoptosomes: Engines for caspase activation
    • Adams JM, Cory S. Apoptosomes: engines for caspase activation. Curr Opin Cell Biol 2002;14:715-720
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 715-720
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams JM, Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 1998;281(5381):1322-1326
    • (1998) Science , vol.281 , Issue.5381 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 3
    • 0035369143 scopus 로고    scopus 로고
    • The mitochondrial apoptosome: A killer unleashed by the cytochrome seas
    • Adrain C, Martin SJ. The mitochondrial apoptosome: a killer unleashed by the cytochrome seas. Trends Biochem Sci 2001; 26:390-397
    • (2001) Trends Biochem Sci , vol.26 , pp. 390-397
    • Adrain, C.1    Martin, S.J.2
  • 4
    • 0034253533 scopus 로고    scopus 로고
    • Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
    • Beere HM, Wolf BB, Cain K, et al. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat. Cell Biol 2000; 2: 469-475
    • (2000) Nat. Cell Biol , vol.2 , pp. 469-475
    • Beere, H.M.1    Wolf, B.B.2    Cain, K.3
  • 5
    • 0033062724 scopus 로고    scopus 로고
    • Boonman Z, Isacson O. Apoptosis in neuronal development and transplantation: role of caspases and trophic factors. Exp Neurol 1999; 156:1-15
    • Boonman Z, Isacson O. Apoptosis in neuronal development and transplantation: role of caspases and trophic factors. Exp Neurol 1999; 156:1-15
  • 6
    • 0344925540 scopus 로고    scopus 로고
    • Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
    • Chipuk JE, Maurer U, Green DR, Schuler M. Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription. Cancer Cell 2003; 4: 371-381
    • (2003) Cancer Cell , vol.4 , pp. 371-381
    • Chipuk, J.E.1    Maurer, U.2    Green, D.R.3    Schuler, M.4
  • 7
    • 0033545382 scopus 로고    scopus 로고
    • Bcl-2 regulates amplification of caspase activation by cytochrome c
    • Cosulich SC, Savory PJ, Clarke PR. Bcl-2 regulates amplification of caspase activation by cytochrome c. Curr. Biol 1999; 9:147-150
    • (1999) Curr. Biol , vol.9 , pp. 147-150
    • Cosulich, S.C.1    Savory, P.J.2    Clarke, P.R.3
  • 8
    • 0035213498 scopus 로고    scopus 로고
    • Caspases: Cellular demolition experts
    • Creagh EM, Martin SJ. Caspases: cellular demolition experts. Biochem Soc Trans 2001; 29 (Pt 6):696-702
    • (2001) Biochem Soc Trans , vol.29 , Issue.PART 6 , pp. 696-702
    • Creagh, E.M.1    Martin, S.J.2
  • 10
    • 0035113832 scopus 로고    scopus 로고
    • Alzheimer-associated neuronal thread protein-induced apoptosis and impaired mitochondrial function in human central nervous system-derived neuronal cells
    • de la Monte SM, Wands JR. Alzheimer-associated neuronal thread protein-induced apoptosis and impaired mitochondrial function in human central nervous system-derived neuronal cells. J Neuropathol Exp Neurol 2001; 60: 195-207
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 195-207
    • de la Monte, S.M.1    Wands, J.R.2
  • 11
    • 0033590083 scopus 로고    scopus 로고
    • Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression
    • Fadeel B, Gleiss B, Hogstrand K, et al. Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression. Biochem Biophys Res Commun 1999; 266: 504-511
    • (1999) Biochem Biophys Res Commun , vol.266 , pp. 504-511
    • Fadeel, B.1    Gleiss, B.2    Hogstrand, K.3
  • 12
    • 34547158932 scopus 로고    scopus 로고
    • Distinct pathways regulate proapoptotic nix and BNip3 in cardiac stress
    • Nov 16; [Epub ahead of print
    • Galvez AS, Brunskill EW, Marreez Y, et al. Distinct pathways regulate proapoptotic nix and BNip3 in cardiac stress. J Biol Chem. 2005 Nov 16; [Epub ahead of print]
    • (2005) J Biol Chem
    • Galvez, A.S.1    Brunskill, E.W.2    Marreez, Y.3
  • 13
    • 0345549456 scopus 로고    scopus 로고
    • Specific interaction of the antiapoptotic protein Nr-13 with phospholipid monolayers is prevented by the BH3 domain of Bax
    • Girard-Egrot A, Chauvet JP, Gillet G and Moradi-Ameli M. Specific interaction of the antiapoptotic protein Nr-13 with phospholipid monolayers is prevented by the BH3 domain of Bax. J Mol Biol 2004;335:321-331
    • (2004) J Mol Biol , vol.335 , pp. 321-331
    • Girard-Egrot, A.1    Chauvet, J.P.2    Gillet, G.3    Moradi-Ameli, M.4
  • 14
    • 84915943405 scopus 로고
    • Cell death in normal vertebrate ontogeny
    • Gluecksmann A. Cell death in normal vertebrate ontogeny. Biological Reviews 1951; 26: 59-86
    • (1951) Biological Reviews , vol.26 , pp. 59-86
    • Gluecksmann, A.1
  • 15
    • 0026582702 scopus 로고
    • Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
    • Hengartner MO, Ellis RE, Horvitz HR. Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature 1992;356(6369):494-499
    • (1992) Nature , vol.356 , Issue.6369 , pp. 494-499
    • Hengartner, M.O.1    Ellis, R.E.2    Horvitz, H.R.3
  • 16
    • 0033119367 scopus 로고    scopus 로고
    • Genetic control of programmed cell death in the nematode Caenorhabditis elegans
    • s
    • Horvitz HR. Genetic control of programmed cell death in the nematode Caenorhabditis elegans. Cancer Res 1999;59(7 Suppl):1701s-1706s
    • (1999) Cancer Res , vol.59 , Issue.7 SUPPL.
    • Horvitz, H.R.1
  • 17
    • 20544437817 scopus 로고    scopus 로고
    • Unknotting the roles of Bcl-2 and Bcl-xL in cell death
    • Kim R. Unknotting the roles of Bcl-2 and Bcl-xL in cell death. Biochem Biophys Res Commun 2005; 333:336-343
    • (2005) Biochem Biophys Res Commun , vol.333 , pp. 336-343
    • Kim, R.1
  • 18
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR and Newmeyer DD. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997; 275:1132-1136
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 20
    • 0029972806 scopus 로고    scopus 로고
    • Ko LJ and Prives C. p53: puzzle and paradigm. Genes Dev 1996; 10:1054-1072
    • Ko LJ and Prives C. p53: puzzle and paradigm. Genes Dev 1996; 10:1054-1072
  • 22
    • 0035433420 scopus 로고    scopus 로고
    • Four deaths and a funeral: From caspases to alternative mechanisms
    • Leist M, Jaattela M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001; 2: 589-598
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 589-598
    • Leist, M.1    Jaattela, M.2
  • 23
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88:323-331
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 25
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu X, Kim CN, Yang J, Jemmerson R and Wang X. Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 1996;86:147-157
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 26
    • 0035409448 scopus 로고    scopus 로고
    • Programmed cell death and apoptosis: Origins of the theory.Nat Rev
    • Lockshin RA, Zakeri Z. Programmed cell death and apoptosis: origins of the theory.Nat Rev Mol Cell Biol 2001; 2: 545-550
    • (2001) Mol Cell Biol , vol.2 , pp. 545-550
    • Lockshin, R.A.1    Zakeri, Z.2
  • 27
    • 0037057629 scopus 로고    scopus 로고
    • Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
    • Marsden VS, O'Connor L, O'Reilly LA, et al. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature. 2002;419(6907):634-637
    • (2002) Nature , vol.419 , Issue.6907 , pp. 634-637
    • Marsden, V.S.1    O'Connor, L.2    O'Reilly, L.A.3
  • 28
    • 0037349289 scopus 로고    scopus 로고
    • p53 has a direct apoptogenic role at the mitochondria
    • Mihara M, Erster S, Zaika A, et al. p53 has a direct apoptogenic role at the mitochondria. Mol Cell 2003; 11: 577-590
    • (2003) Mol Cell , vol.11 , pp. 577-590
    • Mihara, M.1    Erster, S.2    Zaika, A.3
  • 29
    • 17444413787 scopus 로고    scopus 로고
    • Amyloid-B peptide triggers Fas-independent apoptosis and differentiation of neural progenitor cells
    • Millet P, Lages CS, Hark S, et al. Amyloid-B peptide triggers Fas-independent apoptosis and differentiation of neural progenitor cells. Neurobiology of Disease 2005;19: 57-65
    • (2005) Neurobiology of Disease , vol.19 , pp. 57-65
    • Millet, P.1    Lages, C.S.2    Hark, S.3
  • 30
    • 4644246284 scopus 로고    scopus 로고
    • Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons
    • Mori M, Burgess DL, Gefrides LA, et al. Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons. Cell Death Differ 2004;11:1223-1233
    • (2004) Cell Death Differ , vol.11 , pp. 1223-1233
    • Mori, M.1    Burgess, D.L.2    Gefrides, L.A.3
  • 31
    • 0037390872 scopus 로고    scopus 로고
    • A novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum
    • Mund T, Gewies A, Schoenfeld N, Bauer MK, Grimm S. Spike. A novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum. FASEB J 2003;17:696-698
    • (2003) FASEB J , vol.17 , pp. 696-698
    • Mund, T.1    Gewies, A.2    Schoenfeld, N.3    Bauer, M.K.4    Grimm, S.5    Spike6
  • 32
    • 0036143720 scopus 로고    scopus 로고
    • Hsp27 as a Negative Regulator of Cytochrome c Release
    • Paul C, Manero F, Gonin S, et al. Hsp27 as a Negative Regulator of Cytochrome c Release. Mol Cell Biol 2002; 22: 816-834
    • (2002) Mol Cell Biol , vol.22 , pp. 816-834
    • Paul, C.1    Manero, F.2    Gonin, S.3
  • 33
    • 4544298249 scopus 로고    scopus 로고
    • Mitochondrial mechanisms of neural cell apoptosis
    • Polster BM and Fiskum G. Mitochondrial mechanisms of neural cell apoptosis. J Neurochem 2004; 90:1281-1289
    • (2004) J Neurochem , vol.90 , pp. 1281-1289
    • Polster, B.M.1    Fiskum, G.2
  • 34
    • 0036644078 scopus 로고    scopus 로고
    • Death to flies: Drosophila as a model system to study programmed cell death
    • Richardson H and Kumar S. Death to flies: Drosophila as a model system to study programmed cell death. J Immunol Methods 2002;265:21-38
    • (2002) J Immunol Methods , vol.265 , pp. 21-38
    • Richardson, H.1    Kumar, S.2
  • 35
    • 0033957359 scopus 로고    scopus 로고
    • Morphologic, biochemical hallmarks of apoptosis
    • Saraste A and Pulkki K. Morphologic, biochemical hallmarks of apoptosis. Cardiovasc Res 2000; 3: 528-537
    • (2000) Cardiovasc Res , vol.3 , pp. 528-537
    • Saraste, A.1    Pulkki, K.2
  • 36
    • 0038751860 scopus 로고    scopus 로고
    • p53 downstream targets, chemosensitivity
    • Sax J K and El Deiry W S. p53 downstream targets, chemosensitivity. Cell Death Differ 2003; 10: 413-417
    • (2003) Cell Death Differ , vol.10 , pp. 413-417
    • Sax, J.K.1    El Deiry, W.S.2
  • 37
    • 0031762952 scopus 로고    scopus 로고
    • Trophic support promotes survival of bcl-x-deficient telencephalic cells in vitro
    • Shindler KS, Yunker AM, Cahn R, et al. Trophic support promotes survival of bcl-x-deficient telencephalic cells in vitro. Cell Death Diff 1998; 5: 901-910
    • (1998) Cell Death Diff , vol.5 , pp. 901-910
    • Shindler, K.S.1    Yunker, A.M.2    Cahn, R.3
  • 38
    • 0033601746 scopus 로고    scopus 로고
    • Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
    • Slee EA, Harte MT, Kluck RM, et al. Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J. Cell Biol 1999; 144: 281-292
    • (1999) J. Cell Biol , vol.144 , pp. 281-292
    • Slee, E.A.1    Harte, M.T.2    Kluck, R.M.3
  • 39
    • 0033521537 scopus 로고    scopus 로고
    • Song Q, Kuang Y, Dixit VM, Vincenz C. Boo, a novel negative regulator of cell death, interacts with Apaf-1. EMBO J 1999; 18:167-178
    • Song Q, Kuang Y, Dixit VM, Vincenz C. Boo, a novel negative regulator of cell death, interacts with Apaf-1. EMBO J 1999; 18:167-178
  • 40
    • 33244474580 scopus 로고    scopus 로고
    • Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation.J
    • Stankiewicz AR, Lachapelle G, Foo CP, et al. Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation.J Biol Chem 2005; 280:38729-38739
    • (2005) Biol Chem , vol.280 , pp. 38729-38739
    • Stankiewicz, A.R.1    Lachapelle, G.2    Foo, C.P.3
  • 41
    • 0034676455 scopus 로고    scopus 로고
    • Surfing the p53 network
    • Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature. 2000;408(6810):307-310
    • (2000) Nature , vol.408 , Issue.6810 , pp. 307-310
    • Vogelstein, B.1    Lane, D.2    Levine, A.J.3
  • 42
    • 0035803554 scopus 로고    scopus 로고
    • Essential Role of the Prosurvival bcl-2 Homologue A1 in Mast Cell Survival After Allergic Activation
    • Xiang Z, Ahmed AA, Mφller C, et al. Essential Role of the Prosurvival bcl-2 Homologue A1 in Mast Cell Survival After Allergic Activation. The Journal of Experimental Medicine 2001;194:1561-1570
    • (2001) The Journal of Experimental Medicine , vol.194 , pp. 1561-1570
    • Xiang, Z.1    Ahmed, A.A.2    Mφller, C.3
  • 43
    • 3142652618 scopus 로고    scopus 로고
    • BOK and NOXA are essential mediators of p53-dependent apoptosis
    • Yakovlev AG, Di Giovanni S, Wang G, et al. BOK and NOXA are essential mediators of p53-dependent apoptosis. J Biol Chem 2004; 279:28367-28374
    • (2004) J Biol Chem , vol.279 , pp. 28367-28374
    • Yakovlev, A.G.1    Di Giovanni, S.2    Wang, G.3
  • 44
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • Yang J, Liu X, Bhalla K, Kim CN, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 1997; 275:1129-1132
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4
  • 45
    • 0025255636 scopus 로고
    • The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death
    • Yuan J, Horvitz HR. The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev Biol 1991;38:33-41
    • (1991) Dev Biol , vol.38 , pp. 33-41
    • Yuan, J.1    Horvitz, H.R.2
  • 46
    • 0033231548 scopus 로고    scopus 로고
    • HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis
    • Zhou L, Song Z, Tittel J, Steller H. HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis. Mol Cell 1999;4:745-755
    • (1999) Mol Cell , vol.4 , pp. 745-755
    • Zhou, L.1    Song, Z.2    Tittel, J.3    Steller, H.4


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