-
1
-
-
3442886811
-
The pathophysiology of mitochondrial cell death
-
D.R. Green, and G. Kroemer The pathophysiology of mitochondrial cell death Science 305 2004 626 629
-
(2004)
Science
, vol.305
, pp. 626-629
-
-
Green, D.R.1
Kroemer, G.2
-
2
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
X. Liu, C.N. Kim, J. Yang, R. Jemmerson, and X. Wang Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c Cell 86 1996 147 157
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
3
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
C. Du, M. Fang, Y. Li, L. Li, and X. Wang Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition Cell 102 2000 33 42
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
4
-
-
18544386724
-
Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
-
R. Hegde, S.M. Srinivasula, Z. Zhang, R. Wassell, R. Mukattash, L. Cilenti, G. DuBois, Y. Lazebnik, A.S. Zervos, T. Fernandes-Alnemri, and E.S. Alnemri Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction J. Biol. Chem. 277 2002 432 438
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 432-438
-
-
Hegde, R.1
Srinivasula, S.M.2
Zhang, Z.3
Wassell, R.4
Mukattash, R.5
Cilenti, L.6
Dubois, G.7
Lazebnik, Y.8
Zervos, A.S.9
Fernandes-Alnemri, T.10
Alnemri, E.S.11
-
5
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
S.A. Susin, H.K. Lorenzo, N. Zamzami, I. Marzo, B.E. Snow, G.M. Brothers, J. Mangion, E. Jacotot, P. Costantini, M. Loeffler, N. Larochette, D.R. Goodlett, R. Aebersold, D.P. Siderovski, J.M. Penninger, and G. Kroemer Molecular characterization of mitochondrial apoptosis-inducing factor Nature 397 1999 441 446
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, N.11
Goodlett, D.R.12
Aebersold, R.13
Siderovski, D.P.14
Penninger, J.M.15
Kroemer, G.16
-
6
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
L.Y. Li, X. Luo, and X. Wang Endonuclease G is an apoptotic DNase when released from mitochondria Nature 412 2001 95 99
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
7
-
-
16844377506
-
Recent advances in understanding the cell death pathways activated by anticancer therapy
-
R. Kim Recent advances in understanding the cell death pathways activated by anticancer therapy Cancer 103 2005 1551 1560
-
(2005)
Cancer
, vol.103
, pp. 1551-1560
-
-
Kim, R.1
-
8
-
-
2442460088
-
Role of mitochondrial membrane permeabilization in apoptosis and cancer
-
J. Henry-Mowatt, C. Dive, J.C. Martinou, and D. James Role of mitochondrial membrane permeabilization in apoptosis and cancer Oncogene 23 2004 2850 2860
-
(2004)
Oncogene
, vol.23
, pp. 2850-2860
-
-
Henry-Mowatt, J.1
Dive, C.2
Martinou, J.C.3
James, D.4
-
10
-
-
1542357606
-
Apoptosis pathways in cancer and cancer therapy
-
K.M. Debatin Apoptosis pathways in cancer and cancer therapy Cancer Immunol. Immunother. 53 2004 153 159
-
(2004)
Cancer Immunol. Immunother.
, vol.53
, pp. 153-159
-
-
Debatin, K.M.1
-
11
-
-
16844386555
-
Bid mediates apoptotic synergy between TNF-related apoptosis-inducing ligand (TRAIL) and DNA damage
-
V.C. Broaddus, T.B. Dansen, K.S. Abayasiriwardana, S.M. Wilson, A.J. Finch, L.B. Swigart, A.E. Hunt, and G.I. Evan Bid mediates apoptotic synergy between TNF-related apoptosis-inducing ligand (TRAIL) and DNA damage J. Biol. Chem. 280 2005 12486 12493
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12486-12493
-
-
Broaddus, V.C.1
Dansen, T.B.2
Abayasiriwardana, K.S.3
Wilson, S.M.4
Finch, A.J.5
Swigart, L.B.6
Hunt, A.E.7
Evan, G.I.8
-
12
-
-
2442661614
-
Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation
-
M. Heinrich, J. Neumeyer, M. Jakob, C. Hallas, V. Tchikov, S. Winoto-Morbach, M. Wickel, W. Schneider-Brachert, A. Trauzold, A. Hethke, and S. Schutze Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation Cell Death Differ. 11 2004 550 563
-
(2004)
Cell Death Differ.
, vol.11
, pp. 550-563
-
-
Heinrich, M.1
Neumeyer, J.2
Jakob, M.3
Hallas, C.4
Tchikov, V.5
Winoto-Morbach, S.6
Wickel, M.7
Schneider-Brachert, W.8
Trauzold, A.9
Hethke, A.10
Schutze, S.11
-
13
-
-
20044381271
-
A central role for Bid in granzyme B-induced apoptosis
-
N.J. Waterhouse, K.A. Sedelies, K.A. Browne, M.E. Wowk, A. Newbold, V.R. Sutton, C.J. Clarke, J. Oliaro, R.K. Lindemann, P.I. Bird, R.W. Johnstone, and J.A. Trapani A central role for Bid in granzyme B-induced apoptosis J. Biol. Chem. 280 2005 4476 4482
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4476-4482
-
-
Waterhouse, N.J.1
Sedelies, K.A.2
Browne, K.A.3
Wowk, M.E.4
Newbold, A.5
Sutton, V.R.6
Clarke, C.J.7
Oliaro, J.8
Lindemann, R.K.9
Bird, P.I.10
Johnstone, R.W.11
Trapani, J.A.12
-
14
-
-
14644437742
-
Mechanisms of resistance to TRAIL-induced apoptosis in cancer
-
L. Zhang, and B. Fang Mechanisms of resistance to TRAIL-induced apoptosis in cancer Cancer Gene Ther. 12 2005 228 237
-
(2005)
Cancer Gene Ther.
, vol.12
, pp. 228-237
-
-
Zhang, L.1
Fang, B.2
-
15
-
-
4544334411
-
Involvement of reactive oxygen species (ROS) in the induction of genetic instability by radiation
-
H. Tominaga, S. Kodama, N. Matsuda, K. Suzuki, and M. Watanabe Involvement of reactive oxygen species (ROS) in the induction of genetic instability by radiation J. Radiat. Res. (Tokyo) 45 2004 181 188
-
(2004)
J. Radiat. Res. (Tokyo)
, vol.45
, pp. 181-188
-
-
Tominaga, H.1
Kodama, S.2
Matsuda, N.3
Suzuki, K.4
Watanabe, M.5
-
16
-
-
0344825072
-
DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation
-
H.L. Huang, L.W. Fang, S.P. Lu, C.K. Chou, T.Y. Luh, and M.Z. Lai DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation Oncogene 22 2003 8168 8177
-
(2003)
Oncogene
, vol.22
, pp. 8168-8177
-
-
Huang, H.L.1
Fang, L.W.2
Lu, S.P.3
Chou, C.K.4
Luh, T.Y.5
Lai, M.Z.6
-
17
-
-
3242804373
-
Inhibition of mitochondrial bioenergetics: The effects on structure of mitochondria in the cell and on apoptosis
-
K.G. Lyamzaev, D.S. Izyumov, A.V. Avetisyan, F. Yang, O.Y. Pletjushkina, and B.V. Chernyak Inhibition of mitochondrial bioenergetics: the effects on structure of mitochondria in the cell and on apoptosis Acta Biochim. Pol. 51 2004 553 562
-
(2004)
Acta Biochim. Pol.
, vol.51
, pp. 553-562
-
-
Lyamzaev, K.G.1
Izyumov, D.S.2
Avetisyan, A.V.3
Yang, F.4
Pletjushkina, O.Y.5
Chernyak, B.V.6
-
18
-
-
1842865745
-
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
-
T. Kanzawa, I.M. Germano, T. Komata, H. Ito, Y. Kondo, and S. Kondo Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells Cell Death Differ. 11 2004 448 457
-
(2004)
Cell Death Differ.
, vol.11
, pp. 448-457
-
-
Kanzawa, T.1
Germano, I.M.2
Komata, T.3
Ito, H.4
Kondo, Y.5
Kondo, S.6
-
19
-
-
0037464353
-
Functional screening of genes suppressing TRAIL-induced apoptosis: Distinct inhibitory activities of Bcl-XL and Bcl-2
-
I.K. Kim, Y.K. Jung, D.Y. Noh, Y.S. Song, C.H. Choi, B.H. Oh, E.S. Masuda, and Y.K. Jung Functional screening of genes suppressing TRAIL-induced apoptosis: distinct inhibitory activities of Bcl-XL and Bcl-2 Br. J. Cancer 88 2003 910 917
-
(2003)
Br. J. Cancer
, vol.88
, pp. 910-917
-
-
Kim, I.K.1
Jung, Y.K.2
Noh, D.Y.3
Song, Y.S.4
Choi, C.H.5
Oh, B.H.6
Masuda, E.S.7
Jung, Y.K.8
-
20
-
-
0034655373
-
Apoptosis or senescence-like growth arrest: Influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts
-
Q.M. Chen, J. Liu, and J.B. Merrett Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts Biochem. J. 347 2000 543 551
-
(2000)
Biochem. J.
, vol.347
, pp. 543-551
-
-
Chen, Q.M.1
Liu, J.2
Merrett, J.B.3
-
21
-
-
0038013875
-
Senescence, apoptosis and therapy-cutting the lifelines of cancer
-
C.A. Schmitt Senescence, apoptosis and therapy-cutting the lifelines of cancer Nat. Rev. Cancer 3 2003 286 295
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 286-295
-
-
Schmitt, C.A.1
-
22
-
-
0033580219
-
Bcl-2 overexpression results in reciprocal downregulation of Bcl-X(L) and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosis
-
E.L. Arriola, A.M. Rodriguez-Lopez, J.A. Hickman, and C.M. Chresta Bcl-2 overexpression results in reciprocal downregulation of Bcl-X(L) and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosis Oncogene 18 1999 1457 1464
-
(1999)
Oncogene
, vol.18
, pp. 1457-1464
-
-
Arriola, E.L.1
Rodriguez-Lopez, A.M.2
Hickman, J.A.3
Chresta, C.M.4
-
23
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
-
S. Shimizu, T. Kanaseki, N. Mizushima, T. Mizuta, S. Arakawa-Kobayashi, C.B. Thompson, and Y. Tsujimoto Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes Nat. Cell Biol. 6 2004 1221 1228
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
Thompson, C.B.6
Tsujimoto, Y.7
-
24
-
-
0036548511
-
The permeability transition pore signals apoptosis by directing Bax translocation and multimerization
-
F. De Giorgi, L. Lartigue, M.K. Bauer, A. Schubert, S. Grimm, G.T. Hanson, S.J. Remington, R.J. Youle, and F. Ichas The permeability transition pore signals apoptosis by directing Bax translocation and multimerization FASEB J. 16 2002 607 609
-
(2002)
FASEB J.
, vol.16
, pp. 607-609
-
-
De Giorgi, F.1
Lartigue, L.2
Bauer, M.K.3
Schubert, A.4
Grimm, S.5
Hanson, G.T.6
Remington, S.J.7
Youle, R.J.8
Ichas, F.9
-
25
-
-
0037279648
-
Apaf-1/cytochrome c apoptosome: An essential initiator of caspase activation or just a sideshow?
-
B. Baliga, and S. Kumar Apaf-1/cytochrome c apoptosome: an essential initiator of caspase activation or just a sideshow? Cell Death Differ. 10 2003 16 18
-
(2003)
Cell Death Differ.
, vol.10
, pp. 16-18
-
-
Baliga, B.1
Kumar, S.2
-
27
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
M. Muzio, A.M. Chinnaiyan, F.C. Kischkel, K. O'Rourke, A. Shevchenko, J. Ni, C. Scaffidi, J.D. Bretz, M. Zhang, R. Gentz, M. Mann, P.H. Krammer, M.E. Peter, and V.M. Dixit FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex Cell 85 1996 817 827
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
Mann, M.11
Krammer, P.H.12
Peter, M.E.13
Dixit, V.M.14
-
28
-
-
0141953270
-
A JNK-dependent pathway is required for TNFalpha-induced apoptosis
-
Y. Deng, X. Ren, L. Yang, Y. Lin, and X. Wu A JNK-dependent pathway is required for TNFalpha-induced apoptosis Cell 115 2003 61 70
-
(2003)
Cell
, vol.115
, pp. 61-70
-
-
Deng, Y.1
Ren, X.2
Yang, L.3
Lin, Y.4
Wu, X.5
-
29
-
-
0038382972
-
Nonredundant role of Bax and Bak in Bid-mediated apoptosis
-
P.F. Cartron, P. Juin, L. Oliver, S. Martin, K. Meflah, and F.M. Vallette Nonredundant role of Bax and Bak in Bid-mediated apoptosis Mol. Cell. Biol. 23 2003 4701 4712
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4701-4712
-
-
Cartron, P.F.1
Juin, P.2
Oliver, L.3
Martin, S.4
Meflah, K.5
Vallette, F.M.6
-
30
-
-
7244242456
-
Beta-actin is required for mitochondria clustering and ROS generation in TNF-induced, caspase-independent cell death
-
J. Li, Q. Li, C. Xie, H. Zhou, Y. Wang, N. Zhang, H. Shao, S.C. Chan, X. Peng, S.C. Lin, and J. Han Beta-actin is required for mitochondria clustering and ROS generation in TNF-induced, caspase-independent cell death J. Cell Sci. 117 2004 4673 4680
-
(2004)
J. Cell Sci.
, vol.117
, pp. 4673-4680
-
-
Li, J.1
Li, Q.2
Xie, C.3
Zhou, H.4
Wang, Y.5
Zhang, N.6
Shao, H.7
Chan, S.C.8
Peng, X.9
Lin, S.C.10
Han, J.11
-
31
-
-
0037235140
-
In AML cell lines Ara-C combined with purine analogues is able to exert synergistic as well as antagonistic effects on proliferation, apoptosis and disruption of mitochondrial membrane potential
-
K.U. Chow, S. Boehrer, S. Napieralski, D. Nowak, A. Knau, D. Hoelzer, P.S. Mitrou, and E. Weidmann In AML cell lines Ara-C combined with purine analogues is able to exert synergistic as well as antagonistic effects on proliferation, apoptosis and disruption of mitochondrial membrane potential Leuk. Lymphoma 44 2003 165 173
-
(2003)
Leuk. Lymphoma
, vol.44
, pp. 165-173
-
-
Chow, K.U.1
Boehrer, S.2
Napieralski, S.3
Nowak, D.4
Knau, A.5
Hoelzer, D.6
Mitrou, P.S.7
Weidmann, E.8
-
32
-
-
17644397025
-
Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kappaB
-
E. Pozo-Guisado, J.M. Merino, S. Mulero-Navarro, M.J. Lorenzo-Benayas, F. Centeno, A. Alvarez-Barrientos, and P.M. Salguero Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kappaB Int. J. Cancer 115 2005 74 84
-
(2005)
Int. J. Cancer
, vol.115
, pp. 74-84
-
-
Pozo-Guisado, E.1
Merino, J.M.2
Mulero-Navarro, S.3
Lorenzo-Benayas, M.J.4
Centeno, F.5
Alvarez-Barrientos, A.6
Salguero, P.M.7
-
33
-
-
0031754859
-
An oxidative stress-mediated death pathway in irradiated human leukemia cells mapped using multilaser flow cytometry
-
X. Sheng-Tanner, E.A. Bump, and D.W. Hedley An oxidative stress-mediated death pathway in irradiated human leukemia cells mapped using multilaser flow cytometry Radiat. Res. 150 1998 636 647
-
(1998)
Radiat. Res.
, vol.150
, pp. 636-647
-
-
Sheng-Tanner, X.1
Bump, E.A.2
Hedley, D.W.3
-
34
-
-
14844310312
-
Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells
-
N. Canu, R. Tufi, A.L. Serafino, G. Amadoro, M.T. Ciotti, and P. Calissano Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells J. Neurochem. 92 2005 1228 1242
-
(2005)
J. Neurochem.
, vol.92
, pp. 1228-1242
-
-
Canu, N.1
Tufi, R.2
Serafino, A.L.3
Amadoro, G.4
Ciotti, M.T.5
Calissano, P.6
-
35
-
-
17644378047
-
Role of p53 and reactive oxygen species in apoptotic response to copper and zinc in epithelial breast cancer cells
-
E.A. Ostrakhovitch, and M.G. Cherian Role of p53 and reactive oxygen species in apoptotic response to copper and zinc in epithelial breast cancer cells Apoptosis 10 2005 111 121
-
(2005)
Apoptosis
, vol.10
, pp. 111-121
-
-
Ostrakhovitch, E.A.1
Cherian, M.G.2
-
36
-
-
0036196425
-
Activation and caspase-mediated inhibition of PARP: A molecular switch between fibroblast necrosis and apoptosis in death receptor signaling
-
M. Los, M. Mozoluk, D. Ferrari, A. Stepczynska, C. Stroh, A. Renz, Z. Herceg, Z.Q. Wang, and K. Schulze-Osthoff Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling Mol. Biol. Cell 13 2002 978 988
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 978-988
-
-
Los, M.1
Mozoluk, M.2
Ferrari, D.3
Stepczynska, A.4
Stroh, C.5
Renz, A.6
Herceg, Z.7
Wang, Z.Q.8
Schulze-Osthoff, K.9
-
37
-
-
7744224359
-
Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases
-
D.G. Breckenridge, and D. Xue Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases Curr. Opin. Cell Biol. 16 2004 647 652
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 647-652
-
-
Breckenridge, D.G.1
Xue, D.2
-
38
-
-
10044272950
-
Bcl-XL disrupts death-inducing signal complex formation in plasma membrane induced by hypoxia/reoxygenation
-
X. Wang, J. Zhang, H.P. Kim, Y. Wang, A.M. Choi, and S.W. Ryter Bcl-XL disrupts death-inducing signal complex formation in plasma membrane induced by hypoxia/reoxygenation FASEB J. 18 2004 1826 1833
-
(2004)
FASEB J.
, vol.18
, pp. 1826-1833
-
-
Wang, X.1
Zhang, J.2
Kim, H.P.3
Wang, Y.4
Choi, A.M.5
Ryter, S.W.6
-
39
-
-
0034615860
-
Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis
-
S.A. Keogh, H. Walczak, L. Bouchier-Hayes, and S.J. Martin Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis FEBS Lett. 471 2000 93 98
-
(2000)
FEBS Lett.
, vol.471
, pp. 93-98
-
-
Keogh, S.A.1
Walczak, H.2
Bouchier-Hayes, L.3
Martin, S.J.4
-
40
-
-
9944257505
-
Alkylphosphocholine-induced glioma cell death is BCL-X(L)-sensitive, caspase-independent and characterized by massive cytoplasmic vacuole formation
-
U. Naumann, J. Wischhusen, S. Weit, J. Rieger, H. Wolburg, U. Massing, and M. Weller Alkylphosphocholine-induced glioma cell death is BCL-X(L)-sensitive, caspase-independent and characterized by massive cytoplasmic vacuole formation Cell Death Differ. 11 2004 1326 1341
-
(2004)
Cell Death Differ.
, vol.11
, pp. 1326-1341
-
-
Naumann, U.1
Wischhusen, J.2
Weit, S.3
Rieger, J.4
Wolburg, H.5
Massing, U.6
Weller, M.7
-
41
-
-
0033616709
-
Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis
-
R.K. Srivastava, Q.S. Mi, J.M. Hardwick, and D.L. Longo Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis Proc. Natl. Acad. Sci. USA 96 1999 3775 3780
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3775-3780
-
-
Srivastava, R.K.1
Mi, Q.S.2
Hardwick, J.M.3
Longo, D.L.4
-
42
-
-
0032504253
-
A potent cell death activity associated with transient high level expression of BCL-2
-
E.J. Uhlmann, T. Subramanian, C.A. Vater, R. Lutz, and G. Chinnadurai A potent cell death activity associated with transient high level expression of BCL-2 J. Biol. Chem. 273 1998 17926 17932
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17926-17932
-
-
Uhlmann, E.J.1
Subramanian, T.2
Vater, C.A.3
Lutz, R.4
Chinnadurai, G.5
-
43
-
-
0032055936
-
Bcl-2 and apoptosis in lymph node positive breast carcinoma
-
M.D. Berardo, R.M. Elledge, C. de Moor, G.M. Clark, C.K. Osborne, and D.C. Allred bcl-2 and apoptosis in lymph node positive breast carcinoma Cancer 82 1998 1296 1302
-
(1998)
Cancer
, vol.82
, pp. 1296-1302
-
-
Berardo, M.D.1
Elledge, R.M.2
De Moor, C.3
Clark, G.M.4
Osborne, C.K.5
Allred, D.C.6
-
44
-
-
0031706315
-
P53 and bcl-2 protein expression in non-small-cell lung carcinoma
-
P. Athanassiadou, T. Dosios, E. Petrakakou, A. Liossi, C. Zerva, and P. Athanassiades p53 and bcl-2 protein expression in non-small-cell lung carcinoma Diagn. Cytopathol. 19 1998 255 259
-
(1998)
Diagn. Cytopathol.
, vol.19
, pp. 255-259
-
-
Athanassiadou, P.1
Dosios, T.2
Petrakakou, E.3
Liossi, A.4
Zerva, C.5
Athanassiades, P.6
-
45
-
-
0021679848
-
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation
-
Y. Tsujimoto, L.R. Finger, J. Yunis, P.C. Nowell, and C.M. Croce Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation Science 226 1984 1097 1099
-
(1984)
Science
, vol.226
, pp. 1097-1099
-
-
Tsujimoto, Y.1
Finger, L.R.2
Yunis, J.3
Nowell, P.C.4
Croce, C.M.5
-
46
-
-
0035843156
-
Negative regulation of bcl-2 expression by p53 in hematopoietic cells
-
Y. Wu, J.W. Mehew, C.A. Heckman, M. Arcinas, and L.M. Boxer Negative regulation of bcl-2 expression by p53 in hematopoietic cells Oncogene 20 2001 240 251
-
(2001)
Oncogene
, vol.20
, pp. 240-251
-
-
Wu, Y.1
Mehew, J.W.2
Heckman, C.A.3
Arcinas, M.4
Boxer, L.M.5
-
47
-
-
0037428078
-
Parc: A cytoplasmic anchor for p53
-
A.Y. Nikolaev, M. Li, N. Puskas, J. Qin, and W. Gu Parc: a cytoplasmic anchor for p53 Cell 112 2003 29 40
-
(2003)
Cell
, vol.112
, pp. 29-40
-
-
Nikolaev, A.Y.1
Li, M.2
Puskas, N.3
Qin, J.4
Gu, W.5
-
48
-
-
0033965759
-
BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma
-
P.J. Beale, P. Rogers, F. Boxall, S.Y. Sharp, and L.R. Kelland BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma Br. J. Cancer 82 2000 436 440
-
(2000)
Br. J. Cancer
, vol.82
, pp. 436-440
-
-
Beale, P.J.1
Rogers, P.2
Boxall, F.3
Sharp, S.Y.4
Kelland, L.R.5
-
50
-
-
0036140941
-
Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2
-
Y. Liang, K.D. Nylander, C. Yan, and N.F. Schor Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2 Mol. Pharmacol. 61 2002 142 149
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 142-149
-
-
Liang, Y.1
Nylander, K.D.2
Yan, C.3
Schor, N.F.4
-
51
-
-
0033549248
-
Selective oxidation and externalization of membrane phosphatidylserine: Bcl-2-induced potentiation of the final common pathway for apoptosis
-
N.F. Schor, Y.Y. Tyurina, J.P. Fabisiak, V.A. Tyurin, J.S. Lazo, and V.E. Kagan Selective oxidation and externalization of membrane phosphatidylserine: Bcl-2-induced potentiation of the final common pathway for apoptosis Brain Res. 831 1999 125 130
-
(1999)
Brain Res.
, vol.831
, pp. 125-130
-
-
Schor, N.F.1
Tyurina, Y.Y.2
Fabisiak, J.P.3
Tyurin, V.A.4
Lazo, J.S.5
Kagan, V.E.6
-
52
-
-
13244279726
-
Possible role of NF-kappaB in Bcl-X(L) protection against hydrogen peroxide-induced PC12 cell death
-
J.H. Jang, and Y.J. Surh Possible role of NF-kappaB in Bcl-X(L) protection against hydrogen peroxide-induced PC12 cell death Redox Rep. 9 2004 343 348
-
(2004)
Redox Rep.
, vol.9
, pp. 343-348
-
-
Jang, J.H.1
Surh, Y.J.2
-
53
-
-
0034688306
-
Cell line dependence of Bcl-2-induced alteration of glutathione handling
-
N.F. Schor, C.M. Rudin, A.R. Hartman, C.B. Thompson, Y.Y. Tyurina, and V.E. Kagan Cell line dependence of Bcl-2-induced alteration of glutathione handling Oncogene 19 2000 472 476
-
(2000)
Oncogene
, vol.19
, pp. 472-476
-
-
Schor, N.F.1
Rudin, C.M.2
Hartman, A.R.3
Thompson, C.B.4
Tyurina, Y.Y.5
Kagan, V.E.6
-
54
-
-
0142231578
-
Bcl-2 activates a programme of premature senescence in human carcinoma cells
-
E. Crescenzi, G. Palumbo, and H.J. Brady Bcl-2 activates a programme of premature senescence in human carcinoma cells Biochem. J. 375 2003 263 274
-
(2003)
Biochem. J.
, vol.375
, pp. 263-274
-
-
Crescenzi, E.1
Palumbo, G.2
Brady, H.J.3
-
55
-
-
0034852080
-
Senescent cells are resistant to death despite low Bcl-2 level
-
M. Sasaki, T. Kumazaki, H. Takano, M. Nishiyama, and Y. Mitsui Senescent cells are resistant to death despite low Bcl-2 level Mech. Ageing Dev. 122 2001 1695 1706
-
(2001)
Mech. Ageing Dev.
, vol.122
, pp. 1695-1706
-
-
Sasaki, M.1
Kumazaki, T.2
Takano, H.3
Nishiyama, M.4
Mitsui, Y.5
-
56
-
-
0033603847
-
Effects of differential overexpression of Bcl-2 on apoptosis, proliferation, and telomerase activity in Jurkat T cells
-
V.L. Johnson, I.R. Cooper, J.R. Jenkins, and S.C. Chow Effects of differential overexpression of Bcl-2 on apoptosis, proliferation, and telomerase activity in Jurkat T cells Exp. Cell Res. 251 1999 175 184
-
(1999)
Exp. Cell Res.
, vol.251
, pp. 175-184
-
-
Johnson, V.L.1
Cooper, I.R.2
Jenkins, J.R.3
Chow, S.C.4
-
57
-
-
0038277105
-
Tumor cell senescence in cancer treatment
-
I.B. Roninson Tumor cell senescence in cancer treatment Cancer Res. 63 2003 2705 2715
-
(2003)
Cancer Res.
, vol.63
, pp. 2705-2715
-
-
Roninson, I.B.1
-
58
-
-
0037013154
-
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy
-
C.A. Schmitt, J.S. Fridman, M. Yang, S. Lee, E. Baranov, R.M. Hoffman, and S.W. Lowe A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy Cell 109 2002 335 346
-
(2002)
Cell
, vol.109
, pp. 335-346
-
-
Schmitt, C.A.1
Fridman, J.S.2
Yang, M.3
Lee, S.4
Baranov, E.5
Hoffman, R.M.6
Lowe, S.W.7
-
59
-
-
0345933237
-
Molecular requirements for the combined effects of TRAIL and ionising radiation
-
P. Marini, V. Jendrossek, E. Durand, C. Gruber, W. Budach, and C. Belka Molecular requirements for the combined effects of TRAIL and ionising radiation Radiother. Oncol. 68 2003 189 198
-
(2003)
Radiother. Oncol.
, vol.68
, pp. 189-198
-
-
Marini, P.1
Jendrossek, V.2
Durand, E.3
Gruber, C.4
Budach, W.5
Belka, C.6
-
60
-
-
0141869893
-
In vivo cooperation between Bcl-xL and the phosphoinositide 3-kinase-Akt signaling pathway for the protection of epidermal keratinocytes from apoptosis
-
J. Umeda, S. Sano, K. Kogawa, N. Motoyama, K. Yoshikawa, S. Itami, G. Kondoh, T. Watanabe, and J. Takeda In vivo cooperation between Bcl-xL and the phosphoinositide 3-kinase-Akt signaling pathway for the protection of epidermal keratinocytes from apoptosis FASEB J. 17 2003 610 620
-
(2003)
FASEB J.
, vol.17
, pp. 610-620
-
-
Umeda, J.1
Sano, S.2
Kogawa, K.3
Motoyama, N.4
Yoshikawa, K.5
Itami, S.6
Kondoh, G.7
Watanabe, T.8
Takeda, J.9
-
61
-
-
11144221007
-
Apoptotic and autophagic cell death induced by histone deacetylase inhibitors
-
Y. Shao, Z. Gao, P.A. Marks, and X. Jiang Apoptotic and autophagic cell death induced by histone deacetylase inhibitors Proc. Natl. Acad. Sci. USA 101 2004 18030 18035
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 18030-18035
-
-
Shao, Y.1
Gao, Z.2
Marks, P.A.3
Jiang, X.4
-
62
-
-
20544471104
-
Histone deacetylase inhibitors in programmed cell death and cancer therapy
-
P.A. Marks, and X. Jiang Histone deacetylase inhibitors in programmed cell death and cancer therapy Cell Cycle 4 2005
-
(2005)
Cell Cycle
, vol.4
-
-
Marks, P.A.1
Jiang, X.2
-
64
-
-
0141513738
-
Caspase-dependent and -independent panc-1 cell death due to actinomycin D and MK 886 are additive but increase clonogenic survival
-
K.M. Anderson, W. Alrefai, P. Bonomi, T.M. Seed, P. Dudeja, Y. Hu, and J.E. Harris Caspase-dependent and -independent panc-1 cell death due to actinomycin D and MK 886 are additive but increase clonogenic survival Exp. Biol. Med. (Maywood) 228 2003 915 925
-
(2003)
Exp. Biol. Med. (Maywood)
, vol.228
, pp. 915-925
-
-
Anderson, K.M.1
Alrefai, W.2
Bonomi, P.3
Seed, T.M.4
Dudeja, P.5
Hu, Y.6
Harris, J.E.7
-
65
-
-
2342465589
-
Regulation of the apoptosis-necrosis switch
-
P. Nicotera, and G. Melino Regulation of the apoptosis-necrosis switch Oncogene 23 2004 2757 2765
-
(2004)
Oncogene
, vol.23
, pp. 2757-2765
-
-
Nicotera, P.1
Melino, G.2
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