Bound structures of novel P3-Pi' β-strand mimetic inhibitors of thrombin

Journal of Medicinal Chemistry

Volumn 42, Issue 8, 1999, Pages 1376-1383

  St Charles, Robert ^a   Matthews, John H ^a   Zhang, Erli ^a   Tulinsky, A ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N [4 AMINO 5 (1,3 THIAZOL 2 YL) 5 OXOPENTYL] N' [(4 METHOXY 2,3 6 TRIMETHYLPHENYL)SULFONYL]GUANIDINE; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

ANTICOAGULATION; ARTICLE; BINDING AFFINITY; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME SPECIFICITY; STRUCTURE ANALYSIS;

AZA COMPOUNDS; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR MIMICRY; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; SERINE PROTEINASE INHIBITORS; THROMBIN;

EID: 0033594326     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980052n     Document Type: Article

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