In cultured astrocytes, p53 and MDM2 do not alter hypoxia-inducible factor-1α function regardless of the presence of DNA damage

Journal of Biological Chemistry

Volumn 282, Issue 22, 2007, Pages 16187-16201

  Rempe, David A ^a,c   Lelli, Katherine M ^a   Vangeison, Grace ^a   Johnson, Randall S ^b   Federoff, Howard J ^a  

^a Center for Aging and Developmental Biology   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CELL CULTURE; DISEASES; DNA; METABOLISM;

ASTROCYTES; ENDOGENOUS PROTEIN; HYPOXIA; TARGET EXPRESSION;

TRANSCRIPTION FACTORS;

HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN MDM2; PROTEIN P53; HIF1A PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ACIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CELL CULTURE; CELL DENSITY; CONTROLLED STUDY; DNA DAMAGE; HYPOXIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; ANIMAL; CELL HYPOXIA; COMPARATIVE STUDY; CYTOLOGY; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOUSE MUTANT; TRANSACTIVATION;

ACIDOSIS; ANIMALS; ASTROCYTES; CELL HYPOXIA; CELLS, CULTURED; DNA DAMAGE; GENE EXPRESSION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, MUTANT STRAINS; PROTO-ONCOGENE PROTEINS C-MDM2; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34447516987     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702203200     Document Type: Article

References (53)

1. Semenza, G. L. (2000) J. Appl. Physiol. 88, 1474-1480
2. Semenza, G. L. (2000) Genes Dev. 14, 1983-1991
3. Wenger, R. H. (2000) J. Exp. Biol. 203, 1253-1263
4. Kietzmann, T., Knabe, W., and Schmidt-Kastner, R. (2001) Eur. Arch. Psychiatry Clin. Neurosci. 251, 170-178
5. Bruick, R. K., and McKnight, S. L. (2001) Science 294, 1337-1340
6. Jaakkola, P., Mole, D. R., Tian, Y. M., Wilson, M. I., Gielbert, J., Gaskell, S. J., Kriegsheim, A., Hebestreit, H. F., Mukherji, M., Schofield, C. J., Maxwell, P. H., Pugh, C. W., and Ratcliffe, P. J. (2001) Science 292, 468-472
7. Yu, F., White, S. B., Zhao, Q., and Lee, F. S. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 9630-9635
8. Nishiyama, J., Manjeri, X., Venkatachalam, M., and Dong, Z. (2001) Biochem. J. 360, 49-56
9. Bruick, R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 9082-9087
10. An, W. G., Kanekal, M., Simon, M. C., Maltepe, E., Blagosklonny, M. V., and Neckers, L. M. (1998) Nature 392, 405-408
11. Hansson, L. O., Friedler, A., Freund, S., Rüdiger, S., and Fersht, A. R. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 10305-10309
12. Schmid, T., Zhou, J., and Brune, B. (2004) J. Cell Mol. Med. 8, 423-431
13. Kaluzova, M., Kaluz, S., Lerman, M. I., and Stanbridge, E. J. (2004) Mol. Cell. Biol. 24, 5757-5766
14. Ravi, R., Mookerjee, B., Zaver, M. B., Sutter, C. H., Artemov, D., Zeng, W., Dillehay, L. E., Madan, A., Semenza, G. L., and Bedi, A. (2000) Genes Dev. 14, 34-44
15. Blagosklonny, M. V., Won, G. A., Romanova, L. Y., Trepel, J., Fojo, T., and Neckers, L. (1998) J. Biol. Chem. 273, 11995-11998
16. Chen, D., Li, M., Luo, J., and Gu, W. (2003) J. Biol. Chem. 278, 13595-13598
17. Nieminen, A. L., Qanungo, S., Schneider, E. A., Jiang, B. H., and Agani, F. H. (2005) J. Cell. Physiol. 204, 364-369
18. Chen, Y., and Swanson, R. A. (2003) J. Cereb. Blood Flow Metab. 23, 137-149
19. Wick, A., Wick, W., Waltenberger, J., Weller, M., Dichgans, J., and Schulz, J. B. (2002) J. Neurosci. 22, 6401-6407
20. Ruscher, K., Freyer, D., Karsch, M., Isaev, N., Megow, D., Sawitzki, B., Priller, J., Dirnagl, U., and Meisel, A. (2002) J. Neurosci. 22, 10291-10301
21. Halterman, M. W., Miller, C. C., and Federoff, H. J. (1999) J. Neurosci. 19, 6818-6824
22. Calvert, J. W. C., Yamaguchi-Okada, M., and Zhang, J. H. (2006) J. Appl. Physiol. 101, 853-865
23. Chung, Y. H., Shin, C. M., Kim, M. J., Lee, E. Y., Kim, G., and Cha, C. I. (2002) Neurol. Res. 24, 324-328
24. Andrews, N. C., and Faller, D. V. (1991) Nucleic Acids Res. 19, 2499
25. Brunelle, J. K., Santore, M. T., Budinger, G. R. S., Tang, Y., Barrett, T. A., Zong, W.-X., Kandel, E., Keith, B., Simon, M. C., Thompson, C. B., Hay, N., and Chandel, N. S. (2004) J. Biol. Chem. 279, 4305-4312
26. Ryan, H. E., Poloni, M., McNulty, W., Elson, D., Gassmann, M., Arbeit, J. M., and Johnson, R. S. (2000) Cancer Res. 60, 4010-4015
27. Zhuo, L., Theis, M., Alvarez-Maya, I., Brenner, M., Willecke, K., and Messing, A. (2001) Genesis 31, 85-94
28. Meuwissen, R., Linn, S. C., Linnoila, R. I., Zevenhoven, J., Mooi, W. J., and Berns, A. (2003) Cancer Cell 4, 181-189
29. Montes de Oca Luna, R., Wagner, D. S., and Lozano, G. (1995) Nature 378, 203-206
30. Hayashi, S., and McMahon, A. P. (2002) Dev. Biol. 244, 305-318
31. Vengellur, A., Woods, B. G., Ryan, H. E., Johnson, R. S., and LaPres, J. J. (2003) Gene Expr. 11, 181-197
32. Huang, Y., Hickey, R. P., Yeh, J. L., Liu, D., Dadak, A., Young, L. H., Johnson, R. S., and Giordano, F. J. (2004) FASEB J. 18, 1138-1140
33. Helton, R., Cui, J., Scheel, J. R., Ellison, J. A., Ames, C., Gibson, C., Blouw, B., Ouyang, L., Dragatsis, I., Zeitlin, S., Johnson, R. S., Lipton, S. A., and Barlow, C. (2005) J. Neurosci. 25, 4099-4107
34. Chavez, J. C., Baranova, O., Lin, J., and Pichiule, P. (2006) J. Neurosci. 26, 9471-9481
35. Gruber, M., Hu, C.-J., Johnson, R. S., Brown, E. J., Keith, B., and Simon, M. C. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 2301-2306
36. Bonini, P., Cicconi, S., Cardinale, A., Vitale, C., Serafino, A. L., Ciotti, M. T., and Marlier, L. N. (2004) J. Neurosci. Res. 75, 83-95
37. Koumenis, C., Alarcon, R., Hammond, E., Sutphin, P., Hoffman, W., Murphy, M., Derr, J., Taya, Y., Lowe, S., Kastan, M., and Giaccia, A. (2001) Mol. Cell. Biol. 21, 1297-1310
38. Kim, J.-Y., Ahn, H.-J., Ryu, J.-H., Suk, K., and Park, J.-H. (2004) J. Exp. Med. 199, 113-124
39. Goda, N., Ryan, H. E., Khadivi, B., McNulty, W., Rickert, R. C., and Johnson, R. S. (2003) Mol. Cell. Biol. 23, 359-369
40. Mekhail, K., Gunaratnam, L., Bonicalzi, M. E., and Lee, S. (2004) Nat. Cell Biol. 6, 642-647
41. Paltoglou, S. M., and Roberts, B. J. (2005) Oncogene 24, 3830-3835
42. Morris, E. J., and Geller, H. M. (1996) J. Cell Biol. 134, 757-770
43. Bardos, J. I., Chau, N. M., and Ashcroft, M. (2004) Mol. Cell. Biol. 24, 2905-2914
44. Park, S. K., Dadak, A. M., Haase, V. H., Fontana, L., Giaccia, A. J., and Johnson, R. S. (2003) Mol. Cell. Biol. 23, 4959-4971
45. Hu, C. J., Wang, L.-Y., Chodosh, L. A., Keith, B., and Simon, M. C. (2003) Mol. Cell. Biol. 23, 9361-9374
46. Levy, N. S., Chung, S., Furneaux, H., and Levy, A. P. (1998) J. Biol. Chem. 273, 6417-6423
47. Wang, V., Davis, D. A., Haque, M., Huang, L. E., and Yarchoan, R. (2005) Cancer Res. 65, 3299-3306
48. Greijer, A. E., van der Groep, P., Kemming, D., Shvarts, A., and Semenza, G. L. (2005) J. Pathol. 206, 291-304
49. Schuler, M., and Green, D. R. (2001) Biochem. Soc. Trans. 29, 684-688
50. Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T., Taniguchi, T., and Tanaka, N. (2000) Science 288, 1053-1058
51. Wenger, R. H., Camenisch, G., Desbaillets, I., Chilov, D., and Gassmann, M. (1998) Cancer Res. 58, 5678-5680
52. Rapisarda, A., Uranchimeg, B., Sordet, O., Pommier, Y., Shoemaker, R. H., and Melillo, G. (2004) Cancer Res. 64, 1475-1482
53. Rapisarda, A., Uranchimeg, B., Scudiero, D. A., Selby, M., Sausville, E. A., Shoemaker, R. H., and Melillo, G. (2002) Cancer Res. 62, 4316-4324