Active and Exo-site Inhibition of Human Factor Xa: Structure of des-Gla Factor Xa Inhibited by NAP5, a Potent Nematode Anticoagulant Protein from Ancylostoma caninum

Journal of Molecular Biology

Volumn 371, Issue 3, 2007, Pages 774-786

  Rios Steiner, Jorge L ^a   Murakami, Mário T ^b,c   Tulinsky, Alexander ^a   Arni, Raghuvir K ^b,c  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c CAT CEPID   (Brazil)

Author keywords

active and exo site binding; factor X Xa; ixolaris; nematode anticoagulant proteins; tissue factor pathway inhibitor

Indexed keywords

4 CARBOXYGLUTAMIC ACID; ANTICOAGULANT PROTEIN; BLOOD CLOTTING FACTOR 10; DISULFIDE; ELASTASE; NAP5 PROTEIN; TISSUE FACTOR PATHWAY INHIBITOR; UNCLASSIFIED DRUG;

ANCYLOSTOMA CANINUM; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DRUG INHIBITION; DRUG PROTEIN BINDING; DRUG STRUCTURE; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE;

ANCYLOSTOMA CANINUM; ANCYLOSTOMATOIDEA; MAMMALIA; NEMATODA;

EID: 34447640731     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.05.042     Document Type: Article

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