Thrombomodulin-independent activation of protein C and specificity of hemostatically active snake venom serine proteinases: Crystal structures of native and inhibited Agkistrodon contortrix contortrix protein C activator

Journal of Biological Chemistry

Volumn 280, Issue 47, 2005, Pages 39309-39315

  Murakami, Mário T ^a   Arni, Raghuvir K ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CARBOHYDRATES; CATALYSIS; CRYSTAL STRUCTURE; ENZYMES; PHYSIOLOGY;

AGKISTRODON CONTORTRIX CONTORTRIX PROTEIN C ACTIVATOR; CATALYTIC SITES; SNAKE VENOM; STRUCTURAL CHANGES;

ENZYME KINETICS;

ACTIVATED PROTEIN C; ANION; BENZAMIDINE; BLOOD CLOTTING FACTOR 10A; CHLORIDE ION; PROTEIN C; SERINE PROTEINASE; SNAKE VENOM; SULFATE; THROMBIN; THROMBOMODULIN;

ALLOSTERISM; ANTICOAGULATION; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; HEMOSTASIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; THROMBOEMBOLISM; X RAY DIFFRACTION;

AGKISTRODON; ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ANCROD; ANIMALS; BENZAMIDINES; CATALYTIC DOMAIN; CROTALID VENOMS; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; HEMOSTASIS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN C; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SERINE PROTEINASE INHIBITORS; THROMBOMODULIN;

AGKISTRODON CONTORTRIX CONTORTRIX;

EID: 28244481846     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M508502200     Document Type: Article

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