Ligand, modulatory, and co-receptor functions of neural glycans

Frontiers in Bioscience

Volumn 12, Issue 10, 2007, Pages 3852-3879

  Matani, Parul ^a   Sharrow, Mary ^c   Tiemeyer, Michael ^b,c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Georgia ^*  (United States)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

Alpha Dystroglycan; Axon guidance; Cell adhesion; Fringe; Galectin; Glycosaminoglycan; Glycosylation; I type lectin; Lectican; NCAM; Neural glycan; Neural lectin; Notch; Review; Siglec; Sulfation

Indexed keywords

CELL SURFACE RECEPTOR; LIGAND; POLYSACCHARIDE;

METABOLISM; REVIEW;

LIGANDS; POLYSACCHARIDES; RECEPTORS, CELL SURFACE;

EID: 34347224363     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/2356     Document Type: Article

References (284)

1. Varki A.: Biological roles of oligosaccharides. Glycobiology 3, 97-130 (1993)
2. Gagneux P. & A. Varki: Evolutionary considerations in relating oligosaccharide diversity to biological function. Glycobiology 9, 747-55 (1999) (Pubitemid 29376001)
3. Feizi T.: Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens. Nature 314, 53-57 (1985) (Pubitemid 15142022)
4. Haltiwanger R. S. & J. B. Lowe: Role of glycosylation in development. Annu Rev Biochem 73, 491-537 (2004) (Pubitemid 39050378)
5. Lowe J. B.: Glycosylation, immunity and autoimmunity. Cell 104, 809-812 (2001)
6. Crocker P. R.: Siglecs: sialic-acid-binding immunoglobulin-like lectins in cell-cell interactions and signalling. Curr Opin Struct Biol 12, 609-15 (2002) (Pubitemid 35449068)
7. Kleene R. & M. Schachner: Glycans and neural cell interactions. Nat Rev Neurosci 5, 195-208 (2004) (Pubitemid 38252476)
8. Schnaar R. L.: Glycolipid-mediated cell-cell recognition in inflammation and nerve regeneration. Arch Biochem Biophys 426, 163-72 (2004) (Pubitemid 38680614)
9. Bruses J. L. & U. Rutishauser: Roles, regulation, and mechanism of polysialic acid function during neural development. Biochimie 83, 635-43 (2001) (Pubitemid 32821227)
10. Yamaguchi Y.: Glycobiology of the synapse: the role of glycans in the formation, maturation, and modulation of synapses. Biochim Biophys Acta 1573, 369-76 (2002) (Pubitemid 35335446)
11. Grimpe B., Y. Pressman, M. D. Lupa, K. P. Horn, M. B. Bunge & J. Silver: The role of proteoglycans in Schwann cell/astrocyte interactions and in regeneration failure at PNS/CNS interfaces. Mol Cell Neurosci 28, 18-29 (2005) (Pubitemid 39656008)
12. Steinmetz M. P., K. P. Horn, V. J. Tom, J. H. Miller, S. A. Busch, D. Nair, D. J. Silver & J. Silver: Chronic enhancement of the intrinsic growth capacity of sensory neurons combined with the degradation of inhibitory proteoglycans allows functional regeneration of sensory axons through the dorsal root entry zone in the mammalian spinal cord. J Neurosci 25, 8066-76 (2005) (Pubitemid 41254410)
13. Koprivica V., K. S. Cho, J. B. Park, G. Yiu, J. Atwal, B. Gore, J. A. Kim, E. Lin, M. Tessier-Lavigne, D. F. Chen & Z. He: EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans. Science 310, 106-10 (2005) (Pubitemid 41434546)
14. Oakley R. A., C. J. Lasky, C. A. Erickson & K. W. Tosney: Glycoconjugates mark a transient barrier to neural crest migration in the chicken embryo. Development 120, 103-14 (1994) (Pubitemid 24031192)
15. Wandall H. H., J. W. Pedersen, C. Park, S. B. Levery, S. Pizette, S. M. Cohen, T. Schwientek & H. Clausen: Drosophila egghead encodes a beta 1, 4-mannosyltransferase predicted to form the immediate precursor glycosphingolipid substrate for brainiac. J Biol Chem 278, 1411-4 (2003) (Pubitemid 36801365)
16. Katic I., L. G. Vallier & I. Greenwald: New positive regulators of lin-12 activity in Caenorhabditis elegans include the BRE-5/Brainiac glycosphingolipid biosynthesis enzyme. Genetics 171, 1605-15 (2005)
17. Allende M. L. & R. L. Proia: Lubricating cell signaling pathways with gangliosides. Curr Opin Struct Biol 12, 587-92 (2002) (Pubitemid 35449065)
18. Carulli D., T. Laabs, H. M. Geller & J. W. Fawcett: Chondroitin sulfate proteoglycans in neural development and regeneration. Curr Opin Neurobiol 15, 116-20 (2005) (Pubitemid 40249970)
19. Properzi F., R. A. Asher & J. W. Fawcett: Chondroitin sulphate proteoglycans in the central nervous system: changes and synthesis after injury. Biochem Soc Trans 31, 335-6 (2003) (Pubitemid 36520669)
20. Silver J.: Inhibitory molecules in development and regeneration. J Neurol 242, S22-4 (1994) (Pubitemid 24367036)
21. Faissner A. & D. Steindler: Boundaries and inhibitory molecules in developing neural tissues. Glia 13, 233-54 (1995)
22. Miljan E. A. & E. G. Bremer: Regulation of growth factor receptors by gangliosides. Sci STKE 2002, RE15 (2002)
23. Roseman S.: The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion. Chem Phys Lipids 5, 270-97 (1970)
24. Roth S., E. J. McGuire & S. Roseman: Evidence for cell-surface glycosyltransferases. Their potential role in cellular recognition. J Cell Biol 51, 536-47 (1971)
25. Chen Y. J., D. R. Wing, G. R. Guile, R. A. Dwek, D. J. Harvey & S. Zamze: Neutral N-glycans in adult rat brain tissue-complete characterization reveals fucosylated hybrid and complex structures. Eur J Biochem 251, 691-703 (1998) (Pubitemid 28108963)
26. Chou D. K. H., N. Prasadarao, O. Koul & F. B. Jungalwala: Developmental expression of HNK-1 reactive antigens in rat cerebral cortex and molecular heterogeneity of sulfoglucuronylneolactotetraosylceramide in CNS versus PNS. J Neurochem 57, 852-859 (1991)
27. Dodd J., D. Solter & T. M. Jessell: Monoclonal antibodies against carbohydrate differentiation antigens identify subsets of primary sensory neurones. Nature 311, 469-72 (1984) (Pubitemid 14035454)
28. Finne J.: Occurence of unique polysialosyl carbohydrate units in glycoproteins of developing brain. J Biol Chem 257, 11966-11970 (1982) (Pubitemid 13168885)
29. Seki T. & Y. Arai: The persistent expression of a highly polysialylated NCAM in the dentate gyrus of the adult rat. Neurosci Res 12, 503-13 (1991)
30. Zamze S., D. J. Harvey, P. Pesheva, T. S. Mattu, M. Schachner, R. A. Dwek & D. R. Wing: Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "braintype" neutral N-glycans. Glycobiology 9, 823-831 (1999) (Pubitemid 29376009)
31. Fishman P. H. & R. O. Brady: Biosynthesis and function of gangliosides. Science 194, 906-15 (1976)
32. Kruse J., R. Mailhammer, H. Wernecke, A. Faissner, I. Sommer, C. Goridis & M. Schachner: Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1. Nature 311, 153-5 (1984) (Pubitemid 14072204)
33. Ilyas A. A., R. H. Quarles & R. O. Brady: The monoclonal antibody HNK-1 reacts with a human peripheral nerve ganglioside. Biochem Biophys Res Commun 122, 1206-11 (1984) (Pubitemid 14073556)
34. Tole S., Z. Kaprielian, S. K. Ou & P. H. Patterson: FORSE-1: a positionally regulated epitope in the developing rat central nervous system. J Neurosci 15, 957-69 (1995)
35. Constantine-Paton M., A. S. Blum, R. Mendez-Otero & C. J. Barnstable: A cell surface molecule distributed in a dorsoventral gradient in the perinatal rat retina. Nature 324, 459-62 (1986) (Pubitemid 17184161)
36. Schwarting G. A. & J. E. Crandall: Subsets of olfactory and vomeronasal sensory epithelial cells and axons revealed by monoclonal antibodies to carbohydrate antigens. Brain Res 547, 239-48 (1991)
37. Allen W. K. & R. Akeson: Identification of a cell surface glycoprotein family of olfactory receptor neurons with a monoclonal antibody. J Neurosci 5, 284-96 (1985) (Pubitemid 15133146)
38. Dodd J. & T. W. Jessell: Lactoseries carbohydrates specify subsets of dorsal root ganglion neurons projecting to the superficial dorsal horn of rat spinal cord. J Neurosci 5, 3278-3294 (1985) (Pubitemid 16182608)
39. Regan L. J., J. Dodd, S. H. Barondes & T. M. Jessell: Selective expression of endogenous lactose-binding lectins and lactoseries glycoconjugates in subsets of rat sensory neurons. Proc Natl Acad Sci U S A 83, 2248-52 (1986) (Pubitemid 16020872)
40. Allendoerfer K. L., J. L. Magnani & P. H. Patterson: FORSE-1, an antibody that labels regionally restricted subpopulations of progenitor cells in the embryonic central nervous system, recognizes the Le (x) carbohydrate on a proteoglycan and two glycolipid antigens. Mol Cell Neurosci 6, 381-95 (1995)
41. Rollenhagen A., R. Czaniera, M. Albert, E. S. Wintergerst & M. Schachner: Immunocytological localization of the HNK-1 carbohydrate in murine cerebellum, hippocampus and spinal cord using monoclonal antibodies with different epitope specificities. J Neurocytol 30, 337-51 (2001)
42. Hockfield S. & R. D. McKay: A surface antigen expressed by a subset of neurons in the vertebrate central nervous system. Proc Natl Acad Sci U S A 80, 5758-61 (1983) (Pubitemid 14249907)
43. Lander C., P. Kind, M. Maleski & S. Hockfield: A family of activity-dependent neuronal cell-surface chondroitin sulfate proteoglycans in cat visual cortex. J Neurosci 17, 1928-39 (1997) (Pubitemid 27106752)
44. Zhao Z., D. K. Chou, S. M. Nair, S. Tobet & F. B. Jungalwala: Expression of sulfoglucuronyl (HNK-1) carbohydrate and its binding protein (SBP-1) in developing rat cerebellum. Brain Res Dev Brain Res 120, 165-80 (2000) (Pubitemid 30209909)
45. Zhao Z., S. M. Nair, D. K. Chou, S. A. Tobet & F. B. Jungalwala: Expression and role of sulfoglucuronyl (HNK-1) carbohydrate and its binding protein SBP-1 in developing rat cerebral cortex. J Neurosci Res 62, 186-205 (2000)
46. Seppo A., M. Moreland, H. Schweingruber & M. Tiemeyer: Zwitterionic and acidic glycosphingolipids of the Drosophila melanogaster embryo. Eur J Biochem 267, 3549-58 (2000) (Pubitemid 30423015)
47. Seppo A. & M. Tiemeyer: Function and structure of Drosophila glycans. Glycobiology 10, 751-760 (2000) (Pubitemid 30642692)
48. Zipser B. & R. N. Cole: A mannose-specific recognition mediates the defasciculation of axons in the leech CNS. J Neurosci 11, 3471-3480 (1991)
49. Zipser B., J. J. Bradford & R. I. Hollingsworth: Structural analysis of leech galactocerebrosides using 1D and 2D NMR spectroscopy, gas chromatography-mass spectrometry, and FAB mass spectrometry. Carbohydr Res 308, 47-55 (1998) (Pubitemid 28295039)
50. Katz F., W. Moats & Y. N. Jan: A carbohydrate epitope expressed uniquely on the cell surface of Drosophila neurons is altered in the mutant nac (neurally altered carbohydrate). EMBO J 7, 3471-3477 (1988)
51. Snow P. M., N. H. Patel, A. L. Harrelson & C. S. Goodman: Neural-specific carbohydrate moiety shared by many surface glycoproteins in Drosophila and grasshopper embryos. J Neurosci 7, 4137-4144 (1987) (Pubitemid 18012424)
52. Fan X., Y. M. She, R. D. Bagshaw, J. W. Callahan, H. Schachter & D. J. Mahuran: Identification of the hydrophobic glycoproteins of Caenorhabditis elegans. Glycobiology 15, 952-64 (2005) (Pubitemid 41518746)
53. Leonard R., D. Rendic, C. Rabouille, I. B. Wilson, T. Preat & F. Altmann: The Drosophila fused lobes gene encodes an N-acetylglucosaminidase involved in N-glycan processing. J Biol Chem 281, 4867-75 (2006) (Pubitemid 43847748)
54. Dityatev A., G. Dityateva, V. Sytnyk, M. Delling, N. Toni, I. Nikonenko, D. Muller & M. Schachner: Polysialylated neural cell adhesion molecule promotes remodeling and formation of hippocampal synapses. J Neurosci 24, 9372-82 (2004) (Pubitemid 39426174)
55. Pan B., S. E. Fromholt, E. J. Hess, T. O. Crawford, J. W. Griffin, K. A. Sheikh & R. L. Schnaar: Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: neuropathology and behavioral deficits in single-and double-null mice. Exp Neurol 195, 208-17 (2005) (Pubitemid 41116825)
56. Song J. & B. Zipser: Targeting of neuronal subsets mediated by their sequentially expressed carbohydrate markers. Neuron 14, 537-547 (1995)
57. Storan M. J., T. Magnaldo, M. C. Biol-N'Garagba, Y. Zick & B. Key: Expression and putative role of lactoseries carbohydrates present on NCAM in the rat primary olfactory pathway. J Comp Neurol 475, 289-302 (2004) (Pubitemid 38850003)
58. Whitlock K. E.: Development of Drosophila wing sensory neurons in mutants with missing or modified cell surface molecules. Development 117, 1251-1260 (1993) (Pubitemid 23154491)
59. Misevic G. N., J. Finne & M. M. Burger: Involvement of carbohydrates as multiple low affinity interaction sites in the self-association of the aggregation factor from the marine sponge Microciona prolifera. J Biol Chem 262, 5870-7 (1987)
60. Fenderson B. A., E. M. Eddy & S. Hakomori: Glycoconjugate expression during embryogenesis and its biological significance. Bioessays 12, 173-9 (1990) (Pubitemid 120034352)
61. Eggens I., B. A. Fenderson, T. Toyokuni & S. Hakomori: A role of carbohydrate-carbohydrate interaction in the process of specific cell recognition during embryogenesis and organogenesis: a preliminary note. Biochem Biophys Res Commun 158, 913-20 (1989) (Pubitemid 19076011)
62. Marchase R. B.: Biochemical investigations of retinotectal adhesive specificity. J Cell Biol 75, 237-57 (1977) (Pubitemid 8190670)
63. Shur B. D.: Glycosyltransferases as cell adhesion molecules. Curr Opin Cell Biol 5, 854-63 (1993)
64. Fenteany F. H. & K. J. Colley: Multiple signals are required for alpha2, 6-sialyltransferase (ST6Gal1) oligomerization and Golgi localization. J Biol Chem 280, 5423-5429 (2005) (Pubitemid 40280017)
65. Jaskiewicz E., G. Zhu, R. Bassi, D. S. Darling & W. W. J. Young: Beta1, 4-N-acetylgalactosaminyltransferase (GM2 synthase) is released from Golgi membranes as a neuraminidase-sensitive, disulfide-bonded dimer by a cathepsin D-like protease. J Biol Chem 271, 26395-26403 (1996) (Pubitemid 26347495)
66. Rodeheffer C. & B. D. Shur: Targeted mutations in beta1, 4-galactosyltransferase I reveal its multiple cellular functions. Biochim Biophys Acta 1573, 258-270 (2002) (Pubitemid 35335436)
67. Stern C. A. & M. Tiemeyer: A ganglioside-specific sialyltransferase localizes to axons and non-Golgi structures in neurons. J Neurosci 21, 1434-43 (2001) (Pubitemid 32182185)
68. Jessell T. M., M. A. Hynes & J. Dodd: Carbohydrates and carbohydrate-binding proteins in the nervous system. Annu Rev Neurosci 13, 227-255 (1990) (Pubitemid 20100650)
69. Zanetta J. P.: Structure and functions of lectins in the central and peripheral nervous system. Acta Anat (Basel) 161, 180-95 (1998)
70. Thomas W. A., J. Thomson, J. L. Magnani & M. S. Steinberg: Two distinct adhesion mechanisms in embryonic neural retina cells. III. Functional specificity. Dev Biol 81, 379-85 (1981) (Pubitemid 11186338)
71. Thomas W. A. & M. S. Steinberg: Two distinct adhesion mechanisms in embryonic neural retina cells. II. An immunological analysis. Dev Biol 81, 106-14 (1981) (Pubitemid 11182729)
72. Steinberg M. S.: Adhesion in development: an historical overview. Dev Biol 180, 377-88 (1996) (Pubitemid 27037347)
73. Blackburn C. C., P. Swank-Hill & R. L. Schnaar: Gangliosides support neural retina cell adhesion. J Biol Chem 261, 2873-81 (1986) (Pubitemid 17218305)
74. Tiemeyer M., P. Swank-Hill & R. L. Schnaar: A membrane receptor for gangliosides is associated with central nervous system myelin. J Biol Chem 265, 11990-9 (1990)
75. Lehmann S., S. Kuchler, M. Theveniau, G. Vincendon & J. P. Zanetta: An endogenous lectin and one of its neuronal glycoprotein ligands are involved in contact guidance of neuron migration. Proc Natl Acad Sci U S A 87, 6455-9 (1990)
76. Kuchler S., J. P. Zanetta, M. Zaepfel, A. Badache, L. L. Sarlieve, G. Vincendon & J. M. Matthieu: The endogenous lectin cerebellar soluble lectin and its ligands in central nervous system myelin of myelin-deficient (mld) mutant mice. J Neurochem 56, 436-45 (1991) (Pubitemid 21901981)
77. Badache A., D. Burger, H. Villarroya, Y. Robert, S. Kuchler, A. J. Steck & J. P. Zanetta: Carbohydrate moieties of myelin-associated glycoprotein, major glycoprotein of the peripheral nervous system myelin and other myelin glycoproteins potentially involved in cell adhesion. Dev Neurosci 14, 342-50 (1992) (Pubitemid 23124843)
78. Danguy A., I. Camby & R. Kiss: Galectins and cancer. Biochim Biophys Acta 1572, 285-93 (2002) (Pubitemid 35246351)
79. Liu F. T., R. J. Patterson & J. L. Wang: Intracellular functions of galectins. Biochim Biophys Acta 1572, 263-73 (2002) (Pubitemid 35246349)
80. Hirabayashi J., T. Hashidate, Y. Arata, N. Nishi, T. Nakamura, M. Hirashima, T. Urashima, T. Oka, M. Futai, W. E. Muller, F. Yagi & K. Kasai: Oligosaccharide specificity of galectins: a search by frontal affinity chromatography. Biochim Biophys Acta 1572, 232-54 (2002) (Pubitemid 35246347)
81. Brewer C. F.: Binding and cross-linking properties of galectins. Biochim Biophys Acta 1572, 255-62 (2002)
82. Ahmad N., H. J. Gabius, S. Andre, H. Kaltner, S. Sabesan, R. Roy, B. Liu, F. Macaluso & C. F. Brewer: Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous crosslinked complexes. J Biol Chem 279, 10841-7 (2004) (Pubitemid 38401573)
83. Brewer C. F., M. C. Miceli & L. G. Baum: Clusters, bundles, arrays and lattices: novel mechanisms for lectinsaccharide-mediated cellular interactions. Curr Opin Struct Biol 12, 616-23 (2002) (Pubitemid 35449069)
84. He J. & L. G. Baum: Presentation of galectin-1 by extracellular matrix triggers T cell death. J Biol Chem 279, 4705-12 (2004) (Pubitemid 38199064)
85. Nguyen J. T., D. P. Evans, M. Galvan, K. E. Pace, D. Leitenberg, T. N. Bui & L. G. Baum: CD45 modulates galectin-1-induced T cell death: regulation by expression of core 2 O-glycans. J Immunol 167, 5697-707 (2001) (Pubitemid 33062760)
86. Perillo N. L., C. H. Uittenbogaart, J. T. Nguyen & L. G. Baum: Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes. J Exp Med 185, 1851-8 (1997) (Pubitemid 27242206)
87. Henion T. R., D. Raitcheva, R. Grosholz, F. Biellmann, W. C. Skarnes, T. Hennet & G. A. Schwarting: Beta1, 3-N-acetylglucosaminyltransferase 1 glycosylation is required for axon pathfinding by olfactory sensory neurons. J Neurosci 25, 1894-903 (2005) (Pubitemid 40289394)
88. Crandall J. E., C. Dibble, D. Butler, L. Pays, N. Ahmad, C. Kostek, A. W. Puschel & G. A. Schwarting: Patterning of olfactory sensory connections is mediated by extracellular matrix proteins in the nerve layer of the olfactory bulb. J Neurobiol 45, 195-206 (2000)
89. Horie H., Y. Inagaki, Y. Sohma, R. Nozawa, K. Okawa, M. Hasegawa, N. Muramatsu, H. Kawano, M. Horie, H. Koyama, I. Sakai, K. Takeshita, Y. Kowada, M. Takano & T. Kadoya: Galectin-1 regulates initial axonal growth in peripheral nerves after axotomy. J Neurosci 19, 9964-74 (1999) (Pubitemid 30226668)
90. Fukaya K., M. Hasegawa, T. Mashitani, T. Kadoya, H. Horie, Y. Hayashi, H. Fujisawa, O. Tachibana, S. Kida & J. Yamashita: Oxidized galectin-1 stimulates the migration of Schwann cells from both proximal and distal stumps of transected nerves and promotes axonal regeneration after peripheral nerve injury. J Neuropathol Exp Neurol 62, 162-72 (2003) (Pubitemid 36176951)
91. Horie H., T. Kadoya, N. Hikawa, K. Sango, H. Inoue, K. Takeshita, R. Asawa, T. Hiroi, M. Sato, T. Yoshioka & Y. Ishikawa: Oxidized galectin-1 stimulates macrophages to promote axonal regeneration in peripheral nerves after axotomy. J Neurosci 24, 1873-80 (2004) (Pubitemid 38292798)
92. McGraw J., L. T. McPhail, L. W. Oschipok, H. Horie, F. Poirier, J. D. Steeves, M. S. Ramer & W. Tetzlaff: Galectin-1 in regenerating motoneurons. Eur J Neurosci 20, 2872-80 (2004) (Pubitemid 40007281)
93. Oetke C., M. C. Vinson, C. Jones & P. R. Crocker: Sialoadhesin-deficient mice exhibit subtle changes in B-and T-cell populations and reduced immunoglobulin M levels. Mol Cell Biol 26, 1549-57 (2006) (Pubitemid 43202578)
94. Munday J., H. Floyd & P. R. Crocker: Sialic acid binding receptors (siglecs) expressed by macrophages. J Leuk Biol 66, 705-11 (1999) (Pubitemid 29532027)
95. Crocker P. R., E. A. Clark, M. Filbin, S. Gordon, Y. Jones, J. H. Kehrl, S. Kelm, N. Le Douarin, L. Powell, J. Roder, R. L. Schnaar, D. C. Sgroi, K. Stamenkovic, R. Schauer, M. Schachner, T. K. van den Berg, P. A. van der Merwe, S. M. Watt & A. Varki: Siglecs: a family of sialicacid binding lectins. Glycobiology 8, v (1998)
96. Powell L. D. & A. Varki: The oligosaccharide binding specificities of CD22 beta, a sialic acid-specific lectin of B cells. J Biol Chem 269, 10628-36 (1994)
97. Varki A. & T. Angata: Siglecs-the major subfamily of I-type lectins. Glycobiology 16, 1R-27R (2006) (Pubitemid 43009801)
98. Collins B. E., H. Ito, N. Sawada, H. Ishida, M. Kiso & R. L. Schnaar: Enhanced binding of the neural siglecs, myelin-associated glycoprotein and Schwann cell myelin protein, to Chol-1 (alpha-series) gangliosides and novel sulfated Chol-1 analogs. J Biol Chem 274, 37637-43 (1999) (Pubitemid 30026820)
99. Probstmeier R. & P. Pesheva: I-type lectins in the nervous system. Prog Neurobiol 58, 163-84 (1999) (Pubitemid 29183040)
100. Horstkorte R., M. Schachner, J. P. Magyar, T. Vorherr & B. Schmitz: The fourth immunoglobulin-like domain of NCAM contains a carbohydrate recognition domain for oligomannosidic glycans implicated in association with L1 and neurite outgrowth. J Cell Biol 121, 1409-21 (1993)
101. Filbin M. T., F. S. Walsh, B. D. Trapp, J. A. Pizzey & G. I. Tennekoon: Role of myelin P0 protein as a homophilic adhesion molecule. Nature 344, 871-2 (1990)
102. Filbin M. T. & G. I. Tennekoon: Homophilic adhesion of the myelin P0 protein requires glycosylation of both molecules in the homophilic pair. J Cell Biol 122, 451-9 (1993) (Pubitemid 23210471)
103. Voshol H., C. W. van Zuylen, G. Orberger, J. F. Vliegenthart & M. Schachner: Structure of the HNK-1 carbohydrate epitope on bovine peripheral myelin glycoprotein P0. J Biol Chem 271, 22957-60 (1996) (Pubitemid 26314723)
104. Shapiro L., J. P. Doyle, P. Hensley, D. R. Colman & W. A. Hendrickson: Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin. Neuron 17, 435-49 (1996) (Pubitemid 26322215)
105. Dietrich J. B.: The adhesion molecule ICAM-1 and its regulation in relation with the blood-brain barrier. J Neuroimmunol 128, 58-68 (2002)
106. Bella J., P. R. Kolatkar, C. W. Marlor, J. M. Greve & M. G. Rossmann: The structure of the two amino-terminal domains of human ICAM-1 suggests how it functions as a rhinovirus receptor and as an LFA-1 integrin ligand. Proc Natl Acad Sci USA 95, 4140-4145 (1998) (Pubitemid 28207878)
107. Entwistle J., C. L. Hall & E. A. Turley: HA receptors: regulators of signalling to the cytoskeleton. J Cell Biochem 61, 569-577 (1996) (Pubitemid 26240134)
108. Gustafson S., T. Bjorkman, N. Forsberg, T. Lind, T. Wikstrom & K. Lidholt: Accessible hyaluronan receptors identical to ICAM-1 in mouse mast-cell tumours. Glycoconj J 12, 350-355 (1995)
109. McCourt P. A., B. Ek, N. Forsberg & S. Gustafson: Intercellular adhesion molecule-1 is a cell surface receptor for hyaluronan. J Biol Chem 269, 30081-30084 (1994) (Pubitemid 24376465)
110. Colonna M., H. Makajima, F. Navarro & M. Lopez-Botet: A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells. J Leuk Biol 66, 375-381 (1999) (Pubitemid 29439243)
111. Haspel J. & M. Grumet: The L1CAM extracellular region: a multi-domain protein with modular and cooperative binding modes. Front Biosci 8, s1210-s1225 (2003) (Pubitemid 38925382)
112. Srinivasan M. & R. W. Roeske: Immunomodulatory peptides from IgSF proteins: a review. Curr Protein Pept Sci 6, 185-196 (2005) (Pubitemid 40614141)
113. Schnaar R. L., B. E. Collins, L. P. Wright, M. Kiso, M. B. Tropak, J. C. Roder & P. R. Crocker: Myelin-associated glycoprotein binding to gangliosides. Structural specificity and functional implications. Ann N Y Acad Sci 845, 92-105 (1998)
114. Wu A. M. & S. J. Sugii: Differential binding properties of GalNAc and/or Gal specific lectins. Adv Exp Med Biol 228, 205-63 (1988)
115. Yang L. J., C. B. Zeller, N. L. Shaper, M. Kiso, A. Hasegawa, R. E. Shapiro & R. L. Schnaar: Gangliosides are neuronal ligands for myelin-associated glycoprotein. Proc Natl Acad Sci U S A 93, 814-8 (1996) (Pubitemid 26041175)
116. Trapp B. D., S. B. Andrews, C. Cootauco & R. Quarles: The myelin-associated glycoprotein is enriched in multivesicular bodies and periaxonal membranes of actively myelinating oligodendrocytes. J Cell Biol 109, 2417-26 (1989) (Pubitemid 19282626)
117. Quarles R. H. & B. D. Trapp: Localization of myelin-associated glycoprotein. J Neurochem 43, 1773-7 (1984)
118. Ito H., H. Ishida, H. Waki, S. Ando & M. Kiso: Total synthesis of a cholinergic neuron-specific ganglioside GT1a alpha: a high affinity ligand for myelin-associated glycoprotein (MAG). Glycoconj J 16, 585-98 (1999) (Pubitemid 30453736)
119. Yamashita T., Y.-P. Wu, R. Sandhoff, N. Werth, H. Mizukami, J. M. Ellis, J. L. Dupree, R. Geyer, K. Sandhoff & R. L. Proia: Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions. Proc Natl Acad Sci USA 102, 2725-2730 (2005) (Pubitemid 40299860)
120. Chiavegatto S., J. Sun, R. J. Nelson & R. L. Schnaar: A functional role for complex gangliosides: motor deficits in GM2/GD2 synthase knockout mice. Exp Neurol 166, 227-34 (2000)
121. Proia R. L.: Glycosphingolipid functions: insights from engineered mouse models. Philos Trans R Soc Lond B Biol Sci 358, 879-83 (2003) (Pubitemid 36639712)
122. GrandPre T., F. Nakamura, T. Vartanian & S. M. Strittmatter: Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein. Nature 403, 439-444 (2000) (Pubitemid 30073094)
123. Hu F. & S. M. Strittmatter: Regulating axon growth within the postnatal central nervous system. Semin Perinatol 28, 371-378 (2004) (Pubitemid 40037563)
124. Liu B. P., A. E. Fournier, T. GrandPre & S. M. Strittmatter: Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor. Science 297, 1190-1193 (2002) (Pubitemid 36193355)
125. Vourc'h P. & C. Andres: Oligodendrocyte myelin glycoprotein (OMgpP): evolution, structure and function. Brain Res Rev 45, 115-124 (2004) (Pubitemid 38656110)
126. Fournier A. E., T. GrandPre & S. M. Strittmatter: Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature 409, 341-346 (2001) (Pubitemid 32151238)
127. Woolf C. J. & S. Bloechlinger: It takes more than two to Nogo. Science 297, 1132-1134 (2002) (Pubitemid 36193336)
128. Barton W. A., B. P. Liu, D. Tzvetkova, P. D. Jeffrey, A. E. Fournier, D. Sah, R. Cate, S. M. Strittmatter & D. B. Nikolov: Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. EMBO J 22, 3291-3302 (2003) (Pubitemid 36834859)
129. Vourc'h P., T. Moreau, F. Arbion, S. Marouillat-Vedrine, J. P. Muh & C. Andres: Oligodendrocyte myelin glycoprotein growth inhibition function requires its conserved leucine-rich repeat domain, not its glycosylphosphatidyl- inositol anchor. J Neurochem 85, 889-897 (2003) (Pubitemid 36578621)
130. Venkatesh K., O. Chivatakarn, H. Le, P. S. Joshi, D. B. Kantor, B. A. Newman, R. Mage, C. Rader & R. J. Giger: The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent receptor selective for myelin-associated glycoprotein. J Neurosci 25, 808-822 (2005) (Pubitemid 40170995)
131. Vyas A. A., O. Blixt, J. C. Paulson & R. L. Schnaar: Potent glycan inhibitors of myelin-associated glycoprotein enhance axon outgrowth in vitro. J Biol Chem 280, 16305-10 (2005) (Pubitemid 40616758)
132. Vyas A. A., H. V. Patel, S. E. Fromholt, S. E. Heffer-Lauc, K. A. Vyas, J. Dang, M. Schachner & R. L. Schnaar: Gangliosides are functional nerve cell ligands for myelin-associated glycoprotein (MAG). Proc Natl Acad Sci USA 99, 8412-8417 (2002) (Pubitemid 34651066)
133. Dimou L., L. Schnell, L. Montani, C. Duncan, M. Simonen, R. Schneider, T. Liebscher, M. Gullo & M. E. Schwab: Nogo-A-deficient mice reveal strain-dependent differences in axonal regeneration. Journal of Neuroscience 26, 5591-5603 (2006) (Pubitemid 44315252)
134. Li S., J. E. Kim, S. Budel, T. G. Hampton & S. M. Strittmatter: Transgenic inhibition of Nogo-66 receptor function allows axonal sprouting and improved locomotion after spinal injury. Mol Cell Neurosci 29, 26-39 (2005) (Pubitemid 40613057)
135. Sun J., N. L. Shaper, S. Itonori, M. Heffer-Lauc, K. A. Sheikh & R. L. Schnaar: Myelin-associated glycoprotein (Siglec-4) expression is progressively and selectively decreased in the brains of mice lacking complex gangliosides. Glycobiology 14, 851-857 (2004) (Pubitemid 39206887)
136. Zheng B., J. Atwal, C. Ho, L. Case, X. L. He, K. C. Garcia, O. Steward & M. Tessier-Lavigne: Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo. Proc Natl Acad Sci USA 102, 1205-1210 (2005) (Pubitemid 40170750)
137. Park J. B., G. Yiu, S. Kaneko, J. L. Wang, J. Chang, X. L. He, K. C. Garcia & Z. He: A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors. Neuron 45, 345-351 (2005) (Pubitemid 40188202)
138. Schwab J. M., S. K. Tuli & V. Failli: The Nogo receptor complex: confining molecules to molecular mechanisms. Trends in Molecular Medicine 12, 293-297 (2006) (Pubitemid 44094289)
139. Shao Z., J. L. Browning, S. J. Lee, M. L. Scott, S. Shulga-Morskaya, N. Allaire, G. Thill, M. Levesque, D. Sah, J. M. McCoy, B. Murray, V. Jung, R. B. Pepinsky & S. Mi: TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration. Neuron 45, 353-359 (2005) (Pubitemid 40188203)
140. Yamashita T., H. Higuchi & M. Tohyama: The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho. J Cell Biol 157, 565-570 (2002) (Pubitemid 34839785)
141. Yang P., D. Major & U. Rutishauser: Role of charge and hydration in effects of polysialic acid on molecular interactions on and between cell membranes. J Biol Chem 269, 23039-23044 (1994) (Pubitemid 24283284)
142. Kiselyov V. V., V. Berezin, T. E. Maar, V. Soroka, K. Edvardsen, A. Schousboe & E. Bock: The first immunoglobulin-like neural cell adhesion molecule (NCAM) domain is involved in double-reciprocal interaction with the second immunoglobulin-like NCAM domain and in heparin binding. J Biol Chem 272, 10125-10134 (1997) (Pubitemid 27171689)
143. Gary S. C., G. M. Kelly & S. Hockfield: BEHAB/brevican: a brain-specific lectican implicated in gliomas and glial cell motility. Curr Opin Neurobiol 8, 576-581 (1998) (Pubitemid 28488417)
144. Rauch U., K. Feng & X. H. Zhou: Neurocan: a brain chondroitin sulfate proteoglycan. Cell Mol Life Sci 58, 1842-1856 (2001) (Pubitemid 33108773)
145. Yamaguchi Y.: Lecticans: organizers of the brain extracellular matrix. Cell Mol Life Sci 57, 276-289 (2000) (Pubitemid 30311415)
146. Aspberg A., C. Binkert & E. Roushalati: The versican C-type lectin domain recognizes the adhesion protein tenascin-R. Proc Natl Acad Sci USA 92, 10590-10594 (1995)
147. Aspberg A., R. Miura, S. Bourdoulous, M. Shimonaka, D. Heingard, M. Schachner, E. Roushalati & Y. Yamaguchi: The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety. Proc Natl Acad Sci USA 94, 10116-10121 (1997) (Pubitemid 27407003)
148. Aspberg A., S. Adam, G. Kostka, R. Timpl & D. Heingard: Fibulin-1 is a ligand for the C-type lectin domains of aggrecan and versican. J Biol Chem 274, 20444-20449 (1999)
149. Milev P., A. Chiba, M. Haring, H. Rauvala, M. Schachner, B. Ranscht, R. K. Margolis & R. U. Margolis: High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatasezeta/beta with tenascin-R, amphoterin, and the heparinbinding growth-associated molecule.
150. Miura R., A. Aspberg, I. M. Ethell, K. Hagihara, R. L. Schnaar, E. Ruoslahti & Y. Yamaguchi: The proteoglycan lectin domain binds sulfated cell surface glycolipids and promotes cell adhesion. J Biol Chem 274, 11431-11438 (1999)
151. Preobrazhensky A. A., A. Oohira, G. Maier, A. S. Voronina, T. S. Vovk & V. M. Barabanov: Identification of monoclonal antibody At5 as a new member of HNK-1 antibody family: the reactivity with myelin-associated glycoproteins and with two brain-specific proteoglycans, phosphacan and neurocan. Neurochem Res 22, 133-140 (1997)
152. Viapiano M. S., R. T. Matthews & S. Hockfield: A novel membrane-associated glycovariant of BEHAB/Brevican is up-regulated during rat brain development and in a rat model of invasive glioma. J Biol Chem 278, 33239-33247 (2003) (Pubitemid 37055773)
153. Matthews R. T., G. M. Kelly, C. A. Zerillo, M. Tiemeyer & S. Hockfield: Aggrecan glycoforms contribute to the molecular heterogeneity of perineuronal nets. J Neurosci 22, 7536-7547 (2002) (Pubitemid 35386355)
154. Nair S. M. & F. B. Jungalwala: Characterization of a sulfoglucuronyl carbohydrate binding protein in the developing nervous system. J Neurochem 68, 1286-1297 (1997) (Pubitemid 27086235)
155. Rauvala H., H. J. Huttunen, C. Fages, M. Kaksonen, T. Kinnunen, S. Imai, E. Raulo & I. Kilpelainen: Heparinbinding proteins HB-GAM (pleiotrophin) and amphoterin in the regulation of cell motility. Matrix Biol 19, 377-87 (2000)
156. Celio M. R. & I. Blumcke: Perineuronal nets-a specialized form of extracellular matrix in the adult nervous system. Brain Res Brain Res Rev 19, 128-145 (1994) (Pubitemid 24024086)
157. Carulli D., K. E. Rhodes, D. J. Brown, T. P. Bonnert, S. J. Pollack, K. Oliver, P. Strata & J. W. Fawcett: Composition of perineuronal nets in the adult rat cerebellum and the cellular origin of their components. J Comp Neurol 494, 559-577 (2006) (Pubitemid 43054232)
158. Deepa S. S., D. Carulli, C. Galtrey, K. Rhodes, J. Fukuda, T. Mikami, K. Sugahara & J. W. Fawcett: Composition of perineuronal net extracellular matrix in rat brain. J Biol Chem 281, 17789-17800 (2006)
159. Zaremba S., A. Guimaraes, R. G. Kalb & S. Hockfield: Characterization of an activity-dependent, neuronal surface proteoglycan identified with monoclonal antibody Cat-301. Neuron 2, 1207-1219 (1989)
160. Apostolova I., A. Irinitchev & M. Schachner: Tenascin-R restricts posttraumatic remodeling of motoneuron innervation and functional recovery after spinal cord injury in adult mice. J Neurosci 26, 7849-7859 (2006) (Pubitemid 44315154)
161. Bruckner G., J. Grosche, S. Schmidt, W. Hartig, R. U. Margolis, B. Delpech, C. I. Seidenbecher, R. Czaniera & M. Schachner: Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R. J Comp Neurol 428, 616-629 (2000)
162. Hagihara K., R. Miura, R. Kosaki, R. Berglund, B. Ranscht & Y. Yamaguchi: Immunohistochemical evidence for the Brevican-Tenascin-R interaction: Colocalization in perineuronal nets suggests a physiological role for the interaction in adult rat brain. J Comp Neurol 410, 256-264 (1999) (Pubitemid 29323076)
163. Pizzorusso T., P. Medini, N. Berardi, S. Chierzi, J. W. Fawcett & L. Maffei: Reactivation of ocular dominance plasticity in the adult visual cortex. Science 298, 1248-1251 (2002) (Pubitemid 35285495)
164. Helenius A. & M. Aebi: Roles of N-linked glycans in the endoplasmic reticulum. Annu Rev Biochem 73, 1019-1049 (2004) (Pubitemid 39050393)
165. Baenziger J. U. & E. D. Green: Pituitary glycoprotein hormone oligosaccharides: structure, synthesis and function of the asparagine-linked oligosaccharides on lutropin, follitropin and thyrotropin. Biochim Biophys Acta 947, 287-306 (1988)
166. Baenziger J. U.: Glycoprotein hormone GalNAc-4-sulphotransferase. Biochem Soc Trans 31, 326-30 (2003) (Pubitemid 36520667)
167. Fiete D. & J. U. Baenziger: Isolation of the SO4-4-GalNAcbeta1, 4GlcNAcbeta1, 2Manalpha-specific receptor from rat liver. J Biol Chem 272, 14629-37 (1997) (Pubitemid 27251725)
168. Fiete D., M. C. Beranek & J. U. Baenziger: The macrophage/endothelial cell mannose receptor cDNA encodes a protein that binds oligosaccharides terminating with SO4-4-GalNAcbeta1, 4GlcNAcbeta or Man at independent sites. Proc Natl Acad Sci U S A 94, 11256-61 (1997)
169. Baenziger J. U., S. Kumar, R. M. Brodbeck, P. L. Smith & M. C. Beranek: Circulatory half-life but not interaction with the lutropin/chorionic gonadotropin receptor is modulated by sulfation of bovine lutropin oligosaccharides. Proc Natl Acad Sci U S A 89, 334-8 (1992)
170. Mengeling B. J., S. M. Manzella & J. U. Baenziger: A cluster of basic amino acids within an alpha-helix is essential for alpha-subunit recognition by the glycoprotein hormone N-acetylgalactosaminyltransferase. Proc Natl Acad Sci USA 92, 502-506 (1995)
171. Kang H. G., M. R. Evers, G. Xia, J. U. Baenziger & M. Schachner: Molecular cloning and expression of an N-acetylgalactosamine-4-O- sulfotransferase that transfers sulfate to terminal and non-terminal beta 1, 4-linked N-acetylgalactosamine. J Biol Chem 276, 10861-9 (2001) (Pubitemid 38089263)
172. Okuda T., S. Mita, S. Yamauchi, M. Fukuta, H. Nakano, T. Sawada & O. Habuchi: Molecular cloning and characterization of GalNAc 4-sulfotransferase expressed in human pituitary gland. J Biol Chem 275, 40605-13 (2000) (Pubitemid 32064700)
173. Xia G., M. R. Evers, H. G. Kang, M. Schachner & J. U. Baenziger: Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase. J Biol Chem 275, 38402-9 (2000) (Pubitemid 32009164)
174. Hiraoka N., A. Misra, F. Belot, O. Hindsgaul & M. Fukuda: Molecular cloning and expression of two distinct human N-acetylgalactosamine 4-O-sulfotransferases that transfer sulfate to GalNAc beta 1->4GlcNAc beta 1->R in both N-and O-glycans. Glycobiology 11, 494-504 (2001)
175. Dharmesh S. M., T. P. Skelton & J. U. Baenziger: Coordinate and restricted expression of the ProXaaArg/Lysspecific GalNAc-transferase and the GalNAc beta 1, 4GlcNAc beta 1, 2Man alpha-4-sulfotransferase. J Biol Chem 268, 17096-102 (1993)
176. Woodworth A., D. Fiete & J. U. Baenziger: Spatial and temporal regulation of tenascin-R glycosylation in the cerebellum. J Biol Chem 277, 50941-7 (2002) (Pubitemid 36042262)
177. Woodworth A., P. Pesheva, D. Fiete & J. U. Baenziger: Neuronal-specific synthesis and glycosylation of tenascin-R. J Biol Chem 279, 10413-21 (2004) (Pubitemid 38372650)
178. Pesheva P. & R. Probstmeier: The yin and yang of tenascin-R in CNS development and pathology. Prog Neurobiol 61, 465-93 (2000) (Pubitemid 30169055)
179. Burudi E. M. & A. Regnier-Vigouroux: Regional and cellular expression of the mannose receptor in the postnatal developing mouse brain. Cell Tissue Res 303, 307-17 (2001) (Pubitemid 32250102)
180. Acheson A., J. L. Sunshine & U. Rutishauser: NCAM Polysialic acid can regulate both cell-cell and cell-substrate interactions. J Cell Biol 114, 143-153 (1991) (Pubitemid 21909787)
181. Franceschini I., S. Vitry, F. Padilla, P. Casanova, T. N. Tham, M. Fukuda, G. Rougon, P. Durbec & M. Dubois-Dalcq: Migrating and myelinating potential of neural precursors engineered to overexpress PSA-NCAM. Mol Cell Neurosci 27, 151-162 (2004) (Pubitemid 39370097)
182. Lavdas A. A., I. Franceschini, M. Dubois-Dalcq & R. Matsas: Schwann cells genetically engineered to express PSA show enhanced migratory potential without impairment of their myelinating ability in vitro. Glia 53, 868-878 (2006)
183. Tang J., U. Rutishauser & L. Landmesser: Polysialic acid regulates growth cone behavior during sorting of motor axons in the plexus region. Neuron 13, 405-414 (1994) (Pubitemid 24275097)
184. Tomasiewicz H., K. Ono, D. Yee, C. Thompson, C. Goridis, U. Rutishauser & T. Magnuson: Genetic deletion of a neural cell adhesion molecule variant (N-CAM-180) produces distinct defects in the central nervous system. Neuron 11, 1163-74 (1993) (Pubitemid 24015289)
185. Hu H., H. Tomasiewicz, T. Magnuson & U. Rutishauser: The role of polysialic acid in migration of olfactory bulb interneuron precursors in the subventricular zone. Neuron 16, 735-43 (1996) (Pubitemid 26124051)
186. Angata K., J. M. Long, O. Bukalo, W. Lee, A. Dityatev, A. Wynshaw-Boris, M. Schachner, M. Fukuda & J. D. Marth: Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior. J Biol Chem 279, 32603-13 (2004) (Pubitemid 39014717)
187. Becker C. G., A. Artola, R. Gerardy-Schahn, T. Becker, H. Welzl & M. Schachner: The polysialic acid modification of the neural cell adhesion molecule is involved in spatial learning and hippocampal long-term potentiation. J Neurosci Res 45, 143-52 (1996) (Pubitemid 26257315)
188. Cremer H., G. Chazal, A. Carleton, C. Goridis, J. D. Vincent & P. M. Lledo: Long-term but not short-term plasticity at mossy fiber synapses is impaired in neural cell adhesion molecule-deficient mice. Proc Natl Acad Sci U S A 95, 13242-7 (1998) (Pubitemid 28509556)
189. Cremer H., G. Chazal, C. Goridis & A. Represa: NCAM is essential for axonal growth and fasciculation in the hippocampus. Mol Cell Neurosci 8, 323-35 (1997) (Pubitemid 127796472)
190. Cremer H., R. Lange, A. Christoph, M. Plomann, G. Vopper, J. Roes, R. Brown, S. Baldwin, P. Kraemer, S. Scheff & et al.: Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature 367, 455-9 (1994) (Pubitemid 24046046)
191. Eckhardt M., O. Bukalo, G. Chazal, L. Wang, C. Goridis, M. Schachner, R. Gerardy-Schahn, H. Cremer & A. Dityatev: Mice deficient in the polysialyltransferase ST8SiaIV/PST-1 allow discrimination of the roles of neural cell adhesion molecule protein and polysialic acid in neural development and synaptic plasticity. J Neurosci 20, 5234-44 (2000) (Pubitemid 30457720)
192. Muller D., C. Wang, G. Skibo, N. Toni, H. Cremer, V. Calaora, G. Rougon & J. Z. Kiss: PSA-NCAM is required for activity-induced synaptic plasticity. Neuron 17, 413-22 (1996) (Pubitemid 26322213)
193. Seki T. & U. Rutishauser: Removal of polysialic acidneural cell adhesion molecule induces aberrant mossy fiber innervation and ectopic synaptogenesis in the hippocampus. J Neurosci 18, 3757-66 (1998) (Pubitemid 28225683)
194. Galuska S. P., I. Oltmann-Norden, H. Geyer, B. Weinhold, K. Kuchelmeister, H. Hildebrandt, R. Gerardy-Schahn, R. Geyer & M. Muhlenhoff: Polysialic acid profiles of mice expressing variant allelic combinations of the polysialyltransferases ST8SiaII and ST8SiaIV. J Biol Chem 281, 31605-31615 (2006) (Pubitemid 46041426)
195. Weinhold B., R. Seidenfaden, I. Rockle, M. Muhlenhoff, F. Schertzinger, S. Conzelmann, J. D. Marth, R. Gerardy-Schahn & H. Hildebrandt: Genetic ablation of polysialic acid causes severe neurodevelopmental defects rescued by deletion of the neural cell adhesion molecule. J Biol Chem 280, 42971-42977 (2005) (Pubitemid 43049260)
196. Artavanis-Tsakonas S., M. D. Rand & R. J. Lake: Notch signaling: cell fate control and signal integration in development. Science 284, 770-6 (1999) (Pubitemid 29291335)
197. Schweisguth F.: Regulation of Notch signaling activity. Current Biology 14, R129-R138 (2004) (Pubitemid 38215343)
198. Okajima T. & K. D. Irvine: Regulation of notch signaling by O-linked fucose. Cell 111, (2002)
199. Panin V. M., L. Shao, L. Lei, D. J. Moloney, K. D. Irvine & R. S. Haltiwanger: Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe. J Biol Chem 277, 29945-52 (2002)
200. Sasamura T., N. Sasaki, F. Miyashita, S. Nakao, H. O. Ishikawa, M. Ito, M. Kitagawa, K. Harigaya, E. Spana, D. Bilder, N. Perrimon & K. Matsuno: neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions. Development 130, 4785-4795 (2003) (Pubitemid 37321863)
201. Shi S. & P. Stanley: Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways. Proc Natl Acad Sci USA 100, 5234-5239 (2003) (Pubitemid 36542688)
202. Xu A., L. Lei & K. D. Irvine: Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe. J Biol Chem 280, 30158-30165 (2005) (Pubitemid 41216194)
203. Bruckner K., L. Perez, H. Clausen & S. Cohen: Glycosyltransferase activity of Fringe modulates Notch-Delta interactions. Nature 406, 411-415 (2000) (Pubitemid 30625560)
204. Moloney D. J., V. M. Panin, S. H. Johnston, J. Chen, L. Shao, R. Wilson, Y. Wang, P. Stanley, K. D. Irvine, R. S. Haltiwanger & T. F. Vogt: Fringe is a glycosyltransferase that modifies Notch. Nature 406, 369-375 (2000) (Pubitemid 30625549)
205. Okajima T., A. Xu & K. D. Irvine: Modulation of notch-ligand binding by protein O-fucosyltransferase and fringe. J Biol Chem 278, 42340-42345 (2003) (Pubitemid 37310503)
206. Panin V. M., V. Papayannopoulos, R. Wilson & K. D. Irvine: Fringe modulates Notch-ligand interactions. Nature 387, 908-912 (1997) (Pubitemid 27289592)
207. Lei L., A. Xu, V. M. Panin & K. D. Irvine: An O-fucose site in the ligand binding domain inhibits Notch activation. Development 130, 6411-6421 (2003) (Pubitemid 38088842)
208. Shao L., D. J. Moloney & R. S. Haltiwanger: Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region. J Biol Chem 278, 7775-7782 (2003) (Pubitemid 36800510)
209. Cordes R., K. Schuster-Gossler, K. Serth & A. Gossler: Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development 131, 1221-1233 (2004) (Pubitemid 38443877)
210. Serth K., K. Schuster-Gossler, R. Cordes & A. Gossler: Transcriptional oscillation of lunatic fringe is essential for somitogenesis. Genes & Development 17, 912-925 (2003) (Pubitemid 36397378)
211. Weinmaster G. & C. Kintner: Modulation of Notch signaling during somitogenesis. Annu Rev Dev Biol 19, 367-395 (2003) (Pubitemid 37487353)
212. de Celis S. F. & S. J. Bray: The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe. Development 127, 1291-1302 (2000) (Pubitemid 30179518)
213. Okajima T., A. Xu, L. Lei & K. D. Irvine: Chaperone activity of protein O-fucosyltransferase 1 promotes notch receptor folding. Science 307, 1599-1603 (2005) (Pubitemid 40354738)
214. Martin P. T. & H. H. Freeze: Glycobiology of neuromuscular disorders. Glycobiology 13, 67R-75R (2003) (Pubitemid 36939571)
215. Michele D. E. & K. P. Campbell: Dystrophinglycoprotein complex: Post-translational processing and dystroglycan function. J Biol Chem 278, 15457-15460 (2003) (Pubitemid 36799650)
216. Moore S. A., F. Saito, J. Chen, D. E. Michele, M. D. Henry, A. Messing, R. D. Cohn, S. E. Ross-Barta, S. Westra, R. A. Williamson, T. Hoshi & K. P. Campbell: Deletion of brain dystroglycan recapitulates aspects of congenital muscular dystrophy. Nature 418, 422-5 (2002) (Pubitemid 34826842)
217. Brockington M., S. Torelli, P. Prandini, C. Boito, N. F. Dolatshad, C. Longman, S. C. Brown & F. Muntoni: Localization and functional analysis of the LARGE family of glycosyltransferases: significance for muscular dystrophy. Hum Mol Genet 14, 657-665 (2005) (Pubitemid 40309591)
218. Henion T. R., Q. Qu & F. I. Smith: Expression of dystroglycan, fukutin and POMGnT1 during mouse cerebellar development. Brain Res Mol Brain Res 112, 177-181 (2003) (Pubitemid 36369260)
219. Ohtsuka-Tsurumi E., Y. Saito, T. Yamamoto, T. Voit, M. Kobayashi & M. Osawa: Co-localization of fukutin and alpha-dystroglycan in the mouse central nervous system. Brain Res Dev Brain Res 152, 121-127 (2004) (Pubitemid 39194826)
220. Qu Q. & F. I. Smith: Neuronal migration defects in cerebellum of the Largemyd mouse are associated with disruptions in Bergmann glia organization and delayed migration of granule neurons. Cerebellum 4, 261-270 (2005) (Pubitemid 43861187)
221. Ervasti J. M., A. L. Burwell & A. L. Geissler: Tissuespecific heterogeneity in alpha-dystroglycan sialoglycosylation. J Biol Chem 272, 22315-22321 (1997)
222. Martin P. T.: Dystroglycan glycosylation and its role in matrix binding in skeletal muscle. Glycobiology 13, 55R-66R (2003) (Pubitemid 36939570)
223. Barresi R., D. E. Michele, M. Kanagawa, H. A. Harper, S. A. Dovico, J. S. Satz, S. A. Moore, W. Zhang, H. Schachter, J. P. Dumanski, R. D. Cohn, I. Nishino & K. P. Campbell: Large can functionally bypass alphadystroglycan glycosylation defects in distinct congenital muscular dystrophies. Nat Med 10, 696-703 (2004) (Pubitemid 38937634)
224. Grewal P. K., J. M. McLaughlan, C. J. Moore, C. A. Browning & J. E. Hewitt: Characterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathies. Glycobiology 15, 912-923 (2005) (Pubitemid 41511487)
225. Kanagawa M., F. Saito, S. Kunz, T. Yoshida-Moriguchi, R. Baresi, Y. M. Kobayashi, J. Muschler, J. P. Dumanski, D. E. Michele, M. B. Oldstone & K. P. Campbell: Molecular recognition by LARGE is essential for expression of functional dystroglycan. Cell 117, 953-964 (2004) (Pubitemid 38798860)
226. Barresi R. & K. P. Campbell: Dystroglycan: from biosynthesis to pathogenesis of human disease. J Cell Sci 119, 199-207 (2006) (Pubitemid 43210689)
227. Coombs A. C. & J. M. Ervasti: Enhanced laminin binding by alpha-dystroglycan after enzymatic deglycosylation. Biochem J 390, 303-309 (2005) (Pubitemid 41192256)
228. Talts J. F., Z. Andac, W. Gohring, A. Brancaccio & R. Timpl: Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alphadystroglycan and several extracellular matrix proteins. Embo J 18, 863-70 (1999) (Pubitemid 29082266)
229. Sgambato A., A. Camerini, B. Faraglia, E. Pavoni, M. Montanari, D. Spada, C. Losasso, A. Brancaccio & A. Cittadini: Increased expression of dystroglycan inhibits the growth and tumorigenicity of human mammary epithelial cells. Cancer Biol Ther 3, 967-75 (2004) (Pubitemid 41351021)
230. Singh J., Y. Itahana, S. Knight-Krajewski, M. Kanagawa, K. P. Campbell, M. J. Bissell & J. Muschler: Proteolytic enzymes and altered glycosylation modulate dystroglycan function in carcinoma cells. Cancer Res 64, 6152-9 (2004) (Pubitemid 39129416)
231. Barry S. M., D. G. Zisoulis, J. W. Neal, N. A. Clipstone & G. S. Kansas: Induction of FucT-VII by the Ras/MAP kinase cascade in Jurkat T cells. Blood 102, 1771-1778 (2003) (Pubitemid 37022573)
232. Lim Y. C., L. Henault, A. J. Wagers, G. S. Kansas, F. W. Luscinskas & A. H. Lichtman: Expression of functional selectin ligands on Th cells is differentially regulated by IL-12 and IL-14. J Immunol 162, 3193-3201 (1999) (Pubitemid 29313565)
233. Seppo A., P. Matani, M. Sharrow & M. Tiemeyer: Induction of neuron-specific glycosylation by Tollo/Toll-8, a Drosophila Toll-like receptor expressed in non-neural cells. Development 130, 1439-1448 (2003) (Pubitemid 36410789)
234. Bellaiche Y., I. The & N. Perrimon: Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature 394, 85-88 (1998) (Pubitemid 28321807)
235. Bornemann D. J., J. E. Duncan, W. Staatz, S. Selleck & R. Warrior: Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways. Development 131, 1927-1938 (2004) (Pubitemid 38702028)
236. Hacker U., X. Lin & N. Perrimon: The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development 124, 3565-3573 (1997) (Pubitemid 27470040)
237. Lin X., E. M. Buff, N. Perrimon & A. M. Michelson: Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development 126, 3715-3723 (1999) (Pubitemid 29440471)
238. Toyoda H., A. Kinoshita-Toyoda, B. Fox & S. B. Selleck: Structural analysis of glycosaminoglycans in animals bearing mutations in sugarless, sulfateless, and tout-velu. Drosophila homologues of vertebrate genes encoding glycosaminoglycan biosynthetic enzymes. J Biol Chem 275, 21856-21861 (2000) (Pubitemid 30621755)
239. Inatani M. & Y. Yamaguchi: Gene expression of EXT1 and EXT2 during mouse brain development. Brain Res Dev Brain Res 141, 129-136 (2003) (Pubitemid 36315699)
240. Lin S., G. Wei, Z. Shi, L. Dryer, J. D. Esko, D. E. Wells & M. M. Matzuk: Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. Dev Biol 224, 299-311 (2000) (Pubitemid 30661012)
241. Inatani M., F. Irie, A. S. Plump, M. Tessier-Lavigne & Y. Yamaguchi: Mammalian brain morphogenesis and midline axon guidance require heparan sulfate. Science 302, 1044-1046 (2003) (Pubitemid 37386197)
242. Lin X. & N. Perrimon: Developmental roles of heparan sulfate proteoglycans in Drosophila. Glycoconj J 19, 363-368 (2002) (Pubitemid 37174567)
243. Esko J. D. & S. B. Selleck: Order out of chaos: assembly of ligand binding sites in heparan sulfate. Annu Rev Biochem 71, 435-71 (2002) (Pubitemid 34800227)
244. Yamaguchi Y.: Heparan sulfate proteoglycans in the nervous system: their diverse roles in neurogenesis, axon guidance, and synaptogenesis. Semin Cell Dev Biol 12, 99-106 (2001)
245. Bulow H. E. & O. Hobert: Differential sulfations and epimerization define heparan sulfate specificity in nervous system development. Neuron 41, 723-36 (2004) (Pubitemid 38326835)
246. Kreuger J., M. Salmivirta, L. Sturiale, G. Gimenez-Gallego & U. Lindahl: Sequence analysis of heparan sulfate epitopes with graded affinities for fibroblast growth factors 1 and 2. J Biol Chem 276, 30744-30752 (2001)
247. Pye D. A., R. R. Vives, P. Hyde & J. T. Gallagher: Regulation of FGF-1 mitogenic activity by heparan sulfate oligosaccharides is dependent on specific structural features: differential requirements for the modulation of FGF-1 and FGF-2. Glycobiology 10, 1183-1192 (2000)
248. Turnbull J. E., D. G. Fernig, Y. Ke, M. C. Wilkinson & J. T. Gallagher: Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate. J Biol Chem 267, 10337-10341 (1992)
249. Guimond S., M. Maccarana, B. B. Olwin, U. Lindahl & A. C. Rapraeger: Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4. J Biol Chem 268, 23906-23914 (1993) (Pubitemid 23335365)
250. Loo B. M., J. Kreuger, M. Jalkanen, U. Lindahl & M. Salmivirta: Binding of heparin/heparan sulfate to fibroblast growth factor receptor 4. J Biol Chem 276, 16868-16876 (2001)
251. Hienola A., M. Pekkanen, E. Raulo, P. Vanttola & H. Rauvala: HB-GAM inhibits proliferation and enhances differentiation of neural stem cells. Mol Cell Neurosci 26, 75-88 (2004) (Pubitemid 38581024)
252. Dono R., G. Texido, R. Dussel, H. Ehmke & R. Zeller: Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice. EMBO J 17, 4213-4225 (1998) (Pubitemid 28362612)
253. Raballo R., J. Rhee, R. Lyn-Cook, J. F. Leckman, M. L. Schwartz & F. M. Vaccarino: Basic fibroblast growth factor (Fgf2) is necessary for cell proliferation and neurogenesis in the developing cerebral cortex. J Neurosci 20, 5012-5023 (2000) (Pubitemid 30421705)
254. McLaughlin D., F. Karlsson, N. Tian, T. Pratt, S. L. Bullock, V. A. Wilson, D. J. Price & J. O. Mason: Specific modification of heparan sulphate is required for normal cerebral cortical development. Mech Dev 120, 1481-8 (2003) (Pubitemid 37488035)
255. Bullock S. L., J. M. Fletcher, R. S. Beddington & V. A. Wilson: Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes & Development 12, 1894-1906 (1998) (Pubitemid 28304341)
256. Kamimura K., M. Fujise, F. Villa, S. Izumi, H. Habuchi, K. Kimata & H. Nakato: Drosophila heparan sulfate 6-O-sulfotransferase (dHS6ST) gene. Structure, expression, and function in the formation of the tracheal system. J Biol Chem 276, 17014-17021 (2001)
257. Merry C. L., S. L. Bullock, D. C. Swan, A. C. Backen, M. Lyon, R. S. Beddington, V. A. Wilson & J. T. Gallagher: The molecular phenotype of heparan sulfate in the Hs2st-/-mutant mouse. J Biol Chem 276, 35429-35434 (2001)
258. Goodman C. S. & C. J. Shatz: Developmental mechanisms that generate precise patterns of neuronal connectivity. Cell 72, 77-98 (1993) (Pubitemid 23051238)
259. Huber A. B., A. L. Kolodkin, D. D. Ginty & J. F. Cloutier: Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance. Annu Rev Neurosci 26, 509-563 (2003) (Pubitemid 37064943)
260. Kidd T., K. Brose, K. J. Mitchell, R. D. Fetter, M. Tessier-Lavigne, C. S. Goodman & G. Tear: Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. Cell 92, 205-215 (1998) (Pubitemid 28073044)
261. Kidd T., K. S. Bland & C. S. Goodman: Slit is the midline repellent for the robo receptor in Drosophila. Cell 96, 785-794 (1999) (Pubitemid 29165082)
262. Long H., C. Sabatier, L. Ma, A. Plump, W. Yuan, D. M. Ornitz, A. Tamada, F. Murakami, C. S. Goodman & M. Tessier-Lavigne: Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron 42, 213-223 (2004) (Pubitemid 38501645)
263. Hu H.: Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein. Nat Neurosci 4, 695-701 (2001) (Pubitemid 32595407)
264. Johnson K. G., A. Ghose, E. Epstein, J. Lincecum, M. B. O'Connor & D. Van Vactor: Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellant slit during midline axon guidance. Current Biology 14, 499-504 (2004) (Pubitemid 38431285)
265. Steigemann P., A. Molitor, S. Fellert, H. Jackle & G. Vorbruggen: Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signaling. Curr Biol 14, 225-30 (2004) (Pubitemid 38215350)
266. Liang Y., R. S. Annan, S. A. Carr, S. Popp, M. Mevissen, R. K. Margolis & R. U. Margolis: Mammalian homologues of the Drosophila slit protein are ligands of the heparan sulfate proteoglycan glypican-1 in brain. J Biol Chem 274, 17885-17892 (1999)
267. Zhang F., F. Ronca, R. J. Linhardt & R. U. Margolis: Structural determinants of heparan sulfate interactions with Slit proteins. Biochem Biophys Res Commun 317, 352-357 (2004) (Pubitemid 38452489)
268. Rawson J. M., B. Dimitroff, K. G. Johnson, X. Ge, D. Van Vactor & S. B. Selleck: The heparan sulfate proteoglycans Dally-like and Syndecan have distinct functions in axon guidance and visual-system assembly in Drosophila. Curr Biol 15, 833-838 (2005) (Pubitemid 40689402)
269. Chen H., Z. He & M. Tessier-Lavigne: Axon guidance mechanisms: semaphorins as simultaneous repellants and anti-repellants. Nat Neurosci 1, 436-439 (1998)
270. Kantor D. B., O. Chivatakarn, K. L. Peer, S. F. Oster, M. Inatani, M. J. Hansen, J. G. Flanagan, Y. Yamaguchi, D. W. Sretavan, R. J. Giger & A. L. Kolodkin: Semaphorin 5A Is a Bifunctional Axon Guidance Cue Regulated by Heparan and Chondroitin Sulfate Proteoglycans. Neuron 44, 961-75 (2004) (Pubitemid 39643092)
271. Lowe J. B.: Glycan-dependent leukocyte adhesion and recruitment in inflammation. Curr Opin Cell Biol 15, 531-538 (2003) (Pubitemid 37176961)
272. Phillips M. L., E. Nudelman, F. C. Gaeta, M. Perez, A. K. Singhal, S. Hakomori & J. C. Paulson: ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex. Science 250, 1130-1132 (1990) (Pubitemid 120031820)
273. Tiemeyer M., S. J. Swiedler, M. Ishihara, M. Moreland, H. Schweingruber, P. Hirtzer & B. K. Brandley: Carbohydrate ligands for endothelial-leukocyte adhesion molecule 1. Proc Natl Acad Sci U S A 88, 1138-1142 (1991) (Pubitemid 21916180)
274. Whelan J.: Selectin synthesis and inflammation. Trends Biochem Sci 21, 65-69 (1996)
275. Springer T. A.: Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76, 301-324 (1994)
276. Angata K., S. C. Kerr, D. R. Greaves, N. M. Varki, P. R. Crocker & A. Varki: Cloning and characterization of human Siglec-11. A recently evolved signaling that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia. J Biol Chem 277, 24466-24474 (2002) (Pubitemid 34951971)
277. Galea I., K. Palin, T. A. Newman, N. Van Rooijen, V. H. Perry & D. Boche: Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain. Glia 49, 375-384 (2005) (Pubitemid 40222915)
278. Lee S. J. & E. N. Benveniste: Adhesion molecule expression and regulation on cells of the central nervous system. J Neuroimmunol 98, 77-8 (1999)
279. Leshko-Lindsay L. A. & V. G. Corces: The role of selectins in Drosophila eye and bristle development. Development 124, 169-180 (1997) (Pubitemid 27053017)
280. Regnier-Vigouroux A.: The mannose receptor in the brain. Int Rev Cytol 226, 321-342 (2003) (Pubitemid 36959358)
281. Sasaki N., J. Hirabayashi, H. Manya, K. Kasai & T. Endo: Galectin-1 induces astrocyte differentiation, which leads to production of brain-derived neurotrophic factor. Glycobiology 14, 357-363 (2004) (Pubitemid 38628113)
282. Tiemeyer M. & C. S. Goodman: Gliolectin is a novel carbohydrate-binding protein expressed by a subset of glia in the embryonic Drosophila nervous system. Development 122, 925-936 (1996) (Pubitemid 26098638)
283. Sharrow M. & M. Tiemeyer: Gliolectin-mediated carbohydrate binding at the Drosophila midline ensures the fidelity of axon pathfinding. Development 128, 4585-4595 (2001) (Pubitemid 33130438)
284. Lowe J. B. & J. D. Marth: A genetic approach to mammalian glycan function. Annu Rev Biochem 72, 643-691 (2003) (Pubitemid 36930456)